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The map label for this gene is glcT [H]

Identifier: 23099338

GI number: 23099338

Start: 1917658

End: 1918500

Strand: Reverse

Name: glcT [H]

Synonym: OB1883

Alternate gene names: 23099338

Gene position: 1918500-1917658 (Counterclockwise)

Preceding gene: 23099339

Following gene: 23099337

Centisome position: 52.84

GC content: 28.59

Gene sequence:

>843_bases
ATGTCCGATTTTATAGTGAAGAAACCATTGAACAATAACGTATTAATAGCACAAGATAATTATCAGAATGAAGTGGTATT
AATAGGGAGTGGAATAGGCTTTAATTTTAAAGAGAACGATTCTGTTGAGGAAGAATTCGTGGAGAAATTATTTGTCTTAC
GTGATCAAGAACAACAAGATCAATATAAAAAAATAGTACCTCAGATTGATGAATATTTACTTCAAAAAATCATTGATTCC
ATTAATATGATTCAAAAAAGGTCTAGTGAAATATTAAATGAAAAAGTTCACGTTGCTTTAACGGATCACTTATTATTTGC
GATTAATCGTTTAGAAAAAGGAATGGCTATCATAAATCCATTCTTATCTGAAACAAAGATTCTATATCCTTTAGAATATG
AAATTGCAGCTGATATAGTTGATTTTTTAAACCAACAATTAGATATTAATTTACCCGATGGTGAAATTGGTTTTATTGCA
TTACATGTTCATAGTGCTATATACAACAGAAAAATATCTGATATTAATCGATACTCTCAATTAATTACCCAATTAATTAA
TATAATTGAAACTAAATTGAGTATAAAGATTGATAGAGCAGGTATTGAGTACATTCGTTTGGTACGTCATATCAGATATA
CTATTGATCGATTGGTAGAAGGAGAAGTTGTACAAGAACCTAAAAAAATAGCGGAATTACTGAAAACAGAATATCCAATT
TGCTATAATTTGAGTTGGAAACTGATGAAAATTATACAGCAAACCTTAAAAAAACCAGTGTATGAAGCCGAAGCTGTTTA
TTTGACAATGCATTTACAACGTCTTTATCAAAAATATGAATAG

Upstream 100 bases:

>100_bases
TTATTAATTGACTCTTATTCAAGTCCATTAATTTTTATAAATTTCTTGCATTTGTGTTACAATTATATTTACTTAAAGAT
TGTTATAGGAGAAAGGTAAT

Downstream 100 bases:

>100_bases
ATTATGTACTGCTGATACAATTAGGCATGGGTAGATAAATGCTCAGTCGTTAAGCTAACTATTTAACGGTTGTTTGCAAA
AAAACTCATGTTTTTTTATG

Product: transcriptional antiterminator

Products: NA

Alternate protein names: RNA-binding antitermination protein GlcT [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MSDFIVKKPLNNNVLIAQDNYQNEVVLIGSGIGFNFKENDSVEEEFVEKLFVLRDQEQQDQYKKIVPQIDEYLLQKIIDS
INMIQKRSSEILNEKVHVALTDHLLFAINRLEKGMAIINPFLSETKILYPLEYEIAADIVDFLNQQLDINLPDGEIGFIA
LHVHSAIYNRKISDINRYSQLITQLINIIETKLSIKIDRAGIEYIRLVRHIRYTIDRLVEGEVVQEPKKIAELLKTEYPI
CYNLSWKLMKIIQQTLKKPVYEAEAVYLTMHLQRLYQKYE

Sequences:

>Translated_280_residues
MSDFIVKKPLNNNVLIAQDNYQNEVVLIGSGIGFNFKENDSVEEEFVEKLFVLRDQEQQDQYKKIVPQIDEYLLQKIIDS
INMIQKRSSEILNEKVHVALTDHLLFAINRLEKGMAIINPFLSETKILYPLEYEIAADIVDFLNQQLDINLPDGEIGFIA
LHVHSAIYNRKISDINRYSQLITQLINIIETKLSIKIDRAGIEYIRLVRHIRYTIDRLVEGEVVQEPKKIAELLKTEYPI
CYNLSWKLMKIIQQTLKKPVYEAEAVYLTMHLQRLYQKYE
>Mature_279_residues
SDFIVKKPLNNNVLIAQDNYQNEVVLIGSGIGFNFKENDSVEEEFVEKLFVLRDQEQQDQYKKIVPQIDEYLLQKIIDSI
NMIQKRSSEILNEKVHVALTDHLLFAINRLEKGMAIINPFLSETKILYPLEYEIAADIVDFLNQQLDINLPDGEIGFIAL
HVHSAIYNRKISDINRYSQLITQLINIIETKLSIKIDRAGIEYIRLVRHIRYTIDRLVEGEVVQEPKKIAELLKTEYPIC
YNLSWKLMKIIQQTLKKPVYEAEAVYLTMHLQRLYQKYE

Specific function: Mediates the positive regulation of the glucose PTS operon (ptsGHI) by functioning as an antiterminator factor of transcription via its interaction with the RNA-antiterminator (RAT) sequence located upstream of the ptsG gene. The RNA-binding domain of Glc

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PRD domains [H]

Homologues:

Organism=Escherichia coli, GI1790160, Length=275, Percent_Identity=25.4545454545455, Blast_Score=134, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004341
- InterPro:   IPR011608
- InterPro:   IPR001550 [H]

Pfam domain/function: PF03123 CAT_RBD; PF00874 PRD [H]

EC number: NA

Molecular weight: Translated: 32830; Mature: 32698

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFIVKKPLNNNVLIAQDNYQNEVVLIGSGIGFNFKENDSVEEEFVEKLFVLRDQEQQD
CCCCEEECCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHH
QYKKIVPQIDEYLLQKIIDSINMIQKRSSEILNEKVHVALTDHLLFAINRLEKGMAIINP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLSETKILYPLEYEIAADIVDFLNQQLDINLPDGEIGFIALHVHSAIYNRKISDINRYSQ
HHHCCEEEEEEHHHHHHHHHHHHCCCEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
LITQLINIIETKLSIKIDRAGIEYIRLVRHIRYTIDRLVEGEVVQEPKKIAELLKTEYPI
HHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHCCCCE
CYNLSWKLMKIIQQTLKKPVYEAEAVYLTMHLQRLYQKYE
EECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDFIVKKPLNNNVLIAQDNYQNEVVLIGSGIGFNFKENDSVEEEFVEKLFVLRDQEQQD
CCCEEECCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHH
QYKKIVPQIDEYLLQKIIDSINMIQKRSSEILNEKVHVALTDHLLFAINRLEKGMAIINP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLSETKILYPLEYEIAADIVDFLNQQLDINLPDGEIGFIALHVHSAIYNRKISDINRYSQ
HHHCCEEEEEEHHHHHHHHHHHHCCCEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHH
LITQLINIIETKLSIKIDRAGIEYIRLVRHIRYTIDRLVEGEVVQEPKKIAELLKTEYPI
HHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHHHHHCCCCE
CYNLSWKLMKIIQQTLKKPVYEAEAVYLTMHLQRLYQKYE
EECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11902727; 9384377 [H]