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The map label for this gene is ptsG [H]

Identifier: 23099337

GI number: 23099337

Start: 1915496

End: 1917523

Strand: Reverse

Name: ptsG [H]

Synonym: OB1882

Alternate gene names: 23099337

Gene position: 1917523-1915496 (Counterclockwise)

Preceding gene: 23099338

Following gene: 23099336

Centisome position: 52.82

GC content: 35.65

Gene sequence:

>2028_bases
ATGTTTAAGAAGGCATTTGGTCTATTACAGAAGATAGGTAAAGCACTTATGTTGCCAGTTGCATTATTACCAGTCGCTGG
GTTGTTGCTAGGTCTTGGTAACGCAGTACAGCAGAATACAGTGTTAGAGTATCTTCCATTCTTACATATGGAGTGGATTC
AGTTAATTGCTACAGTTATGGAAGATGCTGGTGGTATTATTTTTGATAATTTACCATTGATATTTGCTATTGGTGTATCG
ATAGGGCTTGCAAGTGATGGAGCTGCGGGGCTAGCTGCATTAGTCGGATATTTAGTCTTAAATCAAGTTATGGGATCTTG
GATTGGTGTAACTTCTAAAATGATTGAATCTGACCCTAGTTTTGCATCTGTTTTAGGTATCCCAACTTTACAAACAGGTG
TATTCGGAGGAATTATTGTCGGACTAATTGCTGCCTTTTGTTATAACCGATTTCATGATATTGAAATGCCTTCTTTCTTA
GGTTTTTTTGCTGGAAAGCGATTTGTTCCTATAGCTACTGCTGGGTGTTCATTTGTAATAGGTATATTGCTCATGTTTAT
TTGGCCGCCGGTACAAGATGCGATGAATAGTGCATCATATTGGTTAATTGAAGAAGGTACATATGTAGCAGTCTTCTTAT
TTGGATTTATTAAACGATTATTAATTCCGTTCGGACTTCATCATATTTTTCACGCACCTTTTTGGTATGAATTTGGATCA
TTCGAGACTGAAGCTGGTAATATTGTAAGAGGGGATATGGCGATTTTTTTTGCTCAATTAAAAGATGGAGTAGAATTCAC
AGCTGGTCACTTTATGGCTGGGGAATTCCCAATCATGATGTTTGGTTTACCTGCCGCAGCTCTAGCAATGTACCATGCTG
CTAAGCCAGAAAAAAAGAAATTAGTTGCAGGTTTACTTGTATCAGGAGCACTAACATCTTTCTTAACAGGAATTACAGAA
CCTCTTGAGTTTTCTTTTATGTTTTTATCACCAATTTTATTTTTGATCCATGCACTTTTAGATGGTTTATCTTTTGTTTT
GATGACATATTTTCATGTGAATATAGGATTTACTTTCTCAGGAGGAGCTATTGACTTTGTGCTTTTTGGTATTCTGCCAG
GACAAGAACCGTGGTGGATAACGATTATACTTGGGTTATTTTTTGCGATAATATATTATTTTCTATTCCGTTACTTCATT
AAAAAGTTTAATTTACTAACGCCAGGTAGAGAAGAATCAGATGATCATAAATATAGTCCTAGTTCTGAAAAAAGCGACTT
AGCGTTTGACGTAGTAGAAGCGATAGGTGGATTACAAAATATTACTCATTTGGATGCTTGTATTACAAGATTGCGGGTAT
CTGTCGATTCTATTCAAAAAGTAAATAAGGTTAGATTAAAAAAAATAGGAGCATCAGGAGTCTTAGTGGTGGGAAATAAC
GTTCAAGCAATATTTGGACCTCGCTCCGAGACGATAAAAGGACAAATACAGGATATTATTTTAGGTAAGGTACCTCGACT
AGGACAAGAGTTTGAATATCCTGTTGTAGAGGAGCCTATATCCGTTAATGATGAAATAATCGTATCACCATTAACTGGAC
AAATGATACCGATAACAGATGTGTCTGACCCAGTATTTTCTGGTAAATTGATGGGAGAAGGTTTTGCCATCATTCCGGAA
GATGGAACGATTGTTTCTCCTGTGGATGGGGAAATCATTCATATTTTTCCGACCAATCATGCAATTGGAGTCCAATCAGA
GGAAGGGACAGAAATATTAATACATGCTGGATTGGATACAGTTAACTTAAATGGAAAAGGATTTAATATTTTTGTTGATG
AAAATCAATTTGTTAAAGCTGGGCAAGCATTATTAAAAGTAGATCTAGACTATTTAGAAAAACAAGGATTTTCAACAGTT
ACTCCTGTTGTATTCACAAACATACATGATTTAGCTTATATACATTTACTAGAGGAAAAAGTTGAAAAAGGACAATCCAA
TATTATAGCCTTCAAAAGGGTACAATAA

Upstream 100 bases:

>100_bases
ATAAATGCTCAGTCGTTAAGCTAACTATTTAACGGTTGTTTGCAAAAAAACTCATGTTTTTTTATGTTCGTAATCAATTT
TTAATGAAGGGGGGATAAAT

Downstream 100 bases:

>100_bases
GAGCCGTCTGAGTAAAATATCTTTTTTGCTTGGGGGCTTTTCTTTTTGTTCACTAAAAGTGGACCGGATATGCTAAAATC
GTTTATATGATATGGTTGAA

Product: PTS system, glucose-specific enzyme II, A component

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 675; Mature: 675

Protein sequence:

>675_residues
MFKKAFGLLQKIGKALMLPVALLPVAGLLLGLGNAVQQNTVLEYLPFLHMEWIQLIATVMEDAGGIIFDNLPLIFAIGVS
IGLASDGAAGLAALVGYLVLNQVMGSWIGVTSKMIESDPSFASVLGIPTLQTGVFGGIIVGLIAAFCYNRFHDIEMPSFL
GFFAGKRFVPIATAGCSFVIGILLMFIWPPVQDAMNSASYWLIEEGTYVAVFLFGFIKRLLIPFGLHHIFHAPFWYEFGS
FETEAGNIVRGDMAIFFAQLKDGVEFTAGHFMAGEFPIMMFGLPAAALAMYHAAKPEKKKLVAGLLVSGALTSFLTGITE
PLEFSFMFLSPILFLIHALLDGLSFVLMTYFHVNIGFTFSGGAIDFVLFGILPGQEPWWITIILGLFFAIIYYFLFRYFI
KKFNLLTPGREESDDHKYSPSSEKSDLAFDVVEAIGGLQNITHLDACITRLRVSVDSIQKVNKVRLKKIGASGVLVVGNN
VQAIFGPRSETIKGQIQDIILGKVPRLGQEFEYPVVEEPISVNDEIIVSPLTGQMIPITDVSDPVFSGKLMGEGFAIIPE
DGTIVSPVDGEIIHIFPTNHAIGVQSEEGTEILIHAGLDTVNLNGKGFNIFVDENQFVKAGQALLKVDLDYLEKQGFSTV
TPVVFTNIHDLAYIHLLEEKVEKGQSNIIAFKRVQ

Sequences:

>Translated_675_residues
MFKKAFGLLQKIGKALMLPVALLPVAGLLLGLGNAVQQNTVLEYLPFLHMEWIQLIATVMEDAGGIIFDNLPLIFAIGVS
IGLASDGAAGLAALVGYLVLNQVMGSWIGVTSKMIESDPSFASVLGIPTLQTGVFGGIIVGLIAAFCYNRFHDIEMPSFL
GFFAGKRFVPIATAGCSFVIGILLMFIWPPVQDAMNSASYWLIEEGTYVAVFLFGFIKRLLIPFGLHHIFHAPFWYEFGS
FETEAGNIVRGDMAIFFAQLKDGVEFTAGHFMAGEFPIMMFGLPAAALAMYHAAKPEKKKLVAGLLVSGALTSFLTGITE
PLEFSFMFLSPILFLIHALLDGLSFVLMTYFHVNIGFTFSGGAIDFVLFGILPGQEPWWITIILGLFFAIIYYFLFRYFI
KKFNLLTPGREESDDHKYSPSSEKSDLAFDVVEAIGGLQNITHLDACITRLRVSVDSIQKVNKVRLKKIGASGVLVVGNN
VQAIFGPRSETIKGQIQDIILGKVPRLGQEFEYPVVEEPISVNDEIIVSPLTGQMIPITDVSDPVFSGKLMGEGFAIIPE
DGTIVSPVDGEIIHIFPTNHAIGVQSEEGTEILIHAGLDTVNLNGKGFNIFVDENQFVKAGQALLKVDLDYLEKQGFSTV
TPVVFTNIHDLAYIHLLEEKVEKGQSNIIAFKRVQ
>Mature_675_residues
MFKKAFGLLQKIGKALMLPVALLPVAGLLLGLGNAVQQNTVLEYLPFLHMEWIQLIATVMEDAGGIIFDNLPLIFAIGVS
IGLASDGAAGLAALVGYLVLNQVMGSWIGVTSKMIESDPSFASVLGIPTLQTGVFGGIIVGLIAAFCYNRFHDIEMPSFL
GFFAGKRFVPIATAGCSFVIGILLMFIWPPVQDAMNSASYWLIEEGTYVAVFLFGFIKRLLIPFGLHHIFHAPFWYEFGS
FETEAGNIVRGDMAIFFAQLKDGVEFTAGHFMAGEFPIMMFGLPAAALAMYHAAKPEKKKLVAGLLVSGALTSFLTGITE
PLEFSFMFLSPILFLIHALLDGLSFVLMTYFHVNIGFTFSGGAIDFVLFGILPGQEPWWITIILGLFFAIIYYFLFRYFI
KKFNLLTPGREESDDHKYSPSSEKSDLAFDVVEAIGGLQNITHLDACITRLRVSVDSIQKVNKVRLKKIGASGVLVVGNN
VQAIFGPRSETIKGQIQDIILGKVPRLGQEFEYPVVEEPISVNDEIIVSPLTGQMIPITDVSDPVFSGKLMGEGFAIIPE
DGTIVSPVDGEIIHIFPTNHAIGVQSEEGTEILIHAGLDTVNLNGKGFNIFVDENQFVKAGQALLKVDLDYLEKQGFSTV
TPVVFTNIHDLAYIHLLEEKVEKGQSNIIAFKRVQ

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786894, Length=683, Percent_Identity=40.2635431918009, Blast_Score=454, Evalue=1e-128,
Organism=Escherichia coli, GI1787343, Length=504, Percent_Identity=45.6349206349206, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1787908, Length=512, Percent_Identity=37.3046875, Blast_Score=322, Evalue=3e-89,
Organism=Escherichia coli, GI1788757, Length=147, Percent_Identity=41.4965986394558, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1790159, Length=124, Percent_Identity=43.5483870967742, Blast_Score=114, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 73846; Mature: 73846

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS51093 PTS_EIIA_TYPE_1 ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKAFGLLQKIGKALMLPVALLPVAGLLLGLGNAVQQNTVLEYLPFLHMEWIQLIATVM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EDAGGIIFDNLPLIFAIGVSIGLASDGAAGLAALVGYLVLNQVMGSWIGVTSKMIESDPS
HHCCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FASVLGIPTLQTGVFGGIIVGLIAAFCYNRFHDIEMPSFLGFFAGKRFVPIATAGCSFVI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEECCHHHHHH
GILLMFIWPPVQDAMNSASYWLIEEGTYVAVFLFGFIKRLLIPFGLHHIFHAPFWYEFGS
HHHHHHHCCCHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
FETEAGNIVRGDMAIFFAQLKDGVEFTAGHFMAGEFPIMMFGLPAAALAMYHAAKPEKKK
CCCCCCCEEEHHHHHHHHHHHCCCEECCCCEECCCCCEEEECCCHHHHHHHHCCCCHHHH
LVAGLLVSGALTSFLTGITEPLEFSFMFLSPILFLIHALLDGLSFVLMTYFHVNIGFTFS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEC
GGAIDFVLFGILPGQEPWWITIILGLFFAIIYYFLFRYFIKKFNLLTPGREESDDHKYSP
CCHHEEHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SSEKSDLAFDVVEAIGGLQNITHLDACITRLRVSVDSIQKVNKVRLKKIGASGVLVVGNN
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
VQAIFGPRSETIKGQIQDIILGKVPRLGQEFEYPVVEEPISVNDEIIVSPLTGQMIPITD
EEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECC
VSDPVFSGKLMGEGFAIIPEDGTIVSPVDGEIIHIFPTNHAIGVQSEEGTEILIHAGLDT
CCCCHHCCEEECCCEEEECCCCCEECCCCCCEEEEEECCCEEECCCCCCCEEEEEECCCE
VNLNGKGFNIFVDENQFVKAGQALLKVDLDYLEKQGFSTVTPVVFTNIHDLAYIHLLEEK
EEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHH
VEKGQSNIIAFKRVQ
HHCCCCCEEEEEECC
>Mature Secondary Structure
MFKKAFGLLQKIGKALMLPVALLPVAGLLLGLGNAVQQNTVLEYLPFLHMEWIQLIATVM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EDAGGIIFDNLPLIFAIGVSIGLASDGAAGLAALVGYLVLNQVMGSWIGVTSKMIESDPS
HHCCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FASVLGIPTLQTGVFGGIIVGLIAAFCYNRFHDIEMPSFLGFFAGKRFVPIATAGCSFVI
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEECCHHHHHH
GILLMFIWPPVQDAMNSASYWLIEEGTYVAVFLFGFIKRLLIPFGLHHIFHAPFWYEFGS
HHHHHHHCCCHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
FETEAGNIVRGDMAIFFAQLKDGVEFTAGHFMAGEFPIMMFGLPAAALAMYHAAKPEKKK
CCCCCCCEEEHHHHHHHHHHHCCCEECCCCEECCCCCEEEECCCHHHHHHHHCCCCHHHH
LVAGLLVSGALTSFLTGITEPLEFSFMFLSPILFLIHALLDGLSFVLMTYFHVNIGFTFS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEC
GGAIDFVLFGILPGQEPWWITIILGLFFAIIYYFLFRYFIKKFNLLTPGREESDDHKYSP
CCHHEEHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SSEKSDLAFDVVEAIGGLQNITHLDACITRLRVSVDSIQKVNKVRLKKIGASGVLVVGNN
CCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
VQAIFGPRSETIKGQIQDIILGKVPRLGQEFEYPVVEEPISVNDEIIVSPLTGQMIPITD
EEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEECC
VSDPVFSGKLMGEGFAIIPEDGTIVSPVDGEIIHIFPTNHAIGVQSEEGTEILIHAGLDT
CCCCHHCCEEECCCEEEECCCCCEECCCCCCEEEEEECCCEEECCCCCCCEEEEEECCCE
VNLNGKGFNIFVDENQFVKAGQALLKVDLDYLEKQGFSTVTPVVFTNIHDLAYIHLLEEK
EEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCHHHHHHHHHHHHH
VEKGQSNIIAFKRVQ
HHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]