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The map label for this gene is ybiT [H]

Identifier: 237812509

GI number: 237812509

Start: 2221524

End: 2223323

Strand: Reverse

Name: ybiT [H]

Synonym: GBP346_A2258

Alternate gene names: 237812509

Gene position: 2223323-2221524 (Counterclockwise)

Preceding gene: 237812510

Following gene: 237812507

Centisome position: 54.25

GC content: 63.17

Gene sequence:

>1800_bases
ATGCGCGGCATGCCGCCGAACGGCACGCGCAAGCCGCGCACGCGACGGCCGATCGATTTGGCGCCATTTCTTCGTTTCCG
CTCTCGGCCGGAAAAGAGCGCATGGCCCGTGCGTTTTCGGGGCCCGAAGCGCATGCGGCGCAGCGATTCATCGACTCCTG
CTAAAATACCCGGTTTTCCGTCGATCTATCTCCTAACGGGATCTGCCGTGCTTTCTACCGCCAACATCACGATGCAATTC
GGGCCCAAGCCCCTGTTCGAGAACATCTCGGTCAAGTTCGGGGAGGGCAACCGCTACGGCCTCATCGGGGCGAACGGCTG
CGGCAAGTCGACCTTCATGAAGATCCTGGGCGGCGATCTGGAGCCGTCGGCGGGCAACGTCGCGCTCGAGCCGAACGTGC
GGCTCGGCAAGCTGCGCCAGGATCAGTTCGCATACGAGGACGTGCGCGTGCTCGACGTCGTGATGATGGGCCACACCGAG
ATGTGGGCCGCGATGACCGAGCGCGACGCGATCTACGCGAACCCCGAGGCGACCGACGACGACTACATGCACGCGGCCGA
ACTCGAGGCGAAGTTCGCCGAGTACGGCGGCTACGACGCCGAGGCGCGCGCGGGCGCGCTGCTGCTCGGCATCGGCATCG
AGGAGAAGTTCCACAGCGGCCCGATGCGCGACGTCGCGCCGGGCTGGAAGCTGCGGGTGCTGCTCGCGCAGGCGCTGTTC
TCGAACCCGGACGTGCTGCTGCTCGACGAGCCGACCAATAACCTCGACATCAACTCGATCCGCTGGCTCGAGGACACGCT
GAACAACTACGATTCGACGATGATCATCATCTCGCATGATCGTCACTTCCTGAACTCGGTGTGCACGCACATGGCCGACA
TGGACTACGGCACGCTGAAGGTCTGGCCGGGCAACTACGACGACTACATGCTCGCGTCCGCGCAGGCGCGCGAGCGCCAG
GCCGCGGCGAATGCGCGCGCGAAGGAGCGCGTGGCCGAGCTGCAGGACTTCGTGCGCCGCTTCTCGGCGAACAAGTCGAA
GGCCCGCCAGGCGACGAGCCGCGCGAAGCAGATCGACAAGATCAAGATCGAGGAATTCAAGCCGTCGTCGCGCCAGAATC
CGTTCATCCGTTTCGAATTCGAGAAGAAGCTGCACAACATCGCGGTCGTCGCCGATTCGATCACGAAGAAGTACGAGCGC
ACGATCTTCGAGAATTTCAATTTGTCGGTGCAGCCCGGCGAGCGCATCGCGATCATCGGCGAGAACGGCGCGGGCAAGAC
GACGCTGCTGCGCGCGCTGTTCGGCAACCTGACGCTCGATCACGGCACGGTGAAGTGGGCCGAGAACGCGAACGTCGGCT
ACATGCCGCAGGACACGTACGAAGAGTTTCCGAACGACGTCACGCTGATGGATTGGATCGACCAGTACCGCAAGGACGGC
GACGACGAGACGATGGTGCGCGGCACGCTCGGCCGCCTGCTGTTCTCGGCGGACGACATCAAGAAATCGGTGAAGGTGCT
CTCCGGCGGGGAGAAGGGCCGGATGATCTGGGGCAAGCTGATGCTCGGCCGTCACAACGTGCTGCTGATGGACGAGCCGA
CCAACCACATGGACATGGAATCGATCGAGTCGCTGCAGATCGCGCTCGAGAAGTTCGAAGGCACGCTGATCTTCGTGTCG
CACGACCGCGAATTCGTGAGCGGGCTCGCGAACCGGATCATCGAAGTGACGACGGAGGGCAAGCTCGTCGATTTCGGCGG
GAATTACGAGGATTTCCTCGCAAGCAAGGGCTTGCAGTAA

Upstream 100 bases:

>100_bases
GTCGTCTCGACCGCCGCGGCGAGCGAGCGCGCCGCGCGGCGGCCCGATCCGCCGGGCAGGGGCTGGGCAGGCCGGCATCG
CACGAATCCGACTGCCGCGC

Downstream 100 bases:

>100_bases
GCAAGCCCTTGCCGGCGCCCCGGTCGAGGCCGGGACGCCGGCCGTCCGGTTCGGCTTTGCGCGACGCGGCGAGCGGCCGT
CCTCGATCGCGATGGGTCGA

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 599; Mature: 599

Protein sequence:

>599_residues
MRGMPPNGTRKPRTRRPIDLAPFLRFRSRPEKSAWPVRFRGPKRMRRSDSSTPAKIPGFPSIYLLTGSAVLSTANITMQF
GPKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVALEPNVRLGKLRQDQFAYEDVRVLDVVMMGHTE
MWAAMTERDAIYANPEATDDDYMHAAELEAKFAEYGGYDAEARAGALLLGIGIEEKFHSGPMRDVAPGWKLRVLLAQALF
SNPDVLLLDEPTNNLDINSIRWLEDTLNNYDSTMIIISHDRHFLNSVCTHMADMDYGTLKVWPGNYDDYMLASAQARERQ
AAANARAKERVAELQDFVRRFSANKSKARQATSRAKQIDKIKIEEFKPSSRQNPFIRFEFEKKLHNIAVVADSITKKYER
TIFENFNLSVQPGERIAIIGENGAGKTTLLRALFGNLTLDHGTVKWAENANVGYMPQDTYEEFPNDVTLMDWIDQYRKDG
DDETMVRGTLGRLLFSADDIKKSVKVLSGGEKGRMIWGKLMLGRHNVLLMDEPTNHMDMESIESLQIALEKFEGTLIFVS
HDREFVSGLANRIIEVTTEGKLVDFGGNYEDFLASKGLQ

Sequences:

>Translated_599_residues
MRGMPPNGTRKPRTRRPIDLAPFLRFRSRPEKSAWPVRFRGPKRMRRSDSSTPAKIPGFPSIYLLTGSAVLSTANITMQF
GPKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVALEPNVRLGKLRQDQFAYEDVRVLDVVMMGHTE
MWAAMTERDAIYANPEATDDDYMHAAELEAKFAEYGGYDAEARAGALLLGIGIEEKFHSGPMRDVAPGWKLRVLLAQALF
SNPDVLLLDEPTNNLDINSIRWLEDTLNNYDSTMIIISHDRHFLNSVCTHMADMDYGTLKVWPGNYDDYMLASAQARERQ
AAANARAKERVAELQDFVRRFSANKSKARQATSRAKQIDKIKIEEFKPSSRQNPFIRFEFEKKLHNIAVVADSITKKYER
TIFENFNLSVQPGERIAIIGENGAGKTTLLRALFGNLTLDHGTVKWAENANVGYMPQDTYEEFPNDVTLMDWIDQYRKDG
DDETMVRGTLGRLLFSADDIKKSVKVLSGGEKGRMIWGKLMLGRHNVLLMDEPTNHMDMESIESLQIALEKFEGTLIFVS
HDREFVSGLANRIIEVTTEGKLVDFGGNYEDFLASKGLQ
>Mature_599_residues
MRGMPPNGTRKPRTRRPIDLAPFLRFRSRPEKSAWPVRFRGPKRMRRSDSSTPAKIPGFPSIYLLTGSAVLSTANITMQF
GPKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVALEPNVRLGKLRQDQFAYEDVRVLDVVMMGHTE
MWAAMTERDAIYANPEATDDDYMHAAELEAKFAEYGGYDAEARAGALLLGIGIEEKFHSGPMRDVAPGWKLRVLLAQALF
SNPDVLLLDEPTNNLDINSIRWLEDTLNNYDSTMIIISHDRHFLNSVCTHMADMDYGTLKVWPGNYDDYMLASAQARERQ
AAANARAKERVAELQDFVRRFSANKSKARQATSRAKQIDKIKIEEFKPSSRQNPFIRFEFEKKLHNIAVVADSITKKYER
TIFENFNLSVQPGERIAIIGENGAGKTTLLRALFGNLTLDHGTVKWAENANVGYMPQDTYEEFPNDVTLMDWIDQYRKDG
DDETMVRGTLGRLLFSADDIKKSVKVLSGGEKGRMIWGKLMLGRHNVLLMDEPTNHMDMESIESLQIALEKFEGTLIFVS
HDREFVSGLANRIIEVTTEGKLVDFGGNYEDFLASKGLQ

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=533, Percent_Identity=32.0825515947467, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI10947137, Length=539, Percent_Identity=29.3135435992579, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI27881506, Length=539, Percent_Identity=29.3135435992579, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI10947135, Length=546, Percent_Identity=27.4725274725275, Blast_Score=196, Evalue=6e-50,
Organism=Homo sapiens, GI69354671, Length=546, Percent_Identity=27.4725274725275, Blast_Score=196, Evalue=6e-50,
Organism=Homo sapiens, GI153792144, Length=309, Percent_Identity=23.6245954692557, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1787041, Length=531, Percent_Identity=66.4783427495292, Blast_Score=743, Evalue=0.0,
Organism=Escherichia coli, GI1789751, Length=523, Percent_Identity=31.9311663479924, Blast_Score=278, Evalue=6e-76,
Organism=Escherichia coli, GI1787182, Length=546, Percent_Identity=30.7692307692308, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI2367384, Length=527, Percent_Identity=29.9810246679317, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1788165, Length=186, Percent_Identity=27.9569892473118, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788225, Length=230, Percent_Identity=26.9565217391304, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789672, Length=235, Percent_Identity=25.1063829787234, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790467, Length=222, Percent_Identity=24.3243243243243, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1786803, Length=222, Percent_Identity=29.2792792792793, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788644, Length=242, Percent_Identity=24.3801652892562, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1789864, Length=233, Percent_Identity=23.6051502145923, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081791, Length=212, Percent_Identity=25.9433962264151, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=565, Percent_Identity=29.2035398230088, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17555318, Length=518, Percent_Identity=28.7644787644788, Blast_Score=232, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI17559834, Length=552, Percent_Identity=27.8985507246377, Blast_Score=218, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI115533592, Length=240, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320874, Length=525, Percent_Identity=30.6666666666667, Blast_Score=251, Evalue=3e-67,
Organism=Saccharomyces cerevisiae, GI6321121, Length=558, Percent_Identity=29.3906810035842, Blast_Score=219, Evalue=9e-58,
Organism=Saccharomyces cerevisiae, GI6323278, Length=421, Percent_Identity=24.4655581947743, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6324314, Length=425, Percent_Identity=24.9411764705882, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6325030, Length=389, Percent_Identity=26.2210796915167, Blast_Score=120, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24666836, Length=522, Percent_Identity=31.2260536398467, Blast_Score=263, Evalue=4e-70,
Organism=Drosophila melanogaster, GI24642252, Length=534, Percent_Identity=27.9026217228464, Blast_Score=245, Evalue=7e-65,
Organism=Drosophila melanogaster, GI18859989, Length=534, Percent_Identity=27.9026217228464, Blast_Score=245, Evalue=7e-65,
Organism=Drosophila melanogaster, GI24641342, Length=561, Percent_Identity=28.8770053475936, Blast_Score=226, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 67391; Mature: 67391

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGMPPNGTRKPRTRRPIDLAPFLRFRSRPEKSAWPVRFRGPKRMRRSDSSTPAKIPGFP
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEECCHHHHHCCCCCCCCCCCCCC
SIYLLTGSAVLSTANITMQFGPKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGGDL
EEEEEECCHHEEEEEEEEEECCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHCCCC
EPSAGNVALEPNVRLGKLRQDQFAYEDVRVLDVVMMGHTEMWAAMTERDAIYANPEATDD
CCCCCCEEECCCCCCCCCCHHHHHHHHHHEEHHHHHCCHHHHHHHHCCCCEEECCCCCCC
DYMHAAELEAKFAEYGGYDAEARAGALLLGIGIEEKFHSGPMRDVAPGWKLRVLLAQALF
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHH
SNPDVLLLDEPTNNLDINSIRWLEDTLNNYDSTMIIISHDRHFLNSVCTHMADMDYGTLK
CCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEE
VWPGNYDDYMLASAQARERQAAANARAKERVAELQDFVRRFSANKSKARQATSRAKQIDK
ECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
IKIEEFKPSSRQNPFIRFEFEKKLHNIAVVADSITKKYERTIFENFNLSVQPGERIAIIG
EEEECCCCCCCCCCEEEEEHHHHHHHEEEEHHHHHHHHHHHHHHCCCEEECCCCEEEEEE
ENGAGKTTLLRALFGNLTLDHGTVKWAENANVGYMPQDTYEEFPNDVTLMDWIDQYRKDG
CCCCCHHHHHHHHHCCCEECCCEEEEECCCCCCCCCCHHHHHCCCCEEHHHHHHHHHHCC
DDETMVRGTLGRLLFSADDIKKSVKVLSGGEKGRMIWGKLMLGRHNVLLMDEPTNHMDME
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEECCCCCCCHH
SIESLQIALEKFEGTLIFVSHDREFVSGLANRIIEVTTEGKLVDFGGNYEDFLASKGLQ
HHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHEEEEECCCEEEECCCCHHHHHHHCCCC
>Mature Secondary Structure
MRGMPPNGTRKPRTRRPIDLAPFLRFRSRPEKSAWPVRFRGPKRMRRSDSSTPAKIPGFP
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEECCHHHHHCCCCCCCCCCCCCC
SIYLLTGSAVLSTANITMQFGPKPLFENISVKFGEGNRYGLIGANGCGKSTFMKILGGDL
EEEEEECCHHEEEEEEEEEECCCCCCCCCEEEECCCCEEEEEECCCCCHHHHHHHHCCCC
EPSAGNVALEPNVRLGKLRQDQFAYEDVRVLDVVMMGHTEMWAAMTERDAIYANPEATDD
CCCCCCEEECCCCCCCCCCHHHHHHHHHHEEHHHHHCCHHHHHHHHCCCCEEECCCCCCC
DYMHAAELEAKFAEYGGYDAEARAGALLLGIGIEEKFHSGPMRDVAPGWKLRVLLAQALF
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHCCCCCCCCCCCHHHHHHHHHHHH
SNPDVLLLDEPTNNLDINSIRWLEDTLNNYDSTMIIISHDRHFLNSVCTHMADMDYGTLK
CCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCEEE
VWPGNYDDYMLASAQARERQAAANARAKERVAELQDFVRRFSANKSKARQATSRAKQIDK
ECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
IKIEEFKPSSRQNPFIRFEFEKKLHNIAVVADSITKKYERTIFENFNLSVQPGERIAIIG
EEEECCCCCCCCCCEEEEEHHHHHHHEEEEHHHHHHHHHHHHHHCCCEEECCCCEEEEEE
ENGAGKTTLLRALFGNLTLDHGTVKWAENANVGYMPQDTYEEFPNDVTLMDWIDQYRKDG
CCCCCHHHHHHHHHCCCEECCCEEEEECCCCCCCCCCHHHHHCCCCEEHHHHHHHHHHCC
DDETMVRGTLGRLLFSADDIKKSVKVLSGGEKGRMIWGKLMLGRHNVLLMDEPTNHMDME
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEECCCCCCCHH
SIESLQIALEKFEGTLIFVSHDREFVSGLANRIIEVTTEGKLVDFGGNYEDFLASKGLQ
HHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHEEEEECCCEEEECCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]