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The map label for this gene is argE [H]

Identifier: 237812720

GI number: 237812720

Start: 2418571

End: 2419788

Strand: Direct

Name: argE [H]

Synonym: GBP346_A2473

Alternate gene names: 237812720

Gene position: 2418571-2419788 (Clockwise)

Preceding gene: 237812718

Following gene: 237812721

Centisome position: 59.01

GC content: 68.23

Gene sequence:

>1218_bases
ATGTCCGTTCTCGACGCAACGGCACCGTCCGCGTCCTCATCCTCCTCGTTGGCCGAACCGATCAGCCTCTCATGGGTCAA
GCAGCTCGTCTCGATCGACACGACGAGCCGCGTGCCGAATCTCGGCCTCATCGAAATGGTTCGCGACGCGCTCGCGGCGG
CCGGCGTCGAATCGACGCTCACGCACGATGCCCGTGACGGCTGGGCGAACCTGTTCGCGACGATCCCCGCGCACGACGGC
ACGACGAACGGCGGCATCGTGCTGTCGGGCCACACCGACGTCGTGCCCGTGGACGGCCAGCAATGGGACAGCGATCCGTT
CAAGCCGCAAGTGCGCGACGGCAAGCTCTACGGGCGCGGCACCTGTGACATGAAAGGCTTCATCGGCGCGGCGCTCGCGT
TGCTGCCCGAAATGCAGGCGGCCAAGCTCGCACAGCCGCTTCACTTCGCGCTGTCGTTCGACGAGGAGATCGGCTGCGTC
GGCGCGCCGCTACTGCTCGCCGATCTGAAGGCGCGCGGCGTCGCGCCCGCCGGCTGCATCGTCGGCGAGCCGACCGGCAT
GCGCCCCGTGATCGCGCACAAGGGCATCAACGTCTACCGCTGCTGCGTGCGCGGCCACGCCGCGCATTCGTCGCTCACGC
CGAAGGGCCTGAACGCGATCGAATACGCGGCGCGCCTCATCTGCCACATCCGCGACCTCGCCGACGAATTCCGCGCGCAA
GGCCCGTTCGACGCACTGTACGACGTGCCGTTCACGACCGCGCAAACGAGCCTCATCCAGGGCGGCAACGCGGTCAACAC
GGTGCCCGCCGAATGCCAGTTCTCGTTCGAGTTCCGCAATTTGCCGACGCTCGATCCCGACGCGATCTTCGCGCGCATCG
ATGCATACGCGCGCGACACGCTGCTGCCGCGGATGCGCCGCGAGCATCCGAACGCGGCGATCGAGTTCTCGAAGGTCGCC
GCCGCGCCCGGCCTCGACGCGGCCGAGCAGGCGGCGATCACCGAACTCGTGCGCTCGCTCACCGCCGATCAGGAAAAGCG
CAAGGTCGCCTACGGCACCGAGGCGGGCCTGTTCCAGCGCGCGGGCATTCCGAGCGTCGTCTGCGGGCCCGGCTACATCG
AGCAGGCGCACAAGCCGAACGAGTTCGTCGAACTCGAGCAGCTCGCGTCGTGCGAGCGCTTCGTGCGCAAGCTCGTGCAG
GGCATGACGCTCGCGTAA

Upstream 100 bases:

>100_bases
ACGCACCGGATGCTGCGCCGCAAAGCGTCGCGCGAAGACGGGCCGCGCCGTTTTTGAGTATGATCTTTGCATTCGTTCGC
CTCTCTGCCGGAGTCCCGCC

Downstream 100 bases:

>100_bases
GCCCGCGCCGCACTCCGTTCCGGCCGTCCGCTCGGCCGCCGTCATCGATACGCGCACGCCCATGTCGACCTCACCCAACC
GCCCCGCTCATCTGACGATC

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSVLDATAPSASSSSSLAEPISLSWVKQLVSIDTTSRVPNLGLIEMVRDALAAAGVESTLTHDARDGWANLFATIPAHDG
TTNGGIVLSGHTDVVPVDGQQWDSDPFKPQVRDGKLYGRGTCDMKGFIGAALALLPEMQAAKLAQPLHFALSFDEEIGCV
GAPLLLADLKARGVAPAGCIVGEPTGMRPVIAHKGINVYRCCVRGHAAHSSLTPKGLNAIEYAARLICHIRDLADEFRAQ
GPFDALYDVPFTTAQTSLIQGGNAVNTVPAECQFSFEFRNLPTLDPDAIFARIDAYARDTLLPRMRREHPNAAIEFSKVA
AAPGLDAAEQAAITELVRSLTADQEKRKVAYGTEAGLFQRAGIPSVVCGPGYIEQAHKPNEFVELEQLASCERFVRKLVQ
GMTLA

Sequences:

>Translated_405_residues
MSVLDATAPSASSSSSLAEPISLSWVKQLVSIDTTSRVPNLGLIEMVRDALAAAGVESTLTHDARDGWANLFATIPAHDG
TTNGGIVLSGHTDVVPVDGQQWDSDPFKPQVRDGKLYGRGTCDMKGFIGAALALLPEMQAAKLAQPLHFALSFDEEIGCV
GAPLLLADLKARGVAPAGCIVGEPTGMRPVIAHKGINVYRCCVRGHAAHSSLTPKGLNAIEYAARLICHIRDLADEFRAQ
GPFDALYDVPFTTAQTSLIQGGNAVNTVPAECQFSFEFRNLPTLDPDAIFARIDAYARDTLLPRMRREHPNAAIEFSKVA
AAPGLDAAEQAAITELVRSLTADQEKRKVAYGTEAGLFQRAGIPSVVCGPGYIEQAHKPNEFVELEQLASCERFVRKLVQ
GMTLA
>Mature_404_residues
SVLDATAPSASSSSSLAEPISLSWVKQLVSIDTTSRVPNLGLIEMVRDALAAAGVESTLTHDARDGWANLFATIPAHDGT
TNGGIVLSGHTDVVPVDGQQWDSDPFKPQVRDGKLYGRGTCDMKGFIGAALALLPEMQAAKLAQPLHFALSFDEEIGCVG
APLLLADLKARGVAPAGCIVGEPTGMRPVIAHKGINVYRCCVRGHAAHSSLTPKGLNAIEYAARLICHIRDLADEFRAQG
PFDALYDVPFTTAQTSLIQGGNAVNTVPAECQFSFEFRNLPTLDPDAIFARIDAYARDTLLPRMRREHPNAAIEFSKVAA
APGLDAAEQAAITELVRSLTADQEKRKVAYGTEAGLFQRAGIPSVVCGPGYIEQAHKPNEFVELEQLASCERFVRKLVQG
MTLA

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=363, Percent_Identity=32.7823691460055, Blast_Score=171, Evalue=9e-44,
Organism=Escherichia coli, GI1788816, Length=338, Percent_Identity=27.5147928994083, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 43258; Mature: 43126

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLDATAPSASSSSSLAEPISLSWVKQLVSIDTTSRVPNLGLIEMVRDALAAAGVESTL
CCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHCCHHHHH
THDARDGWANLFATIPAHDGTTNGGIVLSGHTDVVPVDGQQWDSDPFKPQVRDGKLYGRG
HHHHHHHHHHHEEEECCCCCCCCCCEEEECCCCEEECCCCCCCCCCCCCCCCCCEEECCC
TCDMKGFIGAALALLPEMQAAKLAQPLHFALSFDEEIGCVGAPLLLADLKARGVAPAGCI
CCCHHHHHHHHHHHHCCHHHHHHHCHHHEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCE
VGEPTGMRPVIAHKGINVYRCCVRGHAAHSSLTPKGLNAIEYAARLICHIRDLADEFRAQ
ECCCCCCCCHHHHCCCHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
GPFDALYDVPFTTAQTSLIQGGNAVNTVPAECQFSFEFRNLPTLDPDAIFARIDAYARDT
CCCHHHHCCCCCHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHH
LLPRMRREHPNAAIEFSKVAAAPGLDAAEQAAITELVRSLTADQEKRKVAYGTEAGLFQR
HHHHHHHHCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHH
AGIPSVVCGPGYIEQAHKPNEFVELEQLASCERFVRKLVQGMTLA
CCCCCEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SVLDATAPSASSSSSLAEPISLSWVKQLVSIDTTSRVPNLGLIEMVRDALAAAGVESTL
CCCCCCCCCCCCCCHHCCCHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHCCHHHHH
THDARDGWANLFATIPAHDGTTNGGIVLSGHTDVVPVDGQQWDSDPFKPQVRDGKLYGRG
HHHHHHHHHHHEEEECCCCCCCCCCEEEECCCCEEECCCCCCCCCCCCCCCCCCEEECCC
TCDMKGFIGAALALLPEMQAAKLAQPLHFALSFDEEIGCVGAPLLLADLKARGVAPAGCI
CCCHHHHHHHHHHHHCCHHHHHHHCHHHEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCE
VGEPTGMRPVIAHKGINVYRCCVRGHAAHSSLTPKGLNAIEYAARLICHIRDLADEFRAQ
ECCCCCCCCHHHHCCCHHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
GPFDALYDVPFTTAQTSLIQGGNAVNTVPAECQFSFEFRNLPTLDPDAIFARIDAYARDT
CCCHHHHCCCCCHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHH
LLPRMRREHPNAAIEFSKVAAAPGLDAAEQAAITELVRSLTADQEKRKVAYGTEAGLFQR
HHHHHHHHCCCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHH
AGIPSVVCGPGYIEQAHKPNEFVELEQLASCERFVRKLVQGMTLA
CCCCCEEECCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]