Click here to switch to the map view.

The map label for this gene is frr

Identifier: 23502037

GI number: 23502037

Start: 1138936

End: 1139496

Strand: Reverse

Name: frr

Synonym: BR1159

Alternate gene names: 23502037

Gene position: 1139496-1138936 (Counterclockwise)

Preceding gene: 161486695

Following gene: 23502036

Centisome position: 54.06

GC content: 58.11

Gene sequence:

>561_bases
ATGAGCGATGCTTTTGACATCAACGACCTGAAACGCCGCATGGAGGGCGCTGTCAACGCATTGAAGCACGACCTTGGCGG
TCTGCGCACCGGGCGCGCTTCGGCAAGCTTGCTGGAGCCGATCACCATCGAAGCCTATGGCTCGACCATGCCGATCAATC
AGGTTGCCAATATCAGCGTACCGGAGTCGCGCATGCTGTCCGTCAGCGTGTGGGACAAGAGCATGGTCGGTGCGGTGGAG
CGTGCAATCCGCGATTCTGGCCTTGGTCTCAACCCGATCACCGACGGGATGACGTTGCGCATTCCCCTGCCGGAGCTGAA
CGAACAGCGCCGCAAGGAATTGGTCAAGATCGCGCATCAATATGCAGAGCAGGGGCGTATCGCTGCCCGCCATGTTCGCC
GCGACGGCATGGACCAGCTGAAAAAGCTGGAGAAGGACAGCGTAATCAGTCAGGATGAAAGCCGGGTTCTGTCCGAAAAG
GTACAGAAGCTGACCGACGATACCATCGCCGAGATGGATAAGATCGTTGCTGTCAAGGAGGGGGAGATCATGCAGGTTTA
G

Upstream 100 bases:

>100_bases
AAAACGGCGGCTTGGCCGATATTCTGCAAGGCAAGGGGCGTTGCACGATTGTTTCTGACAACTGATCGTGAACCTTGCTG
CGTATTGAAGGAGAAAATGC

Downstream 100 bases:

>100_bases
GCCCTGGGCCTGGCATTGCATGATTTTAAAAGGAGAGCTGCGCCATGTCCGATCCGCGCCACATAGCCATTATCATGGAT
GGCAACGGCCGTTGGGCTAA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSDAFDINDLKRRMEGAVNALKHDLGGLRTGRASASLLEPITIEAYGSTMPINQVANISVPESRMLSVSVWDKSMVGAVE
RAIRDSGLGLNPITDGMTLRIPLPELNEQRRKELVKIAHQYAEQGRIAARHVRRDGMDQLKKLEKDSVISQDESRVLSEK
VQKLTDDTIAEMDKIVAVKEGEIMQV

Sequences:

>Translated_186_residues
MSDAFDINDLKRRMEGAVNALKHDLGGLRTGRASASLLEPITIEAYGSTMPINQVANISVPESRMLSVSVWDKSMVGAVE
RAIRDSGLGLNPITDGMTLRIPLPELNEQRRKELVKIAHQYAEQGRIAARHVRRDGMDQLKKLEKDSVISQDESRVLSEK
VQKLTDDTIAEMDKIVAVKEGEIMQV
>Mature_185_residues
SDAFDINDLKRRMEGAVNALKHDLGGLRTGRASASLLEPITIEAYGSTMPINQVANISVPESRMLSVSVWDKSMVGAVER
AIRDSGLGLNPITDGMTLRIPLPELNEQRRKELVKIAHQYAEQGRIAARHVRRDGMDQLKKLEKDSVISQDESRVLSEKV
QKLTDDTIAEMDKIVAVKEGEIMQV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=184, Percent_Identity=30.4347826086957, Blast_Score=103, Evalue=8e-23,
Organism=Homo sapiens, GI291042689, Length=157, Percent_Identity=33.7579617834395, Blast_Score=94, Evalue=6e-20,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=47.2826086956522, Blast_Score=167, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24661488, Length=185, Percent_Identity=25.9459459459459, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_BRUA1 (B2S608)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935079.1
- ProteinModelPortal:   B2S608
- SMR:   B2S608
- GeneID:   6328647
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I10980
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20664; Mature: 20533

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAFDINDLKRRMEGAVNALKHDLGGLRTGRASASLLEPITIEAYGSTMPINQVANISV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCEEEEECCCCCCHHHHCCCCC
PESRMLSVSVWDKSMVGAVERAIRDSGLGLNPITDGMTLRIPLPELNEQRRKELVKIAHQ
CHHHEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
YAEQGRIAARHVRRDGMDQLKKLEKDSVISQDESRVLSEKVQKLTDDTIAEMDKIVAVKE
HHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GEIMQV
CCEECC
>Mature Secondary Structure 
SDAFDINDLKRRMEGAVNALKHDLGGLRTGRASASLLEPITIEAYGSTMPINQVANISV
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCEEEEECCCCCCHHHHCCCCC
PESRMLSVSVWDKSMVGAVERAIRDSGLGLNPITDGMTLRIPLPELNEQRRKELVKIAHQ
CHHHEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
YAEQGRIAARHVRRDGMDQLKKLEKDSVISQDESRVLSEKVQKLTDDTIAEMDKIVAVKE
HHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GEIMQV
CCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA