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The map label for this gene is sucC

Identifier: 23502776

GI number: 23502776

Start: 1859183

End: 1860379

Strand: Reverse

Name: sucC

Synonym: BR1926

Alternate gene names: 23502776

Gene position: 1860379-1859183 (Counterclockwise)

Preceding gene: 23502777

Following gene: 23502775

Centisome position: 88.26

GC content: 57.64

Gene sequence:

>1197_bases
ATGAATATTCACGAATACCAGGCCAAGCGCCTGCTTCACACCTACGGCGCGCCGATCGCCAATGGTGTGGCTGTCTATTC
CGTCGAACAGGCGGAAGAATGGGCAAAGACGCTTCCCGGACCGCTTTATGTCGTCAAGAGCCAGATCCATGCTGGCGGAC
GCGGCAAGGGCAAGTTCAAGGAACTGCCTGCCGATGCAAAGGGCGGCGTGCGCCTCGCCAAGTCTGTCGAGGAAGTGGTT
GCCAATGCGAAGGAAATGCTGGGCAACACGCTCGTCACCAAGCAGACCGGCGAAGCCGGCAAGCAGGTCAACCGTCTCTA
CATTGAAGATGGCGCCGATATCGAGCGTGAGCTTTATCTCTCCATCCTGATCGACCGCAGCGTTGGCCGTCCGGCCTTTG
TCGTTTCGACCGAAGGCGGCATGGATATTGAAGCCGTTGCCGAAGAAACCCCTGAAAAGATCGTCACCGTCGCCATCGAC
CCGGCCAAGGGCGTGACCGACGAAGATGCCAACAAGCTTGCCGATGCGCTGAAGCTTGAAGGTGGAGCCCGCGAGGACGG
CCTGAAGCTGTTCCCGATCCTTTACAAGGCTTTCACCGAGAAGGACATGAGCCTCCTCGAAATCAATCCGCTGATCGTCA
TGACGAACGGTCGCGTGCGCGTTCTCGATGCCAAGGTTTCGTTCGACAACAACGCCCTGTTCCGTCACCCGGACATTGTT
GAACTGCGCGACCTGACGGAAGAAGATCCGAAGGAAATCGAAGCCTCCAAATATGACCTGGCCTATGTCGCCCTCGATGG
CAATATCGGCTGCATGGTCAATGGCGCCGGCCTTGCCATGGCGACGATGGACATCATCAAGCTCTATGGCGCAGAACCTG
CCAACTTCCTCGATGTTGGCGGCGGCGCTTCCAAGGAGAAGGTGACGGCTGCGTTCAAGATCATCACCGCCGATCCGGCT
GTCGAAGGCATTCTGGTCAACATTTTCGGCGGCATCATGAAGTGCGATGTCATTGCCGAAGGCGTGATCGCCGCGGTCAA
GGAAGTCGGCCTCAAGGTTCCGCTGGTTGTCCGTCTCGAAGGCACCAATGTCGAGCTTGGCAAGAAGATCATCAACGAGA
GCGGCCTGAACGTCATTTCGGCCGACGATCTCGACGATGCGGCGCAGAAGATCGTCGCTGCAGTGAAGGGGAATTAA

Upstream 100 bases:

>100_bases
GACAAGGCCGGAATTCTGCTTGAGTGCGATTCCGGCCTTTTCCGGCTGTCAATCCGTACTGGCTCGTTGAACGGGCCGGG
AATTTGCAGAGGACAACCAG

Downstream 100 bases:

>100_bases
GGCATGTCCATTCTCGTCAACAAGGACACCAAGGTTCTCGTGCAGGGCCTGACCGGCAAGACCGGCACTTTCCACACCGA
ACAGGCGCTTGCCTATTACG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNIHEYQAKRLLHTYGAPIANGVAVYSVEQAEEWAKTLPGPLYVVKSQIHAGGRGKGKFKELPADAKGGVRLAKSVEEVV
ANAKEMLGNTLVTKQTGEAGKQVNRLYIEDGADIERELYLSILIDRSVGRPAFVVSTEGGMDIEAVAEETPEKIVTVAID
PAKGVTDEDANKLADALKLEGGAREDGLKLFPILYKAFTEKDMSLLEINPLIVMTNGRVRVLDAKVSFDNNALFRHPDIV
ELRDLTEEDPKEIEASKYDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPA
VEGILVNIFGGIMKCDVIAEGVIAAVKEVGLKVPLVVRLEGTNVELGKKIINESGLNVISADDLDDAAQKIVAAVKGN

Sequences:

>Translated_398_residues
MNIHEYQAKRLLHTYGAPIANGVAVYSVEQAEEWAKTLPGPLYVVKSQIHAGGRGKGKFKELPADAKGGVRLAKSVEEVV
ANAKEMLGNTLVTKQTGEAGKQVNRLYIEDGADIERELYLSILIDRSVGRPAFVVSTEGGMDIEAVAEETPEKIVTVAID
PAKGVTDEDANKLADALKLEGGAREDGLKLFPILYKAFTEKDMSLLEINPLIVMTNGRVRVLDAKVSFDNNALFRHPDIV
ELRDLTEEDPKEIEASKYDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPA
VEGILVNIFGGIMKCDVIAEGVIAAVKEVGLKVPLVVRLEGTNVELGKKIINESGLNVISADDLDDAAQKIVAAVKGN
>Mature_398_residues
MNIHEYQAKRLLHTYGAPIANGVAVYSVEQAEEWAKTLPGPLYVVKSQIHAGGRGKGKFKELPADAKGGVRLAKSVEEVV
ANAKEMLGNTLVTKQTGEAGKQVNRLYIEDGADIERELYLSILIDRSVGRPAFVVSTEGGMDIEAVAEETPEKIVTVAID
PAKGVTDEDANKLADALKLEGGAREDGLKLFPILYKAFTEKDMSLLEINPLIVMTNGRVRVLDAKVSFDNNALFRHPDIV
ELRDLTEEDPKEIEASKYDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPA
VEGILVNIFGGIMKCDVIAEGVIAAVKEVGLKVPLVVRLEGTNVELGKKIINESGLNVISADDLDDAAQKIVAAVKGN

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=45.6632653061224, Blast_Score=348, Evalue=4e-96,
Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=48.1865284974093, Blast_Score=344, Evalue=1e-94,
Organism=Homo sapiens, GI294862256, Length=365, Percent_Identity=47.6712328767123, Blast_Score=321, Evalue=8e-88,
Organism=Escherichia coli, GI1786948, Length=397, Percent_Identity=53.6523929471033, Blast_Score=397, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17539378, Length=395, Percent_Identity=46.3291139240506, Blast_Score=359, Evalue=1e-99,
Organism=Caenorhabditis elegans, GI17567829, Length=391, Percent_Identity=45.5242966751918, Blast_Score=331, Evalue=5e-91,
Organism=Saccharomyces cerevisiae, GI6321683, Length=395, Percent_Identity=46.3291139240506, Blast_Score=355, Evalue=7e-99,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=50.8816120906801, Blast_Score=374, Evalue=1e-104,
Organism=Drosophila melanogaster, GI161078106, Length=388, Percent_Identity=47.4226804123711, Blast_Score=348, Evalue=4e-96,
Organism=Drosophila melanogaster, GI24645208, Length=388, Percent_Identity=47.4226804123711, Blast_Score=348, Evalue=4e-96,
Organism=Drosophila melanogaster, GI281361397, Length=389, Percent_Identity=47.5578406169666, Blast_Score=348, Evalue=5e-96,
Organism=Drosophila melanogaster, GI281361395, Length=389, Percent_Identity=47.5578406169666, Blast_Score=348, Evalue=5e-96,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_BRUA1 (B2S880)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935763.1
- ProteinModelPortal:   B2S880
- SMR:   B2S880
- GeneID:   6326907
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I18070
- HOGENOM:   HBG315432
- OMA:   NPLIVMK
- ProtClustDB:   PRK00696
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 42527; Mature: 42527

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQAKRLLHTYGAPIANGVAVYSVEQAEEWAKTLPGPLYVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCHHCCEEEEEHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCCHH
ELPADAKGGVRLAKSVEEVVANAKEMLGNTLVTKQTGEAGKQVNRLYIEDGADIERELYL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHEEEEEEECCCCCCHHEEE
SILIDRSVGRPAFVVSTEGGMDIEAVAEETPEKIVTVAIDPAKGVTDEDANKLADALKLE
EEEEECCCCCCEEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCC
GGAREDGLKLFPILYKAFTEKDMSLLEINPLIVMTNGRVRVLDAKVSFDNNALFRHPDIV
CCCCCCCCCHHHHHHHHHHHCCCEEEEECCEEEEECCEEEEEEEEEECCCCEEECCCCCH
ELRDLTEEDPKEIEASKYDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVG
HHHHCCCCCHHHHCCCCEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGASKEKVTAAFKIITADPAVEGILVNIFGGIMKCDVIAEGVIAAVKEVGLKVPLVVRLE
CCCCCHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GTNVELGKKIINESGLNVISADDLDDAAQKIVAAVKGN
CCCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIHEYQAKRLLHTYGAPIANGVAVYSVEQAEEWAKTLPGPLYVVKSQIHAGGRGKGKFK
CCCHHHHHHHHHHHHCCCHHCCEEEEEHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCCHH
ELPADAKGGVRLAKSVEEVVANAKEMLGNTLVTKQTGEAGKQVNRLYIEDGADIERELYL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHEEEEEEECCCCCCHHEEE
SILIDRSVGRPAFVVSTEGGMDIEAVAEETPEKIVTVAIDPAKGVTDEDANKLADALKLE
EEEEECCCCCCEEEEECCCCCCHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHCC
GGAREDGLKLFPILYKAFTEKDMSLLEINPLIVMTNGRVRVLDAKVSFDNNALFRHPDIV
CCCCCCCCCHHHHHHHHHHHCCCEEEEECCEEEEECCEEEEEEEEEECCCCEEECCCCCH
ELRDLTEEDPKEIEASKYDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVG
HHHHCCCCCHHHHCCCCEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCCCCCEEECC
GGASKEKVTAAFKIITADPAVEGILVNIFGGIMKCDVIAEGVIAAVKEVGLKVPLVVRLE
CCCCCHHEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
GTNVELGKKIINESGLNVISADDLDDAAQKIVAAVKGN
CCCHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA