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The map label for this gene is yoaE [H]

Identifier: 23502204

GI number: 23502204

Start: 1294243

End: 1295799

Strand: Reverse

Name: yoaE [H]

Synonym: BR1332

Alternate gene names: 23502204

Gene position: 1295799-1294243 (Counterclockwise)

Preceding gene: 23502205

Following gene: 23502203

Centisome position: 61.48

GC content: 58.9

Gene sequence:

>1557_bases
ATGGACTGGATTGCCGATCCCAACGCCTGGATAGGTTTGGTGACATTGGTGGTGCTCGAGATCGTTCTCGGTATCGACAA
TCTCGTCTTCATCGCCATTCTGGCCGACAAGCTGCCGCCGCACCAGCGCAATCGTGCGCGCCTGGTTGGCCTTGGTTTGG
CGCTTGTGATGCGTCTGGTGCTGCTCGCGTCGATCTCGTGGATCGTCACGCTGCGCGAACCGCTCATTTCCATAATGGGG
CTGTCGTTCTCCGGTCGCGATATCATCATGCTCACTGGCGGTCTGTTCCTGCTTGGCAAGGGCACGATGGAGCTTCATGA
ACGCCTTGAGGGCAGCCATGGACCGAAAAGCAGCCGGATTGTCCATGCGGTGTTCTGGCAGGTGATCGTGCAGATCGTGG
TGCTCGATGCCGTCTTCTCGCTCGACAGTGTGATCACGGCCGTAGGTATGGTCCAGCATCTGACGGTCATGATGATAGCC
GTCATTCTGGCCATCGGCGTGATGATGCTTGCCTCCCGACCCTTGATGGATTTCGTCAACAAGCATCCCACCGTCGTTAT
CCTCTGTCTCGGCTTCCTGATGATGATTGGTTTCAGTCTCGTTGCGGAAGGTTTCGGCTTGCATATTCCCAAGGGCTATC
TCTATGCGGCCATTGGCTTTTCGGTGCTTGTGGAGGCAGCCAACCAGTTTGCGCGCCGCAATCGCGAAAAGCTGGTGACG
ACAAACGACCTGCGCGAACGCACCGCAGGGGCCGTGCTGCGGCTTTTGGGCGGCAGCCGCGGTGAGAACCCGCTTTCCGA
CACGGTTGACGTGATTGCGCAGCAGATTGCGGCCAGCGATGTCTTCCTGCCGGAGGAAAAGGAAATGATCCGCGGTGTTC
TTGATCTGGCGGAGCGCCCGGTGCGGTCCATCATGTCGCCGCGCAACGAGGTGGAATGGCTCGATCTCGACGAGGATGAA
GACAAAATCCACGCCACTATCCGCAAGCTTTCGCATTCGCGGGTCGTGGTGGCGCGCCATCAGGTGGATGAGTTCATCGG
CGTGGCGCTGGTCAAGGATCTGCTGCTCGATATGACCGACAAGAAGGCCATCGACTGGGACAAGGTTGTGAAGCAGCCGC
TCGTTGTGCATGAGAATGCCAATGTGCTTCGTGTCATGGAGCAGTTGCGCATCTCGCCGATCCAGCTTGGCGTGGTCGTG
GACGAGCATGGCTCCTTCGAGGGTGTGGTGACGCCAACGGATATTCTGGAGGCCATCGCCGGGGAATTCCCGGATGAGGA
CGAGGAAGTCGCGGTCGCCCAATCCGACGGGCAGGGCGGTTATCTCGTGGATGGTTTTACGGATATTCGCCGCTTGAGCG
GACTTCTCGACCGCGATCTGGTGGACGAGGGTGATCGCTATACGACGCTTGCAGGCTATGTGCTCTGGCATCTCGGCCAT
TTGCCGGTTGGCGGCGAGAGTTTCACTGCCGACGGCTTTGATTTCACGATCGAGGCCATGAGCGGTCGCCACGTCGAGAA
GGTCCGGATCAGGCCCGTGCCGGATTACGAGGTGTAG

Upstream 100 bases:

>100_bases
ATCAATCTAACTATTTGTTTTGCCACACTATCCTACGCAAAACCGCCTTATGTTTTTGCTGGAATCATTCTAAAGGAGCC
GACATATCATGGACTGGTCC

Downstream 100 bases:

>100_bases
AACCTGTTTGCGGGCGGGGGCGCACTTCTCACAAATTATTTCACTCATTCATCTCCGATAGAATAAGTAGGTTATTGACA
AGGCCGGGGGGAAGCCTTCA

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MDWIADPNAWIGLVTLVVLEIVLGIDNLVFIAILADKLPPHQRNRARLVGLGLALVMRLVLLASISWIVTLREPLISIMG
LSFSGRDIIMLTGGLFLLGKGTMELHERLEGSHGPKSSRIVHAVFWQVIVQIVVLDAVFSLDSVITAVGMVQHLTVMMIA
VILAIGVMMLASRPLMDFVNKHPTVVILCLGFLMMIGFSLVAEGFGLHIPKGYLYAAIGFSVLVEAANQFARRNREKLVT
TNDLRERTAGAVLRLLGGSRGENPLSDTVDVIAQQIAASDVFLPEEKEMIRGVLDLAERPVRSIMSPRNEVEWLDLDEDE
DKIHATIRKLSHSRVVVARHQVDEFIGVALVKDLLLDMTDKKAIDWDKVVKQPLVVHENANVLRVMEQLRISPIQLGVVV
DEHGSFEGVVTPTDILEAIAGEFPDEDEEVAVAQSDGQGGYLVDGFTDIRRLSGLLDRDLVDEGDRYTTLAGYVLWHLGH
LPVGGESFTADGFDFTIEAMSGRHVEKVRIRPVPDYEV

Sequences:

>Translated_518_residues
MDWIADPNAWIGLVTLVVLEIVLGIDNLVFIAILADKLPPHQRNRARLVGLGLALVMRLVLLASISWIVTLREPLISIMG
LSFSGRDIIMLTGGLFLLGKGTMELHERLEGSHGPKSSRIVHAVFWQVIVQIVVLDAVFSLDSVITAVGMVQHLTVMMIA
VILAIGVMMLASRPLMDFVNKHPTVVILCLGFLMMIGFSLVAEGFGLHIPKGYLYAAIGFSVLVEAANQFARRNREKLVT
TNDLRERTAGAVLRLLGGSRGENPLSDTVDVIAQQIAASDVFLPEEKEMIRGVLDLAERPVRSIMSPRNEVEWLDLDEDE
DKIHATIRKLSHSRVVVARHQVDEFIGVALVKDLLLDMTDKKAIDWDKVVKQPLVVHENANVLRVMEQLRISPIQLGVVV
DEHGSFEGVVTPTDILEAIAGEFPDEDEEVAVAQSDGQGGYLVDGFTDIRRLSGLLDRDLVDEGDRYTTLAGYVLWHLGH
LPVGGESFTADGFDFTIEAMSGRHVEKVRIRPVPDYEV
>Mature_518_residues
MDWIADPNAWIGLVTLVVLEIVLGIDNLVFIAILADKLPPHQRNRARLVGLGLALVMRLVLLASISWIVTLREPLISIMG
LSFSGRDIIMLTGGLFLLGKGTMELHERLEGSHGPKSSRIVHAVFWQVIVQIVVLDAVFSLDSVITAVGMVQHLTVMMIA
VILAIGVMMLASRPLMDFVNKHPTVVILCLGFLMMIGFSLVAEGFGLHIPKGYLYAAIGFSVLVEAANQFARRNREKLVT
TNDLRERTAGAVLRLLGGSRGENPLSDTVDVIAQQIAASDVFLPEEKEMIRGVLDLAERPVRSIMSPRNEVEWLDLDEDE
DKIHATIRKLSHSRVVVARHQVDEFIGVALVKDLLLDMTDKKAIDWDKVVKQPLVVHENANVLRVMEQLRISPIQLGVVV
DEHGSFEGVVTPTDILEAIAGEFPDEDEEVAVAQSDGQGGYLVDGFTDIRRLSGLLDRDLVDEGDRYTTLAGYVLWHLGH
LPVGGESFTADGFDFTIEAMSGRHVEKVRIRPVPDYEV

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Escherichia coli, GI1788119, Length=510, Percent_Identity=50.9803921568627, Blast_Score=465, Evalue=1e-132,
Organism=Escherichia coli, GI87082033, Length=528, Percent_Identity=48.1060606060606, Blast_Score=448, Evalue=1e-127,
Organism=Escherichia coli, GI1789197, Length=235, Percent_Identity=51.4893617021277, Blast_Score=224, Evalue=8e-60,
Organism=Escherichia coli, GI1786879, Length=258, Percent_Identity=30.2325581395349, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790664, Length=251, Percent_Identity=23.9043824701195, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI145693175, Length=238, Percent_Identity=28.9915966386555, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005496
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF03741 TerC [H]

EC number: NA

Molecular weight: Translated: 57152; Mature: 57152

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWIADPNAWIGLVTLVVLEIVLGIDNLVFIAILADKLPPHQRNRARLVGLGLALVMRLV
CCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LLASISWIVTLREPLISIMGLSFSGRDIIMLTGGLFLLGKGTMELHERLEGSHGPKSSRI
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEECCHHHHHHHHCCCCCCCCHHH
VHAVFWQVIVQIVVLDAVFSLDSVITAVGMVQHLTVMMIAVILAIGVMMLASRPLMDFVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
KHPTVVILCLGFLMMIGFSLVAEGFGLHIPKGYLYAAIGFSVLVEAANQFARRNREKLVT
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
TNDLRERTAGAVLRLLGGSRGENPLSDTVDVIAQQIAASDVFLPEEKEMIRGVLDLAERP
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VRSIMSPRNEVEWLDLDEDEDKIHATIRKLSHSRVVVARHQVDEFIGVALVKDLLLDMTD
HHHHHCCCCCCCEECCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCC
KKAIDWDKVVKQPLVVHENANVLRVMEQLRISPIQLGVVVDEHGSFEGVVTPTDILEAIA
CCCCCHHHHHCCCEEEECCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHH
GEFPDEDEEVAVAQSDGQGGYLVDGFTDIRRLSGLLDRDLVDEGDRYTTLAGYVLWHLGH
CCCCCCCCCEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
LPVGGESFTADGFDFTIEAMSGRHVEKVRIRPVPDYEV
CCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MDWIADPNAWIGLVTLVVLEIVLGIDNLVFIAILADKLPPHQRNRARLVGLGLALVMRLV
CCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LLASISWIVTLREPLISIMGLSFSGRDIIMLTGGLFLLGKGTMELHERLEGSHGPKSSRI
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEECCHHHHHHHHCCCCCCCCHHH
VHAVFWQVIVQIVVLDAVFSLDSVITAVGMVQHLTVMMIAVILAIGVMMLASRPLMDFVN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHC
KHPTVVILCLGFLMMIGFSLVAEGFGLHIPKGYLYAAIGFSVLVEAANQFARRNREKLVT
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
TNDLRERTAGAVLRLLGGSRGENPLSDTVDVIAQQIAASDVFLPEEKEMIRGVLDLAERP
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VRSIMSPRNEVEWLDLDEDEDKIHATIRKLSHSRVVVARHQVDEFIGVALVKDLLLDMTD
HHHHHCCCCCCCEECCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHCCCC
KKAIDWDKVVKQPLVVHENANVLRVMEQLRISPIQLGVVVDEHGSFEGVVTPTDILEAIA
CCCCCHHHHHCCCEEEECCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHH
GEFPDEDEEVAVAQSDGQGGYLVDGFTDIRRLSGLLDRDLVDEGDRYTTLAGYVLWHLGH
CCCCCCCCCEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
LPVGGESFTADGFDFTIEAMSGRHVEKVRIRPVPDYEV
CCCCCCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]