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The map label for this gene is prmA

Identifier: 23099421

GI number: 23099421

Start: 1993080

End: 1994027

Strand: Reverse

Name: prmA

Synonym: OB1966

Alternate gene names: 23099421

Gene position: 1994027-1993080 (Counterclockwise)

Preceding gene: 23099422

Following gene: 23099420

Centisome position: 54.92

GC content: 35.86

Gene sequence:

>948_bases
ATGAAATGGTCAGAGATAAGTATTCATACAACAAACGAGGCGATTGAACCAATTTCGAATATTTTACATGAAACAGGTGC
AAGTGGTCTTGTTATTGAGGATCCATTAGATCTCGAGAGGGTGGAGAAAGCTGAATTTGGGGAACTTTATGATCTTGACC
CGGCGCTATACCCTGAAGAGGGAGTACGTATTAAAGCATATCTTCCTATGAATAGTTTTTTAGGAGAAACAGTTGAAGAA
ATAAAGTCTGCTATTAATCAATTGTTGATTTATGATATTGACTTAGGTAAGAATGAAGTCTCGTTGAGTGAGGTTCATGA
AGAAGAATGGGCAACGGCTTGGAAGAAATATTATAAACCAGTTAAAATATCAAATCGAATCACAATTACTCCTACATGGG
AAGAGTATACACCAGTATCTAGTGATGAATTGATTATCGAATTAGATCCAGGTATGGCTTTTGGTACTGGCACACATCCA
ACTACAGTCCTTAGTATTCAAGGATTAGAGGCGTATGTGAAACCAGGAGATTTAGTAATGGATGTAGGTTGTGGATCAGG
GGTTTTAAGTATTGCAGCTGCCAAATTAGGTGCAGATAAAGTAAATGCTTATGATCTTGATGAAATTGCTGTAAAAAGTA
CAAAATTAAACTCCAAGTTAAATCAGATCCATGAGTCTGTTAAGGTGAAACAAAATAACTTGCTAGAAGGTGTTCAGCAA
GAGGCGGATGTTATTGTATCCAATATTTTAGCGGAAATTATCGTACGTTTTGTCGATGATGCATGGAGTAATTTAAAAGC
AGGCGGATATTTTATCACTTCTGGAATAATTCAAAACAAAAAACAACTTGTTATAGATAATTTAACAAAACAAGGATTTG
AAGTTATATCTCTAAACGAGATGGAAGACTGGGTTTCGATTGTCGCTAAGAAGCCAAGTGAAAAGTAG

Upstream 100 bases:

>100_bases
TATTTTCCAACGATTTCGTAGAGCTTTTAAAGGAGAATAACGGCGCAAATTTTGCGCCGTTTACATAGATATTTTTCCAT
TAGACGGGTGGTAACCACAA

Downstream 100 bases:

>100_bases
GTGAAACGATGCAAAGATACTTTGTATCCCAAGAAAATGTCACTGAGAACTCCATACGAATCATTGGAGATGATGTCCAT
CATATTCAACGAGTAATGCG

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKWSEISIHTTNEAIEPISNILHETGASGLVIEDPLDLERVEKAEFGELYDLDPALYPEEGVRIKAYLPMNSFLGETVEE
IKSAINQLLIYDIDLGKNEVSLSEVHEEEWATAWKKYYKPVKISNRITITPTWEEYTPVSSDELIIELDPGMAFGTGTHP
TTVLSIQGLEAYVKPGDLVMDVGCGSGVLSIAAAKLGADKVNAYDLDEIAVKSTKLNSKLNQIHESVKVKQNNLLEGVQQ
EADVIVSNILAEIIVRFVDDAWSNLKAGGYFITSGIIQNKKQLVIDNLTKQGFEVISLNEMEDWVSIVAKKPSEK

Sequences:

>Translated_315_residues
MKWSEISIHTTNEAIEPISNILHETGASGLVIEDPLDLERVEKAEFGELYDLDPALYPEEGVRIKAYLPMNSFLGETVEE
IKSAINQLLIYDIDLGKNEVSLSEVHEEEWATAWKKYYKPVKISNRITITPTWEEYTPVSSDELIIELDPGMAFGTGTHP
TTVLSIQGLEAYVKPGDLVMDVGCGSGVLSIAAAKLGADKVNAYDLDEIAVKSTKLNSKLNQIHESVKVKQNNLLEGVQQ
EADVIVSNILAEIIVRFVDDAWSNLKAGGYFITSGIIQNKKQLVIDNLTKQGFEVISLNEMEDWVSIVAKKPSEK
>Mature_315_residues
MKWSEISIHTTNEAIEPISNILHETGASGLVIEDPLDLERVEKAEFGELYDLDPALYPEEGVRIKAYLPMNSFLGETVEE
IKSAINQLLIYDIDLGKNEVSLSEVHEEEWATAWKKYYKPVKISNRITITPTWEEYTPVSSDELIIELDPGMAFGTGTHP
TTVLSIQGLEAYVKPGDLVMDVGCGSGVLSIAAAKLGADKVNAYDLDEIAVKSTKLNSKLNQIHESVKVKQNNLLEGVQQ
EADVIVSNILAEIIVRFVDDAWSNLKAGGYFITSGIIQNKKQLVIDNLTKQGFEVISLNEMEDWVSIVAKKPSEK

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=270, Percent_Identity=29.2592592592593, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_OCEIH (Q8EPW5)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692887.1
- ProteinModelPortal:   Q8EPW5
- SMR:   Q8EPW5
- GeneID:   1018443
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1966
- NMPDR:   fig|221109.1.peg.1966
- HOGENOM:   HBG584653
- OMA:   IELNPGM
- ProtClustDB:   PRK00517
- BioCyc:   OIHE221109:OB1966-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34894; Mature: 34894

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWSEISIHTTNEAIEPISNILHETGASGLVIEDPLDLERVEKAEFGELYDLDPALYPEE
CCCCEEEEEECHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCEECCCCCCCCCC
GVRIKAYLPMNSFLGETVEEIKSAINQLLIYDIDLGKNEVSLSEVHEEEWATAWKKYYKP
CCEEEEEECCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
VKISNRITITPTWEEYTPVSSDELIIELDPGMAFGTGTHPTTVLSIQGLEAYVKPGDLVM
EEECCEEEEEECHHHCCCCCCCCEEEEECCCCEECCCCCCEEEEEEECCEEEECCCCEEE
DVGCGSGVLSIAAAKLGADKVNAYDLDEIAVKSTKLNSKLNQIHESVKVKQNNLLEGVQQ
ECCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EADVIVSNILAEIIVRFVDDAWSNLKAGGYFITSGIIQNKKQLVIDNLTKQGFEVISLNE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHCCHHHHHHHHHHCCCEEEEECH
MEDWVSIVAKKPSEK
HHHHHHHHHCCCCCC
>Mature Secondary Structure
MKWSEISIHTTNEAIEPISNILHETGASGLVIEDPLDLERVEKAEFGELYDLDPALYPEE
CCCCEEEEEECHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCEECCCCCCCCCC
GVRIKAYLPMNSFLGETVEEIKSAINQLLIYDIDLGKNEVSLSEVHEEEWATAWKKYYKP
CCEEEEEECCHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
VKISNRITITPTWEEYTPVSSDELIIELDPGMAFGTGTHPTTVLSIQGLEAYVKPGDLVM
EEECCEEEEEECHHHCCCCCCCCEEEEECCCCEECCCCCCEEEEEEECCEEEECCCCEEE
DVGCGSGVLSIAAAKLGADKVNAYDLDEIAVKSTKLNSKLNQIHESVKVKQNNLLEGVQQ
ECCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EADVIVSNILAEIIVRFVDDAWSNLKAGGYFITSGIIQNKKQLVIDNLTKQGFEVISLNE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHCCHHHHHHHHHHCCCEEEEECH
MEDWVSIVAKKPSEK
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376