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The map label for this gene is aroC [H]

Identifier: 237811995

GI number: 237811995

Start: 1682069

End: 1683460

Strand: Direct

Name: aroC [H]

Synonym: GBP346_A1735

Alternate gene names: 237811995

Gene position: 1682069-1683460 (Clockwise)

Preceding gene: 237811994

Following gene: 237811996

Centisome position: 41.04

GC content: 71.77

Gene sequence:

>1392_bases
ATGGCGGCGGGCGGCGCGCGCGGACATCGATCGCGCGGCAGCGGGCGGCGCATGACACGGCTCGTGCGCAGGCGAGCCGC
GGCACGCGCCGATCGGCGCGTGCGTCCGCCGTTTCGGGCGGCGCGTGCGAAGCCCGCGCGCGATATCGGCCGCCGCGCCG
CGCGCATGCTCGGCCGCGCACGGTCGCGCGGCGCCGCCCGATCGCGCGCCATATCGCCGCATTGCCCGAAACGGGCTGGC
ATAATGACGGTTTCCCCGACTGACTTTCTTTTGGACGGCCCTATGTCCGGCAACACCCTCGGCACGCTTTTCACTGTCAC
GACCTTCGGCGAATCGCACGGCCCCGCGATCGGCTGCGTGATCGACGGCTGCCCGCCGGGCATGGCGCTCACGGAAGCCG
ACGTCCAGCTCGAGCTCGACCGCCGCAAGCCCGGCACGTCGCGCCACGTCACGCAGCGTCAGGAGCCCGACCAGGTCGAG
ATCCTGTCCGGCGTGTTCGAGGGCGTGACGACCGGCGCGCCGATCGCGCTCCTGATCCGCAACACCGACCAGCGCAGCAA
GGACTACGGCAACATCGCCGAGACGTTCCGGCCGGGCCATGCCGATTACACCTACTGGCAGAAGTACGGCGTGCGCGACT
ATCGCGGCGGCGGCCGCTCGTCCGCGCGGCTGACGGCGCCCGTCGTCGGCGCCGGCGCGATCGCGAAGAAGTGGCTGCGC
GAGCGCTTCGGCGTCGAGGTGCGCGGCTACATGAGCGCGCTCGGCGAAATCGAGATCCCGTTCGTCGACTGGTCGCACGT
GCGCGAGAACCCGTTCTTCGCGCCGAACGCCGACATCGTGCCGCAACTCGAGGGCTACATGGACGCGCTGCGCAAGGACG
GCGATTCGATCGGCGCGCGCATCGATGTCGTCGCGTCGGGCGTGCCGGTCGGCTGGGGCGAGCCGCTGTTCGACCGGCTC
GACGCCGACATCGCGCACGCGATGATGGGGATCAACGCGGTGAAGGGCGTCGAGATCGGCGCGGGCTTCGCGAGCGTCGC
GCAGCGCGGTTCGGTGCACGGCGACGAGCTGACGCCGGACGGCTTCGTCGGCAATCACGCGGGCGGCGTGCTCGGCGGCA
TCTCGACGGGGCAGGACATCACGGTGTCGATCGCGATCAAGCCGACGTCGAGCATTCGCACGCCGCGCCGCTCGATCACG
CGGGCGGGCGAACCCGCCGTCGTCGAGACGTTCGGCCGCCACGACCCGTGCGTCGGGATTCGCGCGACGCCGATCGCCGA
ATCGATGCTCGCGCTCGTGCTGATCGATCACGCGCTGCGGCACCGCGCGCAGTGCGGCGACGTGTCGAGCGCGACGCCGA
GGATCGCCGCGCGCGCGCCGGACGCGCAATGA

Upstream 100 bases:

>100_bases
GCGGCGCGCGCAAGTAGGCGGCGCGGGCAGGCAGGCGGTGCGCGGCGCGGTTCCGCCCAGGTTCGTGCGGCGTGGCGCGC
GCCGGTAGCGGCTTCGTCGG

Downstream 100 bases:

>100_bases
GCGTGATCGGACGGCGAGCCGAGGGCGTCGCGCGCCATTCGCGCCGCCGGCCGGCGCGCGATGCCGGCATCAAAACGGCA
TCAAAACGAAAACGGGCGCC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MAAGGARGHRSRGSGRRMTRLVRRRAAARADRRVRPPFRAARAKPARDIGRRAARMLGRARSRGAARSRAISPHCPKRAG
IMTVSPTDFLLDGPMSGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGMALTEADVQLELDRRKPGTSRHVTQRQEPDQVE
ILSGVFEGVTTGAPIALLIRNTDQRSKDYGNIAETFRPGHADYTYWQKYGVRDYRGGGRSSARLTAPVVGAGAIAKKWLR
ERFGVEVRGYMSALGEIEIPFVDWSHVRENPFFAPNADIVPQLEGYMDALRKDGDSIGARIDVVASGVPVGWGEPLFDRL
DADIAHAMMGINAVKGVEIGAGFASVAQRGSVHGDELTPDGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSIT
RAGEPAVVETFGRHDPCVGIRATPIAESMLALVLIDHALRHRAQCGDVSSATPRIAARAPDAQ

Sequences:

>Translated_463_residues
MAAGGARGHRSRGSGRRMTRLVRRRAAARADRRVRPPFRAARAKPARDIGRRAARMLGRARSRGAARSRAISPHCPKRAG
IMTVSPTDFLLDGPMSGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGMALTEADVQLELDRRKPGTSRHVTQRQEPDQVE
ILSGVFEGVTTGAPIALLIRNTDQRSKDYGNIAETFRPGHADYTYWQKYGVRDYRGGGRSSARLTAPVVGAGAIAKKWLR
ERFGVEVRGYMSALGEIEIPFVDWSHVRENPFFAPNADIVPQLEGYMDALRKDGDSIGARIDVVASGVPVGWGEPLFDRL
DADIAHAMMGINAVKGVEIGAGFASVAQRGSVHGDELTPDGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSIT
RAGEPAVVETFGRHDPCVGIRATPIAESMLALVLIDHALRHRAQCGDVSSATPRIAARAPDAQ
>Mature_462_residues
AAGGARGHRSRGSGRRMTRLVRRRAAARADRRVRPPFRAARAKPARDIGRRAARMLGRARSRGAARSRAISPHCPKRAGI
MTVSPTDFLLDGPMSGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGMALTEADVQLELDRRKPGTSRHVTQRQEPDQVEI
LSGVFEGVTTGAPIALLIRNTDQRSKDYGNIAETFRPGHADYTYWQKYGVRDYRGGGRSSARLTAPVVGAGAIAKKWLRE
RFGVEVRGYMSALGEIEIPFVDWSHVRENPFFAPNADIVPQLEGYMDALRKDGDSIGARIDVVASGVPVGWGEPLFDRLD
ADIAHAMMGINAVKGVEIGAGFASVAQRGSVHGDELTPDGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSITR
AGEPAVVETFGRHDPCVGIRATPIAESMLALVLIDHALRHRAQCGDVSSATPRIAARAPDAQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=360, Percent_Identity=67.2222222222222, Blast_Score=479, Evalue=1e-136,
Organism=Saccharomyces cerevisiae, GI6321290, Length=369, Percent_Identity=42.8184281842818, Blast_Score=290, Evalue=4e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 49524; Mature: 49393

Theoretical pI: Translated: 10.72; Mature: 10.72

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAGGARGHRSRGSGRRMTRLVRRRAAARADRRVRPPFRAARAKPARDIGRRAARMLGRA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHH
RSRGAARSRAISPHCPKRAGIMTVSPTDFLLDGPMSGNTLGTLFTVTTFGESHGPAIGCV
HHCCHHHHCCCCCCCCCCCCEEEECCCCEEEECCCCCCCEEEEEEEEECCCCCCCEEEEE
IDGCPPGMALTEADVQLELDRRKPGTSRHVTQRQEPDQVEILSGVFEGVTTGAPIALLIR
EECCCCCCEEECCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEE
NTDQRSKDYGNIAETFRPGHADYTYWQKYGVRDYRGGGRSSARLTAPVVGAGAIAKKWLR
CCCCCCCHHCCHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHH
ERFGVEVRGYMSALGEIEIPFVDWSHVRENPFFAPNADIVPQLEGYMDALRKDGDSIGAR
HHHCCCHHHHHHHCCCEEEEECCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCE
IDVVASGVPVGWGEPLFDRLDADIAHAMMGINAVKGVEIGAGFASVAQRGSVHGDELTPD
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHCCCCCCCCCCCC
GFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSITRAGEPAVVETFGRHDPCVGI
CCCCCCCCCEEECCCCCCCEEEEEEECCCHHHCCCHHHHHCCCCCHHHHHCCCCCCCCCC
RATPIAESMLALVLIDHALRHRAQCGDVSSATPRIAARAPDAQ
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCC
>Mature Secondary Structure 
AAGGARGHRSRGSGRRMTRLVRRRAAARADRRVRPPFRAARAKPARDIGRRAARMLGRA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHH
RSRGAARSRAISPHCPKRAGIMTVSPTDFLLDGPMSGNTLGTLFTVTTFGESHGPAIGCV
HHCCHHHHCCCCCCCCCCCCEEEECCCCEEEECCCCCCCEEEEEEEEECCCCCCCEEEEE
IDGCPPGMALTEADVQLELDRRKPGTSRHVTQRQEPDQVEILSGVFEGVTTGAPIALLIR
EECCCCCCEEECCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEE
NTDQRSKDYGNIAETFRPGHADYTYWQKYGVRDYRGGGRSSARLTAPVVGAGAIAKKWLR
CCCCCCCHHCCHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHH
ERFGVEVRGYMSALGEIEIPFVDWSHVRENPFFAPNADIVPQLEGYMDALRKDGDSIGAR
HHHCCCHHHHHHHCCCEEEEECCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCE
IDVVASGVPVGWGEPLFDRLDADIAHAMMGINAVKGVEIGAGFASVAQRGSVHGDELTPD
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHCCCCCCCCCCCC
GFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSITRAGEPAVVETFGRHDPCVGI
CCCCCCCCCEEECCCCCCCEEEEEEECCCHHHCCCHHHHHCCCCCHHHHHCCCCCCCCCC
RATPIAESMLALVLIDHALRHRAQCGDVSSATPRIAARAPDAQ
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA