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The map label for this gene is rpoE

Identifier: 23100463

GI number: 23100463

Start: 3117330

End: 3117851

Strand: Reverse

Name: rpoE

Synonym: OB3008

Alternate gene names: 23100463

Gene position: 3117851-3117330 (Counterclockwise)

Preceding gene: 23100464

Following gene: 23100462

Centisome position: 85.88

GC content: 35.44

Gene sequence:

>522_bases
GTGAGTTTGCAACAATTAACCCATGATGAGATTGACCATTTATCCATGATTGAGCTAGGAGTAAAAATTCTTAAAGAAGA
AAACAAAGCAATGAATTATAAGGTAATATTCAATAAGATTGCTGAGTTGAAAGATTTTACCGATGAGCAAAAACAAAATA
TGATGGCACAATTCTATACGGATATGAATGTGGATGGTCGTTTTCTTACATTAGGTTCTGGTATGTGGGGATTGAAACGA
TGGTATCCGGTAGAACAAGCAGAGGAAGAAATTACGGAAGAACCGAAGAAAAAAACGAAGAAGAAAAAGAAGAAAGCAGA
AGTCATTGATGACGTGGATGATGACCTGGATGTAACAGATGATGAAATCGATGATATTGTTAGCGATCTAGGTGATGATT
TAGATGATGACGATTTTGAAGATGATTTAGATGAAGATTTAGAGGATCTTGAAGATGAAGTCGATGAGCTTGAAGCGGAT
GAAGATGTAGAAGATGAAAACGATGATGACAATACTCGTTAA

Upstream 100 bases:

>100_bases
TTGATTCAGGTAGTAATAGTTCAACTATGAACTGGATATACAAAAGGTACATAGGCAGTAAGATTTGCCTTGATTATATT
TGCTAAGGGAGTGCATGAAC

Downstream 100 bases:

>100_bases
GAAGTCTTGACATTTTACAAGACAATGAGTACAATCTTTATTGGGCTCTTTGAATCGAAATACAAAGCGTTTTCCCAGTT
AAATGGGGGAACGCTTTTCT

Product: DNA-directed RNA polymerase delta chain

Products: diphosphate; RNAn+1

Alternate protein names: RNAP delta factor

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MSLQQLTHDEIDHLSMIELGVKILKEENKAMNYKVIFNKIAELKDFTDEQKQNMMAQFYTDMNVDGRFLTLGSGMWGLKR
WYPVEQAEEEITEEPKKKTKKKKKKAEVIDDVDDDLDVTDDEIDDIVSDLGDDLDDDDFEDDLDEDLEDLEDEVDELEAD
EDVEDENDDDNTR

Sequences:

>Translated_173_residues
MSLQQLTHDEIDHLSMIELGVKILKEENKAMNYKVIFNKIAELKDFTDEQKQNMMAQFYTDMNVDGRFLTLGSGMWGLKR
WYPVEQAEEEITEEPKKKTKKKKKKAEVIDDVDDDLDVTDDEIDDIVSDLGDDLDDDDFEDDLDEDLEDLEDEVDELEAD
EDVEDENDDDNTR
>Mature_172_residues
SLQQLTHDEIDHLSMIELGVKILKEENKAMNYKVIFNKIAELKDFTDEQKQNMMAQFYTDMNVDGRFLTLGSGMWGLKRW
YPVEQAEEEITEEPKKKTKKKKKKAEVIDDVDDDLDVTDDEIDDIVSDLGDDLDDDDFEDDLDEDLEDLEDEVDELEADE
DVEDENDDDNTR

Specific function: Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis

COG id: COG3343

COG function: function code K; DNA-directed RNA polymerase, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rpoE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOE_OCEIH (Q8EM52)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693930.1
- GeneID:   1017912
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB3008
- NMPDR:   fig|221109.1.peg.3010
- OMA:   TDMNTDG
- BioCyc:   OIHE221109:OB3008-MONOMER
- HAMAP:   MF_00357
- InterPro:   IPR007759
- PANTHER:   PTHR23405:SF1

Pfam domain/function: PF05066 RNA_pol_delta

EC number: 2.7.7.6

Molecular weight: Translated: 20206; Mature: 20075

Theoretical pI: Translated: 3.75; Mature: 3.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQQLTHDEIDHLSMIELGVKILKEENKAMNYKVIFNKIAELKDFTDEQKQNMMAQFYT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMNVDGRFLTLGSGMWGLKRWYPVEQAEEEITEEPKKKTKKKKKKAEVIDDVDDDLDVTD
CCCCCCCEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
DEIDDIVSDLGDDLDDDDFEDDLDEDLEDLEDEVDELEADEDVEDENDDDNTR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLQQLTHDEIDHLSMIELGVKILKEENKAMNYKVIFNKIAELKDFTDEQKQNMMAQFYT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DMNVDGRFLTLGSGMWGLKRWYPVEQAEEEITEEPKKKTKKKKKKAEVIDDVDDDLDVTD
CCCCCCCEEEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
DEIDDIVSDLGDDLDDDDFEDDLDEDLEDLEDEVDELEADEDVEDENDDDNTR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nucleoside triphosphate; RNAn

Specific reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376