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The map label for this gene is ctrA

Identifier: 23502462

GI number: 23502462

Start: 1543629

End: 1544327

Strand: Reverse

Name: ctrA

Synonym: BR1599

Alternate gene names: 23502462

Gene position: 1544327-1543629 (Counterclockwise)

Preceding gene: 23502464

Following gene: 23502460

Centisome position: 73.27

GC content: 54.94

Gene sequence:

>699_bases
ATGCGCGTCCTTTTGATTGAAGACGACAGTGCTATCGCACAGAGCATTGAGTTGATGCTCAAGTCCGAGAGTTTTAATGT
CTATACGACCGATCTGGGCGAAGAAGGCATCGATCTCGGCAAGCTTTACGACTACGACATCATTCTGCTGGATCTCAATC
TGCCGGATATGTCTGGTTATGAAGTTCTTCGCACCTTGCGTCTGTCCAAGGTGAAGACGCCGATCCTTATCCTTTCCGGC
ATGGCCGGCATCGAGGACAAGGTTCGCGGTCTTGGCTTTGGCGCCGACGATTATATGACCAAGCCGTTCCATAAGGACGA
GCTGATTGCCCGTATCCATGCGATCGTCCGCCGCTCCAAGGGGCATGCCCAGTCGGTCATCACGACGGGCGACCTGGTGG
TCAATCTGGATGCCAAGACGGTGGAAGTCGCAGGCCAGCGCGTTCATCTGACCGGCAAGGAATACCAGATGCTTGAGCTG
CTTTCGCTGCGCAAGGGCACGACGCTCACCAAGGAAATGTTCCTGAACCATCTTTATGGTGGCATGGATGAGCCGGAATT
GAAGATCATCGACGTCTTCATCTGCAAGCTGCGCAAGAAGCTCGACGCCGTTTCCGGCAATCAGAGCTATATCGAAACCG
TCTGGGGGCGTGGTTATGTGCTGCGCGAGCCGGATGCCGAGATGCGCGAAAGCGCCTGA

Upstream 100 bases:

>100_bases
TATTTTGTTAACCATTTGCTGGCACCTTCATACAAAGGCAACGATAGTTCCGTGTGCTGCCGTGAGGGACATCTGGTCGG
CTGCGGAAAGGGGATAAAAG

Downstream 100 bases:

>100_bases
TTCGGGCTGCATGGTCTGAATTGTAAAAAGCTCCGCTTCGGCGGAGCTTTTGCTTTTCAATCACCTGTCTGATGGTCAAA
AAAAGCGCCGGGTGGACCGG

Product: cell cycle transcriptional regulator CtrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MRVLLIEDDSAIAQSIELMLKSESFNVYTTDLGEEGIDLGKLYDYDIILLDLNLPDMSGYEVLRTLRLSKVKTPILILSG
MAGIEDKVRGLGFGADDYMTKPFHKDELIARIHAIVRRSKGHAQSVITTGDLVVNLDAKTVEVAGQRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLDAVSGNQSYIETVWGRGYVLREPDAEMRESA

Sequences:

>Translated_232_residues
MRVLLIEDDSAIAQSIELMLKSESFNVYTTDLGEEGIDLGKLYDYDIILLDLNLPDMSGYEVLRTLRLSKVKTPILILSG
MAGIEDKVRGLGFGADDYMTKPFHKDELIARIHAIVRRSKGHAQSVITTGDLVVNLDAKTVEVAGQRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLDAVSGNQSYIETVWGRGYVLREPDAEMRESA
>Mature_232_residues
MRVLLIEDDSAIAQSIELMLKSESFNVYTTDLGEEGIDLGKLYDYDIILLDLNLPDMSGYEVLRTLRLSKVKTPILILSG
MAGIEDKVRGLGFGADDYMTKPFHKDELIARIHAIVRRSKGHAQSVITTGDLVVNLDAKTVEVAGQRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLDAVSGNQSYIETVWGRGYVLREPDAEMRESA

Specific function: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=35.2678571428571, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=34.6491228070175, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=34.9775784753363, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=33.9366515837104, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=33.1818181818182, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=31.5315315315315, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=31.2217194570136, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=29.5154185022026, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=32.0175438596491, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=30.7692307692308, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=30.5936073059361, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=29.9559471365639, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=25.1101321585903, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=28.0373831775701, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790437, Length=160, Percent_Identity=25, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=25.531914893617, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTRA_BRUA1 (B2S753)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935474.1
- ProteinModelPortal:   B2S753
- SMR:   B2S753
- GeneID:   6327454
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I15100
- HOGENOM:   HBG753323
- OMA:   ISVNLDA
- ProtClustDB:   CLSK863578
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00448
- SMART:   SM00862

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C; SSF52172 CheY_like

EC number: NA

Molecular weight: Translated: 26067; Mature: 26067

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLIEDDSAIAQSIELMLKSESFNVYTTDLGEEGIDLGKLYDYDIILLDLNLPDMSGY
CEEEEEECCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECEEEEEEEECCCCCCHH
EVLRTLRLSKVKTPILILSGMAGIEDKVRGLGFGADDYMTKPFHKDELIARIHAIVRRSK
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHCCC
GHAQSVITTGDLVVNLDAKTVEVAGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CCHHHEEEECCEEEEECCCEEEECCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLDAVSGNQSYIETVWGRGYVLREPDAEMRESA
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCCHHHHCCC
>Mature Secondary Structure
MRVLLIEDDSAIAQSIELMLKSESFNVYTTDLGEEGIDLGKLYDYDIILLDLNLPDMSGY
CEEEEEECCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECEEEEEEEECCCCCCHH
EVLRTLRLSKVKTPILILSGMAGIEDKVRGLGFGADDYMTKPFHKDELIARIHAIVRRSK
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHCCC
GHAQSVITTGDLVVNLDAKTVEVAGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CCHHHEEEECCEEEEECCCEEEECCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLDAVSGNQSYIETVWGRGYVLREPDAEMRESA
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA