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The map label for this gene is comL [H]

Identifier: 237812528

GI number: 237812528

Start: 2244367

End: 2245209

Strand: Direct

Name: comL [H]

Synonym: GBP346_A2277

Alternate gene names: 237812528

Gene position: 2244367-2245209 (Clockwise)

Preceding gene: 237812516

Following gene: 237812533

Centisome position: 54.76

GC content: 64.29

Gene sequence:

>843_bases
ATGCGAGCCCTTTTCACCATGATGCATTCGACCAAACGCGTCGCAAAACCTGCGGCCGCCTGGGCCGCGCTGGCGGCGGC
CGCGGCGCTCGTCGCGGGTTGCCACGGCTTGCCGCAGAAGAGCGATGAGACGGCAACCTGGTCGAACAACAAATTATACT
CAGAGGCTCAGGATGCATTGACGGGCGGCGACTGGGGCAAGTGCGCGAAGTACTTCGAGGCGCTGCAAGGCCGCGATCCG
TTCGGCCACTTCGCGCAACAGGCGCAGATCAACGTCGCCTACTGCAACTGGAAGGACAACGAAACGGCCGCCGCCGATCA
GGCGGTCGACCGCTTCATCCAGTTGCACCCGGATCACCCGGACGTCGCGTATGCGTACTACCTGAAGGGGATGATCCACT
TCAACGACGACCTGGGCCTGTTCGGCCGCTTCTCCGGCCAGGACATGAGCGAGCGCGATCCGCAGGCGCTGCGCGAATCG
TACGATGCGTTCAAGGTCGTCGTCGACCGCTATCCGAAGAGCAAGTACGCGCCCGACGCGGCCGCGCGCATGCGCTACAT
CGTCAACGCGCTCGCGTCGCACGAAGTGCACGCGGCCGACTACTACTACCGGCGCGGCGCCTATGTCGCGGCGATCAACC
GCGCGCAGCTTGCGATCAAGGAATACAAGAACGCGCCGGCGATCGAGGACGCGCTGCACATCATGATGCTGTCGTACGCG
AAGCTGAATCAGCCGCAGCTCGCCGACGACACGAAGCGCGTGCTCGCCTCGACATTCCCGGACAGCCCGTACGTGACCGG
CCACGCGCGGCCGGGCTCGAAGAAATCGTGGTGGCAATTCTGA

Upstream 100 bases:

>100_bases
CTTGGGCTATAATCGTCGCGGTTTGACTTGCCCGCACGGGCATTCAACGAACTTGAACGGGTCATTTAGACTGGGTCACT
TGAGACTTGAAGCTAGGACA

Downstream 100 bases:

>100_bases
GCTGAGCGTCGCGATTCGCGCTGCGTGCGCGACCGATGGTGCGCGATCGGCGCATCGACAAAGAAACCCGGCCTGTCGAG
CCGGGTTTTTCTTTTCGCGC

Product: competence lipoprotein ComL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MRALFTMMHSTKRVAKPAAAWAALAAAAALVAGCHGLPQKSDETATWSNNKLYSEAQDALTGGDWGKCAKYFEALQGRDP
FGHFAQQAQINVAYCNWKDNETAAADQAVDRFIQLHPDHPDVAYAYYLKGMIHFNDDLGLFGRFSGQDMSERDPQALRES
YDAFKVVVDRYPKSKYAPDAAARMRYIVNALASHEVHAADYYYRRGAYVAAINRAQLAIKEYKNAPAIEDALHIMMLSYA
KLNQPQLADDTKRVLASTFPDSPYVTGHARPGSKKSWWQF

Sequences:

>Translated_280_residues
MRALFTMMHSTKRVAKPAAAWAALAAAAALVAGCHGLPQKSDETATWSNNKLYSEAQDALTGGDWGKCAKYFEALQGRDP
FGHFAQQAQINVAYCNWKDNETAAADQAVDRFIQLHPDHPDVAYAYYLKGMIHFNDDLGLFGRFSGQDMSERDPQALRES
YDAFKVVVDRYPKSKYAPDAAARMRYIVNALASHEVHAADYYYRRGAYVAAINRAQLAIKEYKNAPAIEDALHIMMLSYA
KLNQPQLADDTKRVLASTFPDSPYVTGHARPGSKKSWWQF
>Mature_280_residues
MRALFTMMHSTKRVAKPAAAWAALAAAAALVAGCHGLPQKSDETATWSNNKLYSEAQDALTGGDWGKCAKYFEALQGRDP
FGHFAQQAQINVAYCNWKDNETAAADQAVDRFIQLHPDHPDVAYAYYLKGMIHFNDDLGLFGRFSGQDMSERDPQALRES
YDAFKVVVDRYPKSKYAPDAAARMRYIVNALASHEVHAADYYYRRGAYVAAINRAQLAIKEYKNAPAIEDALHIMMLSYA
KLNQPQLADDTKRVLASTFPDSPYVTGHARPGSKKSWWQF

Specific function: Required for efficient transformation of Neisseria gonorrhoeae by species-related DNA [H]

COG id: COG4105

COG function: function code R; DNA uptake lipoprotein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0169 (ComL) family [H]

Homologues:

Organism=Escherichia coli, GI1788947, Length=238, Percent_Identity=34.8739495798319, Blast_Score=157, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017689
- InterPro:   IPR011990 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 31311; Mature: 31311

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRALFTMMHSTKRVAKPAAAWAALAAAAALVAGCHGLPQKSDETATWSNNKLYSEAQDAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
TGGDWGKCAKYFEALQGRDPFGHFAQQAQINVAYCNWKDNETAAADQAVDRFIQLHPDHP
CCCCHHHHHHHHHHHCCCCCHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCC
DVAYAYYLKGMIHFNDDLGLFGRFSGQDMSERDPQALRESYDAFKVVVDRYPKSKYAPDA
CHHHHHHHHHHEEECCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCH
AARMRYIVNALASHEVHAADYYYRRGAYVAAINRAQLAIKEYKNAPAIEDALHIMMLSYA
HHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
KLNQPQLADDTKRVLASTFPDSPYVTGHARPGSKKSWWQF
HCCCCCCCHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCC
>Mature Secondary Structure
MRALFTMMHSTKRVAKPAAAWAALAAAAALVAGCHGLPQKSDETATWSNNKLYSEAQDAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
TGGDWGKCAKYFEALQGRDPFGHFAQQAQINVAYCNWKDNETAAADQAVDRFIQLHPDHP
CCCCHHHHHHHHHHHCCCCCHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCC
DVAYAYYLKGMIHFNDDLGLFGRFSGQDMSERDPQALRESYDAFKVVVDRYPKSKYAPDA
CHHHHHHHHHHEEECCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCH
AARMRYIVNALASHEVHAADYYYRRGAYVAAINRAQLAIKEYKNAPAIEDALHIMMLSYA
HHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
KLNQPQLADDTKRVLASTFPDSPYVTGHARPGSKKSWWQF
HCCCCCCCHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8830266 [H]