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The map label for this gene is uppS [H]

Identifier: 23502036

GI number: 23502036

Start: 1138127

End: 1138891

Strand: Reverse

Name: uppS [H]

Synonym: BR1158

Alternate gene names: 23502036

Gene position: 1138891-1138127 (Counterclockwise)

Preceding gene: 23502037

Following gene: 23502035

Centisome position: 54.03

GC content: 59.74

Gene sequence:

>765_bases
ATGTCCGATCCGCGCCACATAGCCATTATCATGGATGGCAACGGCCGTTGGGCTAAGGCGCGCGGCTTGCCGCGCAGCGC
GGGGCACCGCGCGGGCGTGGAGGCCTTGCGGGAGATCGTGCGGGCCGCGGGAGATCGCGGCCTCGGCTATCTTACGCTTT
TTGCTTTCTCTTCCGAAAACTGGACCCGTCCGAGCGGCGAGGTCAGCGATCTTCTGGGGCTTTTGAAGCTCTTCATCCGG
CGCGATCTGGCAGAGCTTCACCGCAACAATGTGCGTGTCAATATTATCGGCGAGCGGGCGGAGCTCGCAGCCGATATCCG
TGCACTGTTGAACGAAGCGGAATCGCTTACCCATCGCAATACCGGCCTCAATCTCGTGATTGCCTTCAATTACGGTTCAC
GCGATGAGATTGTTCGTGCGGTCAGAAGCCTTGCGCGCGATGTCGCCGCCGGGCTTCTTGATCCATCCTCGATCTCGGCG
GAGCTTGTTTCCGCTAATCTTGATACGGCGGGAATACCTGATCCCGACCTCATCATCCGCACCAGTGGCGAGATGCGGCT
TTCCAACTTTCTTCTCTGGCAGGCTGCCTATTCCGAGTTTCTCTTTCTGCCATGTCACTGGCCGGATTTCCGGCCGACCG
ACCTTGATGCGGCCTATGAAACGTTCCGGCAGCGCGAGCGTCGTTTTGGCGGTGTGGAGCCGCGCGCCAGTGCGGATGCC
GAAGAAGAAATATTATGCCCTTCGACCAAGGGAGCGGCAGTCTAG

Upstream 100 bases:

>100_bases
TCGCCGAGATGGATAAGATCGTTGCTGTCAAGGAGGGGGAGATCATGCAGGTTTAGGCCCTGGGCCTGGCATTGCATGAT
TTTAAAAGGAGAGCTGCGCC

Downstream 100 bases:

>100_bases
AGTGGTTCCCGTTTTAACAGAATCGCCGGAACCGCTCTCAGTGATGCGAATTTCAGATAAGCCATACTAGCGCGCTATAA
GTGTCGTTCCGCCGAAAGGT

Product: undecaprenyl pyrophosphate synthase

Products: NA

Alternate protein names: UPP synthase; Di-trans,poly-cis-decaprenylcistransferase; Undecaprenyl diphosphate synthase; UDS [H]

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MSDPRHIAIIMDGNGRWAKARGLPRSAGHRAGVEALREIVRAAGDRGLGYLTLFAFSSENWTRPSGEVSDLLGLLKLFIR
RDLAELHRNNVRVNIIGERAELAADIRALLNEAESLTHRNTGLNLVIAFNYGSRDEIVRAVRSLARDVAAGLLDPSSISA
ELVSANLDTAGIPDPDLIIRTSGEMRLSNFLLWQAAYSEFLFLPCHWPDFRPTDLDAAYETFRQRERRFGGVEPRASADA
EEEILCPSTKGAAV

Sequences:

>Translated_254_residues
MSDPRHIAIIMDGNGRWAKARGLPRSAGHRAGVEALREIVRAAGDRGLGYLTLFAFSSENWTRPSGEVSDLLGLLKLFIR
RDLAELHRNNVRVNIIGERAELAADIRALLNEAESLTHRNTGLNLVIAFNYGSRDEIVRAVRSLARDVAAGLLDPSSISA
ELVSANLDTAGIPDPDLIIRTSGEMRLSNFLLWQAAYSEFLFLPCHWPDFRPTDLDAAYETFRQRERRFGGVEPRASADA
EEEILCPSTKGAAV
>Mature_253_residues
SDPRHIAIIMDGNGRWAKARGLPRSAGHRAGVEALREIVRAAGDRGLGYLTLFAFSSENWTRPSGEVSDLLGLLKLFIRR
DLAELHRNNVRVNIIGERAELAADIRALLNEAESLTHRNTGLNLVIAFNYGSRDEIVRAVRSLARDVAAGLLDPSSISAE
LVSANLDTAGIPDPDLIIRTSGEMRLSNFLLWQAAYSEFLFLPCHWPDFRPTDLDAAYETFRQRERRFGGVEPRASADAE
EEILCPSTKGAAV

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI45580738, Length=223, Percent_Identity=39.9103139013453, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI45580742, Length=223, Percent_Identity=39.9103139013453, Blast_Score=159, Evalue=3e-39,
Organism=Escherichia coli, GI1786371, Length=230, Percent_Identity=48.2608695652174, Blast_Score=223, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI71993029, Length=228, Percent_Identity=34.6491228070175, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319474, Length=215, Percent_Identity=36.2790697674419, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6323748, Length=215, Percent_Identity=29.7674418604651, Blast_Score=98, Evalue=1e-21,
Organism=Drosophila melanogaster, GI18857969, Length=208, Percent_Identity=38.9423076923077, Blast_Score=134, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 28036; Mature: 27905

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS01066 UPP_SYNTHETASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPRHIAIIMDGNGRWAKARGLPRSAGHRAGVEALREIVRAAGDRGLGYLTLFAFSSEN
CCCCEEEEEEECCCCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCC
WTRPSGEVSDLLGLLKLFIRRDLAELHRNNVRVNIIGERAELAADIRALLNEAESLTHRN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCC
TGLNLVIAFNYGSRDEIVRAVRSLARDVAAGLLDPSSISAELVSANLDTAGIPDPDLIIR
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEE
TSGEMRLSNFLLWQAAYSEFLFLPCHWPDFRPTDLDAAYETFRQRERRFGGVEPRASADA
CCCCHHHHHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
EEEILCPSTKGAAV
CCCEECCCCCCCCC
>Mature Secondary Structure 
SDPRHIAIIMDGNGRWAKARGLPRSAGHRAGVEALREIVRAAGDRGLGYLTLFAFSSEN
CCCEEEEEEECCCCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCC
WTRPSGEVSDLLGLLKLFIRRDLAELHRNNVRVNIIGERAELAADIRALLNEAESLTHRN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCC
TGLNLVIAFNYGSRDEIVRAVRSLARDVAAGLLDPSSISAELVSANLDTAGIPDPDLIIR
CCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCEEEE
TSGEMRLSNFLLWQAAYSEFLFLPCHWPDFRPTDLDAAYETFRQRERRFGGVEPRASADA
CCCCHHHHHHHHHHHHHHCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
EEEILCPSTKGAAV
CCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA