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The map label for this gene is gluQ [H]

Identifier: 237811492

GI number: 237811492

Start: 1177565

End: 1178458

Strand: Reverse

Name: gluQ [H]

Synonym: GBP346_A1222

Alternate gene names: 237811492

Gene position: 1178458-1177565 (Counterclockwise)

Preceding gene: 237811493

Following gene: 237811491

Centisome position: 28.75

GC content: 74.16

Gene sequence:

>894_bases
ATGACACGCTATCGCGGGCGCTTCGCGCCGTCGCCCACCGGCCCCCTGCACTTCGGCTCGCTCGTCGGCGCGCTCGCGAG
CTGGCTCGACGCGCGCGCGTGGGGCGGCGCGTGGCTCGTGCGAATCGAGGATATCGACGGCCCGCGCACGGTGCCCGGCG
CGGCCGAAGACATGCTCGCGACGCTGCGCGGCTTCGGCTTCATCGCCGACGAGCCGCCCGTCTGGCAAAGCGCGCGCGTC
GCGCACTACGAAGCGGCGCTCGCGCGGCTCACCGCCGCGGGGCTCGTCTATCCGTGCGGCTGCTCGCGCAAGGAGATCGC
CGATTCGCTGCGCGCCGCGCACGAGCGGCACACGACGCTCGCGTATCCCGGCACGTGCCGCACGGGCCTGCACGGCAAGC
CCGCGCGCGCATGGCGCTTGCGCGTGCCGGACGGCGCCGCGGCCGTCGTCGCGTTCGACGACCGCTGGCAGCGCGCGCAA
ACGCAGAATCTCGCGACCGAAGTCGGCGATTTCGTGCTGAAGCGCGCGGACGGACAATGGGCGTATCAACTCGCCGTCGT
CGTCGACGACGGCGATGCGAACATCACGCACGTCGTGCGCGGCGCCGATCTGCTCGACTCGACCGCTCGCCAGATCTACC
TGCAGCGCTGCCTCGGGCTGCCGACGCCGCGCTATCTGCACGTGCCTGTCGTCCTCGACGCGAACGGCGAGAAGCTCAGC
AAGCAAACGGGCGCGGCGGCGCTCGATCCCGCCGCGCCGCTGCCGGCGCTCGCCGCCGCCGCGCGGCACCTGGGGCTCGC
GCTCGACGGCGCGGCGTGCGCGTCGCTCGACGCGTTCCAGGCGGCCGCGATCGCCGCGTGGGACACGCGCTTCGGGCCGA
ACGCGCGCGGCTGA

Upstream 100 bases:

>100_bases
TCCGGCACGCCGGGCCGGCGCGCGGAGCCGGGCGCCGAACCGGCGCGCGCCGTGTGAGCCCGCGCCGCCCATTGCTCCGC
GTCGCCGCGCGCCGCATCGA

Downstream 100 bases:

>100_bases
AGACACCAGCCGGATGATGCGGCATGGTCGCTTCGACCGGCGTTGCGACCGTCGCGCCGCTACGCCGGCGCACCGTCGGC
GATCGCCGAGCCGGCGATTC

Product: glutamyl-Q tRNA(Asp) synthetase

Products: NA

Alternate protein names: Glu-Q-RSs [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTRYRGRFAPSPTGPLHFGSLVGALASWLDARAWGGAWLVRIEDIDGPRTVPGAAEDMLATLRGFGFIADEPPVWQSARV
AHYEAALARLTAAGLVYPCGCSRKEIADSLRAAHERHTTLAYPGTCRTGLHGKPARAWRLRVPDGAAAVVAFDDRWQRAQ
TQNLATEVGDFVLKRADGQWAYQLAVVVDDGDANITHVVRGADLLDSTARQIYLQRCLGLPTPRYLHVPVVLDANGEKLS
KQTGAAALDPAAPLPALAAAARHLGLALDGAACASLDAFQAAAIAAWDTRFGPNARG

Sequences:

>Translated_297_residues
MTRYRGRFAPSPTGPLHFGSLVGALASWLDARAWGGAWLVRIEDIDGPRTVPGAAEDMLATLRGFGFIADEPPVWQSARV
AHYEAALARLTAAGLVYPCGCSRKEIADSLRAAHERHTTLAYPGTCRTGLHGKPARAWRLRVPDGAAAVVAFDDRWQRAQ
TQNLATEVGDFVLKRADGQWAYQLAVVVDDGDANITHVVRGADLLDSTARQIYLQRCLGLPTPRYLHVPVVLDANGEKLS
KQTGAAALDPAAPLPALAAAARHLGLALDGAACASLDAFQAAAIAAWDTRFGPNARG
>Mature_296_residues
TRYRGRFAPSPTGPLHFGSLVGALASWLDARAWGGAWLVRIEDIDGPRTVPGAAEDMLATLRGFGFIADEPPVWQSARVA
HYEAALARLTAAGLVYPCGCSRKEIADSLRAAHERHTTLAYPGTCRTGLHGKPARAWRLRVPDGAAAVVAFDDRWQRAQT
QNLATEVGDFVLKRADGQWAYQLAVVVDDGDANITHVVRGADLLDSTARQIYLQRCLGLPTPRYLHVPVVLDANGEKLSK
QTGAAALDPAAPLPALAAAARHLGLALDGAACASLDAFQAAAIAAWDTRFGPNARG

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI134288884, Length=264, Percent_Identity=37.1212121212121, Blast_Score=150, Evalue=1e-36,
Organism=Escherichia coli, GI226510925, Length=264, Percent_Identity=45.8333333333333, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1788743, Length=247, Percent_Identity=35.6275303643725, Blast_Score=158, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI71993394, Length=290, Percent_Identity=31.0344827586207, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324540, Length=259, Percent_Identity=33.2046332046332, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24665321, Length=260, Percent_Identity=34.6153846153846, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c [H]

EC number: NA

Molecular weight: Translated: 31630; Mature: 31499

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRYRGRFAPSPTGPLHFGSLVGALASWLDARAWGGAWLVRIEDIDGPRTVPGAAEDMLA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHH
TLRGFGFIADEPPVWQSARVAHYEAALARLTAAGLVYPCGCSRKEIADSLRAAHERHTTL
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHHCCEE
AYPGTCRTGLHGKPARAWRLRVPDGAAAVVAFDDRWQRAQTQNLATEVGDFVLKRADGQW
ECCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCE
AYQLAVVVDDGDANITHVVRGADLLDSTARQIYLQRCLGLPTPRYLHVPVVLDANGEKLS
EEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHH
KQTGAAALDPAAPLPALAAAARHLGLALDGAACASLDAFQAAAIAAWDTRFGPNARG
HHCCCCCCCCCCCHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHEECCCCCCCCCCC
>Mature Secondary Structure 
TRYRGRFAPSPTGPLHFGSLVGALASWLDARAWGGAWLVRIEDIDGPRTVPGAAEDMLA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHH
TLRGFGFIADEPPVWQSARVAHYEAALARLTAAGLVYPCGCSRKEIADSLRAAHERHTTL
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHHCCEE
AYPGTCRTGLHGKPARAWRLRVPDGAAAVVAFDDRWQRAQTQNLATEVGDFVLKRADGQW
ECCCCCCCCCCCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCE
AYQLAVVVDDGDANITHVVRGADLLDSTARQIYLQRCLGLPTPRYLHVPVVLDANGEKLS
EEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHH
KQTGAAALDPAAPLPALAAAARHLGLALDGAACASLDAFQAAAIAAWDTRFGPNARG
HHCCCCCCCCCCCHHHHHHHHHHHCEEECCHHHHHHHHHHHHHHEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA