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The map label for this gene is desR [H]

Identifier: 23100305

GI number: 23100305

Start: 2934310

End: 2934909

Strand: Reverse

Name: desR [H]

Synonym: OB2850

Alternate gene names: 23100305

Gene position: 2934909-2934310 (Counterclockwise)

Preceding gene: 23100306

Following gene: 23100304

Centisome position: 80.84

GC content: 42.5

Gene sequence:

>600_bases
TTGATTCGAATTGTAATTGCTGAAGATCAACAATTGTTGCTTGGAGCTTTGGGCACGCTTCTTAGTATGGAAGAGGACAT
GGAAGTGGTTGGGCAAGCGAAGAATGGGGAAGAGGTATTGAATTTAGTGGAACAAAAGAAACCGGATGTCTGTATCATGG
ACATAGAGATGCCTGTGAAGACTGGGTTAGATGCGGCCGAGGAATTACGAGACGATGACTGTAAGGTAATTGTCTTAACT
ACTTTCGCCCGTACGGGATATTTTGAACGAGCACGTAAAGCGAATGTCAACGGATATTTATTAAAGGACAGTCCTAGTGA
AGATTTAGCCAATTCCATTCGCGCTATTATGGCTGGTCGCAAGGTGTATGCACCAGAATTAATTGATATGGCCTATGAGG
AAGGCAATCCACTGACAACCCGTGAGGAACAAGTGCTCAAGCTCATTGCCGACGGAAAGACAACGAAGGAGATTGCAGGT
CAACTTTATTTAACAAATGGTACGGTTCGTAATTATGTATCCACAATCATGGATAAATTGAACGTCAGCAACCGTATAGA
GGCGATTTCGAGAATTAAAGAAAAGGGTTGGTTTAAATAG

Upstream 100 bases:

>100_bases
TTAATGGAAACCTATCGTTTGATGAGACGAATAAGAGCAAAACCATACTTAGCATCCAAGTGCCACGAGTAATTCAACAA
ACGGAACAGGAGGGGTCGAA

Downstream 100 bases:

>100_bases
TTTCATCCTAACTATTTTTTATTTAAATTTTCAAAAAATAGTCATCTTGTCTGATTGTTTCTACTACTTGTCCTTGATAA
TCTATTAGTGAACAAAATAA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MIRIVIAEDQQLLLGALGTLLSMEEDMEVVGQAKNGEEVLNLVEQKKPDVCIMDIEMPVKTGLDAAEELRDDDCKVIVLT
TFARTGYFERARKANVNGYLLKDSPSEDLANSIRAIMAGRKVYAPELIDMAYEEGNPLTTREEQVLKLIADGKTTKEIAG
QLYLTNGTVRNYVSTIMDKLNVSNRIEAISRIKEKGWFK

Sequences:

>Translated_199_residues
MIRIVIAEDQQLLLGALGTLLSMEEDMEVVGQAKNGEEVLNLVEQKKPDVCIMDIEMPVKTGLDAAEELRDDDCKVIVLT
TFARTGYFERARKANVNGYLLKDSPSEDLANSIRAIMAGRKVYAPELIDMAYEEGNPLTTREEQVLKLIADGKTTKEIAG
QLYLTNGTVRNYVSTIMDKLNVSNRIEAISRIKEKGWFK
>Mature_199_residues
MIRIVIAEDQQLLLGALGTLLSMEEDMEVVGQAKNGEEVLNLVEQKKPDVCIMDIEMPVKTGLDAAEELRDDDCKVIVLT
TFARTGYFERARKANVNGYLLKDSPSEDLANSIRAIMAGRKVYAPELIDMAYEEGNPLTTREEQVLKLIADGKTTKEIAG
QLYLTNGTVRNYVSTIMDKLNVSNRIEAISRIKEKGWFK

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=198, Percent_Identity=31.3131313131313, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788521, Length=207, Percent_Identity=31.4009661835749, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788222, Length=199, Percent_Identity=27.6381909547739, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787473, Length=208, Percent_Identity=31.25, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1788712, Length=187, Percent_Identity=28.3422459893048, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1786747, Length=202, Percent_Identity=23.7623762376238, Blast_Score=70, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22258; Mature: 22258

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRIVIAEDQQLLLGALGTLLSMEEDMEVVGQAKNGEEVLNLVEQKKPDVCIMDIEMPVK
CEEEEEECCHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCHH
TGLDAAEELRDDDCKVIVLTTFARTGYFERARKANVNGYLLKDSPSEDLANSIRAIMAGR
HCCCHHHHHCCCCCEEEEEECCHHHCHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCC
KVYAPELIDMAYEEGNPLTTREEQVLKLIADGKTTKEIAGQLYLTNGTVRNYVSTIMDKL
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHCCEEEEECCHHHHHHHHHHHHH
NVSNRIEAISRIKEKGWFK
CHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIRIVIAEDQQLLLGALGTLLSMEEDMEVVGQAKNGEEVLNLVEQKKPDVCIMDIEMPVK
CEEEEEECCHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCHH
TGLDAAEELRDDDCKVIVLTTFARTGYFERARKANVNGYLLKDSPSEDLANSIRAIMAGR
HCCCHHHHHCCCCCEEEEEECCHHHCHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCC
KVYAPELIDMAYEEGNPLTTREEQVLKLIADGKTTKEIAGQLYLTNGTVRNYVSTIMDKL
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHCCEEEEECCHHHHHHHHHHHHH
NVSNRIEAISRIKEKGWFK
CHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]