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The map label for this gene is trxB [H]

Identifier: 23502368

GI number: 23502368

Start: 1454371

End: 1455345

Strand: Reverse

Name: trxB [H]

Synonym: BR1499

Alternate gene names: 23502368

Gene position: 1455345-1454371 (Counterclockwise)

Preceding gene: 23502372

Following gene: 23502367

Centisome position: 69.05

GC content: 59.79

Gene sequence:

>975_bases
ATGACACAGCGTCACGCGCCAGTTATTGTTATCGGCTCAGGTCCTGCTGGTTATACGGCAGCGATTTATGCGGCGCGCGC
CATGCTGAAACCCGTTGTCATTGCCGGTTTGCAGCAGGGCGGCCAGCTGATGATTACAACGGATGTGGAAAACTATCCGG
GCTATGCCGAGCCGGTGCAGGGGCCATGGATGATGGAGCAGATGGCCAGGCAGGCTGAAAATGTCGGTGCGCAAATCGTG
CATGACATCATCACCGAAGTTGAAACGACTGTGCGGCCGTTCCGTCTGAAGGGGGATTCCGGCACGATCTATACCTGCGA
TGCGCTTATTATCGCGACCGGTGCACAGGCCAAGTGGCTGGGGCTTGAAAGCGAGCAGACCTTCATGGGCGGCGGCGTTT
CGGCTTGTGCGACCTGCGACGGTTTCTTCTATCGCGGCAAGGATGTGGTTGTCGTCGGCGGCGGCAACACGGCTGTCGAA
GAGGCGCTTTATCTGTCGCATATTGCCAAAAGCGTCACGATCGTCCATCGCCGTGACGGTTTCCGTGCGGAAAAGATCAT
GCAGGATCGCCTGCTTTCGCGCGAGAACGTCTCGGTGGTGTGGAACAGTGTGATCGATGAAATCCTCGGCACCGAGGCCC
GGCCTCCGATGGGCGCGACCGTGACGGGTGTACGTCTGAAAAATATTGTCACCGGCGAAACGCAGGAACGCGCCACGCAT
GGCGTTTTCATCGCAATCGGCCACGCTCCGGCAGTTTCCTTGTTTGAGGGCAAGTTGAAACAGAAGCCAAACGGCTATTT
GTGGACCGCGCCCGATTCCACGGCTACCGATGTTCCCGGCATTTTCGCGGCGGGCGACGTGACGGACGACATTTACCGGC
AGGCTGTCACGGCTGCGGGCATGGGCTGCATGGCCGCGCTTGAGGCGGAACGCTGGCTGGCCGCACAGGAGCCGCTGCAC
GAAGCGGCGGAGTAG

Upstream 100 bases:

>100_bases
GCCACAGTGTTCGGGCATAGGCAAACAGCACGCGCGTACGATTCTTTCGAGCTGGGAGTGCGCGGCTTTAAATCGATTTT
AGGACCGGAGAGGAATCCTT

Downstream 100 bases:

>100_bases
AGCCTTCCGGCAAAAGTGCGAAGCGTTTTACGGAGGGTAAATGCGGTGAAAACAATGAGAGGGGAAAAACGTGGTCGCAC
CGCTTGACTGGGATAAACTG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTQRHAPVIVIGSGPAGYTAAIYAARAMLKPVVIAGLQQGGQLMITTDVENYPGYAEPVQGPWMMEQMARQAENVGAQIV
HDIITEVETTVRPFRLKGDSGTIYTCDALIIATGAQAKWLGLESEQTFMGGGVSACATCDGFFYRGKDVVVVGGGNTAVE
EALYLSHIAKSVTIVHRRDGFRAEKIMQDRLLSRENVSVVWNSVIDEILGTEARPPMGATVTGVRLKNIVTGETQERATH
GVFIAIGHAPAVSLFEGKLKQKPNGYLWTAPDSTATDVPGIFAAGDVTDDIYRQAVTAAGMGCMAALEAERWLAAQEPLH
EAAE

Sequences:

>Translated_324_residues
MTQRHAPVIVIGSGPAGYTAAIYAARAMLKPVVIAGLQQGGQLMITTDVENYPGYAEPVQGPWMMEQMARQAENVGAQIV
HDIITEVETTVRPFRLKGDSGTIYTCDALIIATGAQAKWLGLESEQTFMGGGVSACATCDGFFYRGKDVVVVGGGNTAVE
EALYLSHIAKSVTIVHRRDGFRAEKIMQDRLLSRENVSVVWNSVIDEILGTEARPPMGATVTGVRLKNIVTGETQERATH
GVFIAIGHAPAVSLFEGKLKQKPNGYLWTAPDSTATDVPGIFAAGDVTDDIYRQAVTAAGMGCMAALEAERWLAAQEPLH
EAAE
>Mature_323_residues
TQRHAPVIVIGSGPAGYTAAIYAARAMLKPVVIAGLQQGGQLMITTDVENYPGYAEPVQGPWMMEQMARQAENVGAQIVH
DIITEVETTVRPFRLKGDSGTIYTCDALIIATGAQAKWLGLESEQTFMGGGVSACATCDGFFYRGKDVVVVGGGNTAVEE
ALYLSHIAKSVTIVHRRDGFRAEKIMQDRLLSRENVSVVWNSVIDEILGTEARPPMGATVTGVRLKNIVTGETQERATHG
VFIAIGHAPAVSLFEGKLKQKPNGYLWTAPDSTATDVPGIFAAGDVTDDIYRQAVTAAGMGCMAALEAERWLAAQEPLHE
AAE

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=320, Percent_Identity=54.375, Blast_Score=344, Evalue=4e-96,
Organism=Escherichia coli, GI87081763, Length=321, Percent_Identity=30.2180685358255, Blast_Score=133, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6321898, Length=323, Percent_Identity=43.9628482972136, Blast_Score=273, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6320560, Length=323, Percent_Identity=40.8668730650155, Blast_Score=256, Evalue=3e-69,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34635; Mature: 34504

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRHAPVIVIGSGPAGYTAAIYAARAMLKPVVIAGLQQGGQLMITTDVENYPGYAEPVQ
CCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
GPWMMEQMARQAENVGAQIVHDIITEVETTVRPFRLKGDSGTIYTCDALIIATGAQAKWL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECEEEEECCCCEEEE
GLESEQTFMGGGVSACATCDGFFYRGKDVVVVGGGNTAVEEALYLSHIAKSVTIVHRRDG
CCCCCCEECCCCCHHHHHCCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCC
FRAEKIMQDRLLSRENVSVVWNSVIDEILGTEARPPMGATVTGVRLKNIVTGETQERATH
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECEEEEEEECCCCHHHCCC
GVFIAIGHAPAVSLFEGKLKQKPNGYLWTAPDSTATDVPGIFAAGDVTDDIYRQAVTAAG
CEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHC
MGCMAALEAERWLAAQEPLHEAAE
CHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQRHAPVIVIGSGPAGYTAAIYAARAMLKPVVIAGLQQGGQLMITTDVENYPGYAEPVQ
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
GPWMMEQMARQAENVGAQIVHDIITEVETTVRPFRLKGDSGTIYTCDALIIATGAQAKWL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECEEEEECCCCEEEE
GLESEQTFMGGGVSACATCDGFFYRGKDVVVVGGGNTAVEEALYLSHIAKSVTIVHRRDG
CCCCCCEECCCCCHHHHHCCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHEEEEECCCC
FRAEKIMQDRLLSRENVSVVWNSVIDEILGTEARPPMGATVTGVRLKNIVTGETQERATH
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECEEEEEEECCCCHHHCCC
GVFIAIGHAPAVSLFEGKLKQKPNGYLWTAPDSTATDVPGIFAAGDVTDDIYRQAVTAAG
CEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHC
MGCMAALEAERWLAAQEPLHEAAE
CHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]