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The map label for this gene is stc [H]

Identifier: 23100194

GI number: 23100194

Start: 2809709

End: 2811493

Strand: Reverse

Name: stc [H]

Synonym: OB2739

Alternate gene names: 23100194

Gene position: 2811493-2809709 (Counterclockwise)

Preceding gene: 23100195

Following gene: 23100193

Centisome position: 77.44

GC content: 35.24

Gene sequence:

>1785_bases
ATGAAACAGAGTCACCATATCACAGAAGAAGAGTCAACAGTTTCGGATTGGATGATAACGAAATCGGTACATGTTCTTTC
CACGCATTCTATGAAAGAAGTTGCCAAACTATATAATGAAATAAATGAAGACGTAATTATTGTAATCGAACAAGGCAAGC
CAATTGGAATCATTACCGGAAAATCTATTGTACAAGCTCTTTTAGATCATGGAGAAACTAGGCCAGTAACTGAATATATT
TCTCGAAATGATTTTCAGCTTATTCATTTTGACCAATCTATTATCGATGCATGTAAACTTCCGACAACCAATTGTTTAGT
AGTGAACGATGAACATAAATTTGTAGGGTTACTAACATACCATGAGATTCAGCGCGGGTTAGTACACTATATACATAAAT
TAGATCAATCATTTCATTCTGCAGAAATCGTAGAGGTAATTCTTGAAAGTGCCTATGAAGGTGTTGCAATGGTAGATAGA
AATGGGATAATAGTTGAATTTAATGATGCGTATAGTCGTTTTACTGGAGTCGATAAAAAGGAAGCCATTGGGCATCCGGT
ACAAGAAATAATTGAAAATACAAATCTTCATCAAACTGTGAAGACAGGAATAGCTGAACGTGGGGTTATTCAATATATAC
AAGGACAGCCAATGGTCGTACATCGAATACCTGTATGGAGAAATGAAGAATTAGTAGGTGCGATTGGGATGCTCATTTTT
GAAGGAGTGACGGAACTCTACCAGATCTATGATCGTTATCAAGAGAAGAAACAAAAAATGATAACCGAAAAACATTCAAG
AAAAGAGGATAGTAATCCCGGACAGCCTGACAATTATTTGGAACAAATTATTGGGCAAAGCGAAGAGTTAACTAAATTAA
AACGAATGACAAGAAAAGTCGCCCAAACAGAGGCAACAGTATTAATAACTGGGGACAGTGGGACAGGTAAAGAATTATTT
GCAAAAAGTATTCACCAATTGAGCGATTATAAATCTGGTCCATTTGTTTGTGTGAATTGTGGGGCAATACCTGAACAATT
GTTTGAATCTGAGTTATTTGGTTATGAAGATGGGTCATTTACTGGTGCAAAGCGAGGAGGAAAAAAAGGTAAATTTAAAC
TTGCCGACAATGGAACGTTATTTCTTGATGAAATTGGAGAAATGCCTCTTGCCATGCAGACGAAATTACTTAGAGTAATC
CAAGAGAAAGAGTATGAAAAAGTAGGTGGATTGACAAAGCAGCCGTTAAAAGCCAGAGTTGTTGCTGCTACAAATCGAAA
TTTGAAAGTTATGGTAGAGGAGGGGACTTTTAGAGAAGACTTATATTATCGTATTAATGTAATCGAATTATATATTCCTC
CGCTTCGAAACAGAGAAAGAGATATTCCATTACTTATATCTTCTTATCTACTAACAATTTGTAAAAAGTATAACATGAAG
AAAAAAGAGATAACACCAGAAGCGATGGCGGTACTAATGAAATATAAATGGTATGGAAATATTCGAGAATTAATTAATAC
AATAGAAAAGCTCGTTATATTAACGGAGAATGATATGATAGATTATCACCATCTACCAAACTATATGAAAAGAGAAGAGT
TTACGATAGATAATCGTTTATCCCCCATACACCAAGTCAAGCAACAAGAACATATTCGAGAAAGCGAGTTAATAAGACTT
ACGTTAGAACAAACTGGTGGGAACAAATCCAAAGCGGCTCAGAAATTAGGGATACACCGAACCACGCTTTATCAAAAATT
AAAAAAGTTTGATATGGAGATGTAG

Upstream 100 bases:

>100_bases
CTGGACAACTTTTTATATGCAGTAAATTATTTTGAATTTTTAAACTCATAGTAATTTCAATGTATAATAGACTTAAAATT
GAAATGAGAGGGGTATTAGC

Downstream 100 bases:

>100_bases
TGTAGTTAAATGCCTACACAACGCTACAATAGTGTAGTTTTTTCCCTACACTCTTTGTTTTTAATTATCGGCATAGGAGT
CATCATTAGTTGGCATGAAT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MKQSHHITEEESTVSDWMITKSVHVLSTHSMKEVAKLYNEINEDVIIVIEQGKPIGIITGKSIVQALLDHGETRPVTEYI
SRNDFQLIHFDQSIIDACKLPTTNCLVVNDEHKFVGLLTYHEIQRGLVHYIHKLDQSFHSAEIVEVILESAYEGVAMVDR
NGIIVEFNDAYSRFTGVDKKEAIGHPVQEIIENTNLHQTVKTGIAERGVIQYIQGQPMVVHRIPVWRNEELVGAIGMLIF
EGVTELYQIYDRYQEKKQKMITEKHSRKEDSNPGQPDNYLEQIIGQSEELTKLKRMTRKVAQTEATVLITGDSGTGKELF
AKSIHQLSDYKSGPFVCVNCGAIPEQLFESELFGYEDGSFTGAKRGGKKGKFKLADNGTLFLDEIGEMPLAMQTKLLRVI
QEKEYEKVGGLTKQPLKARVVAATNRNLKVMVEEGTFREDLYYRINVIELYIPPLRNRERDIPLLISSYLLTICKKYNMK
KKEITPEAMAVLMKYKWYGNIRELINTIEKLVILTENDMIDYHHLPNYMKREEFTIDNRLSPIHQVKQQEHIRESELIRL
TLEQTGGNKSKAAQKLGIHRTTLYQKLKKFDMEM

Sequences:

>Translated_594_residues
MKQSHHITEEESTVSDWMITKSVHVLSTHSMKEVAKLYNEINEDVIIVIEQGKPIGIITGKSIVQALLDHGETRPVTEYI
SRNDFQLIHFDQSIIDACKLPTTNCLVVNDEHKFVGLLTYHEIQRGLVHYIHKLDQSFHSAEIVEVILESAYEGVAMVDR
NGIIVEFNDAYSRFTGVDKKEAIGHPVQEIIENTNLHQTVKTGIAERGVIQYIQGQPMVVHRIPVWRNEELVGAIGMLIF
EGVTELYQIYDRYQEKKQKMITEKHSRKEDSNPGQPDNYLEQIIGQSEELTKLKRMTRKVAQTEATVLITGDSGTGKELF
AKSIHQLSDYKSGPFVCVNCGAIPEQLFESELFGYEDGSFTGAKRGGKKGKFKLADNGTLFLDEIGEMPLAMQTKLLRVI
QEKEYEKVGGLTKQPLKARVVAATNRNLKVMVEEGTFREDLYYRINVIELYIPPLRNRERDIPLLISSYLLTICKKYNMK
KKEITPEAMAVLMKYKWYGNIRELINTIEKLVILTENDMIDYHHLPNYMKREEFTIDNRLSPIHQVKQQEHIRESELIRL
TLEQTGGNKSKAAQKLGIHRTTLYQKLKKFDMEM
>Mature_594_residues
MKQSHHITEEESTVSDWMITKSVHVLSTHSMKEVAKLYNEINEDVIIVIEQGKPIGIITGKSIVQALLDHGETRPVTEYI
SRNDFQLIHFDQSIIDACKLPTTNCLVVNDEHKFVGLLTYHEIQRGLVHYIHKLDQSFHSAEIVEVILESAYEGVAMVDR
NGIIVEFNDAYSRFTGVDKKEAIGHPVQEIIENTNLHQTVKTGIAERGVIQYIQGQPMVVHRIPVWRNEELVGAIGMLIF
EGVTELYQIYDRYQEKKQKMITEKHSRKEDSNPGQPDNYLEQIIGQSEELTKLKRMTRKVAQTEATVLITGDSGTGKELF
AKSIHQLSDYKSGPFVCVNCGAIPEQLFESELFGYEDGSFTGAKRGGKKGKFKLADNGTLFLDEIGEMPLAMQTKLLRVI
QEKEYEKVGGLTKQPLKARVVAATNRNLKVMVEEGTFREDLYYRINVIELYIPPLRNRERDIPLLISSYLLTICKKYNMK
KKEITPEAMAVLMKYKWYGNIRELINTIEKLVILTENDMIDYHHLPNYMKREEFTIDNRLSPIHQVKQQEHIRESELIRL
TLEQTGGNKSKAAQKLGIHRTTLYQKLKKFDMEM

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=314, Percent_Identity=44.2675159235669, Blast_Score=272, Evalue=5e-74,
Organism=Escherichia coli, GI1790437, Length=342, Percent_Identity=41.812865497076, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI1789233, Length=340, Percent_Identity=38.8235294117647, Blast_Score=257, Evalue=2e-69,
Organism=Escherichia coli, GI87082117, Length=362, Percent_Identity=40.6077348066298, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1789087, Length=422, Percent_Identity=36.7298578199052, Blast_Score=254, Evalue=2e-68,
Organism=Escherichia coli, GI1788905, Length=325, Percent_Identity=39.6923076923077, Blast_Score=245, Evalue=5e-66,
Organism=Escherichia coli, GI1786524, Length=378, Percent_Identity=37.3015873015873, Blast_Score=241, Evalue=9e-65,
Organism=Escherichia coli, GI1790299, Length=375, Percent_Identity=36.2666666666667, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI87082152, Length=235, Percent_Identity=45.1063829787234, Blast_Score=205, Evalue=7e-54,
Organism=Escherichia coli, GI87081872, Length=331, Percent_Identity=37.4622356495468, Blast_Score=202, Evalue=6e-53,
Organism=Escherichia coli, GI1787583, Length=394, Percent_Identity=31.7258883248731, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI87081858, Length=309, Percent_Identity=32.3624595469256, Blast_Score=155, Evalue=9e-39,
Organism=Escherichia coli, GI1789828, Length=282, Percent_Identity=32.6241134751773, Blast_Score=129, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 68229; Mature: 68229

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQSHHITEEESTVSDWMITKSVHVLSTHSMKEVAKLYNEINEDVIIVIEQGKPIGIITG
CCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECC
KSIVQALLDHGETRPVTEYISRNDFQLIHFDQSIIDACKLPTTNCLVVNDEHKFVGLLTY
HHHHHHHHHCCCCCCHHHHHCCCCCEEEEECHHHHHHHCCCCCCEEEECCCCCEEEHHHH
HEIQRGLVHYIHKLDQSFHSAEIVEVILESAYEGVAMVDRNGIIVEFNDAYSRFTGVDKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCHHHHHCCCCHH
EAIGHPVQEIIENTNLHQTVKTGIAERGVIQYIQGQPMVVHRIPVWRNEELVGAIGMLIF
HHCCCHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
EGVTELYQIYDRYQEKKQKMITEKHSRKEDSNPGQPDNYLEQIIGQSEELTKLKRMTRKV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
AQTEATVLITGDSGTGKELFAKSIHQLSDYKSGPFVCVNCGAIPEQLFESELFGYEDGSF
HHCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCC
TGAKRGGKKGKFKLADNGTLFLDEIGEMPLAMQTKLLRVIQEKEYEKVGGLTKQPLKARV
CCCCCCCCCCCEEECCCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
VAATNRNLKVMVEEGTFREDLYYRINVIELYIPPLRNRERDIPLLISSYLLTICKKYNMK
EEECCCCEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
KKEITPEAMAVLMKYKWYGNIRELINTIEKLVILTENDMIDYHHLPNYMKREEFTIDNRL
HHCCCHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCCCHHHCCCHHHHCCCCCCCCC
SPIHQVKQQEHIRESELIRLTLEQTGGNKSKAAQKLGIHRTTLYQKLKKFDMEM
CHHHHHHHHHHCCHHHEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKQSHHITEEESTVSDWMITKSVHVLSTHSMKEVAKLYNEINEDVIIVIEQGKPIGIITG
CCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEECC
KSIVQALLDHGETRPVTEYISRNDFQLIHFDQSIIDACKLPTTNCLVVNDEHKFVGLLTY
HHHHHHHHHCCCCCCHHHHHCCCCCEEEEECHHHHHHHCCCCCCEEEECCCCCEEEHHHH
HEIQRGLVHYIHKLDQSFHSAEIVEVILESAYEGVAMVDRNGIIVEFNDAYSRFTGVDKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCHHHHHCCCCHH
EAIGHPVQEIIENTNLHQTVKTGIAERGVIQYIQGQPMVVHRIPVWRNEELVGAIGMLIF
HHCCCHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
EGVTELYQIYDRYQEKKQKMITEKHSRKEDSNPGQPDNYLEQIIGQSEELTKLKRMTRKV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHH
AQTEATVLITGDSGTGKELFAKSIHQLSDYKSGPFVCVNCGAIPEQLFESELFGYEDGSF
HHCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCC
TGAKRGGKKGKFKLADNGTLFLDEIGEMPLAMQTKLLRVIQEKEYEKVGGLTKQPLKARV
CCCCCCCCCCCEEECCCCEEEHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
VAATNRNLKVMVEEGTFREDLYYRINVIELYIPPLRNRERDIPLLISSYLLTICKKYNMK
EEECCCCEEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
KKEITPEAMAVLMKYKWYGNIRELINTIEKLVILTENDMIDYHHLPNYMKREEFTIDNRL
HHCCCHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCCCHHHCCCHHHHCCCCCCCCC
SPIHQVKQQEHIRESELIRLTLEQTGGNKSKAAQKLGIHRTTLYQKLKKFDMEM
CHHHHHHHHHHCCHHHEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA