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The map label for this gene is rnhC

Identifier: 23099583

GI number: 23099583

Start: 2162847

End: 2163773

Strand: Direct

Name: rnhC

Synonym: OB2128

Alternate gene names: 23099583

Gene position: 2162847-2163773 (Clockwise)

Preceding gene: 23099570

Following gene: 23099584

Centisome position: 59.57

GC content: 36.14

Gene sequence:

>927_bases
ATGAGCCAACAAGTAATTGTAACTACTAAGGAACAAATTCAAAAAATGAAGAAATATTATCTTTCGCAGTTAACATCAAC
CCCCCAAGGTGCTATTTTTCGTGCAAAAACGAATAACGCAGTAATCACTGCTTATCAATCAGGTAAAGTTCTTTTCCAAG
GATCTGCACCGGAATCCGAAGCATCGAAGTGGGGTAACGTTCCTTTAAATGATAAAAAGAAACATTCGTTAGAACAAAAA
CACTCATATTCTCCACAAGCGGAATTATTTACTGACAATCATATCGGCTCTGATGAAGCGGGTACAGGTGATTACTTTGG
GCCCATTACAGTAGCAGCATTATTTGCAACAAAAGAGCAACAATTAAAGCTAAAACAAATAGGTGTACGTGATTCAAAGC
ATTTAAACGATACAAAAATTAAACAAATTGCTAAGGAGATTGCTCATTTACAAATTCCCTATTCTCTCCTTTTGCTCCCG
AATGGAAAATATAATAAATTACAGGCAAAAGGTTGGTCCCAAGGAAAAATGAAAGCAATGCTGCATCATCATGCTATTGA
TAAATTATTGCAAAAAATCGATGTCAGATCCTTAAAAGGTATTGTGATCGATCAATTTTGCCAACCTCCTGTTTACAAAA
AATATTTACAATCAGAGAAAAAAACGCTCCATCCGAACACGACTTTTATTACGAAAGCAGAAAGTCATTCTATTAGTGTG
GCAGCTGCTTCCATATTGGCTAGAGCAAGATTTGTAAATGCAATGGATGAACTATCTGAAGAAGCAAAAATGGAACTACC
TAAAGGAGCTTCCGCAAAGGTTGATCAAACGGCAGCCAGACTTATTCGTTCTAAAGGTTTCGAAGAACTTGATAAATATG
CGAAAACGCATTTTGCTAATACGCAGAAGGCACAAAAATTACTGTAA

Upstream 100 bases:

>100_bases
ATATAATAGTAACATGAAGTTCTTATAAAAAGAAGTATTTCAATGAATCAATCATTTTGCTATAGTCTAATGTATGTAAG
GATTGGAGAGATGTCAAAAA

Downstream 100 bases:

>100_bases
GGATGATATTAATGGAAAACCCTTTATATAATGATTGGTCCCTTTTATTAGAGGATGAGTTCAAAAAAGACTACTACCTA
AGATTAAGAAGTTTCTTAAA

Product: ribonuclease HIII

Products: NA

Alternate protein names: RNase HIII

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSQQVIVTTKEQIQKMKKYYLSQLTSTPQGAIFRAKTNNAVITAYQSGKVLFQGSAPESEASKWGNVPLNDKKKHSLEQK
HSYSPQAELFTDNHIGSDEAGTGDYFGPITVAALFATKEQQLKLKQIGVRDSKHLNDTKIKQIAKEIAHLQIPYSLLLLP
NGKYNKLQAKGWSQGKMKAMLHHHAIDKLLQKIDVRSLKGIVIDQFCQPPVYKKYLQSEKKTLHPNTTFITKAESHSISV
AAASILARARFVNAMDELSEEAKMELPKGASAKVDQTAARLIRSKGFEELDKYAKTHFANTQKAQKLL

Sequences:

>Translated_308_residues
MSQQVIVTTKEQIQKMKKYYLSQLTSTPQGAIFRAKTNNAVITAYQSGKVLFQGSAPESEASKWGNVPLNDKKKHSLEQK
HSYSPQAELFTDNHIGSDEAGTGDYFGPITVAALFATKEQQLKLKQIGVRDSKHLNDTKIKQIAKEIAHLQIPYSLLLLP
NGKYNKLQAKGWSQGKMKAMLHHHAIDKLLQKIDVRSLKGIVIDQFCQPPVYKKYLQSEKKTLHPNTTFITKAESHSISV
AAASILARARFVNAMDELSEEAKMELPKGASAKVDQTAARLIRSKGFEELDKYAKTHFANTQKAQKLL
>Mature_307_residues
SQQVIVTTKEQIQKMKKYYLSQLTSTPQGAIFRAKTNNAVITAYQSGKVLFQGSAPESEASKWGNVPLNDKKKHSLEQKH
SYSPQAELFTDNHIGSDEAGTGDYFGPITVAALFATKEQQLKLKQIGVRDSKHLNDTKIKQIAKEIAHLQIPYSLLLLPN
GKYNKLQAKGWSQGKMKAMLHHHAIDKLLQKIDVRSLKGIVIDQFCQPPVYKKYLQSEKKTLHPNTTFITKAESHSISVA
AASILARARFVNAMDELSEEAKMELPKGASAKVDQTAARLIRSKGFEELDKYAKTHFANTQKAQKLL

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG1039

COG function: function code L; Ribonuclease HIII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family. RnhC subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH3_OCEIH (Q8EPH7)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_693049.1
- ProteinModelPortal:   Q8EPH7
- SMR:   Q8EPH7
- GeneID:   1015639
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB2128
- NMPDR:   fig|221109.1.peg.2126
- HOGENOM:   HBG288559
- OMA:   ASIIARY
- ProtClustDB:   PRK00996
- BioCyc:   OIHE221109:OB2128-MONOMER
- BRENDA:   3.1.26.4
- GO:   GO:0005737
- HAMAP:   MF_00053
- InterPro:   IPR001352
- InterPro:   IPR004641
- InterPro:   IPR012337
- PIRSF:   PIRSF037748
- TIGRFAMs:   TIGR00716

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 34433; Mature: 34302

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQVIVTTKEQIQKMKKYYLSQLTSTPQGAIFRAKTNNAVITAYQSGKVLFQGSAPESE
CCCCEEEECHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEECCCEEEECCCCHHH
ASKWGNVPLNDKKKHSLEQKHSYSPQAELFTDNHIGSDEAGTGDYFGPITVAALFATKEQ
HHHCCCCCCCCCHHHHHHHHHCCCCCHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
QLKLKQIGVRDSKHLNDTKIKQIAKEIAHLQIPYSLLLLPNGKYNKLQAKGWSQGKMKAM
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEECCCCCCHHHHHH
LHHHAIDKLLQKIDVRSLKGIVIDQFCQPPVYKKYLQSEKKTLHPNTTFITKAESHSISV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHH
AAASILARARFVNAMDELSEEAKMELPKGASAKVDQTAARLIRSKGFEELDKYAKTHFAN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCC
TQKAQKLL
HHHHHHCC
>Mature Secondary Structure 
SQQVIVTTKEQIQKMKKYYLSQLTSTPQGAIFRAKTNNAVITAYQSGKVLFQGSAPESE
CCCEEEECHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEEEECCCEEEECCCCHHH
ASKWGNVPLNDKKKHSLEQKHSYSPQAELFTDNHIGSDEAGTGDYFGPITVAALFATKEQ
HHHCCCCCCCCCHHHHHHHHHCCCCCHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHH
QLKLKQIGVRDSKHLNDTKIKQIAKEIAHLQIPYSLLLLPNGKYNKLQAKGWSQGKMKAM
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEECCCCCCHHHHHH
LHHHAIDKLLQKIDVRSLKGIVIDQFCQPPVYKKYLQSEKKTLHPNTTFITKAESHSISV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHH
AAASILARARFVNAMDELSEEAKMELPKGASAKVDQTAARLIRSKGFEELDKYAKTHFAN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCC
TQKAQKLL
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376