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The map label for this gene is yehW [H]

Identifier: 237812270

GI number: 237812270

Start: 1966872

End: 1967690

Strand: Reverse

Name: yehW [H]

Synonym: GBP346_A2018

Alternate gene names: 237812270

Gene position: 1967690-1966872 (Counterclockwise)

Preceding gene: 237812271

Following gene: 237812269

Centisome position: 48.01

GC content: 73.63

Gene sequence:

>819_bases
ATGACGCGCGCGATCAAAGCCGCAAGCGCCGCGACCGAGGCCGGCGCGCTCGGCGCCGCGGGCCGGCGCGCGCCCGTCAT
GCTCGCGCGCGTCGCCGCGCTGGCCGCGCTCGCCGTGATGCTCGCGCGGCCCGGCTGGCTCGAGCCCCTTTTCGCGCCGT
TCGCCGACAACGGCGCGCCCGCGATCTACCGGCGCGCGAGCCTTCTCGATTTGACGCTGTCGCATCTCGCGATCGTCGGC
GCGGCGAGCGCGGCGGGCGCGGTCGTCGCGCTCGCGGCCGGGATTTTCGTCACGCGGCGCGCGGGCGCGGAATTCCTGCC
GGTCGCGCGCAGCGTCGTGCATATCGGGCAGACCTTTCCGCCCGTCGCAGTGCTCGCGCTCGCGGTGCCGGCCGTCGGCT
TCGGCGTGAAGCCCGTGCTGATCGCGCTGATCCTGTACGGGCTGCTGCCGATCTTCGAAAGCACGATCGCGGGGCTGCAG
GACGTGCCCGCCGGCGCCGTCGACGCGGCGCGCGCAATGGGCATGAGCGCGCTGCAGCGGCTCGCGTGGATCGAGCTGCC
GCTCGCGTTTCCGGTGGTCCTGAACGGCATCCGGCTCGCGGTCGTCATCAATCTCGGCACGGCGACGATCGGCTCGACCG
TCGCGGCGAAGGGGCTCGGCGACGTGATCATCGCGGGGCTGCAGACATCGAACACCGCGTTCGTGCTGCAAGGCGGGCTC
GTCGTCGCGCTGCTCGCGGTGCTGATCTACGACGCGCTCGGCGTGATCGGCCGATGGCTCGCGCCGGCGAGCGCGGCGCG
CGAAGAAGGCGGCGCGTAG

Upstream 100 bases:

>100_bases
TGTGGCGCGGCGCGCGCGCGCTGCCCGTATCGAGCGCCGACGGCGCGGCGGCAAGGCGCATCACGCTCGATGCGATCGTC
GCGCAGGCGAAGCGGCCGGC

Downstream 100 bases:

>100_bases
CGCACGAGTACGCGACAGGCGGCCGAATGCGGACGATGGCGGCCGAATGCGCCGGCGCGCGAGCGCGTGCGGCCGCGCGC
CGCCGCCGAGCCCCCGGAAC

Product: amine ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTRAIKAASAATEAGALGAAGRRAPVMLARVAALAALAVMLARPGWLEPLFAPFADNGAPAIYRRASLLDLTLSHLAIVG
AASAAGAVVALAAGIFVTRRAGAEFLPVARSVVHIGQTFPPVAVLALAVPAVGFGVKPVLIALILYGLLPIFESTIAGLQ
DVPAGAVDAARAMGMSALQRLAWIELPLAFPVVLNGIRLAVVINLGTATIGSTVAAKGLGDVIIAGLQTSNTAFVLQGGL
VVALLAVLIYDALGVIGRWLAPASAAREEGGA

Sequences:

>Translated_272_residues
MTRAIKAASAATEAGALGAAGRRAPVMLARVAALAALAVMLARPGWLEPLFAPFADNGAPAIYRRASLLDLTLSHLAIVG
AASAAGAVVALAAGIFVTRRAGAEFLPVARSVVHIGQTFPPVAVLALAVPAVGFGVKPVLIALILYGLLPIFESTIAGLQ
DVPAGAVDAARAMGMSALQRLAWIELPLAFPVVLNGIRLAVVINLGTATIGSTVAAKGLGDVIIAGLQTSNTAFVLQGGL
VVALLAVLIYDALGVIGRWLAPASAAREEGGA
>Mature_271_residues
TRAIKAASAATEAGALGAAGRRAPVMLARVAALAALAVMLARPGWLEPLFAPFADNGAPAIYRRASLLDLTLSHLAIVGA
ASAAGAVVALAAGIFVTRRAGAEFLPVARSVVHIGQTFPPVAVLALAVPAVGFGVKPVLIALILYGLLPIFESTIAGLQD
VPAGAVDAARAMGMSALQRLAWIELPLAFPVVLNGIRLAVVINLGTATIGSTVAAKGLGDVIIAGLQTSNTAFVLQGGLV
VALLAVLIYDALGVIGRWLAPASAAREEGGA

Specific function: May be part of an ABC transporter complex involved in uptake of osmoprotectant molecules. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=206, Percent_Identity=50, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1788451, Length=210, Percent_Identity=36.6666666666667, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789033, Length=171, Percent_Identity=29.8245614035088, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 27283; Mature: 27152

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRAIKAASAATEAGALGAAGRRAPVMLARVAALAALAVMLARPGWLEPLFAPFADNGAP
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCC
AIYRRASLLDLTLSHLAIVGAASAAGAVVALAAGIFVTRRAGAEFLPVARSVVHIGQTFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCH
PVAVLALAVPAVGFGVKPVLIALILYGLLPIFESTIAGLQDVPAGAVDAARAMGMSALQR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LAWIELPLAFPVVLNGIRLAVVINLGTATIGSTVAAKGLGDVIIAGLQTSNTAFVLQGGL
HHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHCCCHHHEECCCCCCEEEEEECCH
VVALLAVLIYDALGVIGRWLAPASAAREEGGA
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCC
>Mature Secondary Structure 
TRAIKAASAATEAGALGAAGRRAPVMLARVAALAALAVMLARPGWLEPLFAPFADNGAP
CCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCC
AIYRRASLLDLTLSHLAIVGAASAAGAVVALAAGIFVTRRAGAEFLPVARSVVHIGQTFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCH
PVAVLALAVPAVGFGVKPVLIALILYGLLPIFESTIAGLQDVPAGAVDAARAMGMSALQR
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LAWIELPLAFPVVLNGIRLAVVINLGTATIGSTVAAKGLGDVIIAGLQTSNTAFVLQGGL
HHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHCCCHHHEECCCCCCEEEEEECCH
VVALLAVLIYDALGVIGRWLAPASAAREEGGA
HHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]