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The map label for this gene is atpH

Identifier: 23100433

GI number: 23100433

Start: 3089292

End: 3089837

Strand: Reverse

Name: atpH

Synonym: OB2978

Alternate gene names: 23100433

Gene position: 3089837-3089292 (Counterclockwise)

Preceding gene: 23100434

Following gene: 23100432

Centisome position: 85.11

GC content: 36.45

Gene sequence:

>546_bases
ATGAGTAACTCCGTAGTAGCAAAACGTTATGCAGATGCGCTTTTTCAGCTTGGTAGAGAGAAGAATTCATTAGACCAATT
AGTAGCAGATTTTCTTGAGGTTCGACAAATATTTACAAATGATCAAAAATTAAATGTTTTCCTGAAGCATCCAAAGATTG
ACAATGAGAAAAAGAAACAGTTTTTAGCTGATGTGTTTAAAGGTGCGGATCCAGTTGTAATAAATACGCTGAAGTTACTT
GTAGATCGTCATCGCACATCAACCATTCCATCTATTGTTGATCACCTAGTCGCTTTGGTAAACGATACAAAAGGAATTGC
AGACGCAACCGTCTATTCCATTCGAGAATTAAATACCGATGAAAAGGAACAACTTCAAACATCCTTTGCTAAACGTTTAG
GGAAAAGAAGTGTTCAAATTACGAATGTTGTGGATCCTAAGATTCTCGGCGGTATGAAAATAAGAGTCGGAAATACGATA
TACGATGGAACGGTAAGTAATAAGTTAAACCGAATTTCACGTAGTATCGTGTCTGCTAACAAATGA

Upstream 100 bases:

>100_bases
TATCTGTATTAATTGCAAGTAAGGTAATTGAAAAAGAACTTAGCGAACAAGATCAAGAAAAACTAATTAATGAATACATT
CAAGAAGTTGGGGAAGATCG

Downstream 100 bases:

>100_bases
TGATAGGGGTGAAATGGTATGAGCATTAATGCTGAAGAAATTAGCACACTGATTAAACAGCAAATTGAAAACTTTGATTC
TGACATCGAAGTAAGTGATG

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MSNSVVAKRYADALFQLGREKNSLDQLVADFLEVRQIFTNDQKLNVFLKHPKIDNEKKKQFLADVFKGADPVVINTLKLL
VDRHRTSTIPSIVDHLVALVNDTKGIADATVYSIRELNTDEKEQLQTSFAKRLGKRSVQITNVVDPKILGGMKIRVGNTI
YDGTVSNKLNRISRSIVSANK

Sequences:

>Translated_181_residues
MSNSVVAKRYADALFQLGREKNSLDQLVADFLEVRQIFTNDQKLNVFLKHPKIDNEKKKQFLADVFKGADPVVINTLKLL
VDRHRTSTIPSIVDHLVALVNDTKGIADATVYSIRELNTDEKEQLQTSFAKRLGKRSVQITNVVDPKILGGMKIRVGNTI
YDGTVSNKLNRISRSIVSANK
>Mature_180_residues
SNSVVAKRYADALFQLGREKNSLDQLVADFLEVRQIFTNDQKLNVFLKHPKIDNEKKKQFLADVFKGADPVVINTLKLLV
DRHRTSTIPSIVDHLVALVNDTKGIADATVYSIRELNTDEKEQLQTSFAKRLGKRSVQITNVVDPKILGGMKIRVGNTIY
DGTVSNKLNRISRSIVSANK

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family

Homologues:

Organism=Homo sapiens, GI4502303, Length=171, Percent_Identity=26.9005847953216, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71984710, Length=178, Percent_Identity=26.4044943820225, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71984717, Length=178, Percent_Identity=26.4044943820225, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24647054, Length=168, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPD_OCEIH (Q8EM80)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693900.1
- ProteinModelPortal:   Q8EM80
- SMR:   Q8EM80
- GeneID:   1016737
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2978
- NMPDR:   fig|221109.1.peg.2981
- HOGENOM:   HBG668108
- OMA:   SIGDKYV
- ProtClustDB:   PRK05758
- BioCyc:   OIHE221109:OB2978-MONOMER
- HAMAP:   MF_01416
- InterPro:   IPR000711
- InterPro:   IPR020781
- Gene3D:   G3DSA:1.10.520.20
- PANTHER:   PTHR11910
- PRINTS:   PR00125
- TIGRFAMs:   TIGR01145

Pfam domain/function: PF00213 OSCP; SSF47928 ATPsynt_OSCP

EC number: 3.6.3.14

Molecular weight: Translated: 20307; Mature: 20175

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSVVAKRYADALFQLGREKNSLDQLVADFLEVRQIFTNDQKLNVFLKHPKIDNEKKKQ
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHH
FLADVFKGADPVVINTLKLLVDRHRTSTIPSIVDHLVALVNDTKGIADATVYSIRELNTD
HHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
EKEQLQTSFAKRLGKRSVQITNVVDPKILGGMKIRVGNTIYDGTVSNKLNRISRSIVSAN
HHHHHHHHHHHHHCCCCEEEECCCCHHHHCCEEEEECCEEECCHHHHHHHHHHHHHHHCC
K
C
>Mature Secondary Structure 
SNSVVAKRYADALFQLGREKNSLDQLVADFLEVRQIFTNDQKLNVFLKHPKIDNEKKKQ
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHH
FLADVFKGADPVVINTLKLLVDRHRTSTIPSIVDHLVALVNDTKGIADATVYSIRELNTD
HHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
EKEQLQTSFAKRLGKRSVQITNVVDPKILGGMKIRVGNTIYDGTVSNKLNRISRSIVSAN
HHHHHHHHHHHHHCCCCEEEECCCCHHHHCCEEEEECCEEECCHHHHHHHHHHHHHHHCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12235376