Click here to switch to the map view.

The map label for this gene is pyrH [H]

Identifier: 237812806

GI number: 237812806

Start: 2492099

End: 2492959

Strand: Reverse

Name: pyrH [H]

Synonym: GBP346_A2560

Alternate gene names: 237812806

Gene position: 2492959-2492099 (Counterclockwise)

Preceding gene: 237812807

Following gene: 237812805

Centisome position: 60.83

GC content: 67.6

Gene sequence:

>861_bases
TTGACCCGCGGCGGACGACCGTTGCGCCGCGGTCGGCAGCGCCGCCTGACGGGGCTCTCAGCCAGCCCGGCCCGGCGGCG
CTTGCCCGAACCAGCATTTCGCCCCTACAGTTCGTGCTTGTCATCCTCTCGTCGCTCGGAAGTCCCTATGCCCAATGCCT
ATAAACGCGTCCTCCTCAAACTTTCCGGCGAAGCTCTGATGGGCGACGATGCCTTCGGCATCAATCGCGCGACGATCGAG
CGGATGGTTGCCGACATCGCGGAAGTCGTGCGTCTCGGCACGCAGCTTGCGGTCGTGATCGGCGGGGGCAACATCTTTCG
CGGCGTCGCGGGCGGCGCGGCCGGCATGGACCGCGCGACGGCCGACTACATGGGGATGCTCGCGACGATGATGAACGCGC
TCGCGCTGCAGGACGCGATGCGCCACGCGGGCATCGAGGCGCGCGTGCAGTCGGCGCTGCGCATGGACCAGGTGGTCGAG
CCGTACATCCGCCCGCGCGCGATCCGCCAGCTCGAGGAGGGCAAGGTGGTGATCTTCGCGGCGGGCACGGGCAACCCGTT
CTTCACGACGGACACGGCGGCCGCGCTGCGCGGCTCGGAAGTCGGCGCCGAGGTGGTGCTGAAGGCGACGAAGGTCGACG
GCGTCTACTCGGCCGATCCGAAGAAGGACCCGTCGGCGACGCGCTATTCGTCGATCAGCTTCGACGAGGCGATCGGCCGC
AACCTGCAGGTGATGGACGCGACGGCGTTCGCGCTCTGCCGCGACCAGAAGCTGCCGATCCGCGTGTTTTCGATCAACAA
GCCGGGTGCGCTCAAACGTATCGTTCAAGGAGAGGACGAGGGCACGCTCGTCCACGTGTAA

Upstream 100 bases:

>100_bases
ATCGAGAAGCGCCAGGACGACTTCGCCGCGGAAGTGGCCGCGCAAGTCGCCGCCGCGAAGCAGCAGTAACCAGTCGTAAA
AGCAGTAACCAGCAGTACGC

Downstream 100 bases:

>100_bases
ACTCTCGCCGATGCGGGAGGCCGCGGCGCCGCGCGCCGCCTTTGGCCATTGCCCGTATCGTTTTGAAGTTCGGAAGGTTC
GGAGGTTGAAATGAGTGTCG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MTRGGRPLRRGRQRRLTGLSASPARRRLPEPAFRPYSSCLSSSRRSEVPMPNAYKRVLLKLSGEALMGDDAFGINRATIE
RMVADIAEVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVE
PYIRPRAIRQLEEGKVVIFAAGTGNPFFTTDTAAALRGSEVGAEVVLKATKVDGVYSADPKKDPSATRYSSISFDEAIGR
NLQVMDATAFALCRDQKLPIRVFSINKPGALKRIVQGEDEGTLVHV

Sequences:

>Translated_286_residues
MTRGGRPLRRGRQRRLTGLSASPARRRLPEPAFRPYSSCLSSSRRSEVPMPNAYKRVLLKLSGEALMGDDAFGINRATIE
RMVADIAEVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVE
PYIRPRAIRQLEEGKVVIFAAGTGNPFFTTDTAAALRGSEVGAEVVLKATKVDGVYSADPKKDPSATRYSSISFDEAIGR
NLQVMDATAFALCRDQKLPIRVFSINKPGALKRIVQGEDEGTLVHV
>Mature_285_residues
TRGGRPLRRGRQRRLTGLSASPARRRLPEPAFRPYSSCLSSSRRSEVPMPNAYKRVLLKLSGEALMGDDAFGINRATIER
MVADIAEVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVEP
YIRPRAIRQLEEGKVVIFAAGTGNPFFTTDTAAALRGSEVGAEVVLKATKVDGVYSADPKKDPSATRYSSISFDEAIGRN
LQVMDATAFALCRDQKLPIRVFSINKPGALKRIVQGEDEGTLVHV

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=231, Percent_Identity=57.5757575757576, Blast_Score=280, Evalue=6e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 30879; Mature: 30748

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRGGRPLRRGRQRRLTGLSASPARRRLPEPAFRPYSSCLSSSRRSEVPMPNAYKRVLLK
CCCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LSGEALMGDDAFGINRATIERMVADIAEVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRAT
HCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHCCCCCCCCHHH
ADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIRQLEEGKVVIFA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEEE
AGTGNPFFTTDTAAALRGSEVGAEVVLKATKVDGVYSADPKKDPSATRYSSISFDEAIGR
ECCCCCCEECCHHHHHCCCCCCHHHEEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHCC
NLQVMDATAFALCRDQKLPIRVFSINKPGALKRIVQGEDEGTLVHV
CEEEEHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCCCCEEEC
>Mature Secondary Structure 
TRGGRPLRRGRQRRLTGLSASPARRRLPEPAFRPYSSCLSSSRRSEVPMPNAYKRVLLK
CCCCCHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LSGEALMGDDAFGINRATIERMVADIAEVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRAT
HCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHCCCCCCCCHHH
ADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIRQLEEGKVVIFA
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCEEEEE
AGTGNPFFTTDTAAALRGSEVGAEVVLKATKVDGVYSADPKKDPSATRYSSISFDEAIGR
ECCCCCCEECCHHHHHCCCCCCHHHEEEEECCCCEECCCCCCCCCCCCCCCCCHHHHHCC
NLQVMDATAFALCRDQKLPIRVFSINKPGALKRIVQGEDEGTLVHV
CEEEEHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA