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The map label for this gene is msrB [H]

Identifier: 237812657

GI number: 237812657

Start: 2361801

End: 2362286

Strand: Direct

Name: msrB [H]

Synonym: GBP346_A2407

Alternate gene names: 237812657

Gene position: 2361801-2362286 (Clockwise)

Preceding gene: 237812656

Following gene: 237812658

Centisome position: 57.62

GC content: 64.61

Gene sequence:

>486_bases
GTGACGCCGCCGGCACGCCGCGCGTTGCGCATGAATTCATCAGGAGAATCGAAGATGTCAGGAGATCGAGACGACCCGCG
TTATCCCTACCCGAAGGACGACGCCGAGCTGCGCCGCCGGCTCACGCCGATGCAGTACGAGGTCACGCAGCACGCGGCGA
CCGAGCCGCCGTTCACCGGCGAGTACACGGACACCGAGGACGCGGGCATCTATCATTGCGTCGTGTGCGGCACCGCGCTG
TTCGAATCGGGCGCGAAATTCCACTCGGGCTGCGGCTGGCCCAGCTACTTCAAGCCGATCGACGGCGAGGTGATCGACGA
GAAGATGGACTACACGCACGGCATGACCCGCGTCGAGGTGCGCTGCAACCAGTGCGGCGCGCATCTCGGCCACGTGTTCG
AGGACGGCCCGCGCGACAAAACCGGATTGCGGTACTGCATCAACTCGGCTGCGTTAAACTTCGAGGCTAAGCCCGAGCGC
AAGTGA

Upstream 100 bases:

>100_bases
CGGCCGTGCTGCGGCGCCCGTTCGACGAGCAGCCGGAGCACGACGCGTATGCGGCGCTGCCGCCCGACTGGGCGAGCACG
CTCGAGGTGAGCTGCTCGTC

Downstream 100 bases:

>100_bases
GCACGGGCCGGCCGAAGAGCCGGCCCGCGCGCCGCGACGGGGCGTCCCTACAACGGTGGCGGGCCCAACGCCCGCCCGCA
GCCGCGAGCACCATGAAATT

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MTPPARRALRMNSSGESKMSGDRDDPRYPYPKDDAELRRRLTPMQYEVTQHAATEPPFTGEYTDTEDAGIYHCVVCGTAL
FESGAKFHSGCGWPSYFKPIDGEVIDEKMDYTHGMTRVEVRCNQCGAHLGHVFEDGPRDKTGLRYCINSAALNFEAKPER
K

Sequences:

>Translated_161_residues
MTPPARRALRMNSSGESKMSGDRDDPRYPYPKDDAELRRRLTPMQYEVTQHAATEPPFTGEYTDTEDAGIYHCVVCGTAL
FESGAKFHSGCGWPSYFKPIDGEVIDEKMDYTHGMTRVEVRCNQCGAHLGHVFEDGPRDKTGLRYCINSAALNFEAKPER
K
>Mature_160_residues
TPPARRALRMNSSGESKMSGDRDDPRYPYPKDDAELRRRLTPMQYEVTQHAATEPPFTGEYTDTEDAGIYHCVVCGTALF
ESGAKFHSGCGWPSYFKPIDGEVIDEKMDYTHGMTRVEVRCNQCGAHLGHVFEDGPRDKTGLRYCINSAALNFEAKPERK

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI37620216, Length=119, Percent_Identity=63.0252100840336, Blast_Score=157, Evalue=3e-39,
Organism=Homo sapiens, GI301336164, Length=119, Percent_Identity=63.0252100840336, Blast_Score=157, Evalue=3e-39,
Organism=Homo sapiens, GI301336162, Length=119, Percent_Identity=63.0252100840336, Blast_Score=157, Evalue=3e-39,
Organism=Homo sapiens, GI73089054, Length=119, Percent_Identity=63.0252100840336, Blast_Score=157, Evalue=3e-39,
Organism=Homo sapiens, GI117606353, Length=134, Percent_Identity=45.5223880597015, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1788077, Length=119, Percent_Identity=52.9411764705882, Blast_Score=142, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17553450, Length=154, Percent_Identity=42.8571428571429, Blast_Score=126, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI115532676, Length=150, Percent_Identity=43.3333333333333, Blast_Score=123, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6319816, Length=161, Percent_Identity=37.888198757764, Blast_Score=107, Evalue=1e-24,
Organism=Drosophila melanogaster, GI221378664, Length=120, Percent_Identity=52.5, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24645799, Length=153, Percent_Identity=45.0980392156863, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI221378662, Length=127, Percent_Identity=51.1811023622047, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI45553335, Length=120, Percent_Identity=52.5, Blast_Score=129, Evalue=9e-31,
Organism=Drosophila melanogaster, GI21356369, Length=120, Percent_Identity=52.5, Blast_Score=129, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24645801, Length=164, Percent_Identity=42.6829268292683, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24645804, Length=131, Percent_Identity=48.8549618320611, Blast_Score=123, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 18142; Mature: 18011

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPARRALRMNSSGESKMSGDRDDPRYPYPKDDAELRRRLTPMQYEVTQHAATEPPFTG
CCCHHHHHEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCC
EYTDTEDAGIYHCVVCGTALFESGAKFHSGCGWPSYFKPIDGEVIDEKMDYTHGMTRVEV
CCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEE
RCNQCGAHLGHVFEDGPRDKTGLRYCINSAALNFEAKPERK
EHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TPPARRALRMNSSGESKMSGDRDDPRYPYPKDDAELRRRLTPMQYEVTQHAATEPPFTG
CCHHHHHEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCC
EYTDTEDAGIYHCVVCGTALFESGAKFHSGCGWPSYFKPIDGEVIDEKMDYTHGMTRVEV
CCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEE
RCNQCGAHLGHVFEDGPRDKTGLRYCINSAALNFEAKPERK
EHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA