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The map label for this gene is dctS [H]

Identifier: 237813034

GI number: 237813034

Start: 2723172

End: 2725541

Strand: Direct

Name: dctS [H]

Synonym: GBP346_A2794

Alternate gene names: 237813034

Gene position: 2723172-2725541 (Clockwise)

Preceding gene: 237813029

Following gene: 237813035

Centisome position: 66.44

GC content: 66.75

Gene sequence:

>2370_bases
GTGGTGATGAGTCTCATTCTGTGGAGCCTCAATCGCCGCGAGGAGCAGCAGCAGGAAGACACGCTGTTTCGCAACGTCGC
GTGGGCGCAGCAGCAGATCCGCCTGTCGATGACGAGCGCGCAGGAACAGCTCCAGGCGTTCTCGCGCGACATCGCCGCGG
GCCGCATCGACGAGCATGCGTTCCAGGCGACGGTGGGCGACGTGATGCAGGCGCACCCCGAGATCCTCTATCTGAACTGG
TACACGTCGCCCGGCACGAAACGCTGGCCGACGATGCAATTGCCGCTCCTCGGCCAGCGGCTCGCGAAGCCGAACGACGC
GCAGATGGACGAAGTCGTGCGCGGCGCGTACGCGCAGGCGCGCGGCACGCGCCGCCAGTCGTACTCGCCGCTCGTCTACG
ACGACTTCGGCAACGGCTACCTGACGCTGCAAACGCCCGTGATCCGCGAGCGCGAGTATCTCGGCTCGATCGCCGCGGTG
TTCTCGGTCGAAGGCATCCTGAAGCACGACATCCCGCCCGAGCTGTCCGCGAAATACAAGATCTCGATCACCGACGCGAA
CAACCGCGAGCTCGCATCGACGTCGTCGCGCCCGCGGCTGCCGCGCGACGCGCATTACGACCTGCCGCTCGACCCGCCCG
GCCAGGGCCTCACGGTACGCGTCTACGCGTACCCGCAAACGACGAACCTGACCAACAACACGCTCGTATGGCTCGTCGCG
GGCCTGTCGTGCTTCGTGCTGTGGAGCCTCTGGAGCTTGTGGAAGCACACGCGGCAGCGCTTCGAGGCGCAGCAGGCGCT
GTACGCCGAGGCGTTCTTCCGCCGCGCGATGGAGAATTCGGTGCTGATCGGCATGCGCGTGCTCGACATGCACGGCCGGA
TCACGCACGTGAACCCGGCGTTCTGCCGGATGACGGGCTGGGACGAAAGCGACCTCGTCGGCAAGACCGCGCCGTTCCCG
TACTGGCCGCGCGACGCTTACCCGGAAATGCAGCGCCAGCTCGACATGACGCTGCGCGGCAAGGCGCCTTCGTCCGGCTT
CGAGCTGCGCGTGCGCCGCAAGGACGGCTCGCTCTTTCACGCACGCCTGTACGTATCGCCGCTCATCGACAGCGCCGGCC
GGCAGACGGGCTGGATGTCGTCGATGACCGACATCACCGAGCCCAAGCGCGCGCGCGAGGAGCTCGCGGCCGCGCACGAG
CGCTTCACGACAGTGCTCGAGAGCCTCGACGCCGCGGTGTCGGTGCTCGCCGCGGACGAAGCCGAGCTGCTGTTCGCGAA
CCGCTACTACCGGCACCTGTTCGGCATCCGCCCGGACGGCCACCTCGAACTGTCGGGCGGCGGCTTCGACACCGCGCAGG
CGTCGTCCGATTCGATCGACATGGTCGACGCCTACGCCGGCCTGCCCGCCGCGGCGCTCACCGAGAGCACGGCGGACGCG
CAGGAGGTGTACGTCGAGAGCATCCAGAAGTGGTTCGAGGTGCGCCGCCAGTACATCCAGTGGGTCGACGGCCACCTCGC
GCAGATGCAGATCGCGACCGACATCACGACGCGCAAGAAGGCGCAGGAGCTCGCGCACCAGCAGGAAGAAAAGCTGCAGT
TCACGAGCCGGCTGATGACGATGGGTGAAATGGCGTCGTCGATTGCACACGAACTGAACCAGCCGCTCGCGGCGATCAAC
AACTACTGCTCGGGCACGCTCGCGCTCGTGAAGAGCGGCCGCGCGTCGCCGGAGACGCTCGCGCCCGCGCTCGAGAAGAC
CGCGCAGCAGGCGCTGCGCGCCGGGATGATCGTCAAGCGGATCCGCGAGTTCGTCAAGCGCAGCGAGCCGAAGCGGCAGC
CGTCGCGGGTCGCCGACATCGTCGCCGACGCGGTCGGGCTCGCCGAAATCGAGGCGAGAAAGCGCCGGATTCGGATCGTC
ACCGAAATCCGCGCAAGAATGCCTATTATTTATGTCGACCCCGTGTTGATCGAGCAGGTGCTCGTGAACCTGATGAAGAA
CGCGGCCGAGGCGATGCAGGAGGCGCGGCCGCAGGCGGAGAACGGCGTGATCCGCGTCGTCGCCGACCTCGAGGCGGGTT
TCGTCGACATTCGCGTGATCGACCAGGGTCCGGGCGTCGACGAGGCGACGGCCGAACGCCTGTTCGAACCGTTCTACAGC
ACCAAGTCGGACGGGATGGGCATGGGGCTCAATATCTGCCGCTCGATCATCGAATCGCATCGCGGGCGTCTGTGGGTGGT
CAACAACGTCGAGCCGGACGGCCTCGTGTCGGGCGCGACGTTTCACTGCAGCCTGCCCATTGGGGAACCGGAGGATCTCG
GTCGCGGATCCGAGACATCGCCATCACAAACCGTAACGGGAGAGATATGA

Upstream 100 bases:

>100_bases
GGGCTCGCCTGCGGAGTCGCAGCCGTCCCGCTGGCACCACGGACCGTGGTGGTCCAACTCTTACCTGCTCACCCCCCTGC
TGTCGATCCTCGTCTTTCTC

Downstream 100 bases:

>100_bases
ATAGCCCTGTCACCACCTCACAGGAAACCGTCTTTGTCGTCGACGACGACGAGGCCGTGCGCGACTCGCTGCGCTGGCTG
CTGGAGGCAAACGGCTATCG

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 789; Mature: 789

Protein sequence:

>789_residues
MVMSLILWSLNRREEQQQEDTLFRNVAWAQQQIRLSMTSAQEQLQAFSRDIAAGRIDEHAFQATVGDVMQAHPEILYLNW
YTSPGTKRWPTMQLPLLGQRLAKPNDAQMDEVVRGAYAQARGTRRQSYSPLVYDDFGNGYLTLQTPVIREREYLGSIAAV
FSVEGILKHDIPPELSAKYKISITDANNRELASTSSRPRLPRDAHYDLPLDPPGQGLTVRVYAYPQTTNLTNNTLVWLVA
GLSCFVLWSLWSLWKHTRQRFEAQQALYAEAFFRRAMENSVLIGMRVLDMHGRITHVNPAFCRMTGWDESDLVGKTAPFP
YWPRDAYPEMQRQLDMTLRGKAPSSGFELRVRRKDGSLFHARLYVSPLIDSAGRQTGWMSSMTDITEPKRAREELAAAHE
RFTTVLESLDAAVSVLAADEAELLFANRYYRHLFGIRPDGHLELSGGGFDTAQASSDSIDMVDAYAGLPAAALTESTADA
QEVYVESIQKWFEVRRQYIQWVDGHLAQMQIATDITTRKKAQELAHQQEEKLQFTSRLMTMGEMASSIAHELNQPLAAIN
NYCSGTLALVKSGRASPETLAPALEKTAQQALRAGMIVKRIREFVKRSEPKRQPSRVADIVADAVGLAEIEARKRRIRIV
TEIRARMPIIYVDPVLIEQVLVNLMKNAAEAMQEARPQAENGVIRVVADLEAGFVDIRVIDQGPGVDEATAERLFEPFYS
TKSDGMGMGLNICRSIIESHRGRLWVVNNVEPDGLVSGATFHCSLPIGEPEDLGRGSETSPSQTVTGEI

Sequences:

>Translated_789_residues
MVMSLILWSLNRREEQQQEDTLFRNVAWAQQQIRLSMTSAQEQLQAFSRDIAAGRIDEHAFQATVGDVMQAHPEILYLNW
YTSPGTKRWPTMQLPLLGQRLAKPNDAQMDEVVRGAYAQARGTRRQSYSPLVYDDFGNGYLTLQTPVIREREYLGSIAAV
FSVEGILKHDIPPELSAKYKISITDANNRELASTSSRPRLPRDAHYDLPLDPPGQGLTVRVYAYPQTTNLTNNTLVWLVA
GLSCFVLWSLWSLWKHTRQRFEAQQALYAEAFFRRAMENSVLIGMRVLDMHGRITHVNPAFCRMTGWDESDLVGKTAPFP
YWPRDAYPEMQRQLDMTLRGKAPSSGFELRVRRKDGSLFHARLYVSPLIDSAGRQTGWMSSMTDITEPKRAREELAAAHE
RFTTVLESLDAAVSVLAADEAELLFANRYYRHLFGIRPDGHLELSGGGFDTAQASSDSIDMVDAYAGLPAAALTESTADA
QEVYVESIQKWFEVRRQYIQWVDGHLAQMQIATDITTRKKAQELAHQQEEKLQFTSRLMTMGEMASSIAHELNQPLAAIN
NYCSGTLALVKSGRASPETLAPALEKTAQQALRAGMIVKRIREFVKRSEPKRQPSRVADIVADAVGLAEIEARKRRIRIV
TEIRARMPIIYVDPVLIEQVLVNLMKNAAEAMQEARPQAENGVIRVVADLEAGFVDIRVIDQGPGVDEATAERLFEPFYS
TKSDGMGMGLNICRSIIESHRGRLWVVNNVEPDGLVSGATFHCSLPIGEPEDLGRGSETSPSQTVTGEI
>Mature_789_residues
MVMSLILWSLNRREEQQQEDTLFRNVAWAQQQIRLSMTSAQEQLQAFSRDIAAGRIDEHAFQATVGDVMQAHPEILYLNW
YTSPGTKRWPTMQLPLLGQRLAKPNDAQMDEVVRGAYAQARGTRRQSYSPLVYDDFGNGYLTLQTPVIREREYLGSIAAV
FSVEGILKHDIPPELSAKYKISITDANNRELASTSSRPRLPRDAHYDLPLDPPGQGLTVRVYAYPQTTNLTNNTLVWLVA
GLSCFVLWSLWSLWKHTRQRFEAQQALYAEAFFRRAMENSVLIGMRVLDMHGRITHVNPAFCRMTGWDESDLVGKTAPFP
YWPRDAYPEMQRQLDMTLRGKAPSSGFELRVRRKDGSLFHARLYVSPLIDSAGRQTGWMSSMTDITEPKRAREELAAAHE
RFTTVLESLDAAVSVLAADEAELLFANRYYRHLFGIRPDGHLELSGGGFDTAQASSDSIDMVDAYAGLPAAALTESTADA
QEVYVESIQKWFEVRRQYIQWVDGHLAQMQIATDITTRKKAQELAHQQEEKLQFTSRLMTMGEMASSIAHELNQPLAAIN
NYCSGTLALVKSGRASPETLAPALEKTAQQALRAGMIVKRIREFVKRSEPKRQPSRVADIVADAVGLAEIEARKRRIRIV
TEIRARMPIIYVDPVLIEQVLVNLMKNAAEAMQEARPQAENGVIRVVADLEAGFVDIRVIDQGPGVDEATAERLFEPFYS
TKSDGMGMGLNICRSIIESHRGRLWVVNNVEPDGLVSGATFHCSLPIGEPEDLGRGSETSPSQTVTGEI

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=28.75, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1788549, Length=270, Percent_Identity=27.037037037037, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786912, Length=124, Percent_Identity=34.6774193548387, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1790300, Length=255, Percent_Identity=25.0980392156863, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88457; Mature: 88457

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMSLILWSLNRREEQQQEDTLFRNVAWAQQQIRLSMTSAQEQLQAFSRDIAAGRIDEHA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
FQATVGDVMQAHPEILYLNWYTSPGTKRWPTMQLPLLGQRLAKPNDAQMDEVVRGAYAQA
HHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEECCHHHHHHCCCCCCHHHHHHHHHHHHH
RGTRRQSYSPLVYDDFGNGYLTLQTPVIREREYLGSIAAVFSVEGILKHDIPPELSAKYK
CCCCCCCCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
ISITDANNRELASTSSRPRLPRDAHYDLPLDPPGQGLTVRVYAYPQTTNLTNNTLVWLVA
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHH
GLSCFVLWSLWSLWKHTRQRFEAQQALYAEAFFRRAMENSVLIGMRVLDMHGRITHVNPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEECCHH
FCRMTGWDESDLVGKTAPFPYWPRDAYPEMQRQLDMTLRGKAPSSGFELRVRRKDGSLFH
HEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEECCCCCCCCEEEEEECCCCEEE
ARLYVSPLIDSAGRQTGWMSSMTDITEPKRAREELAAAHERFTTVLESLDAAVSVLAADE
EHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AELLFANRYYRHLFGIRPDGHLELSGGGFDTAQASSDSIDMVDAYAGLPAAALTESTADA
HHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHCCCCHHHHHCCCCHH
QEVYVESIQKWFEVRRQYIQWVDGHLAQMQIATDITTRKKAQELAHQQEEKLQFTSRLMT
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGEMASSIAHELNQPLAAINNYCSGTLALVKSGRASPETLAPALEKTAQQALRAGMIVKR
HHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IREFVKRSEPKRQPSRVADIVADAVGLAEIEARKRRIRIVTEIRARMPIIYVDPVLIEQV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHH
LVNLMKNAAEAMQEARPQAENGVIRVVADLEAGFVDIRVIDQGPGVDEATAERLFEPFYS
HHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHC
TKSDGMGMGLNICRSIIESHRGRLWVVNNVEPDGLVSGATFHCSLPIGEPEDLGRGSETS
CCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHCCCCCCCC
PSQTVTGEI
CCCCCCCCC
>Mature Secondary Structure
MVMSLILWSLNRREEQQQEDTLFRNVAWAQQQIRLSMTSAQEQLQAFSRDIAAGRIDEHA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
FQATVGDVMQAHPEILYLNWYTSPGTKRWPTMQLPLLGQRLAKPNDAQMDEVVRGAYAQA
HHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEECCHHHHHHCCCCCCHHHHHHHHHHHHH
RGTRRQSYSPLVYDDFGNGYLTLQTPVIREREYLGSIAAVFSVEGILKHDIPPELSAKYK
CCCCCCCCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
ISITDANNRELASTSSRPRLPRDAHYDLPLDPPGQGLTVRVYAYPQTTNLTNNTLVWLVA
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHH
GLSCFVLWSLWSLWKHTRQRFEAQQALYAEAFFRRAMENSVLIGMRVLDMHGRITHVNPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEECCHH
FCRMTGWDESDLVGKTAPFPYWPRDAYPEMQRQLDMTLRGKAPSSGFELRVRRKDGSLFH
HEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEECCCCCCCCEEEEEECCCCEEE
ARLYVSPLIDSAGRQTGWMSSMTDITEPKRAREELAAAHERFTTVLESLDAAVSVLAADE
EHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AELLFANRYYRHLFGIRPDGHLELSGGGFDTAQASSDSIDMVDAYAGLPAAALTESTADA
HHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHCCCCHHHHHCCCCHH
QEVYVESIQKWFEVRRQYIQWVDGHLAQMQIATDITTRKKAQELAHQQEEKLQFTSRLMT
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MGEMASSIAHELNQPLAAINNYCSGTLALVKSGRASPETLAPALEKTAQQALRAGMIVKR
HHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IREFVKRSEPKRQPSRVADIVADAVGLAEIEARKRRIRIVTEIRARMPIIYVDPVLIEQV
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHH
LVNLMKNAAEAMQEARPQAENGVIRVVADLEAGFVDIRVIDQGPGVDEATAERLFEPFYS
HHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHC
TKSDGMGMGLNICRSIIESHRGRLWVVNNVEPDGLVSGATFHCSLPIGEPEDLGRGSETS
CCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCCCCHHHCCCCCCCC
PSQTVTGEI
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]