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The map label for this gene is yheS [H]

Identifier: 237812826

GI number: 237812826

Start: 2517136

End: 2519076

Strand: Direct

Name: yheS [H]

Synonym: GBP346_A2580

Alternate gene names: 237812826

Gene position: 2517136-2519076 (Clockwise)

Preceding gene: 237812824

Following gene: 237812830

Centisome position: 61.41

GC content: 68.68

Gene sequence:

>1941_bases
GTGATCCGTTTCAATCAGTTCAGCCTCGCCCGCGGCACGAAGCCGCTCTTCGACGCGACCTCGTTCACGCTGAATCCCGG
CGAGAAGGCGGGCCTCGTCGGCGCGAACGGCGCCGGCAAATCCACGCTCTTCGCGGTGCTGCGCGGCGAGCTGCACGCGG
ACGCGGGCGACTTCTCGATGCCGCCGGCGTGGCGCATCGCGCACGTGTCGCAGGAAACGCCCGCCGTCGAGCGCAGCGCG
CTCGACTACACATTGGACGGCGACGCCGCGTTGCGCGCGATCGAGGCGCGCATCGCGCAGGCGTCCGCCGCGCACGACGG
CGCAGCCGAGGCCGACGCGCACGCGGCGTTCGCGGACGCCGACGGCTACACCGCGCCCGCGCGCGCCGAGGCGCTGCTGC
TCGGGCTCGGCTTCACGCTCGCGCAGACGCGCGAGCCCGTCGCGAGCTTCTCGGGCGGCTGGCGCATGCGCCTGAATCTC
GCGCAGGCGCTGATGTGCCGCTCGGATCTGCTGCTGCTCGACGAGCCGACGAACCACCTGGATCTCGACGCGATCGTCTG
GCTCGAAGACTGGCTGCATCGCTATTCGGGCACGCTCGTCATCATCTCGCACGATCGCGAATTCCTCGACGCCGTCTGCG
ACGTGACGCTGCATCTCGAGAATCGCCAGGTGAAGCGTTACGGCGGCAACTACTCGCAGTTCGAAGTGCTGCGCGCGCAG
CAGCTCGAATTGCAGCAAAGCGCATACGAAAAGCAGCAGAAGACGATTGCGCATCTGCAGAGCTTCGTCGACCGCTTCAA
GGCGAAGGCGTCGAAGGCGAAACAGGCGCAAAGCCGGGTGAAGGCGCTCGAGAAGATGGAGCGGATCGCGCCCGCGCACA
TCGCTTCGCCATTCACGTTCGAATTCCGCACGCCCGATTCCGCGCCGAACCCGATGCTCGTGATGGAAAACGTGCGCTGC
GGCTACCGCGCGGACGACGGCGGCGAGATCCCGATCGTCGAGCGCGTCGCGCTGTCGATCCAGAACGGCCAGCGCATCGG
CCTGCTCGGCGCGAACGGCCAGGGCAAGTCGACGCTCATCAAGACGCTCGCGGGCACGCTCGCGCCGCTGTCGGGCGAGC
TGCGCACCGGCCGCGGGCTCACGATCGGCTATTTCGCCCAGCACCAGCTCGAGACGCTGCGCGAGGACGATTCGGCGCTC
GCGCATCTCGCGCGCCTCGCCCCGGACACGCGCGAGCAGGAACTGCGCGACTTTCTCGGCGGCTTCAACTTCTCCGGCGA
GATGGCGACCGCGCCGATCGCGCCGTTCTCCGGCGGCGAGAAAGCGCGGCTCGCGCTCGCGCTGATCATCTGGCGGAAGC
CGAACCTGCTGCTGCTCGACGAGCCGACGAACCACCTCGATCTGGAAACGCGCCACGCGCTCACGATGGCGCTCGCGCAA
TTCGAGGGCACGCTGATCCTCGTGTCGCACGACCGTCACCTGCTGCGCGCGACGACCGACCAGTTCATGCTGGTCGCGAA
GCACCGGCTGCAGCCGTTCGACGGCGATCTCGACGACTACCGCGACTGGCTGCTGCAGCACGCGGCCGAACAGCGCGCGG
CGGCGAAGGCAGCCTGCGGCCCGGCGGGCGACGCCGACGGCGGCGCGCCCGCCGTGAATCGCAAGGACCAGAAACGGCAG
GAAGCCGAAGCGCGCCAGCGTCTGTCGCAGCTGAAGAAACCGCTGCAGGCGCGGATCACGAAGATCGAGAAGGAAATGGA
GCGGCTGCACGCGCAGAAGGCGGAGCTCGACGCGTTCGTCGCCGATCCGGCGAGCTATGCGGCGGACCAGAAGGCGCGGC
TCACCGATGCGATCCGCAAGCTCGGCGACGTCAACGGCCAGCTCGAAACGCTCGAGGCGGACTGGCTCGGCGCGCAGGAC
GAGCTGGAAAAAATCGGGTGA

Upstream 100 bases:

>100_bases
GTCTAGGCGAATTCGGCGCGGCGCGCACATTCCGCCATCCGGACGATCCCCCGAATGCGGCGCGCGGCTAGAATAACGGT
TTTCCCCAGCATTTCTCGCC

Downstream 100 bases:

>100_bases
CGAGCGCCGCACGGCAGCGGCATCGCAGCGCTGTCACGCGGCGTTCAGCGCCCGGGCGCCCGGGGCCGGGTTCTCGAGGC
TTGAAACTCAGCGCCGCGGC

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 646; Mature: 646

Protein sequence:

>646_residues
MIRFNQFSLARGTKPLFDATSFTLNPGEKAGLVGANGAGKSTLFAVLRGELHADAGDFSMPPAWRIAHVSQETPAVERSA
LDYTLDGDAALRAIEARIAQASAAHDGAAEADAHAAFADADGYTAPARAEALLLGLGFTLAQTREPVASFSGGWRMRLNL
AQALMCRSDLLLLDEPTNHLDLDAIVWLEDWLHRYSGTLVIISHDREFLDAVCDVTLHLENRQVKRYGGNYSQFEVLRAQ
QLELQQSAYEKQQKTIAHLQSFVDRFKAKASKAKQAQSRVKALEKMERIAPAHIASPFTFEFRTPDSAPNPMLVMENVRC
GYRADDGGEIPIVERVALSIQNGQRIGLLGANGQGKSTLIKTLAGTLAPLSGELRTGRGLTIGYFAQHQLETLREDDSAL
AHLARLAPDTREQELRDFLGGFNFSGEMATAPIAPFSGGEKARLALALIIWRKPNLLLLDEPTNHLDLETRHALTMALAQ
FEGTLILVSHDRHLLRATTDQFMLVAKHRLQPFDGDLDDYRDWLLQHAAEQRAAAKAACGPAGDADGGAPAVNRKDQKRQ
EAEARQRLSQLKKPLQARITKIEKEMERLHAQKAELDAFVADPASYAADQKARLTDAIRKLGDVNGQLETLEADWLGAQD
ELEKIG

Sequences:

>Translated_646_residues
MIRFNQFSLARGTKPLFDATSFTLNPGEKAGLVGANGAGKSTLFAVLRGELHADAGDFSMPPAWRIAHVSQETPAVERSA
LDYTLDGDAALRAIEARIAQASAAHDGAAEADAHAAFADADGYTAPARAEALLLGLGFTLAQTREPVASFSGGWRMRLNL
AQALMCRSDLLLLDEPTNHLDLDAIVWLEDWLHRYSGTLVIISHDREFLDAVCDVTLHLENRQVKRYGGNYSQFEVLRAQ
QLELQQSAYEKQQKTIAHLQSFVDRFKAKASKAKQAQSRVKALEKMERIAPAHIASPFTFEFRTPDSAPNPMLVMENVRC
GYRADDGGEIPIVERVALSIQNGQRIGLLGANGQGKSTLIKTLAGTLAPLSGELRTGRGLTIGYFAQHQLETLREDDSAL
AHLARLAPDTREQELRDFLGGFNFSGEMATAPIAPFSGGEKARLALALIIWRKPNLLLLDEPTNHLDLETRHALTMALAQ
FEGTLILVSHDRHLLRATTDQFMLVAKHRLQPFDGDLDDYRDWLLQHAAEQRAAAKAACGPAGDADGGAPAVNRKDQKRQ
EAEARQRLSQLKKPLQARITKIEKEMERLHAQKAELDAFVADPASYAADQKARLTDAIRKLGDVNGQLETLEADWLGAQD
ELEKIG
>Mature_646_residues
MIRFNQFSLARGTKPLFDATSFTLNPGEKAGLVGANGAGKSTLFAVLRGELHADAGDFSMPPAWRIAHVSQETPAVERSA
LDYTLDGDAALRAIEARIAQASAAHDGAAEADAHAAFADADGYTAPARAEALLLGLGFTLAQTREPVASFSGGWRMRLNL
AQALMCRSDLLLLDEPTNHLDLDAIVWLEDWLHRYSGTLVIISHDREFLDAVCDVTLHLENRQVKRYGGNYSQFEVLRAQ
QLELQQSAYEKQQKTIAHLQSFVDRFKAKASKAKQAQSRVKALEKMERIAPAHIASPFTFEFRTPDSAPNPMLVMENVRC
GYRADDGGEIPIVERVALSIQNGQRIGLLGANGQGKSTLIKTLAGTLAPLSGELRTGRGLTIGYFAQHQLETLREDDSAL
AHLARLAPDTREQELRDFLGGFNFSGEMATAPIAPFSGGEKARLALALIIWRKPNLLLLDEPTNHLDLETRHALTMALAQ
FEGTLILVSHDRHLLRATTDQFMLVAKHRLQPFDGDLDDYRDWLLQHAAEQRAAAKAACGPAGDADGGAPAVNRKDQKRQ
EAEARQRLSQLKKPLQARITKIEKEMERLHAQKAELDAFVADPASYAADQKARLTDAIRKLGDVNGQLETLEADWLGAQD
ELEKIG

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=534, Percent_Identity=39.1385767790262, Blast_Score=355, Evalue=1e-97,
Organism=Homo sapiens, GI10947137, Length=533, Percent_Identity=36.0225140712946, Blast_Score=324, Evalue=2e-88,
Organism=Homo sapiens, GI27881506, Length=533, Percent_Identity=36.0225140712946, Blast_Score=324, Evalue=2e-88,
Organism=Homo sapiens, GI10947135, Length=545, Percent_Identity=34.3119266055046, Blast_Score=265, Evalue=1e-70,
Organism=Homo sapiens, GI69354671, Length=545, Percent_Identity=34.3119266055046, Blast_Score=265, Evalue=1e-70,
Organism=Homo sapiens, GI153792144, Length=231, Percent_Identity=28.1385281385281, Blast_Score=70, Evalue=9e-12,
Organism=Homo sapiens, GI47078218, Length=223, Percent_Identity=27.8026905829596, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI45446740, Length=223, Percent_Identity=27.8026905829596, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI150417984, Length=217, Percent_Identity=29.4930875576037, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1789751, Length=645, Percent_Identity=53.6434108527132, Blast_Score=700, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=529, Percent_Identity=36.6729678638941, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1787182, Length=643, Percent_Identity=29.0824261275272, Blast_Score=211, Evalue=9e-56,
Organism=Escherichia coli, GI2367384, Length=545, Percent_Identity=30.8256880733945, Blast_Score=209, Evalue=5e-55,
Organism=Escherichia coli, GI87081782, Length=529, Percent_Identity=25.3308128544423, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1788165, Length=204, Percent_Identity=31.8627450980392, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787164, Length=199, Percent_Identity=31.6582914572864, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17553372, Length=532, Percent_Identity=36.0902255639098, Blast_Score=333, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI17555318, Length=513, Percent_Identity=36.0623781676413, Blast_Score=322, Evalue=3e-88,
Organism=Caenorhabditis elegans, GI17559834, Length=564, Percent_Identity=32.8014184397163, Blast_Score=300, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI17565586, Length=203, Percent_Identity=29.064039408867, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71992285, Length=207, Percent_Identity=25.1207729468599, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=556, Percent_Identity=34.1726618705036, Blast_Score=320, Evalue=5e-88,
Organism=Saccharomyces cerevisiae, GI6320874, Length=537, Percent_Identity=32.7746741154562, Blast_Score=287, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6324314, Length=386, Percent_Identity=30.8290155440415, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6325030, Length=391, Percent_Identity=30.9462915601023, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6323278, Length=385, Percent_Identity=29.3506493506493, Blast_Score=154, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24666836, Length=528, Percent_Identity=38.4469696969697, Blast_Score=375, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24642252, Length=551, Percent_Identity=37.7495462794918, Blast_Score=349, Evalue=3e-96,
Organism=Drosophila melanogaster, GI18859989, Length=551, Percent_Identity=37.7495462794918, Blast_Score=349, Evalue=3e-96,
Organism=Drosophila melanogaster, GI24641342, Length=548, Percent_Identity=34.6715328467153, Blast_Score=310, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 70903; Mature: 70903

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRFNQFSLARGTKPLFDATSFTLNPGEKAGLVGANGAGKSTLFAVLRGELHADAGDFSM
CCEECCCHHCCCCCCCCCCCCEEECCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCC
PPAWRIAHVSQETPAVERSALDYTLDGDAALRAIEARIAQASAAHDGAAEADAHAAFADA
CCCCEEEECCCCCCCHHHHCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECC
DGYTAPARAEALLLGLGFTLAQTREPVASFSGGWRMRLNLAQALMCRSDLLLLDEPTNHL
CCCCCCHHHHEEEEECCHHHHHHHCHHHHCCCCEEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAIVWLEDWLHRYSGTLVIISHDREFLDAVCDVTLHLENRQVKRYGGNYSQFEVLRAQ
CCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHCEEEEECCCHHHHHCCCHHHHHHHHHH
QLELQQSAYEKQQKTIAHLQSFVDRFKAKASKAKQAQSRVKALEKMERIAPAHIASPFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCEEE
EFRTPDSAPNPMLVMENVRCGYRADDGGEIPIVERVALSIQNGQRIGLLGANGQGKSTLI
EEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHEECCCCEEEEEECCCCCHHHHH
KTLAGTLAPLSGELRTGRGLTIGYFAQHQLETLREDDSALAHLARLAPDTREQELRDFLG
HHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHC
GFNFSGEMATAPIAPFSGGEKARLALALIIWRKPNLLLLDEPTNHLDLETRHALTMALAQ
CCCCCCCCCCCCCCCCCCCCHHEEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHH
FEGTLILVSHDRHLLRATTDQFMLVAKHRLQPFDGDLDDYRDWLLQHAAEQRAAAKAACG
HCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PAGDADGGAPAVNRKDQKRQEAEARQRLSQLKKPLQARITKIEKEMERLHAQKAELDAFV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADPASYAADQKARLTDAIRKLGDVNGQLETLEADWLGAQDELEKIG
CCCHHHHCCHHHHHHHHHHHHHCCCCCEEEEEHHHCCCHHHHHHCC
>Mature Secondary Structure
MIRFNQFSLARGTKPLFDATSFTLNPGEKAGLVGANGAGKSTLFAVLRGELHADAGDFSM
CCEECCCHHCCCCCCCCCCCCEEECCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCC
PPAWRIAHVSQETPAVERSALDYTLDGDAALRAIEARIAQASAAHDGAAEADAHAAFADA
CCCCEEEECCCCCCCHHHHCCCEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECC
DGYTAPARAEALLLGLGFTLAQTREPVASFSGGWRMRLNLAQALMCRSDLLLLDEPTNHL
CCCCCCHHHHEEEEECCHHHHHHHCHHHHCCCCEEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAIVWLEDWLHRYSGTLVIISHDREFLDAVCDVTLHLENRQVKRYGGNYSQFEVLRAQ
CCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHCEEEEECCCHHHHHCCCHHHHHHHHHH
QLELQQSAYEKQQKTIAHLQSFVDRFKAKASKAKQAQSRVKALEKMERIAPAHIASPFTF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCEEE
EFRTPDSAPNPMLVMENVRCGYRADDGGEIPIVERVALSIQNGQRIGLLGANGQGKSTLI
EEECCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHEECCCCEEEEEECCCCCHHHHH
KTLAGTLAPLSGELRTGRGLTIGYFAQHQLETLREDDSALAHLARLAPDTREQELRDFLG
HHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHC
GFNFSGEMATAPIAPFSGGEKARLALALIIWRKPNLLLLDEPTNHLDLETRHALTMALAQ
CCCCCCCCCCCCCCCCCCCCHHEEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHH
FEGTLILVSHDRHLLRATTDQFMLVAKHRLQPFDGDLDDYRDWLLQHAAEQRAAAKAACG
HCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PAGDADGGAPAVNRKDQKRQEAEARQRLSQLKKPLQARITKIEKEMERLHAQKAELDAFV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ADPASYAADQKARLTDAIRKLGDVNGQLETLEADWLGAQDELEKIG
CCCHHHHCCHHHHHHHHHHHHHCCCCCEEEEEHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]