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The map label for this gene is nrdF [H]

Identifier: 23100542

GI number: 23100542

Start: 3210304

End: 3211347

Strand: Reverse

Name: nrdF [H]

Synonym: OB3087

Alternate gene names: 23100542

Gene position: 3211347-3210304 (Counterclockwise)

Preceding gene: 23100543

Following gene: 23100536

Centisome position: 88.45

GC content: 33.91

Gene sequence:

>1044_bases
ATGCAAAAAGTTATGCTTGAGAAAGCAAAAACATTAGAGCCTAGAAATCCAAATAAGTCCACAAAGCTATTTGGTGGGGA
ATCAAGCGGAATCTTAAATTGGAATGATATTGCTTATCCACATTGGTATAAAATGTACAAACGACTCGTAGGAAACTACT
GGCAAGCAGATGAAGTAAATATGTCTAGTGATGTTAAGCAGTTTTCCACATTAAGTAAAGAAGAACAAGATGCGTACCTA
AAAATAATAGGACTGTTATCCACATTGGATGCGCCACAAACAAGAACAGCTTTACTAATATCTTTATATGCAACTGATCC
TTCTGTTCAATCTATTATGGCAGTAATAGCACAGCAAGAGGCAGTTCATAATGAAAGTTATTCTTACGTATTATCTTCTG
TTGTTTCTTGGAATGAACAGAATGAAGCATTTCAATTAGGAAGAACAGATGAATTATTGTTAAAAAGAAATGAACAGCTA
ACCGAACAATACAATGCGTTTGTGGATAATCCAAGTATGGAAAACATGCTTAAAACACTTGTGTATACTTCTCTACTAGA
AGGAATGTTTTTCTATTCAGGTTTTGCGTTCTTCTACCATTTAGCAAGACAAAATAAAATGGTAGGAACTTCTACAATGA
TTAGTTATATCAATCGTGATGAATTAGAGCATGGCCGATTTATAACCGAACTCTTCCGAGCAACTCTAGAAGAAAATCCA
TCTCATAACAATGCTGAATTTATTGATTGGATTTATGATCGTTTCCAACAATCAGTTGAGTTAGAGATTGAATGGTCTCA
TTATGTGTTAAATAAATTAGAAGGTATAGATATGGATGATATGGATGGTTATATCAAATATCGTGCTAACAAAATGTTGA
GAATGATGGGATTAGAGGAACTATATCCACAGCATGTGGAAAATCCAATGAAGTGGGTTCGTGCATATGTGGACAACTTT
GATGGTACGAAAACAGATTTCTTCGAACAGAAATCTCGTCAATATACCAAAACAAGTGATTTGAACGGTTTTGATGATTT
ATAA

Upstream 100 bases:

>100_bases
CATTTTTATGGAAGCTCTCATCCAGTATTAAAAATTGAGCAGTCTCCGAGAGGTTATCAACAACGAGCTGTATATGATTG
GCTAGAAGGAGTGTTACATC

Downstream 100 bases:

>100_bases
AAAAGCGGATTACTAACTTCCGCTTTTTTTATTTTGCTTGTGGATATCCTATTTTATAACAGATAATGGACTGTGATTAA
TCACAGTAGTCGCAGATGTT

Product: ribonucleotide-diphosphate reductase subunit beta

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MQKVMLEKAKTLEPRNPNKSTKLFGGESSGILNWNDIAYPHWYKMYKRLVGNYWQADEVNMSSDVKQFSTLSKEEQDAYL
KIIGLLSTLDAPQTRTALLISLYATDPSVQSIMAVIAQQEAVHNESYSYVLSSVVSWNEQNEAFQLGRTDELLLKRNEQL
TEQYNAFVDNPSMENMLKTLVYTSLLEGMFFYSGFAFFYHLARQNKMVGTSTMISYINRDELEHGRFITELFRATLEENP
SHNNAEFIDWIYDRFQQSVELEIEWSHYVLNKLEGIDMDDMDGYIKYRANKMLRMMGLEELYPQHVENPMKWVRAYVDNF
DGTKTDFFEQKSRQYTKTSDLNGFDDL

Sequences:

>Translated_347_residues
MQKVMLEKAKTLEPRNPNKSTKLFGGESSGILNWNDIAYPHWYKMYKRLVGNYWQADEVNMSSDVKQFSTLSKEEQDAYL
KIIGLLSTLDAPQTRTALLISLYATDPSVQSIMAVIAQQEAVHNESYSYVLSSVVSWNEQNEAFQLGRTDELLLKRNEQL
TEQYNAFVDNPSMENMLKTLVYTSLLEGMFFYSGFAFFYHLARQNKMVGTSTMISYINRDELEHGRFITELFRATLEENP
SHNNAEFIDWIYDRFQQSVELEIEWSHYVLNKLEGIDMDDMDGYIKYRANKMLRMMGLEELYPQHVENPMKWVRAYVDNF
DGTKTDFFEQKSRQYTKTSDLNGFDDL
>Mature_347_residues
MQKVMLEKAKTLEPRNPNKSTKLFGGESSGILNWNDIAYPHWYKMYKRLVGNYWQADEVNMSSDVKQFSTLSKEEQDAYL
KIIGLLSTLDAPQTRTALLISLYATDPSVQSIMAVIAQQEAVHNESYSYVLSSVVSWNEQNEAFQLGRTDELLLKRNEQL
TEQYNAFVDNPSMENMLKTLVYTSLLEGMFFYSGFAFFYHLARQNKMVGTSTMISYINRDELEHGRFITELFRATLEENP
SHNNAEFIDWIYDRFQQSVELEIEWSHYVLNKLEGIDMDDMDGYIKYRANKMLRMMGLEELYPQHVENPMKWVRAYVDNF
DGTKTDFFEQKSRQYTKTSDLNGFDDL

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Homo sapiens, GI289177074, Length=305, Percent_Identity=24.9180327868852, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI42544136, Length=305, Percent_Identity=24.9180327868852, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789031, Length=306, Percent_Identity=24.8366013071895, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1788567, Length=337, Percent_Identity=22.5519287833828, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17551968, Length=304, Percent_Identity=22.6973684210526, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18079279, Length=305, Percent_Identity=22.9508196721311, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 40625; Mature: 40625

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKVMLEKAKTLEPRNPNKSTKLFGGESSGILNWNDIAYPHWYKMYKRLVGNYWQADEVN
CCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
MSSDVKQFSTLSKEEQDAYLKIIGLLSTLDAPQTRTALLISLYATDPSVQSIMAVIAQQE
CHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHEEEEEEECCCHHHHHHHHHHHHHH
AVHNESYSYVLSSVVSWNEQNEAFQLGRTDELLLKRNEQLTEQYNAFVDNPSMENMLKTL
HHHCHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
VYTSLLEGMFFYSGFAFFYHLARQNKMVGTSTMISYINRDELEHGRFITELFRATLEENP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SHNNAEFIDWIYDRFQQSVELEIEWSHYVLNKLEGIDMDDMDGYIKYRANKMLRMMGLEE
CCCCHHHHHHHHHHHHCCEEEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHH
LYPQHVENPMKWVRAYVDNFDGTKTDFFEQKSRQYTKTSDLNGFDDL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQKVMLEKAKTLEPRNPNKSTKLFGGESSGILNWNDIAYPHWYKMYKRLVGNYWQADEVN
CCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
MSSDVKQFSTLSKEEQDAYLKIIGLLSTLDAPQTRTALLISLYATDPSVQSIMAVIAQQE
CHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHEEEEEEECCCHHHHHHHHHHHHHH
AVHNESYSYVLSSVVSWNEQNEAFQLGRTDELLLKRNEQLTEQYNAFVDNPSMENMLKTL
HHHCHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
VYTSLLEGMFFYSGFAFFYHLARQNKMVGTSTMISYINRDELEHGRFITELFRATLEENP
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SHNNAEFIDWIYDRFQQSVELEIEWSHYVLNKLEGIDMDDMDGYIKYRANKMLRMMGLEE
CCCCHHHHHHHHHHHHCCEEEEEEHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCHHH
LYPQHVENPMKWVRAYVDNFDGTKTDFFEQKSRQYTKTSDLNGFDDL
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]