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The map label for this gene is aatC [H]

Identifier: 23502151

GI number: 23502151

Start: 1237434

End: 1238654

Strand: Reverse

Name: aatC [H]

Synonym: BR1275

Alternate gene names: 23502151

Gene position: 1238654-1237434 (Counterclockwise)

Preceding gene: 23502152

Following gene: 23502150

Centisome position: 58.77

GC content: 58.64

Gene sequence:

>1221_bases
ATGTCGGAAGAATTCCATAAAATCCGTCGTCTGCCACCTTATGTCTTTGAACAGGTCAACCGTCTGAAGGCATCGGCGCG
AGCGGCGGGTGCCGACATTATCGATCTGGGCATGGGTAATCCCGATCTGCCGACCCCGCAAAATATCGTGGACAAGCTTT
GCGAGGCTGTGCAGGACCCGCGCGCCCATCGCTATTCCGCCTCCAAGGGCATTCCGGGCCTGCGCCGTGCTCAGGCACAA
TATTATGCACGCCGTTTTGGTGTGAAGCTTAACCCGGACACGCAGGTTGTCGCCACGCTTGGCTCCAAGGAAGGCTTCGC
CAATATGGCGCAGGCCATCACCGCGCCGGGCGATGTGGTTCTGTGCCCGGACCCGACCTATCCGATCCACTCCTTTGGCT
TCATCATGTCGGGCGGTGTCATTCGCTCGGTGCAGGCCAAGCCGGACGATAATTTCATCCCGACGCTTGAGCGCGGCGTG
AAACACTCCATTCCGAAGCCGATTGCGCTGATCCTCAATTTTCCGTCCAACCCGACGGCTTATGTGGCGACGCTTGATTT
CTACAAGGACGTGGTGGCTTTTGCGCGCAAGCACGACATCGTCATCCTTTCGGACCTGGCCTATTCGGAAATCTATTTCG
ACGGCAACCCGCCGCCATCCGTTCTGGAAGTGCCGGGCGCAATGGATGTGACGGTGGAGTTCACCTCCATGTCGAAGACT
TTCTCCATGCCCGGCTGGCGCATGGGCTTCGCGGTCGGCAATGAGCGTTTGATCGCCGCGCTGACGCGGGTGAAATCCTA
TCTCGATTATGGCGCCTTTACGCCGATCCAGGTGGCGGCGACGGCAGCACTCAATGGTGACGGCTCCGACATTGCCTATG
TGCGCAATGTCTATAAGCAGCGCCGTGACGTGCTGGTTGAAAGCTTCGGCCGCGCTGGCTGGGATGTTCCGCCACCGGCT
GCCACCATGTTTGCCTGGGTTCCGATCCCGGAACGGTTCCGCTCGCTGGGTTCGCTGGAATTCTCCAAACTTCTGGTGGA
GCAGGCCGATGTGGCTGTTGCGCCGGGCGTCGGTTTTGGTGAACATGGCGACGATTATGTGCGCATCGCGCTGGTGGAAA
ACGAGCATCGCATTCGTCAGGCCGCGCGCAATATCAAGCGGTTCTTTTCTGCCAAGGATGAGAACCTGCAAAATGTGATT
CCGCTTGAAGGTCACCGCTAG

Upstream 100 bases:

>100_bases
TTGGCCCGGTATCAAGTCTCGACCCGATTCGAGAACAGGTGTATAGCTCCTTCGCGGTGCGTGAGCGCCATTATATTCAA
CCCTCCTTTGGAACAGGATC

Downstream 100 bases:

>100_bases
ACGGCATTCCCACCTTTGCGGGCTGGCCCATGTTTGCAGGCTGGGCTATGCTTGCGGCCGCCCATGCTCGCGGGCTGGAT
TTATCCTGCCCGCAGTTCTC

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSEEFHKIRRLPPYVFEQVNRLKASARAAGADIIDLGMGNPDLPTPQNIVDKLCEAVQDPRAHRYSASKGIPGLRRAQAQ
YYARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVVLCPDPTYPIHSFGFIMSGGVIRSVQAKPDDNFIPTLERGV
KHSIPKPIALILNFPSNPTAYVATLDFYKDVVAFARKHDIVILSDLAYSEIYFDGNPPPSVLEVPGAMDVTVEFTSMSKT
FSMPGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATAALNGDGSDIAYVRNVYKQRRDVLVESFGRAGWDVPPPA
ATMFAWVPIPERFRSLGSLEFSKLLVEQADVAVAPGVGFGEHGDDYVRIALVENEHRIRQAARNIKRFFSAKDENLQNVI
PLEGHR

Sequences:

>Translated_406_residues
MSEEFHKIRRLPPYVFEQVNRLKASARAAGADIIDLGMGNPDLPTPQNIVDKLCEAVQDPRAHRYSASKGIPGLRRAQAQ
YYARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVVLCPDPTYPIHSFGFIMSGGVIRSVQAKPDDNFIPTLERGV
KHSIPKPIALILNFPSNPTAYVATLDFYKDVVAFARKHDIVILSDLAYSEIYFDGNPPPSVLEVPGAMDVTVEFTSMSKT
FSMPGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATAALNGDGSDIAYVRNVYKQRRDVLVESFGRAGWDVPPPA
ATMFAWVPIPERFRSLGSLEFSKLLVEQADVAVAPGVGFGEHGDDYVRIALVENEHRIRQAARNIKRFFSAKDENLQNVI
PLEGHR
>Mature_405_residues
SEEFHKIRRLPPYVFEQVNRLKASARAAGADIIDLGMGNPDLPTPQNIVDKLCEAVQDPRAHRYSASKGIPGLRRAQAQY
YARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVVLCPDPTYPIHSFGFIMSGGVIRSVQAKPDDNFIPTLERGVK
HSIPKPIALILNFPSNPTAYVATLDFYKDVVAFARKHDIVILSDLAYSEIYFDGNPPPSVLEVPGAMDVTVEFTSMSKTF
SMPGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATAALNGDGSDIAYVRNVYKQRRDVLVESFGRAGWDVPPPAA
TMFAWVPIPERFRSLGSLEFSKLLVEQADVAVAPGVGFGEHGDDYVRIALVENEHRIRQAARNIKRFFSAKDENLQNVIP
LEGHR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=23.2911392405063, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=23.2911392405063, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI56713256, Length=270, Percent_Identity=26.6666666666667, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI56713254, Length=300, Percent_Identity=26.3333333333333, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI169881281, Length=383, Percent_Identity=21.9321148825065, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1788722, Length=387, Percent_Identity=50.9043927648579, Blast_Score=420, Evalue=1e-119,
Organism=Escherichia coli, GI1786816, Length=386, Percent_Identity=26.4248704663212, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1788627, Length=393, Percent_Identity=25.1908396946565, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17567369, Length=401, Percent_Identity=23.1920199501247, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=269, Percent_Identity=26.7657992565056, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994476, Length=269, Percent_Identity=26.7657992565056, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17567663, Length=383, Percent_Identity=24.2819843342037, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322401, Length=398, Percent_Identity=24.3718592964824, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28573069, Length=389, Percent_Identity=25.4498714652956, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24646114, Length=389, Percent_Identity=25.4498714652956, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28573067, Length=389, Percent_Identity=25.4498714652956, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28573065, Length=389, Percent_Identity=25.4498714652956, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI18859735, Length=384, Percent_Identity=23.9583333333333, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44723; Mature: 44591

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEFHKIRRLPPYVFEQVNRLKASARAAGADIIDLGMGNPDLPTPQNIVDKLCEAVQDP
CCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCC
RAHRYSASKGIPGLRRAQAQYYARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVV
HHHHCCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCHHHHHHHHCCCCCEE
LCPDPTYPIHSFGFIMSGGVIRSVQAKPDDNFIPTLERGVKHSIPKPIALILNFPSNPTA
ECCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCE
YVATLDFYKDVVAFARKHDIVILSDLAYSEIYFDGNPPPSVLEVPGAMDVTVEFTSMSKT
EEEEHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCCEECCCCEEEEEEEECCCHH
FSMPGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATAALNGDGSDIAYVRNVYKQ
HCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHEEEEEECCCCCHHHHHHHHHHH
RRDVLVESFGRAGWDVPPPAATMFAWVPIPERFRSLGSLEFSKLLVEQADVAVAPGVGFG
HHHHHHHHHCCCCCCCCCCHHHEEEECCCHHHHHHHCCHHHHHHHHHHCCEEEECCCCCC
EHGDDYVRIALVENEHRIRQAARNIKRFFSAKDENLQNVIPLEGHR
CCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SEEFHKIRRLPPYVFEQVNRLKASARAAGADIIDLGMGNPDLPTPQNIVDKLCEAVQDP
CHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCC
RAHRYSASKGIPGLRRAQAQYYARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVV
HHHHCCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEEECCCCCCHHHHHHHHCCCCCEE
LCPDPTYPIHSFGFIMSGGVIRSVQAKPDDNFIPTLERGVKHSIPKPIALILNFPSNPTA
ECCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCE
YVATLDFYKDVVAFARKHDIVILSDLAYSEIYFDGNPPPSVLEVPGAMDVTVEFTSMSKT
EEEEHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCCEECCCCEEEEEEEECCCHH
FSMPGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATAALNGDGSDIAYVRNVYKQ
HCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHEEEEEECCCCCHHHHHHHHHHH
RRDVLVESFGRAGWDVPPPAATMFAWVPIPERFRSLGSLEFSKLLVEQADVAVAPGVGFG
HHHHHHHHHCCCCCCCCCCHHHEEEECCCHHHHHHHCCHHHHHHHHHHCCEEEECCCCCC
EHGDDYVRIALVENEHRIRQAARNIKRFFSAKDENLQNVIPLEGHR
CCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]