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The map label for this gene is cysC_1 [H]

Identifier: 237812360

GI number: 237812360

Start: 2071542

End: 2072147

Strand: Reverse

Name: cysC_1 [H]

Synonym: GBP346_A2108

Alternate gene names: 237812360

Gene position: 2072147-2071542 (Counterclockwise)

Preceding gene: 237812362

Following gene: 237812359

Centisome position: 50.56

GC content: 61.06

Gene sequence:

>606_bases
ATGGACAAGTTACATGCGGAGCGCAACGCCGAATGGCAGACGACGTCCGTCAGCCGGCGTGATCGTGAGTCGCGGCAGGC
GCACGGCGCGCTTGCAGTCTGGCTAACGGGCCTTCCCGGAGCTGGAAAGTCGACACTGGCGATCGAGGCGGAACGATGCC
TCCATCAAGCCGGGAAGCGGACTTATGTTCTGGATGGTGACAATCTTCGGCACGGACTGTGTCGCGACCTGGGATTCTCC
GCGGACGATCGCGCGGAAAACATTCGCCGCGCGGGCGAAGTGGCGCGACTGTTCGTCGATGCTGGCGTCATTGTGCTGTC
GGCCTTCATTTCTCCATTCCGATTCGATCGTGCGAAGGTTCGTGCACTGTTCGACGCGGGCGACTTCATCGAAGTGTACT
GCGACTGCGATCCGCGGATTTGCGAAATCCGGGACGTCAAAGGCTTGTACAGAAGGGCGCGTGCGGGGCTGATTTCCGAG
TTCACCGGCATCTCCTCTCCTTACGAGCCGCCGCGGCATCCTGACGTCTACGTCAATACTGGCAAGGAATCGCTGGATGC
ATGCGTCGACAGGATCGTCCGCCGCGTGCTCCATTCGCTGCGCTAG

Upstream 100 bases:

>100_bases
ATGCCATAAGGTGCAAAACATTGCCGTTGCCGCGGCGCTTGACGGCGGTCAAGCACCGCCATCGGCGCACGGCGCCGGGC
AATTCACTGACAGGAAGCTT

Downstream 100 bases:

>100_bases
TTATGATTAAGTTAGCTAAGCTGATGTGGCCGGGAGATCTGAGGAAGGCCACTTTGCAGCCGGTCCAGGATGAACAGCGT
GTGCTCGATGCGGCCAATCG

Product: adenylyl-sulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MDKLHAERNAEWQTTSVSRRDRESRQAHGALAVWLTGLPGAGKSTLAIEAERCLHQAGKRTYVLDGDNLRHGLCRDLGFS
ADDRAENIRRAGEVARLFVDAGVIVLSAFISPFRFDRAKVRALFDAGDFIEVYCDCDPRICEIRDVKGLYRRARAGLISE
FTGISSPYEPPRHPDVYVNTGKESLDACVDRIVRRVLHSLR

Sequences:

>Translated_201_residues
MDKLHAERNAEWQTTSVSRRDRESRQAHGALAVWLTGLPGAGKSTLAIEAERCLHQAGKRTYVLDGDNLRHGLCRDLGFS
ADDRAENIRRAGEVARLFVDAGVIVLSAFISPFRFDRAKVRALFDAGDFIEVYCDCDPRICEIRDVKGLYRRARAGLISE
FTGISSPYEPPRHPDVYVNTGKESLDACVDRIVRRVLHSLR
>Mature_201_residues
MDKLHAERNAEWQTTSVSRRDRESRQAHGALAVWLTGLPGAGKSTLAIEAERCLHQAGKRTYVLDGDNLRHGLCRDLGFS
ADDRAENIRRAGEVARLFVDAGVIVLSAFISPFRFDRAKVRALFDAGDFIEVYCDCDPRICEIRDVKGLYRRARAGLISE
FTGISSPYEPPRHPDVYVNTGKESLDACVDRIVRRVLHSLR

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=191, Percent_Identity=45.0261780104712, Blast_Score=168, Evalue=2e-42,
Organism=Homo sapiens, GI34447231, Length=191, Percent_Identity=47.1204188481675, Blast_Score=168, Evalue=3e-42,
Organism=Homo sapiens, GI62912492, Length=191, Percent_Identity=47.1204188481675, Blast_Score=168, Evalue=3e-42,
Organism=Escherichia coli, GI1789107, Length=198, Percent_Identity=50, Blast_Score=191, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17542422, Length=191, Percent_Identity=45.5497382198953, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6322852, Length=191, Percent_Identity=43.455497382199, Blast_Score=167, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24667032, Length=164, Percent_Identity=49.390243902439, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24667028, Length=164, Percent_Identity=49.390243902439, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24667036, Length=164, Percent_Identity=49.390243902439, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI116007838, Length=164, Percent_Identity=49.390243902439, Blast_Score=161, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24667044, Length=164, Percent_Identity=49.390243902439, Blast_Score=161, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24667040, Length=164, Percent_Identity=49.390243902439, Blast_Score=161, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 22570; Mature: 22570

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLHAERNAEWQTTSVSRRDRESRQAHGALAVWLTGLPGAGKSTLAIEAERCLHQAGKR
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCEEEHHHHHHHHCCCE
TYVLDGDNLRHGLCRDLGFSADDRAENIRRAGEVARLFVDAGVIVLSAFISPFRFDRAKV
EEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RALFDAGDFIEVYCDCDPRICEIRDVKGLYRRARAGLISEFTGISSPYEPPRHPDVYVNT
HHHHCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEC
GKESLDACVDRIVRRVLHSLR
CHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDKLHAERNAEWQTTSVSRRDRESRQAHGALAVWLTGLPGAGKSTLAIEAERCLHQAGKR
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCEEEHHHHHHHHCCCE
TYVLDGDNLRHGLCRDLGFSADDRAENIRRAGEVARLFVDAGVIVLSAFISPFRFDRAKV
EEEECCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
RALFDAGDFIEVYCDCDPRICEIRDVKGLYRRARAGLISEFTGISSPYEPPRHPDVYVNT
HHHHCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEC
GKESLDACVDRIVRRVLHSLR
CHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917486 [H]