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The map label for this gene is solA [H]

Identifier: 23100257

GI number: 23100257

Start: 2883291

End: 2884418

Strand: Direct

Name: solA [H]

Synonym: OB2802

Alternate gene names: 23100257

Gene position: 2883291-2884418 (Clockwise)

Preceding gene: 23100255

Following gene: 23100260

Centisome position: 79.42

GC content: 38.3

Gene sequence:

>1128_bases
TTGATTTACGATATTGCAGTTATTGGAGCAGGATCGATGGGCTTATCAGCGGGATATTATCTTTCAAAAGCTGGAAAAAC
TGTAGCACTGATTGATTCTAATGATCCACCTCATTCAGAAGGTTCCCATCATGGGGAAACTCGAATTATTCGACATGCAT
ATGGCGAAGGAGCAGCATACGTCCCATTGGCATTAAGATCGCAAGAATTGTGGAATGATCTCAATCAAACGTTTAATCAA
GATATATTTCATCAGACTGGTGTATTAAATATCGGAGGGGATAATTCTGTATTTTTACAGAATGTGATTCAATCTGTTCG
TCAATATAGATTACAAGCTGAGATTCTATCAGCAAAGCAAATCAATAGTAGATGGCATGGGTTTCGGTTACCTGATCATC
TAATGGGGGTTTATGAAACGAATTCTGGCGTGTTAATGAGTGAAAAAGTTCTCCAGTCTTATCGAGACTTAGCTACAGCA
CTCGGCGCCTCCTTTTATACCAATGCATATATTCACCATTTGGATGTAACAAATCAACACATAACAATACAATTATCAAG
TGATACGATAAAAGCTAAGCAACTTATCATCACTGCGGGAAAAGGAACAAATCAAATATTATCTTTACTTGGCTATGAGC
TACCATTATTCCCAGTTCGAAAGACGTTCTCGTGGTTCAAGACAGATGAATCTATCTATCATTCTGATGCCTTTCCTGCC
TGGTCTTTTGATAATGGAAACGAAAAATACTACGGCTTCCCTAGTATTGATAATGCTGGTATAAAAATTGGCAGACATGA
CGGTGGCCATCCTGTGAAGGCAGATGAAGCCTTGAAAACTTTTGGAACATACCGTGAAGATAAAGAAGATGTTAGTCAAT
TTGTTCATCGATACATGTCTCCTAATATACAGCACAGCCAAGGGAAGGTTTGCACCTATACAAATACTCCAGACGGTGAC
TTCATTATCGATCGACTGCCAAACTATCAACATGTACTTGTCGCTTGTGGTTTCTCTGGTCACGGTTTTAAATTTAGCAG
TGCCGTTGGAGAATTATTAAGTCAATTGGCAATTCGAGGAGAAACTAGTTTAGATATATCCCCTTTTTCTTTAAATAGAT
TCGTATAA

Upstream 100 bases:

>100_bases
CTTTCCCATTTAGGAAATCTGCTCAGTGAAATTATTAATTGAACCCTCAACCACTATCCATTAAAATACTCATATATAAA
GGAAAGGAGATGGGGTAATC

Downstream 100 bases:

>100_bases
ATGTAAAAAACAAGGAACGCTGGCAACAACGATCCTTGTTTTTTATTATGGGCTACACGCCCCGCTTGTTTCCCCACAAA
TAGGTGTGCAATTGTGGTAA

Product: N-methyltryptophan oxidase

Products: NA

Alternate protein names: MSOX [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MIYDIAVIGAGSMGLSAGYYLSKAGKTVALIDSNDPPHSEGSHHGETRIIRHAYGEGAAYVPLALRSQELWNDLNQTFNQ
DIFHQTGVLNIGGDNSVFLQNVIQSVRQYRLQAEILSAKQINSRWHGFRLPDHLMGVYETNSGVLMSEKVLQSYRDLATA
LGASFYTNAYIHHLDVTNQHITIQLSSDTIKAKQLIITAGKGTNQILSLLGYELPLFPVRKTFSWFKTDESIYHSDAFPA
WSFDNGNEKYYGFPSIDNAGIKIGRHDGGHPVKADEALKTFGTYREDKEDVSQFVHRYMSPNIQHSQGKVCTYTNTPDGD
FIIDRLPNYQHVLVACGFSGHGFKFSSAVGELLSQLAIRGETSLDISPFSLNRFV

Sequences:

>Translated_375_residues
MIYDIAVIGAGSMGLSAGYYLSKAGKTVALIDSNDPPHSEGSHHGETRIIRHAYGEGAAYVPLALRSQELWNDLNQTFNQ
DIFHQTGVLNIGGDNSVFLQNVIQSVRQYRLQAEILSAKQINSRWHGFRLPDHLMGVYETNSGVLMSEKVLQSYRDLATA
LGASFYTNAYIHHLDVTNQHITIQLSSDTIKAKQLIITAGKGTNQILSLLGYELPLFPVRKTFSWFKTDESIYHSDAFPA
WSFDNGNEKYYGFPSIDNAGIKIGRHDGGHPVKADEALKTFGTYREDKEDVSQFVHRYMSPNIQHSQGKVCTYTNTPDGD
FIIDRLPNYQHVLVACGFSGHGFKFSSAVGELLSQLAIRGETSLDISPFSLNRFV
>Mature_375_residues
MIYDIAVIGAGSMGLSAGYYLSKAGKTVALIDSNDPPHSEGSHHGETRIIRHAYGEGAAYVPLALRSQELWNDLNQTFNQ
DIFHQTGVLNIGGDNSVFLQNVIQSVRQYRLQAEILSAKQINSRWHGFRLPDHLMGVYETNSGVLMSEKVLQSYRDLATA
LGASFYTNAYIHHLDVTNQHITIQLSSDTIKAKQLIITAGKGTNQILSLLGYELPLFPVRKTFSWFKTDESIYHSDAFPA
WSFDNGNEKYYGFPSIDNAGIKIGRHDGGHPVKADEALKTFGTYREDKEDVSQFVHRYMSPNIQHSQGKVCTYTNTPDGD
FIIDRLPNYQHVLVACGFSGHGFKFSSAVGELLSQLAIRGETSLDISPFSLNRFV

Specific function: Catalyzes the oxidative demethylation of sarcosine [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MSOX/MTOX family. MSOX subfamily [H]

Homologues:

Organism=Homo sapiens, GI60499001, Length=382, Percent_Identity=32.4607329842932, Blast_Score=199, Evalue=3e-51,
Organism=Escherichia coli, GI1787298, Length=377, Percent_Identity=40.5835543766578, Blast_Score=297, Evalue=6e-82,
Organism=Caenorhabditis elegans, GI25147318, Length=390, Percent_Identity=24.3589743589744, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI115535191, Length=389, Percent_Identity=25.706940874036, Blast_Score=118, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006281 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 41745; Mature: 41745

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYDIAVIGAGSMGLSAGYYLSKAGKTVALIDSNDPPHSEGSHHGETRIIRHAYGEGAAY
CEEEEEEEECCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCEE
VPLALRSQELWNDLNQTFNQDIFHQTGVLNIGGDNSVFLQNVIQSVRQYRLQAEILSAKQ
EEEEHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
INSRWHGFRLPDHLMGVYETNSGVLMSEKVLQSYRDLATALGASFYTNAYIHHLDVTNQH
HHCCCCCCCCHHHHEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCE
ITIQLSSDTIKAKQLIITAGKGTNQILSLLGYELPLFPVRKTFSWFKTDESIYHSDAFPA
EEEEECCCCEEEEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHEECCCCCC
WSFDNGNEKYYGFPSIDNAGIKIGRHDGGHPVKADEALKTFGTYREDKEDVSQFVHRYMS
CCCCCCCCEEECCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHC
PNIQHSQGKVCTYTNTPDGDFIIDRLPNYQHVLVACGFSGHGFKFSSAVGELLSQLAIRG
CCCCCCCCCEEEECCCCCCCCCEECCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHCC
ETSLDISPFSLNRFV
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MIYDIAVIGAGSMGLSAGYYLSKAGKTVALIDSNDPPHSEGSHHGETRIIRHAYGEGAAY
CEEEEEEEECCCCCCCCCEEEECCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCEE
VPLALRSQELWNDLNQTFNQDIFHQTGVLNIGGDNSVFLQNVIQSVRQYRLQAEILSAKQ
EEEEHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
INSRWHGFRLPDHLMGVYETNSGVLMSEKVLQSYRDLATALGASFYTNAYIHHLDVTNQH
HHCCCCCCCCHHHHEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCE
ITIQLSSDTIKAKQLIITAGKGTNQILSLLGYELPLFPVRKTFSWFKTDESIYHSDAFPA
EEEEECCCCEEEEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHEECCCCCC
WSFDNGNEKYYGFPSIDNAGIKIGRHDGGHPVKADEALKTFGTYREDKEDVSQFVHRYMS
CCCCCCCCEEECCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHC
PNIQHSQGKVCTYTNTPDGDFIIDRLPNYQHVLVACGFSGHGFKFSSAVGELLSQLAIRG
CCCCCCCCCEEEECCCCCCCCCEECCCCCEEEEEEECCCCCCEEHHHHHHHHHHHHHHCC
ETSLDISPFSLNRFV
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1368683 [H]