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The map label for this gene is frr [H]

Identifier: 237812805

GI number: 237812805

Start: 2491448

End: 2492008

Strand: Reverse

Name: frr [H]

Synonym: GBP346_A2559

Alternate gene names: 237812805

Gene position: 2492008-2491448 (Counterclockwise)

Preceding gene: 237812806

Following gene: 237812804

Centisome position: 60.8

GC content: 63.28

Gene sequence:

>561_bases
ATGAGTGTCGCTGATATCAAGAAGAGCGTCGAGCAGAAGATGCAGCGCTCGATCGAAGCGTTCAAGAACGATCTGGCGAA
GATCCGCACGGGCCGTGCGCATACCGGTCTGCTCGATCACGTGCAGGTCGACTACTACGGCTCGATGGTGCCGATCTCGC
AGGTCGCGAACCTGACGCTCGTCGACGCGCGCACGATCGGCGTGCAGCCGTGGGAAAAGACCATGGTCGCGAAGGTCGAG
AAGGCGATCCGCGAAGCCGATCTGGGCCTGAACCCGGCGACGTCGGGCGACCTGATCCGCGTGCCGATGCCGCCGCTCAC
CGAGGAGCGCCGCCGCGAGCTGACGAAGGTGGTCAAGAGCGAAGGCGAAACGGCGAAGGTCGCCGTGCGCAATCTGCGCC
GCGACGCGAACGAGCAACTGAAGAAGCTCGTGAAGGACAAGGAAATTTCCGAAGACGACGAGCGCCGCGCGAGCGACGAC
GTGCAGAAGCTGACGGACAAGCACGTCGCGGAGATCGACAAGCTCGTCCAGGCCAAGGACGCGGAGATCATGACGGTCTG
A

Upstream 100 bases:

>100_bases
CCACGTGTAAACTCTCGCCGATGCGGGAGGCCGCGGCGCCGCGCGCCGCCTTTGGCCATTGCCCGTATCGTTTTGAAGTT
CGGAAGGTTCGGAGGTTGAA

Downstream 100 bases:

>100_bases
AGCCGCCTTGCGTCGCACTTTTTCCTGCAGCTACAGTCTCAGCGGCCATGACCTATACCAGCTCTACCGTTCGCGTGCCT
GACGTCGCCGCCGTGCCGCG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSVADIKKSVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTLVDARTIGVQPWEKTMVAKVE
KAIREADLGLNPATSGDLIRVPMPPLTEERRRELTKVVKSEGETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRASDD
VQKLTDKHVAEIDKLVQAKDAEIMTV

Sequences:

>Translated_186_residues
MSVADIKKSVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTLVDARTIGVQPWEKTMVAKVE
KAIREADLGLNPATSGDLIRVPMPPLTEERRRELTKVVKSEGETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRASDD
VQKLTDKHVAEIDKLVQAKDAEIMTV
>Mature_185_residues
SVADIKKSVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTLVDARTIGVQPWEKTMVAKVEK
AIREADLGLNPATSGDLIRVPMPPLTEERRRELTKVVKSEGETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRASDDV
QKLTDKHVAEIDKLVQAKDAEIMTV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=177, Percent_Identity=32.2033898305085, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI291042689, Length=151, Percent_Identity=32.4503311258278, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=53.8461538461538, Blast_Score=209, Evalue=6e-56,
Organism=Drosophila melanogaster, GI24661488, Length=178, Percent_Identity=28.0898876404494, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20899; Mature: 20768

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVADIKKSVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCE
VDARTIGVQPWEKTMVAKVEKAIREADLGLNPATSGDLIRVPMPPLTEERRRELTKVVKS
ECHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHC
EGETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRASDDVQKLTDKHVAEIDKLVQAKD
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AEIMTV
CCEECC
>Mature Secondary Structure 
SVADIKKSVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHCCCE
VDARTIGVQPWEKTMVAKVEKAIREADLGLNPATSGDLIRVPMPPLTEERRRELTKVVKS
ECHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHC
EGETAKVAVRNLRRDANEQLKKLVKDKEISEDDERRASDDVQKLTDKHVAEIDKLVQAKD
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AEIMTV
CCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA