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The map label for this gene is tal

Identifier: 23100459

GI number: 23100459

Start: 3113217

End: 3113858

Strand: Reverse

Name: tal

Synonym: OB3004

Alternate gene names: 23100459

Gene position: 3113858-3113217 (Counterclockwise)

Preceding gene: 23100460

Following gene: 23100458

Centisome position: 85.77

GC content: 37.23

Gene sequence:

>642_bases
ATGAAATTTTTTATTGATACAGCTAATATTGATGATATTCGAGCTGCGAATTCATTAGGTATACTAGCAGGTGTAACAAC
AAACCCGAGCTTAGTGGCTAAAGAAGGAGTTTCTTTCCACGATCGTTTACGTGAAATTACAAAAGAAGTATCTGGCTCTG
TGAGTGCAGAAGTTATTTCTGAAGATGCAGAAGGCATGATAGAAGAAGGAAAAGAGTTAGCAGCTATTGCTCCTAACATT
ACAGTAAAAGTTCCAATGACATTAGAAGGCTTAAAAGCCGTTAAAGTTTTTAGTGAGTTAAATATCAAAACAAATGTAAC
ACTTATTTTTAATGCGAATCAAGCGCTACTTGCAGCACGTGCTGGTGCGACATATGTATCTCCGTTTTTAGGCCGTTTAG
ATGATATTGGACAAGATGGCATGACTCTAATTTCTGCCATTGCTGAAATTTTTGATAGACACAGTGTGTCCACAGAAATT
ATTGCAGCATCTATACGCCATCCACTTCATGTAACCGATGCTGCACTTAATGGTGCACATATTGCGACTATTCCTTACAA
AGTATTGGAACAACTTGTGAAGCACCCACTTACAGATCAAGGTATCCAAAAATTCCTAGATGATTGGAATAGCCAAAAAT
AA

Upstream 100 bases:

>100_bases
GTTCTTCTAACCAAGCATAATCACATAAATGAAATCAAAGAGCTGTACCAATGGTGCAGCTTTTCCAACAGTTTTCACAA
AAAAGCGAGGAGGAATTGTA

Downstream 100 bases:

>100_bases
TTACATGAATTTGGTAAATTAGGAAACACTACAAATGTAATGATGTTAAACAAGCCTACTAACAACATACAGTGTGTTCA
ACAAAGAACACCTCTTTAGG

Product: putative translaldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MKFFIDTANIDDIRAANSLGILAGVTTNPSLVAKEGVSFHDRLREITKEVSGSVSAEVISEDAEGMIEEGKELAAIAPNI
TVKVPMTLEGLKAVKVFSELNIKTNVTLIFNANQALLAARAGATYVSPFLGRLDDIGQDGMTLISAIAEIFDRHSVSTEI
IAASIRHPLHVTDAALNGAHIATIPYKVLEQLVKHPLTDQGIQKFLDDWNSQK

Sequences:

>Translated_213_residues
MKFFIDTANIDDIRAANSLGILAGVTTNPSLVAKEGVSFHDRLREITKEVSGSVSAEVISEDAEGMIEEGKELAAIAPNI
TVKVPMTLEGLKAVKVFSELNIKTNVTLIFNANQALLAARAGATYVSPFLGRLDDIGQDGMTLISAIAEIFDRHSVSTEI
IAASIRHPLHVTDAALNGAHIATIPYKVLEQLVKHPLTDQGIQKFLDDWNSQK
>Mature_213_residues
MKFFIDTANIDDIRAANSLGILAGVTTNPSLVAKEGVSFHDRLREITKEVSGSVSAEVISEDAEGMIEEGKELAAIAPNI
TVKVPMTLEGLKAVKVFSELNIKTNVTLIFNANQALLAARAGATYVSPFLGRLDDIGQDGMTLISAIAEIFDRHSVSTEI
IAASIRHPLHVTDAALNGAHIATIPYKVLEQLVKHPLTDQGIQKFLDDWNSQK

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 3B subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=174, Percent_Identity=31.0344827586207, Blast_Score=67, Evalue=9e-12,
Organism=Escherichia coli, GI87081788, Length=212, Percent_Identity=33.4905660377358, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790382, Length=213, Percent_Identity=36.6197183098592, Blast_Score=136, Evalue=9e-34,
Organism=Escherichia coli, GI1788807, Length=171, Percent_Identity=30.4093567251462, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786189, Length=173, Percent_Identity=30.0578034682081, Blast_Score=61, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25153750, Length=223, Percent_Identity=29.1479820627803, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321480, Length=174, Percent_Identity=31.6091954022989, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAL_OCEIH (Q8CX76)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693926.1
- ProteinModelPortal:   Q8CX76
- SMR:   Q8CX76
- GeneID:   1017932
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB3004
- NMPDR:   fig|221109.1.peg.3006
- HOGENOM:   HBG533000
- OMA:   IHKNIVI
- ProtClustDB:   PRK01362
- BioCyc:   OIHE221109:OB3004-MONOMER
- BRENDA:   2.2.1.2
- GO:   GO:0005737
- HAMAP:   MF_00494
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004731
- InterPro:   IPR022999
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- TIGRFAMs:   TIGR00875

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 22960; Mature: 22960

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFIDTANIDDIRAANSLGILAGVTTNPSLVAKEGVSFHDRLREITKEVSGSVSAEVIS
CEEEEECCCCCHHHHCCCCEEEEECCCCCCHHHHCCCCHHHHHHHHHHHHCCCHHHHHHH
EDAEGMIEEGKELAAIAPNITVKVPMTLEGLKAVKVFSELNIKTNVTLIFNANQALLAAR
HHHHHHHHCCCCEEEECCCCEEEECCCHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHH
AGATYVSPFLGRLDDIGQDGMTLISAIAEIFDRHSVSTEIIAASIRHPLHVTDAALNGAH
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEHHHHCCCCE
IATIPYKVLEQLVKHPLTDQGIQKFLDDWNSQK
EEECCHHHHHHHHHCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKFFIDTANIDDIRAANSLGILAGVTTNPSLVAKEGVSFHDRLREITKEVSGSVSAEVIS
CEEEEECCCCCHHHHCCCCEEEEECCCCCCHHHHCCCCHHHHHHHHHHHHCCCHHHHHHH
EDAEGMIEEGKELAAIAPNITVKVPMTLEGLKAVKVFSELNIKTNVTLIFNANQALLAAR
HHHHHHHHCCCCEEEECCCCEEEECCCHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHH
AGATYVSPFLGRLDDIGQDGMTLISAIAEIFDRHSVSTEIIAASIRHPLHVTDAALNGAH
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEHHHHCCCCE
IATIPYKVLEQLVKHPLTDQGIQKFLDDWNSQK
EEECCHHHHHHHHHCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376