BacMap

Definition	Oceanobacillus iheyensis HTE831, complete genome.
Accession	NC_004193
Length	3,630,528

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The map label for this gene is iolA2

Identifier: 23100191

GI number: 23100191

Start: 2805519

End: 2806979

Strand: Reverse

Name: iolA2

Synonym: OB2736

Alternate gene names: 23100191

Gene position: 2806979-2805519 (Counterclockwise)

Preceding gene: 23100192

Following gene: 23100188

Centisome position: 77.32

GC content: 39.84

Gene sequence:

>1461_bases
ATGACACAAACTACAGTAAAAAATGTAAAAAACTATATCGGTGGAGAATGGATTGAATCACGTACGGAAAAAACAGAGGA
TGTCTTTAATCCAGCTACAGGAGAAGTAATTGCACAAGTACCAATTTCAACAACTGAAGATGTGCATCATGCGATAGAGG
TAGCAAATGAAGCATTTAAGACTTGGAAGGAAGTTCCTGTTCCAAAACGGGCGCGAATTTTGTTTAAATATCAACAATTA
CTGGTGGAACATTGGGAAGAGTTAGCGAAGTTAATTACATTGGAAAATGGAAAAAATTACGCCGAAGCTTATGGAGAAGT
ACAACGTGGAATTGAGAATGTAGAATTTGCGACTGGTGCACCATCATTAATGATGGGAGAACAGCTCGCTTCTATTGCAA
CGGAATTAGAATCTGGTGTATATCGTTATCCGATAGGAGTGATTGGTGGAATTACACCGTTTAATTTTCCGATGATGGTA
CCGTGCTGGATGTTCCCGATGGCAATTGCTACTGGAAATACGTTTGTAATGAAACCTTCTGAACGTACACCATTATTAGC
AAATCGGTTGGCAGAACTATTAGAAGAAGCAGGTCTTCCAAACGGGGTATTCAATATTGTACATGGTGCTCATGATGTCG
TAAATGGGTTACTTGATCATAAAAAAGTTGCTGCTATTTCTTTTGTTGGTTCTCAGCCAGTAGCTGAATACGTATATAAA
CGAGGAACACAGAATTTGAAACGTGTACAGGCACTTGCAGGAGCAAAAAATCACTCGATCGTACTAAGTGATGCCAACCT
TGAAAATGCCACTACTCAAATATTAAATGCTGCATTCGGTTCTGCAGGCGAAAGATGTATGGCTGCATCAGTTGTAGCAG
TTGAAGAAGATGTTGCAGATGAATTTGTTACTTTATTAACGCAGAAAGCGAATGAAATAAAAATTGGAAATGGGTTAGAT
GAAGGGGTATTCCTTGGACCGGTAATCCGTGACCAACATAAGGAACGGACGTTGCAGTATATTGAATCAGGGGAAGAAGA
AGGTGCAAATCTTGTTCGCGATGGTCGTACAGACGAAGCAGCCAAACAAGAAGGTTATTTTGTCGGACCAACGATCTTTG
ATCATGTAACGTCAGAGATGAAAATTTGGCAAGATGAAATTTTTGCACCAGTGTTGTCGATTGCCCGTGTGAATAATTTA
GAGGAAGGTGTCGATTTAGCAAATGAATCTCGGTTTGCAAATGGGGCATGTATCTTTACAAGAGATGGGGGAAGCGTGCG
TAGATTTAGAGAGACTATCGATGCTGGCATGCTTGGTGTAAATATTGGTGTTCCTGCACCAATGGCATTCTTACCATTCT
CTGGTTGGAAAGATTCATTCTATGGGGATTTACATGCAAACGGAAAAGATGGATTACAATTTTATACACGTAAAAAAGTA
CTTACTACCAAATGGGTGTAG

Upstream 100 bases:

>100_bases
TAAACCAATTTTAATGGTAAGTGTTGTCTTACCTACGATTATTTTAGCGTTAGCAGTTATTTTGTACACCATATTTTAAA
TCTACTTAGGAGGACTTTAT

Downstream 100 bases:

>100_bases
GTATCAGCATACGCAAGTTGTCGAGGCATAATGCCAAAGACAGAATATGAGTTAGGTTTTATGTAATAATATCAGCCAAT
TTGAAAGAGAAATTTCTTTT

Product: methylmalonate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: MMSA dehydrogenase 2; MMSDH 2; MSDH 2; Malonate semialdehyde dehydrogenase [acetylating] 2; MSA dehydrogenase 2

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MTQTTVKNVKNYIGGEWIESRTEKTEDVFNPATGEVIAQVPISTTEDVHHAIEVANEAFKTWKEVPVPKRARILFKYQQL
LVEHWEELAKLITLENGKNYAEAYGEVQRGIENVEFATGAPSLMMGEQLASIATELESGVYRYPIGVIGGITPFNFPMMV
PCWMFPMAIATGNTFVMKPSERTPLLANRLAELLEEAGLPNGVFNIVHGAHDVVNGLLDHKKVAAISFVGSQPVAEYVYK
RGTQNLKRVQALAGAKNHSIVLSDANLENATTQILNAAFGSAGERCMAASVVAVEEDVADEFVTLLTQKANEIKIGNGLD
EGVFLGPVIRDQHKERTLQYIESGEEEGANLVRDGRTDEAAKQEGYFVGPTIFDHVTSEMKIWQDEIFAPVLSIARVNNL
EEGVDLANESRFANGACIFTRDGGSVRRFRETIDAGMLGVNIGVPAPMAFLPFSGWKDSFYGDLHANGKDGLQFYTRKKV
LTTKWV

Sequences:

>Translated_486_residues
MTQTTVKNVKNYIGGEWIESRTEKTEDVFNPATGEVIAQVPISTTEDVHHAIEVANEAFKTWKEVPVPKRARILFKYQQL
LVEHWEELAKLITLENGKNYAEAYGEVQRGIENVEFATGAPSLMMGEQLASIATELESGVYRYPIGVIGGITPFNFPMMV
PCWMFPMAIATGNTFVMKPSERTPLLANRLAELLEEAGLPNGVFNIVHGAHDVVNGLLDHKKVAAISFVGSQPVAEYVYK
RGTQNLKRVQALAGAKNHSIVLSDANLENATTQILNAAFGSAGERCMAASVVAVEEDVADEFVTLLTQKANEIKIGNGLD
EGVFLGPVIRDQHKERTLQYIESGEEEGANLVRDGRTDEAAKQEGYFVGPTIFDHVTSEMKIWQDEIFAPVLSIARVNNL
EEGVDLANESRFANGACIFTRDGGSVRRFRETIDAGMLGVNIGVPAPMAFLPFSGWKDSFYGDLHANGKDGLQFYTRKKV
LTTKWV
>Mature_485_residues
TQTTVKNVKNYIGGEWIESRTEKTEDVFNPATGEVIAQVPISTTEDVHHAIEVANEAFKTWKEVPVPKRARILFKYQQLL
VEHWEELAKLITLENGKNYAEAYGEVQRGIENVEFATGAPSLMMGEQLASIATELESGVYRYPIGVIGGITPFNFPMMVP
CWMFPMAIATGNTFVMKPSERTPLLANRLAELLEEAGLPNGVFNIVHGAHDVVNGLLDHKKVAAISFVGSQPVAEYVYKR
GTQNLKRVQALAGAKNHSIVLSDANLENATTQILNAAFGSAGERCMAASVVAVEEDVADEFVTLLTQKANEIKIGNGLDE
GVFLGPVIRDQHKERTLQYIESGEEEGANLVRDGRTDEAAKQEGYFVGPTIFDHVTSEMKIWQDEIFAPVLSIARVNNLE
EGVDLANESRFANGACIFTRDGGSVRRFRETIDAGMLGVNIGVPAPMAFLPFSGWKDSFYGDLHANGKDGLQFYTRKKVL
TTKWV

Specific function: Converts malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. IolA subfamily

Homologues:

Organism=Homo sapiens, GI11095441, Length=481, Percent_Identity=45.5301455301455, Blast_Score=454, Evalue=1e-128,
Organism=Homo sapiens, GI25777730, Length=479, Percent_Identity=35.9081419624217, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI21361176, Length=495, Percent_Identity=34.9494949494949, Blast_Score=264, Evalue=1e-70,
Organism=Homo sapiens, GI25777732, Length=479, Percent_Identity=35.0730688935282, Blast_Score=256, Evalue=3e-68,
Organism=Homo sapiens, GI115387104, Length=482, Percent_Identity=31.9502074688797, Blast_Score=255, Evalue=6e-68,
Organism=Homo sapiens, GI153266822, Length=485, Percent_Identity=34.020618556701, Blast_Score=245, Evalue=7e-65,
Organism=Homo sapiens, GI25777724, Length=485, Percent_Identity=32.5773195876289, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI12007648, Length=482, Percent_Identity=30.4979253112033, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI21614513, Length=485, Percent_Identity=32.1649484536082, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI238814322, Length=485, Percent_Identity=31.340206185567, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI25777726, Length=483, Percent_Identity=30.2277432712215, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI25777728, Length=419, Percent_Identity=32.9355608591885, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI188035924, Length=463, Percent_Identity=29.5896328293737, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI4507229, Length=457, Percent_Identity=29.1028446389497, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI310128103, Length=456, Percent_Identity=29.8245614035088, Blast_Score=195, Evalue=8e-50,
Organism=Homo sapiens, GI310128093, Length=446, Percent_Identity=29.8206278026906, Blast_Score=192, Evalue=8e-49,
Organism=Homo sapiens, GI25952152, Length=478, Percent_Identity=28.0334728033473, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI25777721, Length=470, Percent_Identity=28.0851063829787, Blast_Score=186, Evalue=6e-47,
Organism=Homo sapiens, GI310128091, Length=446, Percent_Identity=28.2511210762332, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI301500698, Length=285, Percent_Identity=29.4736842105263, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI310128087, Length=265, Percent_Identity=30.9433962264151, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI25777736, Length=382, Percent_Identity=28.0104712041885, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI25777734, Length=382, Percent_Identity=28.0104712041885, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI238859541, Length=382, Percent_Identity=28.0104712041885, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI206597441, Length=437, Percent_Identity=24.4851258581236, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI206597439, Length=437, Percent_Identity=24.4851258581236, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI22907049, Length=437, Percent_Identity=24.4851258581236, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI310128089, Length=308, Percent_Identity=28.5714285714286, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4557303, Length=439, Percent_Identity=23.6902050113895, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI73466520, Length=434, Percent_Identity=23.7327188940092, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI310128101, Length=214, Percent_Identity=30.8411214953271, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI310128099, Length=214, Percent_Identity=30.8411214953271, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI310128095, Length=304, Percent_Identity=27.6315789473684, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4502043, Length=420, Percent_Identity=25, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI238814371, Length=420, Percent_Identity=25, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI223972651, Length=484, Percent_Identity=25.4132231404959, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI310128097, Length=250, Percent_Identity=30, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI71773324, Length=335, Percent_Identity=25.3731343283582, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI73695881, Length=328, Percent_Identity=24.0853658536585, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI73695879, Length=328, Percent_Identity=24.0853658536585, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI223972653, Length=230, Percent_Identity=28.695652173913, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1789015, Length=471, Percent_Identity=32.6963906581741, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1787558, Length=482, Percent_Identity=33.402489626556, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI87081896, Length=485, Percent_Identity=31.9587628865979, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1786504, Length=479, Percent_Identity=32.9853862212944, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI87082295, Length=485, Percent_Identity=30.1030927835052, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1787684, Length=473, Percent_Identity=31.5010570824524, Blast_Score=211, Evalue=9e-56,
Organism=Escherichia coli, GI1787715, Length=473, Percent_Identity=31.0782241014799, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI87081926, Length=437, Percent_Identity=29.5194508009153, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1787250, Length=442, Percent_Identity=28.5067873303167, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI1788042, Length=451, Percent_Identity=25.7206208425721, Blast_Score=149, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI71986308, Length=478, Percent_Identity=43.5146443514644, Blast_Score=421, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17562198, Length=480, Percent_Identity=35.2083333333333, Blast_Score=254, Evalue=5e-68,
Organism=Caenorhabditis elegans, GI25144435, Length=483, Percent_Identity=33.5403726708075, Blast_Score=243, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI133930964, Length=485, Percent_Identity=32.3711340206186, Blast_Score=237, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI25143876, Length=472, Percent_Identity=30.5084745762712, Blast_Score=226, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI25143874, Length=472, Percent_Identity=30.5084745762712, Blast_Score=226, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI17534119, Length=476, Percent_Identity=31.0924369747899, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI32564736, Length=423, Percent_Identity=33.806146572104, Blast_Score=209, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI71995606, Length=476, Percent_Identity=29.4117647058824, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17551164, Length=481, Percent_Identity=30.7692307692308, Blast_Score=204, Evalue=9e-53,
Organism=Caenorhabditis elegans, GI71995613, Length=415, Percent_Identity=30.1204819277108, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI115534176, Length=479, Percent_Identity=29.4363256784969, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17534447, Length=441, Percent_Identity=26.0770975056689, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32564151, Length=397, Percent_Identity=27.455919395466, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17564084, Length=442, Percent_Identity=26.6968325791855, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI115532534, Length=356, Percent_Identity=25.8426966292135, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32566756, Length=438, Percent_Identity=25.3424657534247, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI25146391, Length=438, Percent_Identity=25.3424657534247, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI25146394, Length=438, Percent_Identity=25.3424657534247, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71990744, Length=318, Percent_Identity=26.1006289308176, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324950, Length=476, Percent_Identity=30.8823529411765, Blast_Score=249, Evalue=6e-67,
Organism=Saccharomyces cerevisiae, GI6320917, Length=470, Percent_Identity=32.5531914893617, Blast_Score=245, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6319478, Length=476, Percent_Identity=32.563025210084, Blast_Score=239, Evalue=7e-64,
Organism=Saccharomyces cerevisiae, GI6325196, Length=478, Percent_Identity=31.7991631799163, Blast_Score=231, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6323822, Length=480, Percent_Identity=31.6666666666667, Blast_Score=224, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6323821, Length=477, Percent_Identity=31.4465408805031, Blast_Score=214, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6321828, Length=464, Percent_Identity=27.1551724137931, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6321826, Length=462, Percent_Identity=27.4891774891775, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6323757, Length=352, Percent_Identity=25, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24638878, Length=477, Percent_Identity=44.0251572327044, Blast_Score=416, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24638876, Length=477, Percent_Identity=44.0251572327044, Blast_Score=416, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24650465, Length=483, Percent_Identity=35.4037267080745, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI20129399, Length=483, Percent_Identity=34.1614906832298, Blast_Score=261, Evalue=9e-70,
Organism=Drosophila melanogaster, GI24585660, Length=484, Percent_Identity=30.5785123966942, Blast_Score=247, Evalue=2e-65,
Organism=Drosophila melanogaster, GI281362580, Length=478, Percent_Identity=32.2175732217573, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI62472918, Length=478, Percent_Identity=32.2175732217573, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI62472926, Length=478, Percent_Identity=32.2175732217573, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI62472936, Length=478, Percent_Identity=32.2175732217573, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI21356737, Length=478, Percent_Identity=32.2175732217573, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI24666674, Length=462, Percent_Identity=28.3549783549784, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24668425, Length=396, Percent_Identity=27.7777777777778, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24668417, Length=396, Percent_Identity=27.7777777777778, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24668413, Length=396, Percent_Identity=27.7777777777778, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI45552499, Length=341, Percent_Identity=24.9266862170088, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281360303, Length=341, Percent_Identity=24.9266862170088, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571798, Length=365, Percent_Identity=25.7534246575342, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571796, Length=365, Percent_Identity=25.7534246575342, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571794, Length=365, Percent_Identity=25.7534246575342, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571802, Length=365, Percent_Identity=25.4794520547945, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571800, Length=365, Percent_Identity=25.4794520547945, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI28571806, Length=365, Percent_Identity=25.4794520547945, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281360301, Length=341, Percent_Identity=25.5131964809384, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281360299, Length=341, Percent_Identity=25.5131964809384, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281360297, Length=341, Percent_Identity=25.5131964809384, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI281360295, Length=341, Percent_Identity=25.5131964809384, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24586250, Length=341, Percent_Identity=25.5131964809384, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28574525, Length=403, Percent_Identity=21.3399503722084, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IOLA2_OCEIH (Q8EMV4)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693658.1
- HSSP:   P42412
- ProteinModelPortal:   Q8EMV4
- SMR:   Q8EMV4
- GeneID:   1016156
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2736
- NMPDR:   fig|221109.1.peg.2736
- HOGENOM:   HBG752218
- OMA:   AHKARIE
- BioCyc:   OIHE221109:OB2736-MONOMER
- HAMAP:   MF_01670
- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR010061
- Gene3D:   G3DSA:3.40.309.10
- Gene3D:   G3DSA:3.40.605.10
- PANTHER:   PTHR11699
- PANTHER:   PTHR11699:SF27
- TIGRFAMs:   TIGR01722

Pfam domain/function: PF00171 Aldedh; SSF53720 Aldehyde_DH/Histidinol_DH

EC number: =1.2.1.27; =1.2.1.18

Molecular weight: Translated: 53503; Mature: 53372

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS; PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: ACT_SITE 286-286 BINDING 386-386

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTTVKNVKNYIGGEWIESRTEKTEDVFNPATGEVIAQVPISTTEDVHHAIEVANEAFK
CCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHH
TWKEVPVPKRARILFKYQQLLVEHWEELAKLITLENGKNYAEAYGEVQRGIENVEFATGA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHCEECCCC
PSLMMGEQLASIATELESGVYRYPIGVIGGITPFNFPMMVPCWMFPMAIATGNTFVMKPS
CHHHHHHHHHHHHHHHHCCCEECCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCC
ERTPLLANRLAELLEEAGLPNGVFNIVHGAHDVVNGLLDHKKVAAISFVGSQPVAEYVYK
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHH
RGTQNLKRVQALAGAKNHSIVLSDANLENATTQILNAAFGSAGERCMAASVVAVEEDVAD
HCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EFVTLLTQKANEIKIGNGLDEGVFLGPVIRDQHKERTLQYIESGEEEGANLVRDGRTDEA
HHHHHHHHCCCCEECCCCCCCCCEECHHHHHHHHHHHHHHHHCCCHHCCHHHHCCCCCHH
AKQEGYFVGPTIFDHVTSEMKIWQDEIFAPVLSIARVNNLEEGVDLANESRFANGACIFT
HHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEE
RDGGSVRRFRETIDAGMLGVNIGVPAPMAFLPFSGWKDSFYGDLHANGKDGLQFYTRKKV
CCCCHHHHHHHHHHCCCEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LTTKWV
HHCCCC
>Mature Secondary Structure 
TQTTVKNVKNYIGGEWIESRTEKTEDVFNPATGEVIAQVPISTTEDVHHAIEVANEAFK
CCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHH
TWKEVPVPKRARILFKYQQLLVEHWEELAKLITLENGKNYAEAYGEVQRGIENVEFATGA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHCEECCCC
PSLMMGEQLASIATELESGVYRYPIGVIGGITPFNFPMMVPCWMFPMAIATGNTFVMKPS
CHHHHHHHHHHHHHHHHCCCEECCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCC
ERTPLLANRLAELLEEAGLPNGVFNIVHGAHDVVNGLLDHKKVAAISFVGSQPVAEYVYK
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHH
RGTQNLKRVQALAGAKNHSIVLSDANLENATTQILNAAFGSAGERCMAASVVAVEEDVAD
HCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
EFVTLLTQKANEIKIGNGLDEGVFLGPVIRDQHKERTLQYIESGEEEGANLVRDGRTDEA
HHHHHHHHCCCCEECCCCCCCCCEECHHHHHHHHHHHHHHHHCCCHHCCHHHHCCCCCHH
AKQEGYFVGPTIFDHVTSEMKIWQDEIFAPVLSIARVNNLEEGVDLANESRFANGACIFT
HHHCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEE
RDGGSVRRFRETIDAGMLGVNIGVPAPMAFLPFSGWKDSFYGDLHANGKDGLQFYTRKKV
CCCCHHHHHHHHHHCCCEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
LTTKWV
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376