Click here to switch to the map view.

The map label for this gene is fabZ [H]

Identifier: 23502030

GI number: 23502030

Start: 1131748

End: 1132221

Strand: Reverse

Name: fabZ [H]

Synonym: BR1152

Alternate gene names: 23502030

Gene position: 1132221-1131748 (Counterclockwise)

Preceding gene: 23502031

Following gene: 23502029

Centisome position: 53.72

GC content: 54.01

Gene sequence:

>474_bases
ATGAGTGATGACAATCAGACCAAGTTGGAAGCCGCGGATATTCAGGCACTCCTGGCTGTGCTTCCGCATCGTTATCCCTT
TTTGCTGATTGACCGCATTGTGGATATCGATGGTGACGTATCGGCGACTGGTATCAAGAACGTGACCATCAATGAACCAC
ATTTTACTGGCCATTTCCCCGAAAATCCGATCATGCCGGGTGTGCTGATTGTCGAAGCCATGGCCCAGACCGCTGGCGCG
ATCTCGCTCCTGCAACGCAAGACCGGTCGCCCCGGCGTCGTCTATTTCATGACGATCGATAATGCCAAGTTCCGCCGCCC
GGTGGTTCCGGGCGATCGTCTGCTGTTGCATGTGAAGAAGATCAAGCAGCGGGCGAATATTTCCAAGTATGAATGCGTGG
CCGAAGTCGATGGCGTAAAGGTTGCCGAAGCTGAAGTCGCTGCCATGATCAGCGTAGCTGACGAGAACCTGTGA

Upstream 100 bases:

>100_bases
GAGCGTTGGGGGGGCATCCCTGCGCGGCCTATCAAGCAGTGGTTCCGCGATATTGCGAACATCCGCAGCATCGGGCAATC
AAGAAAGGACGCATCCTCTG

Downstream 100 bases:

>100_bases
GTAAATCGATGAAGGAAACATTCATTCACCCCACAGCCTTGGTTGAACCGGGTGTGGAGCTGGGGCAGGGCGTGTCCGTG
GGGCCGTTCTGCCATGTCCA

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 157; Mature: 156

Protein sequence:

>157_residues
MSDDNQTKLEAADIQALLAVLPHRYPFLLIDRIVDIDGDVSATGIKNVTINEPHFTGHFPENPIMPGVLIVEAMAQTAGA
ISLLQRKTGRPGVVYFMTIDNAKFRRPVVPGDRLLLHVKKIKQRANISKYECVAEVDGVKVAEAEVAAMISVADENL

Sequences:

>Translated_157_residues
MSDDNQTKLEAADIQALLAVLPHRYPFLLIDRIVDIDGDVSATGIKNVTINEPHFTGHFPENPIMPGVLIVEAMAQTAGA
ISLLQRKTGRPGVVYFMTIDNAKFRRPVVPGDRLLLHVKKIKQRANISKYECVAEVDGVKVAEAEVAAMISVADENL
>Mature_156_residues
SDDNQTKLEAADIQALLAVLPHRYPFLLIDRIVDIDGDVSATGIKNVTINEPHFTGHFPENPIMPGVLIVEAMAQTAGAI
SLLQRKTGRPGVVYFMTIDNAKFRRPVVPGDRLLLHVKKIKQRANISKYECVAEVDGVKVAEAEVAAMISVADENL

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=139, Percent_Identity=46.0431654676259, Blast_Score=135, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 17188; Mature: 17057

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDNQTKLEAADIQALLAVLPHRYPFLLIDRIVDIDGDVSATGIKNVTINEPHFTGHFP
CCCCCCCCHHHHHHHHHHHHHCCCCCHHEEHHHHCCCCCCCCCCCCEEEECCCCCCCCCC
ENPIMPGVLIVEAMAQTAGAISLLQRKTGRPGVVYFMTIDNAKFRRPVVPGDRLLLHVKK
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
IKQRANISKYECVAEVDGVKVAEAEVAAMISVADENL
HHHHCCCCHHHHHHHCCCCEEHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SDDNQTKLEAADIQALLAVLPHRYPFLLIDRIVDIDGDVSATGIKNVTINEPHFTGHFP
CCCCCCCHHHHHHHHHHHHHCCCCCHHEEHHHHCCCCCCCCCCCCEEEECCCCCCCCCC
ENPIMPGVLIVEAMAQTAGAISLLQRKTGRPGVVYFMTIDNAKFRRPVVPGDRLLLHVKK
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHH
IKQRANISKYECVAEVDGVKVAEAEVAAMISVADENL
HHHHCCCCHHHHHHHCCCCEEHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA