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The map label for this gene is argS

Identifier: 23100470

GI number: 23100470

Start: 3125929

End: 3127599

Strand: Reverse

Name: argS

Synonym: OB3015

Alternate gene names: 23100470

Gene position: 3127599-3125929 (Counterclockwise)

Preceding gene: 23100471

Following gene: 23100469

Centisome position: 86.15

GC content: 37.7

Gene sequence:

>1671_bases
ATGAACGTATTAGAACAAACGGAACAAAAATTAAAAGAACAAATTCATCATGCTGTTATTCACGCGGAACTAGCAACAGA
GGATCAGGTACCTGATATCATTCTGGAAAAACCGAAAGATAAAGCTCATGGAGACTTCGCTACTAATATCGCGATGCAAC
TAGCACGAGTTGCCAAAAAAGCACCTCGACAAATTGCAGACGACATCGCCAGCAAGCTAAATAAATCAGAAGCGTCTGTT
GAAAAAGTTGAAATTGCAGGGCCTGGATTTATTAATTTTTTCATGAAGCAAGACTTCTTAGGTGAAGTGATTGATACCGT
ATTATCTGCAGGTGATAATTACGGAAAATCAACAGGTGGAAATGGAGAAAAAGTCCAAGTAGAATTTGTATCTGTAAATC
CAACCGGGGACTTGCATTTAGGGCATGCTCGAAATGCTGCTTTTGGGGATGTGCTTTGTAATGTATTTGCAGCTGCTGGT
TATGAAGTTGAGAGAGAATATTATATTAATGATGCAGGAAACCAAATAAACAATCTTGGATTATCTGTAGAAGCACGTTA
CTTGCAAGAAATTGGTCAAGATGTGGATATGCCAGAGGATGGTTATCAAGGTCAAGCCATTATCGAAATTGCTAAAGAGC
TAGTGAAGAAAGATGGAGAAAAATGGGCGGATAAAGATCATGAAGAACGCTTAGATTTCTTTAAAGAGTATGGTTTAAAA
GCATCATTAAGAAATATCGAATCGGATTTAAAAGACTTTCGTGTAGAATTTGATCATTGGTTCTCCGAGCGTTCTCTATT
TAAAGATGGACAAATTGATGACACATTAGCCGTGCTTGATGATGGTGGCTATACATTTGAAAAAGACGGAGCACTTTGGT
TTAAAACGACGGAATTCGGTGATGATAAAGACCGCGTATTAATTAAAGGTGATGGGAATTATACTTATTTAACCCCAGAT
ATCGCATACCACAAAAACAAGCTAGATCGCGGATTTGATCGTATTATAAATGTATGGGGATCAGACCATCATGGCTATAT
TCCACGTATGCGTGCTGCTCTTCAAGCATTGGGATATCCAGTGGAAAAATTTGATGTGAAAATTATTCAAATGGTAAATC
TATTTGAAGCAGGCGAAAAAGTGAAGATGAGTAAGCGTACAGGAAAGGCTGTTTCACTTCGAGAATTGATGGATGAGGTA
GGAATTGATGCAGTTCGATATTATTTCGTTGCACGTTCCAACGATTCACAATTAGATTTCGATATGGATTTAGCAAAGTC
GCAATCTAACGACAACCCAGTGTACTATGCACAATACGCACATGCACGTATTTGCACCATGCTTTCTCAGGCAAAAAGTA
AAGGATTCAATACCGAAGCTGAATTTGATGCATCTTTATTAACAGCTGAGAAAGAATTAGATCTATTGAAGAAAATTGGT
GAGCTTCCACAAATGATAGTTGATGCTGCTGATAAGCATACACCACATAAAGTGACTCAATATATCTTTGAACTTGCTAC
ATTATTACACAGCTTCTATAATGCTGAAAAAGTATTAGATGCGGATAATGAAGCTAGAACACATGCACGAATAGCTCTAA
TGAAAGCTGTTCGTCAAACACTCGCAAATGCTATGACAATTATCGGAATCTCTGCACCAGAGAAAATGTAA

Upstream 100 bases:

>100_bases
CGATAAAGGAAATCTACAAATGGATTATAAAATGAAACTCAATGGACAATTAGAAAGAGAACATAGATTGGTACTGACAT
ATTCTTAGGAGGACATCGAC

Downstream 100 bases:

>100_bases
ATAATCTTAGAAAGCCTATCCCTTTTCGATTTCAAAAGGGGGTAGGCTTTTTTGGGAGTCCAGAAAAAATGATAGGTAAG
CCTTATTACGTTTCGTTAAA

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MNVLEQTEQKLKEQIHHAVIHAELATEDQVPDIILEKPKDKAHGDFATNIAMQLARVAKKAPRQIADDIASKLNKSEASV
EKVEIAGPGFINFFMKQDFLGEVIDTVLSAGDNYGKSTGGNGEKVQVEFVSVNPTGDLHLGHARNAAFGDVLCNVFAAAG
YEVEREYYINDAGNQINNLGLSVEARYLQEIGQDVDMPEDGYQGQAIIEIAKELVKKDGEKWADKDHEERLDFFKEYGLK
ASLRNIESDLKDFRVEFDHWFSERSLFKDGQIDDTLAVLDDGGYTFEKDGALWFKTTEFGDDKDRVLIKGDGNYTYLTPD
IAYHKNKLDRGFDRIINVWGSDHHGYIPRMRAALQALGYPVEKFDVKIIQMVNLFEAGEKVKMSKRTGKAVSLRELMDEV
GIDAVRYYFVARSNDSQLDFDMDLAKSQSNDNPVYYAQYAHARICTMLSQAKSKGFNTEAEFDASLLTAEKELDLLKKIG
ELPQMIVDAADKHTPHKVTQYIFELATLLHSFYNAEKVLDADNEARTHARIALMKAVRQTLANAMTIIGISAPEKM

Sequences:

>Translated_556_residues
MNVLEQTEQKLKEQIHHAVIHAELATEDQVPDIILEKPKDKAHGDFATNIAMQLARVAKKAPRQIADDIASKLNKSEASV
EKVEIAGPGFINFFMKQDFLGEVIDTVLSAGDNYGKSTGGNGEKVQVEFVSVNPTGDLHLGHARNAAFGDVLCNVFAAAG
YEVEREYYINDAGNQINNLGLSVEARYLQEIGQDVDMPEDGYQGQAIIEIAKELVKKDGEKWADKDHEERLDFFKEYGLK
ASLRNIESDLKDFRVEFDHWFSERSLFKDGQIDDTLAVLDDGGYTFEKDGALWFKTTEFGDDKDRVLIKGDGNYTYLTPD
IAYHKNKLDRGFDRIINVWGSDHHGYIPRMRAALQALGYPVEKFDVKIIQMVNLFEAGEKVKMSKRTGKAVSLRELMDEV
GIDAVRYYFVARSNDSQLDFDMDLAKSQSNDNPVYYAQYAHARICTMLSQAKSKGFNTEAEFDASLLTAEKELDLLKKIG
ELPQMIVDAADKHTPHKVTQYIFELATLLHSFYNAEKVLDADNEARTHARIALMKAVRQTLANAMTIIGISAPEKM
>Mature_556_residues
MNVLEQTEQKLKEQIHHAVIHAELATEDQVPDIILEKPKDKAHGDFATNIAMQLARVAKKAPRQIADDIASKLNKSEASV
EKVEIAGPGFINFFMKQDFLGEVIDTVLSAGDNYGKSTGGNGEKVQVEFVSVNPTGDLHLGHARNAAFGDVLCNVFAAAG
YEVEREYYINDAGNQINNLGLSVEARYLQEIGQDVDMPEDGYQGQAIIEIAKELVKKDGEKWADKDHEERLDFFKEYGLK
ASLRNIESDLKDFRVEFDHWFSERSLFKDGQIDDTLAVLDDGGYTFEKDGALWFKTTEFGDDKDRVLIKGDGNYTYLTPD
IAYHKNKLDRGFDRIINVWGSDHHGYIPRMRAALQALGYPVEKFDVKIIQMVNLFEAGEKVKMSKRTGKAVSLRELMDEV
GIDAVRYYFVARSNDSQLDFDMDLAKSQSNDNPVYYAQYAHARICTMLSQAKSKGFNTEAEFDASLLTAEKELDLLKKIG
ELPQMIVDAADKHTPHKVTQYIFELATLLHSFYNAEKVLDADNEARTHARIALMKAVRQTLANAMTIIGISAPEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=604, Percent_Identity=25.8278145695364, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI197100773, Length=562, Percent_Identity=22.7758007117438, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1788184, Length=598, Percent_Identity=25.5852842809365, Blast_Score=146, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI71985061, Length=593, Percent_Identity=25.4637436762226, Blast_Score=125, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71985068, Length=554, Percent_Identity=25.812274368231, Blast_Score=114, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320548, Length=560, Percent_Identity=26.25, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6321883, Length=573, Percent_Identity=24.956369982548, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI18859963, Length=578, Percent_Identity=23.8754325259516, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28571570, Length=490, Percent_Identity=22.8571428571429, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_OCEIH (Q8EM45)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693937.1
- ProteinModelPortal:   Q8EM45
- GeneID:   1016713
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB3015
- NMPDR:   fig|221109.1.peg.3017
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- ProtClustDB:   PRK01611
- BioCyc:   OIHE221109:OB3015-MONOMER
- BRENDA:   6.1.1.19
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 62504; Mature: 62504

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00178 AA_TRNA_LIGASE_I; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLEQTEQKLKEQIHHAVIHAELATEDQVPDIILEKPKDKAHGDFATNIAMQLARVAKK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHH
APRQIADDIASKLNKSEASVEKVEIAGPGFINFFMKQDFLGEVIDTVLSAGDNYGKSTGG
HHHHHHHHHHHHHCCCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NGEKVQVEFVSVNPTGDLHLGHARNAAFGDVLCNVFAAAGYEVEREYYINDAGNQINNLG
CCCEEEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHCCCEECCEEEECCCCCHHHHCC
LSVEARYLQEIGQDVDMPEDGYQGQAIIEIAKELVKKDGEKWADKDHEERLDFFKEYGLK
CCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCH
ASLRNIESDLKDFRVEFDHWFSERSLFKDGQIDDTLAVLDDGGYTFEKDGALWFKTTEFG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEECCCEEEEEECCCC
DDKDRVLIKGDGNYTYLTPDIAYHKNKLDRGFDRIINVWGSDHHGYIPRMRAALQALGYP
CCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
VEKFDVKIIQMVNLFEAGEKVKMSKRTGKAVSLRELMDEVGIDAVRYYFVARSNDSQLDF
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHCCHHEEEEEEECCCCCCCCC
DMDLAKSQSNDNPVYYAQYAHARICTMLSQAKSKGFNTEAEFDASLLTAEKELDLLKKIG
CHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
ELPQMIVDAADKHTPHKVTQYIFELATLLHSFYNAEKVLDADNEARTHARIALMKAVRQT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHH
LANAMTIIGISAPEKM
HHHHEEEEEECCCCCC
>Mature Secondary Structure
MNVLEQTEQKLKEQIHHAVIHAELATEDQVPDIILEKPKDKAHGDFATNIAMQLARVAKK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHH
APRQIADDIASKLNKSEASVEKVEIAGPGFINFFMKQDFLGEVIDTVLSAGDNYGKSTGG
HHHHHHHHHHHHHCCCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NGEKVQVEFVSVNPTGDLHLGHARNAAFGDVLCNVFAAAGYEVEREYYINDAGNQINNLG
CCCEEEEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHCCCEECCEEEECCCCCHHHHCC
LSVEARYLQEIGQDVDMPEDGYQGQAIIEIAKELVKKDGEKWADKDHEERLDFFKEYGLK
CCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCH
ASLRNIESDLKDFRVEFDHWFSERSLFKDGQIDDTLAVLDDGGYTFEKDGALWFKTTEFG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEECCCEEEEEECCCC
DDKDRVLIKGDGNYTYLTPDIAYHKNKLDRGFDRIINVWGSDHHGYIPRMRAALQALGYP
CCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
VEKFDVKIIQMVNLFEAGEKVKMSKRTGKAVSLRELMDEVGIDAVRYYFVARSNDSQLDF
HHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHCCHHEEEEEEECCCCCCCCC
DMDLAKSQSNDNPVYYAQYAHARICTMLSQAKSKGFNTEAEFDASLLTAEKELDLLKKIG
CHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
ELPQMIVDAADKHTPHKVTQYIFELATLLHSFYNAEKVLDADNEARTHARIALMKAVRQT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHH
LANAMTIIGISAPEKM
HHHHEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376