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The map label for this gene is allB [H]

Identifier: 237812344

GI number: 237812344

Start: 2055455

End: 2056840

Strand: Reverse

Name: allB [H]

Synonym: GBP346_A2092

Alternate gene names: 237812344

Gene position: 2056840-2055455 (Counterclockwise)

Preceding gene: 237812352

Following gene: 237812343

Centisome position: 50.18

GC content: 69.19

Gene sequence:

>1386_bases
ATGAGTGATTTCGAGCAGGTGGTGCGCGGCCGGCTGGTTGACGCGCAGCAGATTGTCGAGGACGGCTGGCTCGCAATTCG
GGGCGGCCGGATCGCGGCGCGCGGCGCGGGGGCGCCTCCGGCGGCGCGCGACTTGATCGACGCGCGCGGGCAGTGGGTGC
TGCCGGGTGTCGTCGACGGCCAGGTGCACGCGGGCAGCCAGGCGAACCACGAAGGGCTCGGGCGTGCGTCGCGCGCGGCG
GCGGCGGGCGGAGTGACCGTGATGGTCGACATGCCGTACGACGATCCGGAACCTGTCGCGTCGCGGGCGCAGCTCGATCG
CAAGATCGCGGAAGCCGAGCGCGATTGCCACGTCGACATCGCGCTGTACGGCACGCTCAACGCAAAGCACGGCCTCGACG
CGGCGGCCGGGCTGATCGACGGCGGCGTCTGCGCGTTCAAGTTCTCGATGTTCGAGGCGACGCCCGGCCGGTTCCCGCGT
GTCGACGAGGACGTGTTGTACGACGCATTCCGGCTGGTCGCCCCGTCGGGCCTCGCGTGCGGCGTGCACAACCAGATGCA
GGACCTCACGCGCAAGAATATCGCGCGGATGATCGAGGCCGGCGACACGGGCTGGGATGCGTTCCTGCGCGCGCATCCAC
CGCTGATCGAGAACCTGGCGACCGCGCTGATCTACGAGATCGGCGCGGAGACGGGCGCCCGCGCGCACGCGGTGCACGTG
TCGACGTCGCGCGGCTTCGAGCTGTGCAACATGTTCCGGCGCGCCGGCCATCACGCGAGCATCGAAACCTGCGTGCAGTA
CCTGATGCTCGATCACGAAACGCATACGAAACGCTTCGGCGCGAAGACGAAGCACTACCCGCCGATTCGCCCGCGCGCGG
AGCAGGAATTGCTGTGGACGCATGTCGCGCGCGGCGAGTGCACGTTCGTGTCGTCGGATCACGTGAGCTGGGAGCTCAAA
CGCAAGGGGGACGCCAACGTGTTCCGCAACGCGTCGGGCGGTCCGGGGCTCGAAACGTTGCTGCCGGCGTTCTGGACCGG
CTGCGAGCAGCATGGCATCGCGCCGACGCGGGTCGCCGAGCTGCTGGCGACGAATCCGGCGCGGCACTTCCTGCTCGACG
ATCGCAAGGGGTCGCTCGACGTCGGCGCCGACGCGGATTTCGTGATCCTCACGCCCGAACGCTACGCGTTCGATCCGTCG
TGCAGCCTGTCGGCCGTGCAGTGGAGCGCGTTCGAGGGCATGGAATTCGCGGTGCGCATCGCCGCCACATATTGTCGCGG
CGCGCTCGTGTACGACGGCGCACGCATCGTCAATCCGGCGGGCTCGGGCCGCTTCCTGAAGCCGCATGGCAGCCAGCCGA
TCGTCACGCAACCGGAGCGCGCATGA

Upstream 100 bases:

>100_bases
CAGCCTTAACTCCGTGTTATGTCGAGACGATAAATCGGCATAGGACATTCTGGCAGAGCGCTGCCTAAACTGCTCGTGAT
CAAAAATGCAGGAGACTGAA

Downstream 100 bases:

>100_bases
ATCCGACGGTCTTTCCGCCCCTGAATGCCGAGCGCCTGAATGCGCGCGTCGAGCAACTCGCGCGTTTCACGCGAGCCGAC
GTTCCGTGGACGCGCCGCGC

Product: amidohydrolase

Products: NA

Alternate protein names: Allantoin-utilizing enzyme [H]

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MSDFEQVVRGRLVDAQQIVEDGWLAIRGGRIAARGAGAPPAARDLIDARGQWVLPGVVDGQVHAGSQANHEGLGRASRAA
AAGGVTVMVDMPYDDPEPVASRAQLDRKIAEAERDCHVDIALYGTLNAKHGLDAAAGLIDGGVCAFKFSMFEATPGRFPR
VDEDVLYDAFRLVAPSGLACGVHNQMQDLTRKNIARMIEAGDTGWDAFLRAHPPLIENLATALIYEIGAETGARAHAVHV
STSRGFELCNMFRRAGHHASIETCVQYLMLDHETHTKRFGAKTKHYPPIRPRAEQELLWTHVARGECTFVSSDHVSWELK
RKGDANVFRNASGGPGLETLLPAFWTGCEQHGIAPTRVAELLATNPARHFLLDDRKGSLDVGADADFVILTPERYAFDPS
CSLSAVQWSAFEGMEFAVRIAATYCRGALVYDGARIVNPAGSGRFLKPHGSQPIVTQPERA

Sequences:

>Translated_461_residues
MSDFEQVVRGRLVDAQQIVEDGWLAIRGGRIAARGAGAPPAARDLIDARGQWVLPGVVDGQVHAGSQANHEGLGRASRAA
AAGGVTVMVDMPYDDPEPVASRAQLDRKIAEAERDCHVDIALYGTLNAKHGLDAAAGLIDGGVCAFKFSMFEATPGRFPR
VDEDVLYDAFRLVAPSGLACGVHNQMQDLTRKNIARMIEAGDTGWDAFLRAHPPLIENLATALIYEIGAETGARAHAVHV
STSRGFELCNMFRRAGHHASIETCVQYLMLDHETHTKRFGAKTKHYPPIRPRAEQELLWTHVARGECTFVSSDHVSWELK
RKGDANVFRNASGGPGLETLLPAFWTGCEQHGIAPTRVAELLATNPARHFLLDDRKGSLDVGADADFVILTPERYAFDPS
CSLSAVQWSAFEGMEFAVRIAATYCRGALVYDGARIVNPAGSGRFLKPHGSQPIVTQPERA
>Mature_460_residues
SDFEQVVRGRLVDAQQIVEDGWLAIRGGRIAARGAGAPPAARDLIDARGQWVLPGVVDGQVHAGSQANHEGLGRASRAAA
AGGVTVMVDMPYDDPEPVASRAQLDRKIAEAERDCHVDIALYGTLNAKHGLDAAAGLIDGGVCAFKFSMFEATPGRFPRV
DEDVLYDAFRLVAPSGLACGVHNQMQDLTRKNIARMIEAGDTGWDAFLRAHPPLIENLATALIYEIGAETGARAHAVHVS
TSRGFELCNMFRRAGHHASIETCVQYLMLDHETHTKRFGAKTKHYPPIRPRAEQELLWTHVARGECTFVSSDHVSWELKR
KGDANVFRNASGGPGLETLLPAFWTGCEQHGIAPTRVAELLATNPARHFLLDDRKGSLDVGADADFVILTPERYAFDPSC
SLSAVQWSAFEGMEFAVRIAATYCRGALVYDGARIVNPAGSGRFLKPHGSQPIVTQPERA

Specific function: Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring [H]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Allantoinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503379, Length=470, Percent_Identity=24.6808510638298, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI4503375, Length=460, Percent_Identity=26.5217391304348, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI4503051, Length=472, Percent_Identity=25.2118644067797, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI62422571, Length=472, Percent_Identity=25.2118644067797, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI4503377, Length=474, Percent_Identity=24.8945147679325, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI190194363, Length=463, Percent_Identity=25.2699784017279, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI18105007, Length=444, Percent_Identity=23.6486486486486, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI19923821, Length=423, Percent_Identity=23.1678486997636, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1786722, Length=436, Percent_Identity=27.7522935779816, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87082175, Length=444, Percent_Identity=27.9279279279279, Blast_Score=135, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI71989490, Length=430, Percent_Identity=23.953488372093, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17539558, Length=458, Percent_Identity=22.4890829694323, Blast_Score=79, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322218, Length=402, Percent_Identity=26.1194029850746, Blast_Score=121, Evalue=3e-28,
Organism=Drosophila melanogaster, GI18859883, Length=401, Percent_Identity=28.428927680798, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI221377917, Length=482, Percent_Identity=23.6514522821577, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17137462, Length=433, Percent_Identity=23.7875288683603, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017593
- InterPro:   IPR006680
- InterPro:   IPR004722
- InterPro:   IPR002195
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.5 [H]

Molecular weight: Translated: 49976; Mature: 49845

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS01037 SBP_BACTERIAL_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFEQVVRGRLVDAQQIVEDGWLAIRGGRIAARGAGAPPAARDLIDARGQWVLPGVVDG
CCHHHHHHHHHCCCHHHHHHCCCEEEECCEEEECCCCCCHHHHHHHHCCCCEEECCEECC
QVHAGSQANHEGLGRASRAAAAGGVTVMVDMPYDDPEPVASRAQLDRKIAEAERDCHVDI
CEECCCCCCCHHCCHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
ALYGTLNAKHGLDAAAGLIDGGVCAFKFSMFEATPGRFPRVDEDVLYDAFRLVAPSGLAC
EEEEECCCCCCCHHHHHHHCCCEEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEE
GVHNQMQDLTRKNIARMIEAGDTGWDAFLRAHPPLIENLATALIYEIGAETGARAHAVHV
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEE
STSRGFELCNMFRRAGHHASIETCVQYLMLDHETHTKRFGAKTKHYPPIRPRAEQELLWT
ECCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHHHHHH
HVARGECTFVSSDHVSWELKRKGDANVFRNASGGPGLETLLPAFWTGCEQHGIAPTRVAE
HHCCCEEEEEECCCCEEEEECCCCCCCEECCCCCCCHHHHHHHHHCCHHHCCCCHHHHHH
LLATNPARHFLLDDRKGSLDVGADADFVILTPERYAFDPSCSLSAVQWSAFEGMEFAVRI
HHHCCCCCEEEEECCCCCEECCCCCCEEEECCCCCCCCCCCCCEEEEECHHCCCHHHHHH
AATYCRGALVYDGARIVNPAGSGRFLKPHGSQPIVTQPERA
HHHHHCCEEEECCCEEECCCCCCCEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDFEQVVRGRLVDAQQIVEDGWLAIRGGRIAARGAGAPPAARDLIDARGQWVLPGVVDG
CHHHHHHHHHCCCHHHHHHCCCEEEECCEEEECCCCCCHHHHHHHHCCCCEEECCEECC
QVHAGSQANHEGLGRASRAAAAGGVTVMVDMPYDDPEPVASRAQLDRKIAEAERDCHVDI
CEECCCCCCCHHCCHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEE
ALYGTLNAKHGLDAAAGLIDGGVCAFKFSMFEATPGRFPRVDEDVLYDAFRLVAPSGLAC
EEEEECCCCCCCHHHHHHHCCCEEEEEEEHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEE
GVHNQMQDLTRKNIARMIEAGDTGWDAFLRAHPPLIENLATALIYEIGAETGARAHAVHV
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEE
STSRGFELCNMFRRAGHHASIETCVQYLMLDHETHTKRFGAKTKHYPPIRPRAEQELLWT
ECCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHHHHHH
HVARGECTFVSSDHVSWELKRKGDANVFRNASGGPGLETLLPAFWTGCEQHGIAPTRVAE
HHCCCEEEEEECCCCEEEEECCCCCCCEECCCCCCCHHHHHHHHHCCHHHCCCCHHHHHH
LLATNPARHFLLDDRKGSLDVGADADFVILTPERYAFDPSCSLSAVQWSAFEGMEFAVRI
HHHCCCCCEEEEECCCCCEECCCCCCEEEECCCCCCCCCCCCCEEEEECHHCCCHHHHHH
AATYCRGALVYDGARIVNPAGSGRFLKPHGSQPIVTQPERA
HHHHHCCEEEECCCEEECCCCCCCEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA