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The map label for this gene is maeN [H]

Identifier: 23100672

GI number: 23100672

Start: 3349135

End: 3350451

Strand: Reverse

Name: maeN [H]

Synonym: OB3217

Alternate gene names: 23100672

Gene position: 3350451-3349135 (Counterclockwise)

Preceding gene: 23100673

Following gene: 23100671

Centisome position: 92.29

GC content: 39.1

Gene sequence:

>1317_bases
ATGAAAGAATCTACAGAAATGAAAACGAATACAACAAAAGATAATACAGTTTCCCTTCCACAGTCCGGAGTGAAAATATT
TGGAATGCCGGTTTTATGGTTTCTACTATTTTCAGCAATAACGATTATTGCTATCTATTCTGGTAGTCTTCCAGCAGGTA
TGATTGGTAGTTTACTTGTTATGATTGTTATCGGTGAACTACTAGGTTTCGTAGGAGATAGAACACCTATTGTACGTACT
TTTCTAGGCGGAGGAGCAATTGTGGCGATATTTGGTTCCGCATTTATGGTGTATAGCGGTATATTGCCAGAGTATGTGGT
AACGGGTGTTACCGACTTTATGACAACAGGCGGTTTTCTTGATTTTTATATTGCAGCACTTATTACTGGAAGTATTTTAG
GAATGAGCTCCAAGCTATTAGTAAAAGTAGGTATCCGTTTCTTTGTTCCCATCGTCGGAGCAATCGTCGGTGCGGTTATT
TTAGCATCAATCATTGGTAGCATTGTAGGATTTACGGTCCAAGATGCAATTCTTGTCTTAACATTGCCTATTATGGGTGG
AGGCATGGGAGCAGGTGCTGTTCCGATGAGTCAAATTTATTCAGAGCTATTAGGTAATAGTCCAAGTTATTATATTTCCA
TGTTAGTACCTGCGCTAGCATTAGGAAATGTCTTTGCGATTGTTTTAGCGAGTATACTAAATTTAATCGGGAAAAAATAT
CCTTCTTTAACAGGGAACGGACAAATTATTGAAGGCGTAACTCAGGATACGAAGGAACAAAAATATGATATTAAATTAAT
GGGAGCAGGGTTGCTTGCAGCAATTGCCTTCTTTACGATCGGTTCTGTGTTAGGTGATTTCTTACCCATTCATGCGTATG
CTATTATGATTATCTTAGTAGCCTTAACTAAAATTGCGAATATCTTACCACAAACCGTTTTAGACGGAGCAAGTCAGTGG
TATCAGTTCGTAGCTAGTAACTGGACATTAGCACTTCTATTCGGAATCGGGGTTGCGTATACTGATTTAAATACAGTAAT
CGAAGCATTAACGCTTCAATATATTCTAACTGTCTTTGCGGTGGTATTAGGAGCAATCCTAGGTGCAGGATTACTCGGTA
AACTCGTAGGATTCTATCCAATTGAGGCAGCTATTACAGGTGGATTGTGTATGGCCAACATGGGAGGTACGGGAGATGTA
GCAGTATTATCAGCTTCCAAACGTATGGAATTAATGCCATTCGCTCAAATCTCCTCTCGCTTAGGTGGGGCAATTATACT
GCTCATTACTGGCTTAATCATACAAATGTTCTTATAG

Upstream 100 bases:

>100_bases
GAAACAAGCTCTGTAAGTTAATGTAAGAGGGGGAAGAGCCTTCCTTCTAATTTTGAGGAAGGCTCTTCAAAAATAAAACC
GAAAGAGAAAGGTGAACAAA

Downstream 100 bases:

>100_bases
ACAGCATTACTAAAAAAGCTTTTATTGTGAGAAAAAATCACAATAAAAGCTTTTTTGTTTAGGAAAGGAAAGAAAGTATC
ACGAATGAGGGCCCTTATCT

Product: sodium:citrate symporter

Products: NA

Alternate protein names: Sodium-dependent malate transporter [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MKESTEMKTNTTKDNTVSLPQSGVKIFGMPVLWFLLFSAITIIAIYSGSLPAGMIGSLLVMIVIGELLGFVGDRTPIVRT
FLGGGAIVAIFGSAFMVYSGILPEYVVTGVTDFMTTGGFLDFYIAALITGSILGMSSKLLVKVGIRFFVPIVGAIVGAVI
LASIIGSIVGFTVQDAILVLTLPIMGGGMGAGAVPMSQIYSELLGNSPSYYISMLVPALALGNVFAIVLASILNLIGKKY
PSLTGNGQIIEGVTQDTKEQKYDIKLMGAGLLAAIAFFTIGSVLGDFLPIHAYAIMIILVALTKIANILPQTVLDGASQW
YQFVASNWTLALLFGIGVAYTDLNTVIEALTLQYILTVFAVVLGAILGAGLLGKLVGFYPIEAAITGGLCMANMGGTGDV
AVLSASKRMELMPFAQISSRLGGAIILLITGLIIQMFL

Sequences:

>Translated_438_residues
MKESTEMKTNTTKDNTVSLPQSGVKIFGMPVLWFLLFSAITIIAIYSGSLPAGMIGSLLVMIVIGELLGFVGDRTPIVRT
FLGGGAIVAIFGSAFMVYSGILPEYVVTGVTDFMTTGGFLDFYIAALITGSILGMSSKLLVKVGIRFFVPIVGAIVGAVI
LASIIGSIVGFTVQDAILVLTLPIMGGGMGAGAVPMSQIYSELLGNSPSYYISMLVPALALGNVFAIVLASILNLIGKKY
PSLTGNGQIIEGVTQDTKEQKYDIKLMGAGLLAAIAFFTIGSVLGDFLPIHAYAIMIILVALTKIANILPQTVLDGASQW
YQFVASNWTLALLFGIGVAYTDLNTVIEALTLQYILTVFAVVLGAILGAGLLGKLVGFYPIEAAITGGLCMANMGGTGDV
AVLSASKRMELMPFAQISSRLGGAIILLITGLIIQMFL
>Mature_438_residues
MKESTEMKTNTTKDNTVSLPQSGVKIFGMPVLWFLLFSAITIIAIYSGSLPAGMIGSLLVMIVIGELLGFVGDRTPIVRT
FLGGGAIVAIFGSAFMVYSGILPEYVVTGVTDFMTTGGFLDFYIAALITGSILGMSSKLLVKVGIRFFVPIVGAIVGAVI
LASIIGSIVGFTVQDAILVLTLPIMGGGMGAGAVPMSQIYSELLGNSPSYYISMLVPALALGNVFAIVLASILNLIGKKY
PSLTGNGQIIEGVTQDTKEQKYDIKLMGAGLLAAIAFFTIGSVLGDFLPIHAYAIMIILVALTKIANILPQTVLDGASQW
YQFVASNWTLALLFGIGVAYTDLNTVIEALTLQYILTVFAVVLGAILGAGLLGKLVGFYPIEAAITGGLCMANMGGTGDV
AVLSASKRMELMPFAQISSRLGGAIILLITGLIIQMFL

Specific function: Acts as a Na(+)-malate symporter, as it catalyzes malate-dependent uptake of Na(+) and Na(+)-dependent uptake of malate [H]

COG id: COG3493

COG function: function code C; Na+/citrate symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:citrate (SCF) symporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004679
- InterPro:   IPR018025 [H]

Pfam domain/function: PF03390 2HCT [H]

EC number: NA

Molecular weight: Translated: 45828; Mature: 45828

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCHHHHHHHHHHHHHHHC
>Mature Secondary Structure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HCHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 10903309; 12949159 [H]