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The map label for this gene is pqqL [C]

Identifier: 23501384

GI number: 23501384

Start: 481424

End: 482716

Strand: Reverse

Name: pqqL [C]

Synonym: BR0483

Alternate gene names: 23501384

Gene position: 482716-481424 (Counterclockwise)

Preceding gene: 23501385

Following gene: 23501383

Centisome position: 22.9

GC content: 59.01

Gene sequence:

>1293_bases
ATGGGTGTTGAAGTAACGCGTCTTCCCAACGGGTTGACAATAGCCACCGATACCATGCCGCATGTTGAAAGCGTGGCGTT
GGGAATCTGGGTAAAGGTGGGAGCGCGTAACGAAGCCCCCGACCGTCACGGAATTGCGCATCTTCTGGAGCATATGGCTT
TCAAGGGCACGGAAAACCGTACAGCCTGGCAGATCGCATCGGACATTGAAAATGTGGGTGGCGAGATCAACGCCGCCACC
AGCGTGGAGACCACCTCCTATTATGCCCGCGTGCTGCGCAACGATATGCCGCTGGCCATCGACATTCTTTCCGATATCCT
GACCGCCTCCAAATTCGACGAGGGCGAGCTGGAACGCGAAAAGCAGGTCATCATGCAGGAGATCGGCGCGGCGCACGATA
CGCCCGACGATATCGTCTTCGACCGTTTCACCGAAACCGCCTATCGCCACCAGCCCATCGGCCGCGCGATCCTGGGCGAG
CCGGAAACGGTGATGTCATTCACATCCGACGACCTGCGCCAATATATGCAGGAGCAATATAGCGTCGACCGCATGGTGGT
GACGGCGGCTGGCGGCATCGACCATGACGAATTCGTGCGCGAGGTTGAAAAGCGGCTCGGCAGTTTCCGTCCGCACAATA
CCGCGCCAACACTCGACCTTGCTCATTATGTCGGCGGCGATTTCCGCGAAAACCGCGAATTGATGGATGCGCAGGTGCTG
ATCGGTTTTGAAGGCCGCGCCTATCATGTGCGCGACTTCTACGCTTCGCAGCTTCTTTCGATGATCCTCGGCGGCGGCAT
GTCCTCGCGGCTTTTCCAGGAAGTGCGCGAAAAGCGCGGGCTTTGCTATTCGGTCTATGCCTTCCATTGGGGCTTTTCCG
ATACGGGGCTGTTTGGCATCCATGCCGCAACGGGGCGCGACGAGCTTGTGGAACTCGTGCCGGTCATTATCGACGAATTG
CACAAGGCAGCCGATTCCATCGGCATCGAGGAAGTGGACCGCGCCCGTGCGCAATATCGCGCAAGCCTCCTCATGTCGCA
GGAAAGCGCGGCAAGCCGTGCGGGCCAGATTGCGCGCCAGTTCCTGCTCTATGGACGCCCGGTGGAAAACAGCGAATTGC
TGGACCGCCTGTCCCTCATCACCCCGGAACGCCTGACCGACCTTGCCGGACGGCTTTTCCTCAACAACAAACCAACCATC
GCAGGCGTCGGTCCCGTTGGCTGCCTCATGAGCTTCGATCGCCTGACCGATGCGCTTTCGACCAATGCGCATACGAGGAA
GATAGCTGTCTAG

Upstream 100 bases:

>100_bases
AGCTGAAAATCGTGGAAGAATATGTGCGCCACCATTCCCGAGCCTGAATAGAGCAGGCACGAAAGGGAACCAGGGTGAGA
ATGCAGGGAGCAATTTGCTA

Downstream 100 bases:

>100_bases
AGCATTTTCGAGCCAAAAGTGCGAAGCGGCTTTGCGTCGGATAATGCGTCAAAACAAAGAGATAGAACAATAGGGCAGTA
AGGGAGTTAGGGCAGTATGT

Product: processing protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MGVEVTRLPNGLTIATDTMPHVESVALGIWVKVGARNEAPDRHGIAHLLEHMAFKGTENRTAWQIASDIENVGGEINAAT
SVETTSYYARVLRNDMPLAIDILSDILTASKFDEGELEREKQVIMQEIGAAHDTPDDIVFDRFTETAYRHQPIGRAILGE
PETVMSFTSDDLRQYMQEQYSVDRMVVTAAGGIDHDEFVREVEKRLGSFRPHNTAPTLDLAHYVGGDFRENRELMDAQVL
IGFEGRAYHVRDFYASQLLSMILGGGMSSRLFQEVREKRGLCYSVYAFHWGFSDTGLFGIHAATGRDELVELVPVIIDEL
HKAADSIGIEEVDRARAQYRASLLMSQESAASRAGQIARQFLLYGRPVENSELLDRLSLITPERLTDLAGRLFLNNKPTI
AGVGPVGCLMSFDRLTDALSTNAHTRKIAV

Sequences:

>Translated_430_residues
MGVEVTRLPNGLTIATDTMPHVESVALGIWVKVGARNEAPDRHGIAHLLEHMAFKGTENRTAWQIASDIENVGGEINAAT
SVETTSYYARVLRNDMPLAIDILSDILTASKFDEGELEREKQVIMQEIGAAHDTPDDIVFDRFTETAYRHQPIGRAILGE
PETVMSFTSDDLRQYMQEQYSVDRMVVTAAGGIDHDEFVREVEKRLGSFRPHNTAPTLDLAHYVGGDFRENRELMDAQVL
IGFEGRAYHVRDFYASQLLSMILGGGMSSRLFQEVREKRGLCYSVYAFHWGFSDTGLFGIHAATGRDELVELVPVIIDEL
HKAADSIGIEEVDRARAQYRASLLMSQESAASRAGQIARQFLLYGRPVENSELLDRLSLITPERLTDLAGRLFLNNKPTI
AGVGPVGCLMSFDRLTDALSTNAHTRKIAV
>Mature_429_residues
GVEVTRLPNGLTIATDTMPHVESVALGIWVKVGARNEAPDRHGIAHLLEHMAFKGTENRTAWQIASDIENVGGEINAATS
VETTSYYARVLRNDMPLAIDILSDILTASKFDEGELEREKQVIMQEIGAAHDTPDDIVFDRFTETAYRHQPIGRAILGEP
ETVMSFTSDDLRQYMQEQYSVDRMVVTAAGGIDHDEFVREVEKRLGSFRPHNTAPTLDLAHYVGGDFRENRELMDAQVLI
GFEGRAYHVRDFYASQLLSMILGGGMSSRLFQEVREKRGLCYSVYAFHWGFSDTGLFGIHAATGRDELVELVPVIIDELH
KAADSIGIEEVDRARAQYRASLLMSQESAASRAGQIARQFLLYGRPVENSELLDRLSLITPERLTDLAGRLFLNNKPTIA
GVGPVGCLMSFDRLTDALSTNAHTRKIAV

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=423, Percent_Identity=32.1513002364066, Blast_Score=228, Evalue=7e-60,
Organism=Homo sapiens, GI46593007, Length=429, Percent_Identity=27.972027972028, Blast_Score=205, Evalue=6e-53,
Organism=Homo sapiens, GI24308013, Length=449, Percent_Identity=26.0579064587973, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI50592988, Length=421, Percent_Identity=24.4655581947743, Blast_Score=112, Evalue=9e-25,
Organism=Escherichia coli, GI1787770, Length=219, Percent_Identity=26.4840182648402, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71999683, Length=414, Percent_Identity=30.6763285024155, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17553678, Length=416, Percent_Identity=24.5192307692308, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17510601, Length=455, Percent_Identity=24.6153846153846, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17570205, Length=415, Percent_Identity=20.4819277108434, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32566323, Length=415, Percent_Identity=20.4819277108434, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569737, Length=339, Percent_Identity=21.8289085545723, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=418, Percent_Identity=34.4497607655502, Blast_Score=244, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6321813, Length=435, Percent_Identity=27.5862068965517, Blast_Score=152, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6319426, Length=438, Percent_Identity=22.1461187214612, Blast_Score=106, Evalue=8e-24,
Organism=Drosophila melanogaster, GI21357875, Length=427, Percent_Identity=29.7423887587822, Blast_Score=228, Evalue=7e-60,
Organism=Drosophila melanogaster, GI24646943, Length=427, Percent_Identity=29.7423887587822, Blast_Score=228, Evalue=7e-60,
Organism=Drosophila melanogaster, GI19921772, Length=455, Percent_Identity=25.7142857142857, Blast_Score=141, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24665395, Length=429, Percent_Identity=24.2424242424242, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47799; Mature: 47667

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVEVTRLPNGLTIATDTMPHVESVALGIWVKVGARNEAPDRHGIAHLLEHMAFKGTENR
CCCEEEECCCCCEEEECCCCHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
TAWQIASDIENVGGEINAATSVETTSYYARVLRNDMPLAIDILSDILTASKFDEGELERE
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHH
KQVIMQEIGAAHDTPDDIVFDRFTETAYRHQPIGRAILGEPETVMSFTSDDLRQYMQEQY
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHCCHHHHHHHHHHHH
SVDRMVVTAAGGIDHDEFVREVEKRLGSFRPHNTAPTLDLAHYVGGDFRENRELMDAQVL
CCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCHHHCHHHHCEEEE
IGFEGRAYHVRDFYASQLLSMILGGGMSSRLFQEVREKRGLCYSVYAFHWGFSDTGLFGI
EECCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEE
HAATGRDELVELVPVIIDELHKAADSIGIEEVDRARAQYRASLLMSQESAASRAGQIARQ
EECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLYGRPVENSELLDRLSLITPERLTDLAGRLFLNNKPTIAGVGPVGCLMSFDRLTDALS
HHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHEECCCCCEECCCHHHHHHHHHHHHHHHH
TNAHTRKIAV
CCCCCEEECC
>Mature Secondary Structure 
GVEVTRLPNGLTIATDTMPHVESVALGIWVKVGARNEAPDRHGIAHLLEHMAFKGTENR
CCEEEECCCCCEEEECCCCHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCC
TAWQIASDIENVGGEINAATSVETTSYYARVLRNDMPLAIDILSDILTASKFDEGELERE
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHH
KQVIMQEIGAAHDTPDDIVFDRFTETAYRHQPIGRAILGEPETVMSFTSDDLRQYMQEQY
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHCCHHHHHHHHHHHH
SVDRMVVTAAGGIDHDEFVREVEKRLGSFRPHNTAPTLDLAHYVGGDFRENRELMDAQVL
CCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCHHHCHHHHCEEEE
IGFEGRAYHVRDFYASQLLSMILGGGMSSRLFQEVREKRGLCYSVYAFHWGFSDTGLFGI
EECCCCEEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEE
HAATGRDELVELVPVIIDELHKAADSIGIEEVDRARAQYRASLLMSQESAASRAGQIARQ
EECCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLYGRPVENSELLDRLSLITPERLTDLAGRLFLNNKPTIAGVGPVGCLMSFDRLTDALS
HHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHEECCCCCEECCCHHHHHHHHHHHHHHHH
TNAHTRKIAV
CCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA