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The map label for this gene is helD [H]

Identifier: 23099747

GI number: 23099747

Start: 2336473

End: 2338788

Strand: Reverse

Name: helD [H]

Synonym: OB2292

Alternate gene names: 23099747

Gene position: 2338788-2336473 (Counterclockwise)

Preceding gene: 23099748

Following gene: 23099744

Centisome position: 64.42

GC content: 33.16

Gene sequence:

>2316_bases
ATGAGTTCTTCCAACAATAATGAACATATTTTTGAGCATCAACGTTTAGACCGTATTCTTCAAATAATTGAGGATAGGGA
AAATGCAATTACACAGCAATCTTCAAAAATTAAACAGGAAGTCGTAGAATTTAGAAAAAACTTTTGGGATGATATTACAA
TTAATTTAGAAGAAATGGATGATGTAATAGAAACACAAGAAAGTATTAAACAACAATCTAGTGTTTTAGCACAAAAAGAG
AGACATTACGGTAAGAATTATCAGCGGCTAAAACAATTGCAAAGATTAAAAAGTCAACCTTATTTTGGAAGAGTAGATTT
TAAGGATGCAACTGAAAGTGATGAAAATCAAATCTATATTGGTACTTCGTCTTTAATGGATGAAGAGGGCTCTGATTTCT
ACATTTATGATTGGAGAGCACCGATTTCAAGTATTTATTATGATTATGCACCTGGACCTGTTGAGTATGAAACCGAAGAA
GAATTCGTAAAAGGGGAAATGACTTTAAAACGGCAATTTGTTATAAGGCAAGGAAAAATGAAAGGTATTTTTGATACAGC
TGTAACGATAGTTGATGAATTGCTTCAAGAAAGCTTGAGTCAGTCGGCCAATGCAACAATGAAGTCAATTGTTGCAACTA
TTCAACAAGAGCAAAATAGAATTATTCGTCATCAAGGTAGTAAAATTTTAGTTGTACAAGGTGCAGCAGGAAGTGGAAAG
ACAGCGGCTGCTTTACAAAGAATTGCCTATTTATTATACCACCATCGTTCAAGTTTACAGGCAAATCAAGTACTGCTGCT
ATCACCAAATGATATATTCTCAAGTTATATTTCTAACGTACTCCCCGAGTTAGGTGAAGAGCCAGTGAATCAACAAACGT
TCTATAATTTTCTTATAAAAGGGCTGGAAAGTAACTTAAAAGTGGAGACACCTTTTGAACAAATGGAACTATTATTAATA
GGTGAAGATAAACAACAAAAAGAAAACGCAGTAAAGTTTTTTACAAGCATACAATTTATGAAAGATATTCAATCGTATTT
ATCCTTTATAAATAAAGATGGTTTGCAGTTTCGACATATTCGATTTCGAAATGAACTCCTTATTTCAAAAGAAGAAATCA
ATACGTACTTTCATGAGCTTCCTAAATCCATGAAGTTATCAAATAAAATTGAAAAGATACAACGTTGGTTATTACAAAAA
ATAAAAGAGATTCAGGTCAAAGAAATTGCAGCAAATTGGGTGCAAGATCAAATGGAATTATTAAAAAAAGAAGATTATAT
GGAAGCTTATCATGAGGCTGAAGCTGAGGAAGAGGAAAGTTCCATTCAAGATGAAGAGTTAATTTTACGCAAAAAAATAG
TGTATAAAGCATTTGCACCGTTAACAAAGAGTATAAAACAAAATCGTTTTGTACACACATTACGAATGTATACAAAATTA
TTCAACCAATGGGCGCCTTTGGACAGAGAGAATGAATGGAAAACATATTCGAAGTATGTACTATGTGACCTTCAACAGAA
TAAATTGCCCTGGGAGCATGCAGTAGCATATCGATTTTTTAAAGGAGAAATAATAGGTCATGATGTTGATCAACCAACAC
GATTGATTGTGATTGATGAAGCACAGGATTATACACCATTTCAATTCGCTTATTTACAGCATGTGTATCCTTATGGAAGA
ATGACGTTACTAGGTGATATTAATCAATCAATTTATTCCTATGCGTCTAAGGATAATCCAATTCAGGAACAAGCAGACTC
AAAAGATATCGAACGTATAGTATTAACCAAGAGTTATCGATCGACTAAGCCTATAACCGATTTCACCACTTATTTCGCAC
CAAGTAATGAAGGTATAAGTGCTTTTGAGCGTCATGGAACACTACCTTCTGTAATTCAACTACCGGAAGAATCTAATTAT
AAGAATGCGCTGCTGGAGATGATTGAAACCAGGAAAAAAGAGGGCCATGAAACAATTGCTGTGATATGTAAATCAATGCA
GGAATGTAAGAAATATAAGAAGTTACTGGATGAGGATGTAGAGATTAATCTTGTTCGTACGAATACGAAGGAATATCAAC
ATGGTGTAGTTTTTATACCAGTTTATTTGGCTAAAGGTATTGAATTTGACGCTGTCATTATTCCTGACGCATCTGAAACT
AACTACCACACCGAAAAAGATAGGTATTTATTCTATACTGCCTGTACAAGAGCAATGCATGATTTAACAACAGTTTTTAT
GGATAAACCAAGTCCATTTATAAAAGAAATACCAAAAGAAAGATACTCATTTAGAACAATATTTGAAAGAAATTAG

Upstream 100 bases:

>100_bases
TCATATTAATTGATTTTTGTATAAACTATTCCTAATTATATTATAAGGTCAATTAAATGATTTGTCAACAAATACATCAT
ATTTAATTAGGGGGATATTT

Downstream 100 bases:

>100_bases
AGTTTTAGGGTCTGGGACATAACTAAGACCTTTATGGTTAAAACCAATTGGTAATTCTAAATAATTATGTCCCAGCCATT
TTATATTTATCCTTGTACTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 771; Mature: 770

Protein sequence:

>771_residues
MSSSNNNEHIFEHQRLDRILQIIEDRENAITQQSSKIKQEVVEFRKNFWDDITINLEEMDDVIETQESIKQQSSVLAQKE
RHYGKNYQRLKQLQRLKSQPYFGRVDFKDATESDENQIYIGTSSLMDEEGSDFYIYDWRAPISSIYYDYAPGPVEYETEE
EFVKGEMTLKRQFVIRQGKMKGIFDTAVTIVDELLQESLSQSANATMKSIVATIQQEQNRIIRHQGSKILVVQGAAGSGK
TAAALQRIAYLLYHHRSSLQANQVLLLSPNDIFSSYISNVLPELGEEPVNQQTFYNFLIKGLESNLKVETPFEQMELLLI
GEDKQQKENAVKFFTSIQFMKDIQSYLSFINKDGLQFRHIRFRNELLISKEEINTYFHELPKSMKLSNKIEKIQRWLLQK
IKEIQVKEIAANWVQDQMELLKKEDYMEAYHEAEAEEEESSIQDEELILRKKIVYKAFAPLTKSIKQNRFVHTLRMYTKL
FNQWAPLDRENEWKTYSKYVLCDLQQNKLPWEHAVAYRFFKGEIIGHDVDQPTRLIVIDEAQDYTPFQFAYLQHVYPYGR
MTLLGDINQSIYSYASKDNPIQEQADSKDIERIVLTKSYRSTKPITDFTTYFAPSNEGISAFERHGTLPSVIQLPEESNY
KNALLEMIETRKKEGHETIAVICKSMQECKKYKKLLDEDVEINLVRTNTKEYQHGVVFIPVYLAKGIEFDAVIIPDASET
NYHTEKDRYLFYTACTRAMHDLTTVFMDKPSPFIKEIPKERYSFRTIFERN

Sequences:

>Translated_771_residues
MSSSNNNEHIFEHQRLDRILQIIEDRENAITQQSSKIKQEVVEFRKNFWDDITINLEEMDDVIETQESIKQQSSVLAQKE
RHYGKNYQRLKQLQRLKSQPYFGRVDFKDATESDENQIYIGTSSLMDEEGSDFYIYDWRAPISSIYYDYAPGPVEYETEE
EFVKGEMTLKRQFVIRQGKMKGIFDTAVTIVDELLQESLSQSANATMKSIVATIQQEQNRIIRHQGSKILVVQGAAGSGK
TAAALQRIAYLLYHHRSSLQANQVLLLSPNDIFSSYISNVLPELGEEPVNQQTFYNFLIKGLESNLKVETPFEQMELLLI
GEDKQQKENAVKFFTSIQFMKDIQSYLSFINKDGLQFRHIRFRNELLISKEEINTYFHELPKSMKLSNKIEKIQRWLLQK
IKEIQVKEIAANWVQDQMELLKKEDYMEAYHEAEAEEEESSIQDEELILRKKIVYKAFAPLTKSIKQNRFVHTLRMYTKL
FNQWAPLDRENEWKTYSKYVLCDLQQNKLPWEHAVAYRFFKGEIIGHDVDQPTRLIVIDEAQDYTPFQFAYLQHVYPYGR
MTLLGDINQSIYSYASKDNPIQEQADSKDIERIVLTKSYRSTKPITDFTTYFAPSNEGISAFERHGTLPSVIQLPEESNY
KNALLEMIETRKKEGHETIAVICKSMQECKKYKKLLDEDVEINLVRTNTKEYQHGVVFIPVYLAKGIEFDAVIIPDASET
NYHTEKDRYLFYTACTRAMHDLTTVFMDKPSPFIKEIPKERYSFRTIFERN
>Mature_770_residues
SSSNNNEHIFEHQRLDRILQIIEDRENAITQQSSKIKQEVVEFRKNFWDDITINLEEMDDVIETQESIKQQSSVLAQKER
HYGKNYQRLKQLQRLKSQPYFGRVDFKDATESDENQIYIGTSSLMDEEGSDFYIYDWRAPISSIYYDYAPGPVEYETEEE
FVKGEMTLKRQFVIRQGKMKGIFDTAVTIVDELLQESLSQSANATMKSIVATIQQEQNRIIRHQGSKILVVQGAAGSGKT
AAALQRIAYLLYHHRSSLQANQVLLLSPNDIFSSYISNVLPELGEEPVNQQTFYNFLIKGLESNLKVETPFEQMELLLIG
EDKQQKENAVKFFTSIQFMKDIQSYLSFINKDGLQFRHIRFRNELLISKEEINTYFHELPKSMKLSNKIEKIQRWLLQKI
KEIQVKEIAANWVQDQMELLKKEDYMEAYHEAEAEEEESSIQDEELILRKKIVYKAFAPLTKSIKQNRFVHTLRMYTKLF
NQWAPLDRENEWKTYSKYVLCDLQQNKLPWEHAVAYRFFKGEIIGHDVDQPTRLIVIDEAQDYTPFQFAYLQHVYPYGRM
TLLGDINQSIYSYASKDNPIQEQADSKDIERIVLTKSYRSTKPITDFTTYFAPSNEGISAFERHGTLPSVIQLPEESNYK
NALLEMIETRKKEGHETIAVICKSMQECKKYKKLLDEDVEINLVRTNTKEYQHGVVFIPVYLAKGIEFDAVIIPDASETN
YHTEKDRYLFYTACTRAMHDLTTVFMDKPSPFIKEIPKERYSFRTIFERN

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 90436; Mature: 90304

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSNNNEHIFEHQRLDRILQIIEDRENAITQQSSKIKQEVVEFRKNFWDDITINLEEMD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHH
DVIETQESIKQQSSVLAQKERHYGKNYQRLKQLQRLKSQPYFGRVDFKDATESDENQIYI
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
GTSSLMDEEGSDFYIYDWRAPISSIYYDYAPGPVEYETEEEFVKGEMTLKRQFVIRQGKM
ECHHHHCCCCCCEEEEECCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
KGIFDTAVTIVDELLQESLSQSANATMKSIVATIQQEQNRIIRHQGSKILVVQGAAGSGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCH
TAAALQRIAYLLYHHRSSLQANQVLLLSPNDIFSSYISNVLPELGEEPVNQQTFYNFLIK
HHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
GLESNLKVETPFEQMELLLIGEDKQQKENAVKFFTSIQFMKDIQSYLSFINKDGLQFRHI
HHCCCCEEECCHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
RFRNELLISKEEINTYFHELPKSMKLSNKIEKIQRWLLQKIKEIQVKEIAANWVQDQMEL
EHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKKEDYMEAYHEAEAEEEESSIQDEELILRKKIVYKAFAPLTKSIKQNRFVHTLRMYTKL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNQWAPLDRENEWKTYSKYVLCDLQQNKLPWEHAVAYRFFKGEIIGHDVDQPTRLIVIDE
HHHCCCCCCCCCCHHHHCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
AQDYTPFQFAYLQHVYPYGRMTLLGDINQSIYSYASKDNPIQEQADSKDIERIVLTKSYR
CCCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHCCCCC
STKPITDFTTYFAPSNEGISAFERHGTLPSVIQLPEESNYKNALLEMIETRKKEGHETIA
CCCCCHHHHHEECCCCCCHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHH
VICKSMQECKKYKKLLDEDVEINLVRTNTKEYQHGVVFIPVYLAKGIEFDAVIIPDASET
HHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHCCEEEEEHHHHCCCCCCEEEECCCCCC
NYHTEKDRYLFYTACTRAMHDLTTVFMDKPSPFIKEIPKERYSFRTIFERN
CCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSSNNNEHIFEHQRLDRILQIIEDRENAITQQSSKIKQEVVEFRKNFWDDITINLEEMD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHH
DVIETQESIKQQSSVLAQKERHYGKNYQRLKQLQRLKSQPYFGRVDFKDATESDENQIYI
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEE
GTSSLMDEEGSDFYIYDWRAPISSIYYDYAPGPVEYETEEEFVKGEMTLKRQFVIRQGKM
ECHHHHCCCCCCEEEEECCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
KGIFDTAVTIVDELLQESLSQSANATMKSIVATIQQEQNRIIRHQGSKILVVQGAAGSGK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCH
TAAALQRIAYLLYHHRSSLQANQVLLLSPNDIFSSYISNVLPELGEEPVNQQTFYNFLIK
HHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
GLESNLKVETPFEQMELLLIGEDKQQKENAVKFFTSIQFMKDIQSYLSFINKDGLQFRHI
HHCCCCEEECCHHHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
RFRNELLISKEEINTYFHELPKSMKLSNKIEKIQRWLLQKIKEIQVKEIAANWVQDQMEL
EHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKKEDYMEAYHEAEAEEEESSIQDEELILRKKIVYKAFAPLTKSIKQNRFVHTLRMYTKL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FNQWAPLDRENEWKTYSKYVLCDLQQNKLPWEHAVAYRFFKGEIIGHDVDQPTRLIVIDE
HHHCCCCCCCCCCHHHHCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEC
AQDYTPFQFAYLQHVYPYGRMTLLGDINQSIYSYASKDNPIQEQADSKDIERIVLTKSYR
CCCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHCCCCC
STKPITDFTTYFAPSNEGISAFERHGTLPSVIQLPEESNYKNALLEMIETRKKEGHETIA
CCCCCHHHHHEECCCCCCHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHH
VICKSMQECKKYKKLLDEDVEINLVRTNTKEYQHGVVFIPVYLAKGIEFDAVIIPDASET
HHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHCCEEEEEHHHHCCCCCCEEEECCCCCC
NYHTEKDRYLFYTACTRAMHDLTTVFMDKPSPFIKEIPKERYSFRTIFERN
CCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]