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The map label for this gene is pgm

Identifier: 23099890

GI number: 23099890

Start: 2489858

End: 2491396

Strand: Reverse

Name: pgm

Synonym: OB2435

Alternate gene names: 23099890

Gene position: 2491396-2489858 (Counterclockwise)

Preceding gene: 23099891

Following gene: 23099889

Centisome position: 68.62

GC content: 36.06

Gene sequence:

>1539_bases
ATGAGTCAGAATAAATTAGCTGCATTAATTATTCTTGATGGATTCGCTATTCGTGATGAAGTAAAAGGAAATGCAGTCAA
ACAAGCAAACACCCCTAATTTTGATCGTTTTTGGAATCAATATGCTCATAATCAATTAGAGGCTTCTGGAAAGGCTGTTG
GATTACCAGATGGGCAAATGGGGAATTCCGAAGTTGGTCATTTGAATATTGGTGCTGGTCGTATTGTGTATCAAAGCCTT
ACTCGTGTAAATGTGTCTATTGACGAAGGTGATTTCTATGAGGTTGATGCGTTCATTAAATCTGTAGAACATGCAAAGAA
ACATGACAAAGCGCTTCACTTATTTGGTTTATTATCTGACGGTGGTGTGCATAGTCATATTAATCATTTATTTGCTTTAC
TTCGATTAGCGAAGAAACATGAATTAGAAAATGTATTTGTACATGCTTTCTTAGACGGACGTGATGTTGGTCCGAAAACA
GCGAGCAAATATATCAAAGAAACACAAGATGTGATGGATGAACTTGGTGTTGGTCAATTCGCTACTATATCTGGTCGTTA
CTATTCCATGGATCGTGACAAACGTTGGGACCGTGTAAAGAAATGTTATGACGCAATGGTATACGGTGAAGGTCCATCAT
ATAAAAGTGCACAAGAAGTTGTAGATGATAACTATGCAAATGAAATTTATGATGAGTTTGTAATTCCTTCTGTAATTACA
GATGACAATGATGAACCAGTGGCTACGATTAAGGATGAAGATTCTATTATCTTCTATAATTTCCGTCCTGATCGTGCGAT
ACAAATCTCTAGAACATTTGCGAATGAGGATTTTCGTGACTTTGAGCGAGGCGATAAAGCTCCAAAAAAACTAGACTTTG
TAATGCTGACAAACTTTAGTGAAACAGTAGATGGATATGTTGCGTATCAACCAGTCAATCTAGATAATACTGTTGGAGAA
GTTCTAGCACAAAATAATTTGAATCAATTACGTATTGCAGAAACGGAGAAATATCCACACGTTACTTTCTTTATGAGTGG
TGGACGCGAAAAAGAATTCCCTGGTGAAAAAAGGATTTTAATTGACTCACCCAAAGTAGCAACCTATGATCTGAAACCTG
AAATGAGTGTATATGAAGTTACTGATGCACTGTTAAAGGAATTAGATAAAGGGGAGCAGAATGCGATTATCTTGAATTTT
GCTAATCCAGATATGGTTGGACATTCAGGGAAATTACAACCAACTATTGATGCTATTGAAGCAGTGGATGAATGTTTAGG
TAAGGTAATTGATAAAATTACTGAATTAGGTGGTCATGCCATAATAACTGCAGATCACGGCAACTCTGATGAAGTTATGA
CTTTGGAAGATAAACCAATGACAGCTCACACAACTAACCCTGTACCTGTTATTGTAACCAAAGATGATATTGAGTTACGT
GATGGTGGAATTTTAGCAGATTTATCACCAACACTGCTTGATTTATTAAATGTTGAAAAACCAAAAGAAATGACTGGCAA
TAGTCTTATAAAAAAATAA

Upstream 100 bases:

>100_bases
TGGATGAGTTATTAGCTCAATCTGATATTGACGGAGCATTAGTTGGTGGGGCAAGTCTCGATCCTGAATCATTCCTACAA
CTAGTGGAGGCAGGTACAAA

Downstream 100 bases:

>100_bases
TAAAACAATAAGGAGAGAATAATATGCCATATATTACAGATGTTTATGCTAGAGAAGTCTTAGATTCAAGAGGTAACCCA
ACCATTGAAGTTGAAATTTT

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MSQNKLAALIILDGFAIRDEVKGNAVKQANTPNFDRFWNQYAHNQLEASGKAVGLPDGQMGNSEVGHLNIGAGRIVYQSL
TRVNVSIDEGDFYEVDAFIKSVEHAKKHDKALHLFGLLSDGGVHSHINHLFALLRLAKKHELENVFVHAFLDGRDVGPKT
ASKYIKETQDVMDELGVGQFATISGRYYSMDRDKRWDRVKKCYDAMVYGEGPSYKSAQEVVDDNYANEIYDEFVIPSVIT
DDNDEPVATIKDEDSIIFYNFRPDRAIQISRTFANEDFRDFERGDKAPKKLDFVMLTNFSETVDGYVAYQPVNLDNTVGE
VLAQNNLNQLRIAETEKYPHVTFFMSGGREKEFPGEKRILIDSPKVATYDLKPEMSVYEVTDALLKELDKGEQNAIILNF
ANPDMVGHSGKLQPTIDAIEAVDECLGKVIDKITELGGHAIITADHGNSDEVMTLEDKPMTAHTTNPVPVIVTKDDIELR
DGGILADLSPTLLDLLNVEKPKEMTGNSLIKK

Sequences:

>Translated_512_residues
MSQNKLAALIILDGFAIRDEVKGNAVKQANTPNFDRFWNQYAHNQLEASGKAVGLPDGQMGNSEVGHLNIGAGRIVYQSL
TRVNVSIDEGDFYEVDAFIKSVEHAKKHDKALHLFGLLSDGGVHSHINHLFALLRLAKKHELENVFVHAFLDGRDVGPKT
ASKYIKETQDVMDELGVGQFATISGRYYSMDRDKRWDRVKKCYDAMVYGEGPSYKSAQEVVDDNYANEIYDEFVIPSVIT
DDNDEPVATIKDEDSIIFYNFRPDRAIQISRTFANEDFRDFERGDKAPKKLDFVMLTNFSETVDGYVAYQPVNLDNTVGE
VLAQNNLNQLRIAETEKYPHVTFFMSGGREKEFPGEKRILIDSPKVATYDLKPEMSVYEVTDALLKELDKGEQNAIILNF
ANPDMVGHSGKLQPTIDAIEAVDECLGKVIDKITELGGHAIITADHGNSDEVMTLEDKPMTAHTTNPVPVIVTKDDIELR
DGGILADLSPTLLDLLNVEKPKEMTGNSLIKK
>Mature_511_residues
SQNKLAALIILDGFAIRDEVKGNAVKQANTPNFDRFWNQYAHNQLEASGKAVGLPDGQMGNSEVGHLNIGAGRIVYQSLT
RVNVSIDEGDFYEVDAFIKSVEHAKKHDKALHLFGLLSDGGVHSHINHLFALLRLAKKHELENVFVHAFLDGRDVGPKTA
SKYIKETQDVMDELGVGQFATISGRYYSMDRDKRWDRVKKCYDAMVYGEGPSYKSAQEVVDDNYANEIYDEFVIPSVITD
DNDEPVATIKDEDSIIFYNFRPDRAIQISRTFANEDFRDFERGDKAPKKLDFVMLTNFSETVDGYVAYQPVNLDNTVGEV
LAQNNLNQLRIAETEKYPHVTFFMSGGREKEFPGEKRILIDSPKVATYDLKPEMSVYEVTDALLKELDKGEQNAIILNFA
NPDMVGHSGKLQPTIDAIEAVDECLGKVIDKITELGGHAIITADHGNSDEVMTLEDKPMTAHTTNPVPVIVTKDDIELRD
GGILADLSPTLLDLLNVEKPKEMTGNSLIKK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=513, Percent_Identity=46.588693957115, Blast_Score=471, Evalue=1e-134,
Organism=Caenorhabditis elegans, GI32564249, Length=513, Percent_Identity=38.401559454191, Blast_Score=394, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17507741, Length=513, Percent_Identity=38.401559454191, Blast_Score=394, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_OCEIH (P59174)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693356.1
- ProteinModelPortal:   P59174
- SMR:   P59174
- GeneID:   1017222
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2435
- NMPDR:   fig|221109.1.peg.2432
- HOGENOM:   HBG613255
- OMA:   DHGNAEL
- ProtClustDB:   PRK05434
- BioCyc:   OIHE221109:OB2435-MONOMER
- BRENDA:   5.4.2.1
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 57179; Mature: 57048

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: ACT_SITE 63-63

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNKLAALIILDGFAIRDEVKGNAVKQANTPNFDRFWNQYAHNQLEASGKAVGLPDGQM
CCCCCEEEEEEECCEEEEHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCC
GNSEVGHLNIGAGRIVYQSLTRVNVSIDEGDFYEVDAFIKSVEHAKKHDKALHLFGLLSD
CCCCCCEEECCCCHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHCCEEEEEEEECC
GGVHSHINHLFALLRLAKKHELENVFVHAFLDGRDVGPKTASKYIKETQDVMDELGVGQF
CCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCE
ATISGRYYSMDRDKRWDRVKKCYDAMVYGEGPSYKSAQEVVDDNYANEIYDEFVIPSVIT
EEECCEEEECCCHHHHHHHHHHHHHEEECCCCCCCHHHHHHCCCHHHHHHHHHCCCCEEE
DDNDEPVATIKDEDSIIFYNFRPDRAIQISRTFANEDFRDFERGDKAPKKLDFVMLTNFS
CCCCCCEEEEECCCCEEEEEECCCCEEEEEEHHCCCCHHHHHHCCCCCCCEEEEEEECCC
ETVDGYVAYQPVNLDNTVGEVLAQNNLNQLRIAETEKYPHVTFFMSGGREKEFPGEKRIL
CCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCEEE
IDSPKVATYDLKPEMSVYEVTDALLKELDKGEQNAIILNFANPDMVGHSGKLQPTIDAIE
EECCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHH
AVDECLGKVIDKITELGGHAIITADHGNSDEVMTLEDKPMTAHTTNPVPVIVTKDDIELR
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCCEEECCCCEEEEEECCCCEEC
DGGILADLSPTLLDLLNVEKPKEMTGNSLIKK
CCCEEECCCHHHHHHHCCCCCHHHCCHHHCCC
>Mature Secondary Structure 
SQNKLAALIILDGFAIRDEVKGNAVKQANTPNFDRFWNQYAHNQLEASGKAVGLPDGQM
CCCCEEEEEEECCEEEEHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCC
GNSEVGHLNIGAGRIVYQSLTRVNVSIDEGDFYEVDAFIKSVEHAKKHDKALHLFGLLSD
CCCCCCEEECCCCHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHCCEEEEEEEECC
GGVHSHINHLFALLRLAKKHELENVFVHAFLDGRDVGPKTASKYIKETQDVMDELGVGQF
CCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCE
ATISGRYYSMDRDKRWDRVKKCYDAMVYGEGPSYKSAQEVVDDNYANEIYDEFVIPSVIT
EEECCEEEECCCHHHHHHHHHHHHHEEECCCCCCCHHHHHHCCCHHHHHHHHHCCCCEEE
DDNDEPVATIKDEDSIIFYNFRPDRAIQISRTFANEDFRDFERGDKAPKKLDFVMLTNFS
CCCCCCEEEEECCCCEEEEEECCCCEEEEEEHHCCCCHHHHHHCCCCCCCEEEEEEECCC
ETVDGYVAYQPVNLDNTVGEVLAQNNLNQLRIAETEKYPHVTFFMSGGREKEFPGEKRIL
CCCCCEEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCEEE
IDSPKVATYDLKPEMSVYEVTDALLKELDKGEQNAIILNFANPDMVGHSGKLQPTIDAIE
EECCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHH
AVDECLGKVIDKITELGGHAIITADHGNSDEVMTLEDKPMTAHTTNPVPVIVTKDDIELR
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCCEEECCCCEEEEEECCCCEEC
DGGILADLSPTLLDLLNVEKPKEMTGNSLIKK
CCCEEECCCHHHHHHHCCCCCHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376