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The map label for this gene is arnT2 [H]

Identifier: 237812593

GI number: 237812593

Start: 2307616

End: 2309322

Strand: Direct

Name: arnT2 [H]

Synonym: GBP346_A2343

Alternate gene names: 237812593

Gene position: 2307616-2309322 (Clockwise)

Preceding gene: 237812592

Following gene: 237812594

Centisome position: 56.3

GC content: 68.66

Gene sequence:

>1707_bases
ATGAACGATACGCCGACGAGGCTACCGCTCGATCGCGCCGCGCCCATGACGCTGAACCGCGCCGCGCTCCTCCTTCTCGT
CGCGGCGCTCGCCGTGATCTGGTTCGCGCCGCTCGGCCTGCGCCATCTGATTCCGAGCGACGAAGGGCGCTACGCCGAAA
TGGCCCGCGAGATGTTCGTCACGGGCGACTGGATCACGCCGCGCTACAACGGCTACAAGTATTTCGAGAAGCCGCCGCTG
CAGACCTGGCTCAACGCGCTCACGTTCGCGTGGTTCGGCATCGGCGAATGGCAGGCGCGCCTGTACACGGCGCTCGCGAG
CTTCGCGGGCGTGCTCTTCGCCGGCTACGCCGGCGCGCGCGTGTTCAACCCGCGCGCGGGCTTTTTCGCGGCGCTCGTGC
TCGCGAGCTCGCCGTACTGGAACCTGATGGGCCACTTCAACGCGCTCGACATGGGGCTGTCGCTGTGGATGACGGTCACG
CTCTGCGCGCTGCTGCTCGCGCAGCGCCCCGGCATCGGCAAGCGCGCCGAGCGCGGCTGGATGTGGCTCTGCTGGGCGTC
GATGGCCCTCGCCGTGCTGTCGAAGGGCCTGATCGGCCTGATCCTGCCGGGCGCCGTGCTCGTCCTCTACACGCTCGCGT
CCCGCGACTGGGCGCTGTGGAAACGCCTGCACCTCGTGAGCGGCCTCGTCATCTTCTTCGCGATCGCGACACCCTGGTTC
GTGCTCGTGCAGTCGCGCAACCCCGAGTTCTTCAACTTCTTCTTCATCGTCCAGCAGTTCCGGCGCTACCTGACGCCCGA
GCAGAACCGCCCCGGCGCGTTCTACTACTTCGCGCCGGTGCTCGCCGTCGGCTTCCTGCCGTGGCTGTCCGTGAGCGTGC
AGAGCGTGCGCCACGCGCTGCGCATCCCGCGCCAGCCGAACGGCTTCGCGCCGATGCTCATGCTCGCGACGTGGAGCGTG
TTCATCTTCCTGTTCTTCAGCGCGTCCCATTCGAAGCTGATCTCGTACGTGCTGCCGGTGGCGCCCGCGCTCGCGCTGAT
GATCGGCGCGTATCTGCCGCTCGTGTCGCGCGAGCAGTTCCGCCGCCATCTGTTCGGCTACCTGGTATTTCTCGTCGCCG
CCGCATTCGGCACGCTTTTCCTCGCGCGGCTGGGCGACGCACGCACGCCGAATTCGCAGTACCTGGAATTCCAGAAATGG
GTGTACGTGGCGCTCGCCGCGGCGTTCGCGCTCACGCTCGTCGCCGTCTGGCTCAACCGCCGCGGCCGCGCGGGCGTCGC
GGCGGCGGCCGTCGCGTTCGGCGCCGGCTGGCTGCTCCTCGGCACGATCGGCGGCACCGGGCACGACGCGTTCGGCCGCT
ACAGCTCGGGCGCGCTCCTCGCGCCCGCGATCCGCGAGGAACTCGCGAAGCTGCCGCCCGACACGCCGTTCTATTCCGTC
GAGACGCTCGATCACACGCTGCCGTTCTACGTCGGCCACACGATGATCATGGTCGAGCGCAAGGACGAGCTCACGTTCGG
CATCTCGGTCGAGCCGAACAAGTGGGTGCCGACCGTCGCCGAATGGGAGCAGCGCTGGCGCGCCGATCGCCACGCGCTCG
CGCTGATGTCGCCCGACCGCTACAAGCAGTTATCGGAGGCCGGCCTGCCGATGCGCGTCGTCGCACGCGACAACCGGCGC
GTCGTCGTCGAGAAGCCGCAATCCTGA

Upstream 100 bases:

>100_bases
CGCCCCGCTTCGCGCCGCGGCCCGGGCGCCGCGAACGACGGCCGCGAACGACAGCCGCACTCCGCCCCGACCGAATTCGA
ACCACTCCAATACGACTTCT

Downstream 100 bases:

>100_bases
GCCGCGAAGGACCCGAATCGATGAACCCCGTCTCCCTCTTTTGCATCGTCACGGGCGTGATGCTGAACGCCTGCGCGCAA
CTGCTGCTGAAAGCCGGCGT

Product: dolichyl-phosphate-mannose-protein mannosyltransferase family protein

Products: NA

Alternate protein names: 4-amino-4-deoxy-L-arabinose lipid A transferase 2; Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase; Undecaprenyl phosphate-alpha-L-Ara4N transferase 2 [H]

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MNDTPTRLPLDRAAPMTLNRAALLLLVAALAVIWFAPLGLRHLIPSDEGRYAEMAREMFVTGDWITPRYNGYKYFEKPPL
QTWLNALTFAWFGIGEWQARLYTALASFAGVLFAGYAGARVFNPRAGFFAALVLASSPYWNLMGHFNALDMGLSLWMTVT
LCALLLAQRPGIGKRAERGWMWLCWASMALAVLSKGLIGLILPGAVLVLYTLASRDWALWKRLHLVSGLVIFFAIATPWF
VLVQSRNPEFFNFFFIVQQFRRYLTPEQNRPGAFYYFAPVLAVGFLPWLSVSVQSVRHALRIPRQPNGFAPMLMLATWSV
FIFLFFSASHSKLISYVLPVAPALALMIGAYLPLVSREQFRRHLFGYLVFLVAAAFGTLFLARLGDARTPNSQYLEFQKW
VYVALAAAFALTLVAVWLNRRGRAGVAAAAVAFGAGWLLLGTIGGTGHDAFGRYSSGALLAPAIREELAKLPPDTPFYSV
ETLDHTLPFYVGHTMIMVERKDELTFGISVEPNKWVPTVAEWEQRWRADRHALALMSPDRYKQLSEAGLPMRVVARDNRR
VVVEKPQS

Sequences:

>Translated_568_residues
MNDTPTRLPLDRAAPMTLNRAALLLLVAALAVIWFAPLGLRHLIPSDEGRYAEMAREMFVTGDWITPRYNGYKYFEKPPL
QTWLNALTFAWFGIGEWQARLYTALASFAGVLFAGYAGARVFNPRAGFFAALVLASSPYWNLMGHFNALDMGLSLWMTVT
LCALLLAQRPGIGKRAERGWMWLCWASMALAVLSKGLIGLILPGAVLVLYTLASRDWALWKRLHLVSGLVIFFAIATPWF
VLVQSRNPEFFNFFFIVQQFRRYLTPEQNRPGAFYYFAPVLAVGFLPWLSVSVQSVRHALRIPRQPNGFAPMLMLATWSV
FIFLFFSASHSKLISYVLPVAPALALMIGAYLPLVSREQFRRHLFGYLVFLVAAAFGTLFLARLGDARTPNSQYLEFQKW
VYVALAAAFALTLVAVWLNRRGRAGVAAAAVAFGAGWLLLGTIGGTGHDAFGRYSSGALLAPAIREELAKLPPDTPFYSV
ETLDHTLPFYVGHTMIMVERKDELTFGISVEPNKWVPTVAEWEQRWRADRHALALMSPDRYKQLSEAGLPMRVVARDNRR
VVVEKPQS
>Mature_568_residues
MNDTPTRLPLDRAAPMTLNRAALLLLVAALAVIWFAPLGLRHLIPSDEGRYAEMAREMFVTGDWITPRYNGYKYFEKPPL
QTWLNALTFAWFGIGEWQARLYTALASFAGVLFAGYAGARVFNPRAGFFAALVLASSPYWNLMGHFNALDMGLSLWMTVT
LCALLLAQRPGIGKRAERGWMWLCWASMALAVLSKGLIGLILPGAVLVLYTLASRDWALWKRLHLVSGLVIFFAIATPWF
VLVQSRNPEFFNFFFIVQQFRRYLTPEQNRPGAFYYFAPVLAVGFLPWLSVSVQSVRHALRIPRQPNGFAPMLMLATWSV
FIFLFFSASHSKLISYVLPVAPALALMIGAYLPLVSREQFRRHLFGYLVFLVAAAFGTLFLARLGDARTPNSQYLEFQKW
VYVALAAAFALTLVAVWLNRRGRAGVAAAAVAFGAGWLLLGTIGGTGHDAFGRYSSGALLAPAIREELAKLPPDTPFYSV
ETLDHTLPFYVGHTMIMVERKDELTFGISVEPNKWVPTVAEWEQRWRADRHALALMSPDRYKQLSEAGLPMRVVARDNRR
VVVEKPQS

Specific function: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG1807

COG function: function code M; 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 83 family [H]

Homologues:

Organism=Escherichia coli, GI1788591, Length=383, Percent_Identity=27.154046997389, Blast_Score=139, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022839
- InterPro:   IPR003342 [H]

Pfam domain/function: PF02366 PMT [H]

EC number: =2.4.2.43 [H]

Molecular weight: Translated: 63711; Mature: 63711

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTPTRLPLDRAAPMTLNRAALLLLVAALAVIWFAPLGLRHLIPSDEGRYAEMAREMFV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
TGDWITPRYNGYKYFEKPPLQTWLNALTFAWFGIGEWQARLYTALASFAGVLFAGYAGAR
CCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCE
VFNPRAGFFAALVLASSPYWNLMGHFNALDMGLSLWMTVTLCALLLAQRPGIGKRAERGW
EECCCHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
MWLCWASMALAVLSKGLIGLILPGAVLVLYTLASRDWALWKRLHLVSGLVIFFAIATPWF
EHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCE
VLVQSRNPEFFNFFFIVQQFRRYLTPEQNRPGAFYYFAPVLAVGFLPWLSVSVQSVRHAL
EEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
RIPRQPNGFAPMLMLATWSVFIFLFFSASHSKLISYVLPVAPALALMIGAYLPLVSREQF
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RRHLFGYLVFLVAAAFGTLFLARLGDARTPNSQYLEFQKWVYVALAAAFALTLVAVWLNR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RGRAGVAAAAVAFGAGWLLLGTIGGTGHDAFGRYSSGALLAPAIREELAKLPPDTPFYSV
CCCCHHHHHHHHHCCCEEEEEECCCCCCHHCCCCCCCCEECHHHHHHHHHCCCCCCCEEH
ETLDHTLPFYVGHTMIMVERKDELTFGISVEPNKWVPTVAEWEQRWRADRHALALMSPDR
HHHHCCCHHHHCCEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHEEEECCCHH
YKQLSEAGLPMRVVARDNRRVVVEKPQS
HHHHHHCCCCEEEEECCCCEEEEECCCC
>Mature Secondary Structure
MNDTPTRLPLDRAAPMTLNRAALLLLVAALAVIWFAPLGLRHLIPSDEGRYAEMAREMFV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
TGDWITPRYNGYKYFEKPPLQTWLNALTFAWFGIGEWQARLYTALASFAGVLFAGYAGAR
CCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCE
VFNPRAGFFAALVLASSPYWNLMGHFNALDMGLSLWMTVTLCALLLAQRPGIGKRAERGW
EECCCHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCE
MWLCWASMALAVLSKGLIGLILPGAVLVLYTLASRDWALWKRLHLVSGLVIFFAIATPWF
EHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCE
VLVQSRNPEFFNFFFIVQQFRRYLTPEQNRPGAFYYFAPVLAVGFLPWLSVSVQSVRHAL
EEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
RIPRQPNGFAPMLMLATWSVFIFLFFSASHSKLISYVLPVAPALALMIGAYLPLVSREQF
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RRHLFGYLVFLVAAAFGTLFLARLGDARTPNSQYLEFQKWVYVALAAAFALTLVAVWLNR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RGRAGVAAAAVAFGAGWLLLGTIGGTGHDAFGRYSSGALLAPAIREELAKLPPDTPFYSV
CCCCHHHHHHHHHCCCEEEEEECCCCCCHHCCCCCCCCEECHHHHHHHHHCCCCCCCEEH
ETLDHTLPFYVGHTMIMVERKDELTFGISVEPNKWVPTVAEWEQRWRADRHALALMSPDR
HHHHCCCHHHHCCEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHEEEECCCHH
YKQLSEAGLPMRVVARDNRRVVVEKPQS
HHHHHHCCCCEEEEECCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA