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The map label for this gene is kdgK [H]

Identifier: 23100153

GI number: 23100153

Start: 2768813

End: 2769763

Strand: Reverse

Name: kdgK [H]

Synonym: OB2698

Alternate gene names: 23100153

Gene position: 2769763-2768813 (Counterclockwise)

Preceding gene: 23100154

Following gene: 23100152

Centisome position: 76.29

GC content: 38.38

Gene sequence:

>951_bases
ATGAAAGATATTATAACGTTAGGAGAGGCAATGGTAGTATTTAACCCAGCATCTACTGGACCGATGAAATTTGTAAATGG
ATTTCATAAGACAATTGGTGGAGCAGAGTTGAACTTGGCGATCGGATGCGCTCGATTAGGCCTGGATACTGGTTATATAA
CCAGGCTTGGTAATGATGAATTTGGGAAATCTATTCGTAATTTTGTAAGAGGGGAAGGCATTGATGCATCAGAAATAGAT
TTTATTGATCATTATCCGACATCAATTAATTTTAAAGAAATTATGGAAGACGGTAGTGTAAGAACATTTTATTATCGTGA
TAAATCGCCTACGTTATCCATGACACCGGATGTTCTAAATGAATCGTACTTTAAAAATGCAAAAATTCTTCACCTAACTG
GAATATTCCCTGCTATTGGAGAGGGAGCATTAAAAGTATGGAAGCAGGCAATACATTTAGCAAAGAAGCATGGAGTTAAA
ATATCCTTTGACCCAAATATTCGCTTAAAAATGTGGTCGAAGGAGCAAGCGCGTAAGGTATTGTTAGAAATACTGCCAGA
TGTTGATATTCTACTAGCTGGTGATGAGGAAATGGACATTATTATTGGAAAACGGGATCCAGTAGACATTATCGAAACGT
GTAAAGAATTAGGAATCCCGTATGTAGCGATTAAGCAAGGTGAAAACGGTTCAGTAGGGTATTCTCAAGGTGAAACGATG
AAGGCAGCTCCAGTTAAAGCTAGCAAAGTCGTGGATACGGTAGGTGCAGGAGATGGATTTAATGCTGGAATTCTTTATGG
CTATCTTCATGACTGGTCTTTAGAGCGGACACTTACATTTGGAAATACAATAGGATCGATGGTCGTTGGTATTACAGGTG
ATAATGAAGGACTACCGTATTATGAAGATGTCCAAGAACGACTAGGAGAAATAGAGAGAATAGAGCGGTAA

Upstream 100 bases:

>100_bases
GAAACTGGGATTTTTATAAATATGGTAGATAAAGCAATTGTTGCAGATAACGGTGAGTTATCCATATTGGAAAAATAAAA
GTTAATTGGGAGGGGTCTAT

Downstream 100 bases:

>100_bases
TTGAGGTGAGAATTTATGAAATTACAATTAGCATTGGATCGACTAACACGTGGAGAAAGTATTCGTATATTAGAAAGTGT
GAAACAATATGTTGATATTA

Product: 2-keto-3-deoxygluconate kinase

Products: NA

Alternate protein names: 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKDIITLGEAMVVFNPASTGPMKFVNGFHKTIGGAELNLAIGCARLGLDTGYITRLGNDEFGKSIRNFVRGEGIDASEID
FIDHYPTSINFKEIMEDGSVRTFYYRDKSPTLSMTPDVLNESYFKNAKILHLTGIFPAIGEGALKVWKQAIHLAKKHGVK
ISFDPNIRLKMWSKEQARKVLLEILPDVDILLAGDEEMDIIIGKRDPVDIIETCKELGIPYVAIKQGENGSVGYSQGETM
KAAPVKASKVVDTVGAGDGFNAGILYGYLHDWSLERTLTFGNTIGSMVVGITGDNEGLPYYEDVQERLGEIERIER

Sequences:

>Translated_316_residues
MKDIITLGEAMVVFNPASTGPMKFVNGFHKTIGGAELNLAIGCARLGLDTGYITRLGNDEFGKSIRNFVRGEGIDASEID
FIDHYPTSINFKEIMEDGSVRTFYYRDKSPTLSMTPDVLNESYFKNAKILHLTGIFPAIGEGALKVWKQAIHLAKKHGVK
ISFDPNIRLKMWSKEQARKVLLEILPDVDILLAGDEEMDIIIGKRDPVDIIETCKELGIPYVAIKQGENGSVGYSQGETM
KAAPVKASKVVDTVGAGDGFNAGILYGYLHDWSLERTLTFGNTIGSMVVGITGDNEGLPYYEDVQERLGEIERIER
>Mature_316_residues
MKDIITLGEAMVVFNPASTGPMKFVNGFHKTIGGAELNLAIGCARLGLDTGYITRLGNDEFGKSIRNFVRGEGIDASEID
FIDHYPTSINFKEIMEDGSVRTFYYRDKSPTLSMTPDVLNESYFKNAKILHLTGIFPAIGEGALKVWKQAIHLAKKHGVK
ISFDPNIRLKMWSKEQARKVLLEILPDVDILLAGDEEMDIIIGKRDPVDIIETCKELGIPYVAIKQGENGSVGYSQGETM
KAAPVKASKVVDTVGAGDGFNAGILYGYLHDWSLERTLTFGNTIGSMVVGITGDNEGLPYYEDVQERLGEIERIER

Specific function: Unknown

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87081971, Length=319, Percent_Identity=27.8996865203762, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082281, Length=318, Percent_Identity=27.3584905660377, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1790193, Length=291, Percent_Identity=22.3367697594502, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.45 [H]

Molecular weight: Translated: 34842; Mature: 34842

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDIITLGEAMVVFNPASTGPMKFVNGFHKTIGGAELNLAIGCARLGLDTGYITRLGNDE
CCCCEECCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEHHHHCCCCCCEEECCCHH
FGKSIRNFVRGEGIDASEIDFIDHYPTSINFKEIMEDGSVRTFYYRDKSPTLSMTPDVLN
HHHHHHHHHCCCCCCHHHCCHHHCCCCCCCHHHHHCCCCEEEEEEECCCCCEECCHHHHH
ESYFKNAKILHLTGIFPAIGEGALKVWKQAIHLAKKHGVKISFDPNIRLKMWSKEQARKV
HHHHCCCEEEEEECCCCHHCHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECCHHHHHHH
LLEILPDVDILLAGDEEMDIIIGKRDPVDIIETCKELGIPYVAIKQGENGSVGYSQGETM
HHHHCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCE
KAAPVKASKVVDTVGAGDGFNAGILYGYLHDWSLERTLTFGNTIGSMVVGITGDNEGLPY
EECCCCHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCEEEEEECCCCCCCC
YEDVQERLGEIERIER
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKDIITLGEAMVVFNPASTGPMKFVNGFHKTIGGAELNLAIGCARLGLDTGYITRLGNDE
CCCCEECCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEEHHHHCCCCCCEEECCCHH
FGKSIRNFVRGEGIDASEIDFIDHYPTSINFKEIMEDGSVRTFYYRDKSPTLSMTPDVLN
HHHHHHHHHCCCCCCHHHCCHHHCCCCCCCHHHHHCCCCEEEEEEECCCCCEECCHHHHH
ESYFKNAKILHLTGIFPAIGEGALKVWKQAIHLAKKHGVKISFDPNIRLKMWSKEQARKV
HHHHCCCEEEEEECCCCHHCHHHHHHHHHHHHHHHHCCEEEEECCCEEEEECCHHHHHHH
LLEILPDVDILLAGDEEMDIIIGKRDPVDIIETCKELGIPYVAIKQGENGSVGYSQGETM
HHHHCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCE
KAAPVKASKVVDTVGAGDGFNAGILYGYLHDWSLERTLTFGNTIGSMVVGITGDNEGLPY
EECCCCHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCEEEEEECCCCCCCC
YEDVQERLGEIERIER
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]