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The map label for this gene is murI

Identifier: 23502072

GI number: 23502072

Start: 1171030

End: 1171863

Strand: Reverse

Name: murI

Synonym: BR1195

Alternate gene names: 23502072

Gene position: 1171863-1171030 (Counterclockwise)

Preceding gene: 23502073

Following gene: 23502071

Centisome position: 55.6

GC content: 57.67

Gene sequence:

>834_bases
ATGAAAAAAGCACCTGCCGGCAGTTTTCCCGCGAAACCGACCATCGCTCCAGAAAGGCCAATTCTGGTCTTCGATAGCGG
TATTGGCGGCTTGACGGTCTTGCGCGAGGCACGCGTGGTGATGCCCGACCGGCGGTTCGTCTATATCGCCGACGATGCGG
GCTTTCCCTATGGCAACTGGGAGGAAGAAGCCCTGAAGCGCCGGATCATTGAGCTGTTTGGCGAATTCATTGCCAATTAT
GACCCCGAAATCGCGGTCATTGCCTGTAATACGGCTTCGACGCTGGTGCTGGAGGATTTGCGGCGCGCCTATCCCTCGGT
GCCCTTTGTCGGCACGGTGCCAGCCATAAAGCCTGCCGCCGAGCGAACCTCATCGGGGCTTGTTTCAGTACTTGCGACGC
CCGGCACGGTGAAGCGCGCCTATACGCGCGACCTGATCCAGTCTTTTGCATCGCGGTGCCATGTGCGTCTGGTGGGGGCC
GACGGGCTGGCGGCGATTGCCGAAGCGCACATTCGCGGTGAAAGTTTCGATGAGGCGCTGGTCATGGCGCAGATCGCGCC
ATGTTTTATCGAAAAGGATGGCAAGCGCACCGATATCGTGGTGCTTGCCTGTACGCATTATCCGTTTCTCGTCAATGTAT
TGCGCCGTCTGGCTCCATGGCCGGTGGATTGGCTGGACCCGGCGGAAGCCATTGCACGACGCATGAAATCGCTTTTGCCT
GCGCGAAGTGACGATGATGAATTTCATTCTCAAGATGACCTGGCATTCTTCACATCCAGGAAACCCGACTATGCCATTCG
CCGCCTGATGCAGGGTTTTGGGCTGCGTTTTTAA

Upstream 100 bases:

>100_bases
GCGTTGTTACCTCGCTCGACGTCTTTACGCCGAAGAAGCCGCGCGGCTCCGGTGCACCGGAAGGACGCGCGCGTAAACCT
GTCAATGAGGACAAGGCAGA

Downstream 100 bases:

>100_bases
TCGTTTCAGTCGACTCTGGCGGCGCTTGTCGGCAAGCGATTGTATTCTTTGGGAAAATCCAGAATAATGGAATGCGGTGG
TTGACAATCGGCCTCAAGCT

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MKKAPAGSFPAKPTIAPERPILVFDSGIGGLTVLREARVVMPDRRFVYIADDAGFPYGNWEEEALKRRIIELFGEFIANY
DPEIAVIACNTASTLVLEDLRRAYPSVPFVGTVPAIKPAAERTSSGLVSVLATPGTVKRAYTRDLIQSFASRCHVRLVGA
DGLAAIAEAHIRGESFDEALVMAQIAPCFIEKDGKRTDIVVLACTHYPFLVNVLRRLAPWPVDWLDPAEAIARRMKSLLP
ARSDDDEFHSQDDLAFFTSRKPDYAIRRLMQGFGLRF

Sequences:

>Translated_277_residues
MKKAPAGSFPAKPTIAPERPILVFDSGIGGLTVLREARVVMPDRRFVYIADDAGFPYGNWEEEALKRRIIELFGEFIANY
DPEIAVIACNTASTLVLEDLRRAYPSVPFVGTVPAIKPAAERTSSGLVSVLATPGTVKRAYTRDLIQSFASRCHVRLVGA
DGLAAIAEAHIRGESFDEALVMAQIAPCFIEKDGKRTDIVVLACTHYPFLVNVLRRLAPWPVDWLDPAEAIARRMKSLLP
ARSDDDEFHSQDDLAFFTSRKPDYAIRRLMQGFGLRF
>Mature_277_residues
MKKAPAGSFPAKPTIAPERPILVFDSGIGGLTVLREARVVMPDRRFVYIADDAGFPYGNWEEEALKRRIIELFGEFIANY
DPEIAVIACNTASTLVLEDLRRAYPSVPFVGTVPAIKPAAERTSSGLVSVLATPGTVKRAYTRDLIQSFASRCHVRLVGA
DGLAAIAEAHIRGESFDEALVMAQIAPCFIEKDGKRTDIVVLACTHYPFLVNVLRRLAPWPVDWLDPAEAIARRMKSLLP
ARSDDDEFHSQDDLAFFTSRKPDYAIRRLMQGFGLRF

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=246, Percent_Identity=39.0243902439024, Blast_Score=162, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_BRUA1 (B2S641)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935112.1
- ProteinModelPortal:   B2S641
- SMR:   B2S641
- GeneID:   6328681
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I11330
- HOGENOM:   HBG645102
- OMA:   CGHIPYG
- ProtClustDB:   PRK00865
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 30709; Mature: 30709

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAPAGSFPAKPTIAPERPILVFDSGIGGLTVLREARVVMPDRRFVYIADDAGFPYGNW
CCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCC
EEEALKRRIIELFGEFIANYDPEIAVIACNTASTLVLEDLRRAYPSVPFVGTVPAIKPAA
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
ERTSSGLVSVLATPGTVKRAYTRDLIQSFASRCHVRLVGADGLAAIAEAHIRGESFDEAL
HHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCHHHHH
VMAQIAPCFIEKDGKRTDIVVLACTHYPFLVNVLRRLAPWPVDWLDPAEAIARRMKSLLP
HHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
ARSDDDEFHSQDDLAFFTSRKPDYAIRRLMQGFGLRF
CCCCCHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKAPAGSFPAKPTIAPERPILVFDSGIGGLTVLREARVVMPDRRFVYIADDAGFPYGNW
CCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCC
EEEALKRRIIELFGEFIANYDPEIAVIACNTASTLVLEDLRRAYPSVPFVGTVPAIKPAA
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
ERTSSGLVSVLATPGTVKRAYTRDLIQSFASRCHVRLVGADGLAAIAEAHIRGESFDEAL
HHHHCCCEEEEECCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCHHHHH
VMAQIAPCFIEKDGKRTDIVVLACTHYPFLVNVLRRLAPWPVDWLDPAEAIARRMKSLLP
HHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
ARSDDDEFHSQDDLAFFTSRKPDYAIRRLMQGFGLRF
CCCCCHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA