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The map label for this gene is yisS [H]

Identifier: 23502465

GI number: 23502465

Start: 1546618

End: 1547574

Strand: Reverse

Name: yisS [H]

Synonym: BR1602

Alternate gene names: 23502465

Gene position: 1547574-1546618 (Counterclockwise)

Preceding gene: 23502466

Following gene: 23502464

Centisome position: 73.42

GC content: 56.53

Gene sequence:

>957_bases
ATGGCACCTCGTATTGCGGTTTTGGGTTGCGGCTATTGGGGCGGCAATCACATTCGTACCCTGAAGAGTCTCGGCGCCCT
TCAGGCAGTTTCAGACTCCAACGCGGAAAAAGCGGAACGATTCGCTTCCGAATTCAACGTTCCCAGCATTCCAGTCGAGG
AACTCTTCATCCATCCGGATATTGATGGCATCGTGCTGGCGCTGCCGCCGCAGCTTCATGCGCAATATGCCATGGAAGCG
GTGAAGAACGGCAAGGATGTTCTGGTTGAAAAGCCGATTGCGCTCGATATTCCCGTAGCGCTTGCCGAAGTTGAGGCCGC
GCGCGAAAATGGCCGCGTGTTCATGGTCGGCCATGTGCTCCGCTTCCATCCGGCTTTTGAAAAGCTTCTCGACATGGTGC
AAAGCGGCGAACTTGGCGATATCCGCTATGTGCATTCGCACCGCGTCGGGCTTGGCAAGTTTCATACCGAATTCGATGCG
CTATGGGATCTCGCGCCGCACGATCTTTCGATGATCCTTGCCATCACCGGCGAGGAGCCGAACGTGGTGCGCGGCGAAGG
CGTTGCTATTCTCGATCATCTGAACGATTTCGCGCATCTTCACATGGAATTTCCGAGCGGAATTCGCGGCCATCTTTTTG
CTTCGCGTCTGAACGCTTATCGCGAACGTCGCCTCAGTGTCACCGGCACCAAGGGCATGGCTGTTTTCGACGATGGCGAA
GCCTGGGAGCGGAAGCTTGCCCTTTACAGGCATGAGGTCTGGCGGGAAAACGACCGCTGGGCTTTCAAGTCCGCTGATCC
GGTCTATATACAAACCGAAGAAGGTATGCCGCTGACGCGCGAATTGCAGCATTTCATGCATTGCATCGAAACGCGTGAAA
CGCCGCGAACCGACGGCAAGGAAGCGATCAGTGTCCTGCGCATTCTCACCGAAGGCACGGTGCGGCATCCGGCCTGA

Upstream 100 bases:

>100_bases
TGCGGAACGAGACCCTGTCAAGCGTTCTTCGCATAGGTTTCATCTTGTTTTCTATCATTTGCACCGATATGGAACTTGGC
ATCAGCAAAGGCTAAGTTTC

Downstream 100 bases:

>100_bases
AGCAGCAGTGCGCAAGCAGCGTAAAATTGTGTAAAGCGGTGTTACAGCACTCGCAAAACTTTGAACGCTCCGGCCATGGC
AGGGCGGGGCGCAAGCGAAT

Product: Gfo/Idh/MocA family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MAPRIAVLGCGYWGGNHIRTLKSLGALQAVSDSNAEKAERFASEFNVPSIPVEELFIHPDIDGIVLALPPQLHAQYAMEA
VKNGKDVLVEKPIALDIPVALAEVEAARENGRVFMVGHVLRFHPAFEKLLDMVQSGELGDIRYVHSHRVGLGKFHTEFDA
LWDLAPHDLSMILAITGEEPNVVRGEGVAILDHLNDFAHLHMEFPSGIRGHLFASRLNAYRERRLSVTGTKGMAVFDDGE
AWERKLALYRHEVWRENDRWAFKSADPVYIQTEEGMPLTRELQHFMHCIETRETPRTDGKEAISVLRILTEGTVRHPA

Sequences:

>Translated_318_residues
MAPRIAVLGCGYWGGNHIRTLKSLGALQAVSDSNAEKAERFASEFNVPSIPVEELFIHPDIDGIVLALPPQLHAQYAMEA
VKNGKDVLVEKPIALDIPVALAEVEAARENGRVFMVGHVLRFHPAFEKLLDMVQSGELGDIRYVHSHRVGLGKFHTEFDA
LWDLAPHDLSMILAITGEEPNVVRGEGVAILDHLNDFAHLHMEFPSGIRGHLFASRLNAYRERRLSVTGTKGMAVFDDGE
AWERKLALYRHEVWRENDRWAFKSADPVYIQTEEGMPLTRELQHFMHCIETRETPRTDGKEAISVLRILTEGTVRHPA
>Mature_317_residues
APRIAVLGCGYWGGNHIRTLKSLGALQAVSDSNAEKAERFASEFNVPSIPVEELFIHPDIDGIVLALPPQLHAQYAMEAV
KNGKDVLVEKPIALDIPVALAEVEAARENGRVFMVGHVLRFHPAFEKLLDMVQSGELGDIRYVHSHRVGLGKFHTEFDAL
WDLAPHDLSMILAITGEEPNVVRGEGVAILDHLNDFAHLHMEFPSGIRGHLFASRLNAYRERRLSVTGTKGMAVFDDGEA
WERKLALYRHEVWRENDRWAFKSADPVYIQTEEGMPLTRELQHFMHCIETRETPRTDGKEAISVLRILTEGTVRHPA

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=251, Percent_Identity=25.8964143426295, Blast_Score=81, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24581117, Length=226, Percent_Identity=25.6637168141593, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35701; Mature: 35570

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPRIAVLGCGYWGGNHIRTLKSLGALQAVSDSNAEKAERFASEFNVPSIPVEELFIHPD
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHEEECCC
IDGIVLALPPQLHAQYAMEAVKNGKDVLVEKPIALDIPVALAEVEAARENGRVFMVGHVL
CCEEEEECCHHHHHHHHHHHHHCCCEEEEECCCEEECCHHHHHHHHHHHCCCEEEEEHHH
RFHPAFEKLLDMVQSGELGDIRYVHSHRVGLGKFHTEFDALWDLAPHDLSMILAITGEEP
HHCHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCC
NVVRGEGVAILDHLNDFAHLHMEFPSGIRGHLFASRLNAYRERRLSVTGTKGMAVFDDGE
CEECCCCEEEEHHHCCHHEEEEECCCCCHHHHHHHHHHHHHHHCEEEECCCCEEEEECCH
AWERKLALYRHEVWRENDRWAFKSADPVYIQTEEGMPLTRELQHFMHCIETRETPRTDGK
HHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHH
EAISVLRILTEGTVRHPA
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
APRIAVLGCGYWGGNHIRTLKSLGALQAVSDSNAEKAERFASEFNVPSIPVEELFIHPD
CCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHEEECCC
IDGIVLALPPQLHAQYAMEAVKNGKDVLVEKPIALDIPVALAEVEAARENGRVFMVGHVL
CCEEEEECCHHHHHHHHHHHHHCCCEEEEECCCEEECCHHHHHHHHHHHCCCEEEEEHHH
RFHPAFEKLLDMVQSGELGDIRYVHSHRVGLGKFHTEFDALWDLAPHDLSMILAITGEEP
HHCHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCC
NVVRGEGVAILDHLNDFAHLHMEFPSGIRGHLFASRLNAYRERRLSVTGTKGMAVFDDGE
CEECCCCEEEEHHHCCHHEEEEECCCCCHHHHHHHHHHHHHHHCEEEECCCCEEEEECCH
AWERKLALYRHEVWRENDRWAFKSADPVYIQTEEGMPLTRELQHFMHCIETRETPRTDGK
HHHHHHHHHHHHHHCCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHH
EAISVLRILTEGTVRHPA
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377; 8407808 [H]