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The map label for this gene is grxC [H]

Identifier: 23502729

GI number: 23502729

Start: 1813266

End: 1813532

Strand: Reverse

Name: grxC [H]

Synonym: BR1876

Alternate gene names: 23502729

Gene position: 1813532-1813266 (Counterclockwise)

Preceding gene: 23502731

Following gene: 23502728

Centisome position: 86.04

GC content: 56.55

Gene sequence:

>267_bases
ATGGTTGACGTCATCATCTATACCCGCCCCGGCTGCCCCTATTGCGCACGGGCAAAGGCGCTTCTGGCCCGAAAGGGTGC
CGAGTTCAATGAAATCGATGCCTCGGCAACGCCGGAATTGCGCGCTGAAATGCAAGAGCGCTCCGGGCGCAATACCTTCC
CGCAGATTTTTATCGGCTCGGTTCATGTCGGCGGCTGCGACGATCTTTATGCACTGGAAGACGAGGGCAAGCTCGATAGC
CTGCTGAAAACCGGCAAACTTATTTAG

Upstream 100 bases:

>100_bases
GCGTGTTGCCTGATTGAAGCAAGCATAATCAAACCAATGTGCGGGGTCTTCCAGATAAAGGTTTTGCCGCTTATATAATG
GGCAAAGAATGGAGTTTCTC

Downstream 100 bases:

>100_bases
AGGTCAAATCATGAGCACCTTTCGCGCTGCCGCAATCCAGATGCGTTCGGGCATTGATGTCGTCCGCAATGTGGAGGCTC
TCGAAAAACTGGTCGCAGAT

Product: glutaredoxin 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 88; Mature: 88

Protein sequence:

>88_residues
MVDVIIYTRPGCPYCARAKALLARKGAEFNEIDASATPELRAEMQERSGRNTFPQIFIGSVHVGGCDDLYALEDEGKLDS
LLKTGKLI

Sequences:

>Translated_88_residues
MVDVIIYTRPGCPYCARAKALLARKGAEFNEIDASATPELRAEMQERSGRNTFPQIFIGSVHVGGCDDLYALEDEGKLDS
LLKTGKLI
>Mature_88_residues
MVDVIIYTRPGCPYCARAKALLARKGAEFNEIDASATPELRAEMQERSGRNTFPQIFIGSVHVGGCDDLYALEDEGKLDS
LLKTGKLI

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI169646776, Length=86, Percent_Identity=38.3720930232558, Blast_Score=65, Evalue=1e-11,
Organism=Homo sapiens, GI4504025, Length=86, Percent_Identity=38.3720930232558, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=57.8313253012048, Blast_Score=100, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9646; Mature: 9646

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDVIIYTRPGCPYCARAKALLARKGAEFNEIDASATPELRAEMQERSGRNTFPQIFIGS
CEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEE
VHVGGCDDLYALEDEGKLDSLLKTGKLI
EEECCCCCEEEECCCCCHHHHHHCCCCC
>Mature Secondary Structure
MVDVIIYTRPGCPYCARAKALLARKGAEFNEIDASATPELRAEMQERSGRNTFPQIFIGS
CEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEE
VHVGGCDDLYALEDEGKLDSLLKTGKLI
EEECCCCCEEEECCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]