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The map label for this gene is glnS [H]

Identifier: 237811941

GI number: 237811941

Start: 1616896

End: 1618902

Strand: Reverse

Name: glnS [H]

Synonym: GBP346_A1681

Alternate gene names: 237811941

Gene position: 1618902-1616896 (Counterclockwise)

Preceding gene: 237811943

Following gene: 237811938

Centisome position: 39.5

GC content: 64.37

Gene sequence:

>2007_bases
ATGGGTCTTCTTCATCATGATGCAGTCTTCGAGAGCGTTGCCGCGCATGGCACGGCGCGGCGGCATGAAATCCGGGTAAA
GAATCCGGGTGAGCGCATCTTAAAAAAGCGAAATCGGGCCGACAAGGCGATTTACGTCCCGTTACAGCGGCAACACATGC
CGGGCCATCCCCCGAAAAACGCGCCGCGCCGCCCGCCGCAAGGGGCGCCGCTCCTCATGACGGTCGTCCGTCAGGTAGAA
TTGACGTATTCGGGCGGCGCGCCATGCGCCCCCTCCCCTTTTCTTCCCCTGTTCCGCATGAGCACCGAACGCAACGACGC
CACCGCGCCTTCCAATTTCATCCGCAACATCATCGACGACGACAACCGCACGGGCAAATGGAGCGGGCGCGTCGAAACGC
GCTTTCCGCCCGAGCCGAACGGCTATCTGCACATCGGTCATGCGAAGAGCATTTGCCTGAACTTCAGCGTCGCGCGCGAC
TACGGCGGCGTGTGCCATCTGCGCTTCGACGATACGAATCCGGAAAAGGAAAGCGTCGAGTACGTGAACTCGATCGTCGA
CGCGGTGCGCTGGCTCGGCTTCGACTGGCAGAAGGCCGGCGTCGCCCATCAATACTTCGCGAGCGACTACTACGACAAGC
TCTACGAATTCGCCGAGCTGCTGATCCAGCGCGGCTGCGCGTACGTCGACAGCCAAAGCGCCGACGAAATGCGCACGAAC
CGCGGCTCGCTCACCGAGCCGGGCACGCCGTCGCCGTTCCGCGACCGCTCGCCCGACGAAAACCTCGCGCTGTTTCGCCG
GATGAAGGCGGGCGAGTTCGCCGAAGGCGAGCACGTGCTGCGCGCGAAGATCGACATGAGCTCGCCGAACATGAACATGC
GCGACCCGGTGATCTACCGGATCCGCTACGCGCATCACTACCGGACGGGCGACAAGTGGTGCGTGTACCCGATGTACGAC
TACACGCACTGCATCTCGGATGCGCTCGAAGGCATCACGCACTCGCTGTGCACGCTCGAATTCGAGGATCACCGCCCGCT
CTACGACTGGGTGCTCAACCAGCTCGCCGACGCCGGCGTGTTCGCGCGGCCGCTGCCGCAGCAAATCGAATTCTCGCGTC
TGAACCTCACCTATGCGATCACGAGCAAGCGCAAATTGCTGCAGCTCGTGACGGAAGGCCACGTCGACGACTGGGACGAT
CCGCGGATGCCGACGATCGTCGGCGTGCGCCGCCGCGGCTTCACGCCGGAGAGCATCCAGTTGTTCTGCGAGCGGATCGG
CGTGACGAAGGTCGATTCGTGGATCGACATGAGCGTGTTCGAAGGCGCGCTGCGCGACGATCTCGACGACAAGGCGCCGC
GCACGGTCGCCGTGCTCGATCCGCTCAAGCTCGTCATCGACAACTACCCGCAAGGCCAGAGCGAGGAATGCACGGCGCCC
GTGCACCCGCACCACCCGGAGCGCGGCCAGCGCACGTTCCCGATCTCGCGCGAGCTGTGGATCGAGCGCGAGGATTTCAG
CGAGCATCCGCCGAAGGGCTATTTCCGGCTGTTCCCGGGCAACAAGGTGCGGCTGCGCTACGGCTACGTGATCGAATGCA
CGGGCGCGGACAAGGACGAGCACGGCAACGTGACCGCCGTGCACTGCAACTACTATCCGGATAGCAAGTCGGGCACCGAA
GGCGCGAACAACTACAAGGTGAAGGGCAACATCCACTGGGTGAGCGCCGCGCACGCGTGCCCCGCCGAAGTGCGGATCTA
CGATCGCCTGTTCAAGGAACCGCATCCGGACGCGGGCGGGCGCAACTTCCTCGAGGCGCTGAATCCGGATTCGAAGAAGA
TCGTTCAGGCGTACCTCGAGCCGGGCGCGCGCGACGCGCTGCCGGAGGCGCGCTATCAGTTCGAGCGGCACGGCTACTTC
GTCGCCGATCGCGTCGATTCGAAGCCCGGCCAGCCGGTGTTCAACCGGATCGTCGGCCTGCGCGACAGCTGGGGCAAGCC
GGCCTGA

Upstream 100 bases:

>100_bases
CCGCCGCCGCGCCGATGCCGGCGTTGCGTTGCGTGCGGTTCATCGCGCACGCGCCGAGGCTGGCGAGCACGACGGCGATG
ACGGTGGCGCGAACGAGAAA

Downstream 100 bases:

>100_bases
TAACCGCGGCGCGGGACGACCCGCGCGACGCGGCGCCGAAAGGAGAATGCCCGGTGCGAGCCGGGCATTTTCATTTTTCG
TTTTCATGTTCGCTAGACGC

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 668; Mature: 667

Protein sequence:

>668_residues
MGLLHHDAVFESVAAHGTARRHEIRVKNPGERILKKRNRADKAIYVPLQRQHMPGHPPKNAPRRPPQGAPLLMTVVRQVE
LTYSGGAPCAPSPFLPLFRMSTERNDATAPSNFIRNIIDDDNRTGKWSGRVETRFPPEPNGYLHIGHAKSICLNFSVARD
YGGVCHLRFDDTNPEKESVEYVNSIVDAVRWLGFDWQKAGVAHQYFASDYYDKLYEFAELLIQRGCAYVDSQSADEMRTN
RGSLTEPGTPSPFRDRSPDENLALFRRMKAGEFAEGEHVLRAKIDMSSPNMNMRDPVIYRIRYAHHYRTGDKWCVYPMYD
YTHCISDALEGITHSLCTLEFEDHRPLYDWVLNQLADAGVFARPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDDWDD
PRMPTIVGVRRRGFTPESIQLFCERIGVTKVDSWIDMSVFEGALRDDLDDKAPRTVAVLDPLKLVIDNYPQGQSEECTAP
VHPHHPERGQRTFPISRELWIEREDFSEHPPKGYFRLFPGNKVRLRYGYVIECTGADKDEHGNVTAVHCNYYPDSKSGTE
GANNYKVKGNIHWVSAAHACPAEVRIYDRLFKEPHPDAGGRNFLEALNPDSKKIVQAYLEPGARDALPEARYQFERHGYF
VADRVDSKPGQPVFNRIVGLRDSWGKPA

Sequences:

>Translated_668_residues
MGLLHHDAVFESVAAHGTARRHEIRVKNPGERILKKRNRADKAIYVPLQRQHMPGHPPKNAPRRPPQGAPLLMTVVRQVE
LTYSGGAPCAPSPFLPLFRMSTERNDATAPSNFIRNIIDDDNRTGKWSGRVETRFPPEPNGYLHIGHAKSICLNFSVARD
YGGVCHLRFDDTNPEKESVEYVNSIVDAVRWLGFDWQKAGVAHQYFASDYYDKLYEFAELLIQRGCAYVDSQSADEMRTN
RGSLTEPGTPSPFRDRSPDENLALFRRMKAGEFAEGEHVLRAKIDMSSPNMNMRDPVIYRIRYAHHYRTGDKWCVYPMYD
YTHCISDALEGITHSLCTLEFEDHRPLYDWVLNQLADAGVFARPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDDWDD
PRMPTIVGVRRRGFTPESIQLFCERIGVTKVDSWIDMSVFEGALRDDLDDKAPRTVAVLDPLKLVIDNYPQGQSEECTAP
VHPHHPERGQRTFPISRELWIEREDFSEHPPKGYFRLFPGNKVRLRYGYVIECTGADKDEHGNVTAVHCNYYPDSKSGTE
GANNYKVKGNIHWVSAAHACPAEVRIYDRLFKEPHPDAGGRNFLEALNPDSKKIVQAYLEPGARDALPEARYQFERHGYF
VADRVDSKPGQPVFNRIVGLRDSWGKPA
>Mature_667_residues
GLLHHDAVFESVAAHGTARRHEIRVKNPGERILKKRNRADKAIYVPLQRQHMPGHPPKNAPRRPPQGAPLLMTVVRQVEL
TYSGGAPCAPSPFLPLFRMSTERNDATAPSNFIRNIIDDDNRTGKWSGRVETRFPPEPNGYLHIGHAKSICLNFSVARDY
GGVCHLRFDDTNPEKESVEYVNSIVDAVRWLGFDWQKAGVAHQYFASDYYDKLYEFAELLIQRGCAYVDSQSADEMRTNR
GSLTEPGTPSPFRDRSPDENLALFRRMKAGEFAEGEHVLRAKIDMSSPNMNMRDPVIYRIRYAHHYRTGDKWCVYPMYDY
THCISDALEGITHSLCTLEFEDHRPLYDWVLNQLADAGVFARPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDDWDDP
RMPTIVGVRRRGFTPESIQLFCERIGVTKVDSWIDMSVFEGALRDDLDDKAPRTVAVLDPLKLVIDNYPQGQSEECTAPV
HPHHPERGQRTFPISRELWIEREDFSEHPPKGYFRLFPGNKVRLRYGYVIECTGADKDEHGNVTAVHCNYYPDSKSGTEG
ANNYKVKGNIHWVSAAHACPAEVRIYDRLFKEPHPDAGGRNFLEALNPDSKKIVQAYLEPGARDALPEARYQFERHGYFV
ADRVDSKPGQPVFNRIVGLRDSWGKPA

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=545, Percent_Identity=45.6880733944954, Blast_Score=438, Evalue=1e-122,
Organism=Homo sapiens, GI62241042, Length=533, Percent_Identity=34.3339587242026, Blast_Score=259, Evalue=6e-69,
Organism=Escherichia coli, GI1786895, Length=558, Percent_Identity=57.3476702508961, Blast_Score=652, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=99, Percent_Identity=31.3131313131313, Blast_Score=73, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17543332, Length=544, Percent_Identity=43.1985294117647, Blast_Score=404, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17511007, Length=534, Percent_Identity=31.6479400749064, Blast_Score=229, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6324742, Length=578, Percent_Identity=41.6955017301038, Blast_Score=412, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6321192, Length=529, Percent_Identity=32.703213610586, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI17864488, Length=551, Percent_Identity=42.1052631578947, Blast_Score=414, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24649466, Length=425, Percent_Identity=36.7058823529412, Blast_Score=240, Evalue=3e-63,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 76214; Mature: 76082

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLHHDAVFESVAAHGTARRHEIRVKNPGERILKKRNRADKAIYVPLQRQHMPGHPPKN
CCCCHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCC
APRRPPQGAPLLMTVVRQVELTYSGGAPCAPSPFLPLFRMSTERNDATAPSNFIRNIIDD
CCCCCCCCCHHHHHHHHHHEEEECCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHCC
DNRTGKWSGRVETRFPPEPNGYLHIGHAKSICLNFSVARDYGGVCHLRFDDTNPEKESVE
CCCCCCCCCEECCCCCCCCCCEEEECCCCEEEEEEEEECCCCCEEEEEECCCCCCHHHHH
YVNSIVDAVRWLGFDWQKAGVAHQYFASDYYDKLYEFAELLIQRGCAYVDSQSADEMRTN
HHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHC
RGSLTEPGTPSPFRDRSPDENLALFRRMKAGEFAEGEHVLRAKIDMSSPNMNMRDPVIYR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCEEEE
IRYAHHYRTGDKWCVYPMYDYTHCISDALEGITHSLCTLEFEDHRPLYDWVLNQLADAGV
EEEHHEECCCCCEEEEECHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHCCC
FARPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDDWDDPRMPTIVGVRRRGFTPESIQ
CCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCEEEHHHCCCCHHHHH
LFCERIGVTKVDSWIDMSVFEGALRDDLDDKAPRTVAVLDPLKLVIDNYPQGQSEECTAP
HHHHHCCCCHHCHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCCCC
VHPHHPERGQRTFPISRELWIEREDFSEHPPKGYFRLFPGNKVRLRYGYVIECTGADKDE
CCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCCEEEECCCCEEEEEEEEEEEECCCCCCC
HGNVTAVHCNYYPDSKSGTEGANNYKVKGNIHWVSAAHACPAEVRIYDRLFKEPHPDAGG
CCCEEEEEEEECCCCCCCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCC
RNFLEALNPDSKKIVQAYLEPGARDALPEARYQFERHGYFVADRVDSKPGQPVFNRIVGL
HHHHHHCCCCHHHHHHHHHCCCCHHCCCHHHHHHHHCCEEEEECCCCCCCCHHHHHHHCC
RDSWGKPA
CCCCCCCC
>Mature Secondary Structure 
GLLHHDAVFESVAAHGTARRHEIRVKNPGERILKKRNRADKAIYVPLQRQHMPGHPPKN
CCCHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCC
APRRPPQGAPLLMTVVRQVELTYSGGAPCAPSPFLPLFRMSTERNDATAPSNFIRNIIDD
CCCCCCCCCHHHHHHHHHHEEEECCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHCC
DNRTGKWSGRVETRFPPEPNGYLHIGHAKSICLNFSVARDYGGVCHLRFDDTNPEKESVE
CCCCCCCCCEECCCCCCCCCCEEEECCCCEEEEEEEEECCCCCEEEEEECCCCCCHHHHH
YVNSIVDAVRWLGFDWQKAGVAHQYFASDYYDKLYEFAELLIQRGCAYVDSQSADEMRTN
HHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHC
RGSLTEPGTPSPFRDRSPDENLALFRRMKAGEFAEGEHVLRAKIDMSSPNMNMRDPVIYR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCEEEE
IRYAHHYRTGDKWCVYPMYDYTHCISDALEGITHSLCTLEFEDHRPLYDWVLNQLADAGV
EEEHHEECCCCCEEEEECHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHCCC
FARPLPQQIEFSRLNLTYAITSKRKLLQLVTEGHVDDWDDPRMPTIVGVRRRGFTPESIQ
CCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCEEEHHHCCCCHHHHH
LFCERIGVTKVDSWIDMSVFEGALRDDLDDKAPRTVAVLDPLKLVIDNYPQGQSEECTAP
HHHHHCCCCHHCHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHCCCCCCCCCCCCCC
VHPHHPERGQRTFPISRELWIEREDFSEHPPKGYFRLFPGNKVRLRYGYVIECTGADKDE
CCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCCEEEECCCCEEEEEEEEEEEECCCCCCC
HGNVTAVHCNYYPDSKSGTEGANNYKVKGNIHWVSAAHACPAEVRIYDRLFKEPHPDAGG
CCCEEEEEEEECCCCCCCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCC
RNFLEALNPDSKKIVQAYLEPGARDALPEARYQFERHGYFVADRVDSKPGQPVFNRIVGL
HHHHHHCCCCHHHHHHHHHCCCCHHCCCHHHHHHHHCCEEEEECCCCCCCCHHHHHHHCC
RDSWGKPA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA