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The map label for this gene is quiP [H]

Identifier: 237812306

GI number: 237812306

Start: 2022336

End: 2024708

Strand: Direct

Name: quiP [H]

Synonym: GBP346_A2054

Alternate gene names: 237812306

Gene position: 2022336-2024708 (Clockwise)

Preceding gene: 237812305

Following gene: 237812315

Centisome position: 49.34

GC content: 73.62

Gene sequence:

>2373_bases
ATGGCATCTCGCACGAACCGCTTGCCGCGGTGGCTCAAGATCCTGCCCGGCGTCATTCTTCTCGGCGCGCTGCTCGTCGC
GGCCGGCGCGGCGCTGTTCCTGCGCGCGAGCCTGCCGCGGCTCGACGGCGACGTGCGCGCGCCGACGCTCGGCGGCCCGA
TGACGATCGAACGCGACGCCGCGGGCGTGCCGACCGTCGCCGCGCGCGACCGCTTCGACGCCGCCTACGGCATCGGCTAC
CTGCATGCGCAGGACCGCTTCTTCCAGATGGATTATCTGCGCCGGACCGGAGCAGGGGAGTTGGCGGAGCTGCTCGGGCC
CGCCGCGCTGGATTTCGATCGCGAGCACCGGCTGTTCCGGTTTCGCGCGCGCGCCGCGGCGGCGTTCGCGCAGTTGCCGC
CCGACGAGCGGCGCCTGCTCGAACGCTACACGCAAGGCGTGAACGACGGCCTCGCCGCGCTGCGCGCCCGGCCGTTCGAA
TACGCGCTGCTCGGCGAGCCGCCGGCGCGGTGGCGGCCCGAAGATTCGCTGCTCGTGATCTGGGCGATGTACTTTCAGGT
GCAGGGCACGCTCGCGTCGCGCGACATCGCGCGCAACTGGCTGACGGCGCACGCGACGCAGCAGCAGCGCGCCTTCCTGC
TGCCGTCGTCGAGCGGATTCGACGCGCCGCTCGATGCGCCGCGCATCGACGAAGCGCCCGCGCCGCTGCCCGACGCCGCG
CCCGACTGGTTCCGCGCCGCAGGCGACGGCGCGGCCAAGCGCGCATCGCTCGATTTCCGCTCGTCGGTCGGCAGCAACAA
CTGGGCCATTGCCGGCAGCCGCAGCGCACGCGGCGCGGCCATCGTCGGCGACGACATGCACCTCGTGCTCGGCCTGCCGA
ACACCTGGTATCGCGCGGCCTTCACCTATCCGGGCGGCGCGGCGCCCGTGCGGCGGGCCGTCGGCGTGACGCTCGCCGGG
CTGCCGGCGATCGTGGCCGGCAGCAACGGGCATGTCGCATGGGGCTTGACGGTCGGTTACGCGGATTGCCTCGACCTCGT
GCCGCTCGAGCGCGACGGCGACGATTCGCGGGCGTTCCGGATGGGCGGCGCGCGCCAGGTCGCGCGCCGGTACGTCGAAT
CGATCCGGGTGCGCGGCGGCGCGTCCGTTTCGCTGACCGTACTGGAAACGACGGTCGGGCCGGTGCGGGAAATCGGCGGC
CGGCCCTATGCGGTCCACTGGGTCGCGCAGTTGCCGGGCGCGGTGAACCTGGGGCTCGCGCGCCTCGCGGACGCCGTCGA
CGTCGACGGCGCGATGCGCGTGGCGAATACGCTCGGCATTCCGGCCGAGAACATCGTGGTCGGCGACCGCGCCGGGCGAA
TCGGCTGGACCATCGCCGGCGCGCTGCCGGACCGGCGCGCGCCGCGCGGCGGCGAGGGCGCGGCGTGGCGGTCGCTGCTG
CCGCCCGACGCGTATCCGCGCGTCGTCGATCCGTCCGGCGGCCAGCTCTGGACCGCGAACAGCCGCCAGTTGGCGGGCGA
CGCATACCGGTTGATCGGCGATGGCGGCACGGATCTCGGCGCGCGGGCGACCCAGTTGCGCGACGGACTGACGGCGCTCG
GCCGCACCGACGAACAAGCGGCGTATCGGATCGACCTCGACGATCGCGCGCTGTTCATCGCCCAGTGGCGCGACCGCGCG
CTGCGCGTGCTCGACGACGCGGCGCTCGCGGGCCACCCGTCGCGCGCGGAATTCCGCCGGCTGCTCGAGCACGGCTGGAC
GGGCCGGGCGAGCGTCGACTCGGTCGGGTACACGCTCGCGCGCGGCTTTCTGTATCGGCTGTACGACGTCACGTTCGACG
GGCTGAACGCACGCCTGAAGCAAGTCGATGCGGGCGCGGACTACGAGCTGGCGAATCTGCGCTGGCCGGCCGTCGTCGCG
CGGCTGCTCGACGCGCAGCCGCCGGGCTGGCTGCCGGCCGGCGCGTCGAGCTGGCGCGACGTGCAACTGATCGCGATCGA
CCGGACCATCGCCGCGCTCACGGCCGACGGCGCGCCGCTCGCGCGGGCGAGCTGGGGCGCGCGCAACACGCTGCGGATCG
CGCATCCGTTCGCCGGCAGCCTGCCGCTGCTCGGCGGATGGCTGACGGCGCCGGCCGTGCAGATGCCGGGTGATTCGCAC
ATGCCGCGCGTCGCCGCGCCGGATTTCGGGCAATCCGAGCGGATGGTCGTGTCGCCGGGGCACGAGGAATTCGGGATCTT
CAACATGCCGGGCGGGCAGAGCGGGCATCCGCTGAGCCCGTTTTTCCTCGCGGGCCACGATGCGTGGGTGCGCGCGGAGC
CGACGCCGTTCTTGCCCGGCGTCGCGCGGCATACGTTGAGATTCGCGCCGTAG

Upstream 100 bases:

>100_bases
CCCGCCGCCTGCCTCGGAGCGCCGCGTGCCGCCGCGCTCCGGAGGCGGGCGGCGCGGCGCCAACCCGTCTCCCCGTCCCG
TCTCAGGAAATCGCGTACTC

Downstream 100 bases:

>100_bases
CCGTGATCTTGGTCGTGACCGTGACCGCGGCGAACGCGTGAAGCGCTTCGGTGCGGTTTCGCTTCCGGATGCGGGCGCCG
TGCTCAGCCCGAGTCGCTCG

Product: family S45 unassigned peptidase

Products: NA

Alternate protein names: AHL acylase quiP; Acyl-HSL acylase quiP; Quorum signal utilization and inactivation protein; Acyl-HSL acylase quiP subunit alpha; Acyl-HSL acylase quiP subunit beta [H]

Number of amino acids: Translated: 790; Mature: 789

Protein sequence:

>790_residues
MASRTNRLPRWLKILPGVILLGALLVAAGAALFLRASLPRLDGDVRAPTLGGPMTIERDAAGVPTVAARDRFDAAYGIGY
LHAQDRFFQMDYLRRTGAGELAELLGPAALDFDREHRLFRFRARAAAAFAQLPPDERRLLERYTQGVNDGLAALRARPFE
YALLGEPPARWRPEDSLLVIWAMYFQVQGTLASRDIARNWLTAHATQQQRAFLLPSSSGFDAPLDAPRIDEAPAPLPDAA
PDWFRAAGDGAAKRASLDFRSSVGSNNWAIAGSRSARGAAIVGDDMHLVLGLPNTWYRAAFTYPGGAAPVRRAVGVTLAG
LPAIVAGSNGHVAWGLTVGYADCLDLVPLERDGDDSRAFRMGGARQVARRYVESIRVRGGASVSLTVLETTVGPVREIGG
RPYAVHWVAQLPGAVNLGLARLADAVDVDGAMRVANTLGIPAENIVVGDRAGRIGWTIAGALPDRRAPRGGEGAAWRSLL
PPDAYPRVVDPSGGQLWTANSRQLAGDAYRLIGDGGTDLGARATQLRDGLTALGRTDEQAAYRIDLDDRALFIAQWRDRA
LRVLDDAALAGHPSRAEFRRLLEHGWTGRASVDSVGYTLARGFLYRLYDVTFDGLNARLKQVDAGADYELANLRWPAVVA
RLLDAQPPGWLPAGASSWRDVQLIAIDRTIAALTADGAPLARASWGARNTLRIAHPFAGSLPLLGGWLTAPAVQMPGDSH
MPRVAAPDFGQSERMVVSPGHEEFGIFNMPGGQSGHPLSPFFLAGHDAWVRAEPTPFLPGVARHTLRFAP

Sequences:

>Translated_790_residues
MASRTNRLPRWLKILPGVILLGALLVAAGAALFLRASLPRLDGDVRAPTLGGPMTIERDAAGVPTVAARDRFDAAYGIGY
LHAQDRFFQMDYLRRTGAGELAELLGPAALDFDREHRLFRFRARAAAAFAQLPPDERRLLERYTQGVNDGLAALRARPFE
YALLGEPPARWRPEDSLLVIWAMYFQVQGTLASRDIARNWLTAHATQQQRAFLLPSSSGFDAPLDAPRIDEAPAPLPDAA
PDWFRAAGDGAAKRASLDFRSSVGSNNWAIAGSRSARGAAIVGDDMHLVLGLPNTWYRAAFTYPGGAAPVRRAVGVTLAG
LPAIVAGSNGHVAWGLTVGYADCLDLVPLERDGDDSRAFRMGGARQVARRYVESIRVRGGASVSLTVLETTVGPVREIGG
RPYAVHWVAQLPGAVNLGLARLADAVDVDGAMRVANTLGIPAENIVVGDRAGRIGWTIAGALPDRRAPRGGEGAAWRSLL
PPDAYPRVVDPSGGQLWTANSRQLAGDAYRLIGDGGTDLGARATQLRDGLTALGRTDEQAAYRIDLDDRALFIAQWRDRA
LRVLDDAALAGHPSRAEFRRLLEHGWTGRASVDSVGYTLARGFLYRLYDVTFDGLNARLKQVDAGADYELANLRWPAVVA
RLLDAQPPGWLPAGASSWRDVQLIAIDRTIAALTADGAPLARASWGARNTLRIAHPFAGSLPLLGGWLTAPAVQMPGDSH
MPRVAAPDFGQSERMVVSPGHEEFGIFNMPGGQSGHPLSPFFLAGHDAWVRAEPTPFLPGVARHTLRFAP
>Mature_789_residues
ASRTNRLPRWLKILPGVILLGALLVAAGAALFLRASLPRLDGDVRAPTLGGPMTIERDAAGVPTVAARDRFDAAYGIGYL
HAQDRFFQMDYLRRTGAGELAELLGPAALDFDREHRLFRFRARAAAAFAQLPPDERRLLERYTQGVNDGLAALRARPFEY
ALLGEPPARWRPEDSLLVIWAMYFQVQGTLASRDIARNWLTAHATQQQRAFLLPSSSGFDAPLDAPRIDEAPAPLPDAAP
DWFRAAGDGAAKRASLDFRSSVGSNNWAIAGSRSARGAAIVGDDMHLVLGLPNTWYRAAFTYPGGAAPVRRAVGVTLAGL
PAIVAGSNGHVAWGLTVGYADCLDLVPLERDGDDSRAFRMGGARQVARRYVESIRVRGGASVSLTVLETTVGPVREIGGR
PYAVHWVAQLPGAVNLGLARLADAVDVDGAMRVANTLGIPAENIVVGDRAGRIGWTIAGALPDRRAPRGGEGAAWRSLLP
PDAYPRVVDPSGGQLWTANSRQLAGDAYRLIGDGGTDLGARATQLRDGLTALGRTDEQAAYRIDLDDRALFIAQWRDRAL
RVLDDAALAGHPSRAEFRRLLEHGWTGRASVDSVGYTLARGFLYRLYDVTFDGLNARLKQVDAGADYELANLRWPAVVAR
LLDAQPPGWLPAGASSWRDVQLIAIDRTIAALTADGAPLARASWGARNTLRIAHPFAGSLPLLGGWLTAPAVQMPGDSHM
PRVAAPDFGQSERMVVSPGHEEFGIFNMPGGQSGHPLSPFFLAGHDAWVRAEPTPFLPGVARHTLRFAP

Specific function: Catalyzes the deacylation of acyl-homoserine lactone (AHL or acyl-HSL), releasing homoserine lactone (HSL) and the corresponding fatty acid. Possesses a specificity for the degradation of long-chain acyl-HSLs (side chains of seven or more carbons in lengt

COG id: COG2366

COG function: function code R; Protein related to penicillin acylase

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S45 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014395
- InterPro:   IPR002692 [H]

Pfam domain/function: PF01804 Penicil_amidase [H]

EC number: =3.5.1.97 [H]

Molecular weight: Translated: 84931; Mature: 84800

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRTNRLPRWLKILPGVILLGALLVAAGAALFLRASLPRLDGDVRAPTLGGPMTIERDA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCC
AGVPTVAARDRFDAAYGIGYLHAQDRFFQMDYLRRTGAGELAELLGPAALDFDREHRLFR
CCCCCHHHCCCCCHHHCEEEEECCCHHHHHHHHHHCCCHHHHHHHCCHHCCCCCHHHHHH
FRARAAAAFAQLPPDERRLLERYTQGVNDGLAALRARPFEYALLGEPPARWRPEDSLLVI
HHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEE
WAMYFQVQGTLASRDIARNWLTAHATQQQRAFLLPSSSGFDAPLDAPRIDEAPAPLPDAA
EEEEHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
PDWFRAAGDGAAKRASLDFRSSVGSNNWAIAGSRSARGAAIVGDDMHLVLGLPNTWYRAA
CHHHHHCCCCCHHHCCCHHHHHCCCCCEEEECCCCCCCEEEECCCEEEEEECCCCCEEEE
FTYPGGAAPVRRAVGVTLAGLPAIVAGSNGHVAWGLTVGYADCLDLVPLERDGDDSRAFR
EECCCCCHHHHHHHCCEEECCCEEEECCCCCEEEEEEECHHHHHHCCCCCCCCCCCHHHH
MGGARQVARRYVESIRVRGGASVSLTVLETTVGPVREIGGRPYAVHWVAQLPGAVNLGLA
CCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHCCCCEEEEEHHHCCCCHHHHHH
RLADAVDVDGAMRVANTLGIPAENIVVGDRAGRIGWTIAGALPDRRAPRGGEGAAWRSLL
HHHHHHCCCCHHHHHHHCCCCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCCCCHHCCC
PPDAYPRVVDPSGGQLWTANSRQLAGDAYRLIGDGGTDLGARATQLRDGLTALGRTDEQA
CCCCCCCEECCCCCEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCC
AYRIDLDDRALFIAQWRDRALRVLDDAALAGHPSRAEFRRLLEHGWTGRASVDSVGYTLA
EEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHH
RGFLYRLYDVTFDGLNARLKQVDAGADYELANLRWPAVVARLLDAQPPGWLPAGASSWRD
HHHHHHHHHHHHCCCCHHHHHHCCCCCEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
VQLIAIDRTIAALTADGAPLARASWGARNTLRIAHPFAGSLPLLGGWLTAPAVQMPGDSH
EEEEEECCEEEEEECCCCCCHHCCCCCCCEEEEECCCCCCCCCCCHHHCCCCEECCCCCC
MPRVAAPDFGQSERMVVSPGHEEFGIFNMPGGQSGHPLSPFFLAGHDAWVRAEPTPFLPG
CCCCCCCCCCCCCEEEECCCCCCCCEEECCCCCCCCCCCCEEEECCCCEEECCCCCCCCC
VARHTLRFAP
HHHHHEECCC
>Mature Secondary Structure 
ASRTNRLPRWLKILPGVILLGALLVAAGAALFLRASLPRLDGDVRAPTLGGPMTIERDA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCC
AGVPTVAARDRFDAAYGIGYLHAQDRFFQMDYLRRTGAGELAELLGPAALDFDREHRLFR
CCCCCHHHCCCCCHHHCEEEEECCCHHHHHHHHHHCCCHHHHHHHCCHHCCCCCHHHHHH
FRARAAAAFAQLPPDERRLLERYTQGVNDGLAALRARPFEYALLGEPPARWRPEDSLLVI
HHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEE
WAMYFQVQGTLASRDIARNWLTAHATQQQRAFLLPSSSGFDAPLDAPRIDEAPAPLPDAA
EEEEHHHHCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
PDWFRAAGDGAAKRASLDFRSSVGSNNWAIAGSRSARGAAIVGDDMHLVLGLPNTWYRAA
CHHHHHCCCCCHHHCCCHHHHHCCCCCEEEECCCCCCCEEEECCCEEEEEECCCCCEEEE
FTYPGGAAPVRRAVGVTLAGLPAIVAGSNGHVAWGLTVGYADCLDLVPLERDGDDSRAFR
EECCCCCHHHHHHHCCEEECCCEEEECCCCCEEEEEEECHHHHHHCCCCCCCCCCCHHHH
MGGARQVARRYVESIRVRGGASVSLTVLETTVGPVREIGGRPYAVHWVAQLPGAVNLGLA
CCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHCCCCEEEEEHHHCCCCHHHHHH
RLADAVDVDGAMRVANTLGIPAENIVVGDRAGRIGWTIAGALPDRRAPRGGEGAAWRSLL
HHHHHHCCCCHHHHHHHCCCCCCCEEECCCCCCCEEEEEECCCCCCCCCCCCCCCHHCCC
PPDAYPRVVDPSGGQLWTANSRQLAGDAYRLIGDGGTDLGARATQLRDGLTALGRTDEQA
CCCCCCCEECCCCCEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCC
AYRIDLDDRALFIAQWRDRALRVLDDAALAGHPSRAEFRRLLEHGWTGRASVDSVGYTLA
EEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHH
RGFLYRLYDVTFDGLNARLKQVDAGADYELANLRWPAVVARLLDAQPPGWLPAGASSWRD
HHHHHHHHHHHHCCCCHHHHHHCCCCCEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCC
VQLIAIDRTIAALTADGAPLARASWGARNTLRIAHPFAGSLPLLGGWLTAPAVQMPGDSH
EEEEEECCEEEEEECCCCCCHHCCCCCCCEEEEECCCCCCCCCCCHHHCCCCEECCCCCC
MPRVAAPDFGQSERMVVSPGHEEFGIFNMPGGQSGHPLSPFFLAGHDAWVRAEPTPFLPG
CCCCCCCCCCCCCEEEECCCCCCCCEEECCCCCCCCCCCCEEEECCCCEEECCCCCCCCC
VARHTLRFAP
HHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]