Click here to switch to the map view.

The map label for this gene is ywlE [H]

Identifier: 23100443

GI number: 23100443

Start: 3099233

End: 3099835

Strand: Reverse

Name: ywlE [H]

Synonym: OB2988

Alternate gene names: 23100443

Gene position: 3099835-3099233 (Counterclockwise)

Preceding gene: 23100446

Following gene: 23100442

Centisome position: 85.38

GC content: 36.15

Gene sequence:

>603_bases
ATGAATGTTTTATTTATATGCACAGGAAATACTTGCCGAAGTCCAATGGCAGAGGGGTTGTTAAAAAGTAAGATGCCAGC
CTTCAATGTGAAATCTGCAGGAACGGCAGCAATGGATCGAAGCCCTGCGTCAAACCATACCATGCAGGCATTATCTGAAA
AAGGCATTGACATGCACCATTATTCTCAATCTGTAAATGAAGAGTTATTAGAGTGGGCAGATATCGTCCTTACGATGACT
ACTTCACATAAACAATCGTTAATTATTCAATTCCCAGAGCAACAAAGCAAGTATTTTACCCTTAAAGAATATGTTTCAGA
AGCCGATAAAGAAATATGGGGACAGATACAAAAGGCCTATGCTGATTTAGAAGAAAAGCGTGCTTTATTTATTCAGAAGC
ATCAACATATGATGAACAACTTTCAGCTGCATCAATCAGTTTCAAAGGAATTTCAGACAGAAATTAATGAAATACAGCGT
TTGGAATCCAAACTAATCAATTATGATATTTCTGATCCATTTGGAGGTGGATTAGATCAATATCGTAATACGATGAAAGA
AATTGAAGACTGCATAGACCTTTTTGTTCAAAAACATACGTAA

Upstream 100 bases:

>100_bases
TTTTTTGGTAGGTTATAATGGCTATATAAGAAAATTAAGGTGAATGTGTACATACATCATATAATATATTATTGTTTTAA
AAATAAGTGGAGGGTTAATT

Downstream 100 bases:

>100_bases
TGCAGGAGGAAATTATGAAGAAAAAGTATCGGTTCAGTCTACGCTTGAAGCTTGTTGTTTTAATAACTGTATTAGCAATG
ATTACTTATGGATTTAGCGC

Product: protein-tyrosine-phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MNVLFICTGNTCRSPMAEGLLKSKMPAFNVKSAGTAAMDRSPASNHTMQALSEKGIDMHHYSQSVNEELLEWADIVLTMT
TSHKQSLIIQFPEQQSKYFTLKEYVSEADKEIWGQIQKAYADLEEKRALFIQKHQHMMNNFQLHQSVSKEFQTEINEIQR
LESKLINYDISDPFGGGLDQYRNTMKEIEDCIDLFVQKHT

Sequences:

>Translated_200_residues
MNVLFICTGNTCRSPMAEGLLKSKMPAFNVKSAGTAAMDRSPASNHTMQALSEKGIDMHHYSQSVNEELLEWADIVLTMT
TSHKQSLIIQFPEQQSKYFTLKEYVSEADKEIWGQIQKAYADLEEKRALFIQKHQHMMNNFQLHQSVSKEFQTEINEIQR
LESKLINYDISDPFGGGLDQYRNTMKEIEDCIDLFVQKHT
>Mature_200_residues
MNVLFICTGNTCRSPMAEGLLKSKMPAFNVKSAGTAAMDRSPASNHTMQALSEKGIDMHHYSQSVNEELLEWADIVLTMT
TSHKQSLIIQFPEQQSKYFTLKEYVSEADKEIWGQIQKAYADLEEKRALFIQKHQHMMNNFQLHQSVSKEFQTEINEIQR
LESKLINYDISDPFGGGLDQYRNTMKEIEDCIDLFVQKHT

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI87081812, Length=112, Percent_Identity=29.4642857142857, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788375, Length=109, Percent_Identity=30.2752293577982, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 23042; Mature: 23042

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLFICTGNTCRSPMAEGLLKSKMPAFNVKSAGTAAMDRSPASNHTMQALSEKGIDMHH
CCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHCCCCHHH
YSQSVNEELLEWADIVLTMTTSHKQSLIIQFPEQQSKYFTLKEYVSEADKEIWGQIQKAY
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ADLEEKRALFIQKHQHMMNNFQLHQSVSKEFQTEINEIQRLESKLINYDISDPFGGGLDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
YRNTMKEIEDCIDLFVQKHT
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVLFICTGNTCRSPMAEGLLKSKMPAFNVKSAGTAAMDRSPASNHTMQALSEKGIDMHH
CCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHCCCCHHH
YSQSVNEELLEWADIVLTMTTSHKQSLIIQFPEQQSKYFTLKEYVSEADKEIWGQIQKAY
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ADLEEKRALFIQKHQHMMNNFQLHQSVSKEFQTEINEIQRLESKLINYDISDPFGGGLDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
YRNTMKEIEDCIDLFVQKHT
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7798145; 9384377 [H]