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The map label for this gene is yqiR [H]

Identifier: 23099325

GI number: 23099325

Start: 1901899

End: 1903950

Strand: Reverse

Name: yqiR [H]

Synonym: OB1870

Alternate gene names: 23099325

Gene position: 1903950-1901899 (Counterclockwise)

Preceding gene: 23099327

Following gene: 23099324

Centisome position: 52.44

GC content: 35.23

Gene sequence:

>2052_bases
ATGAAACAAGTATTAATTGTTGGTGGCGGTAAAGGCGGAACTGCATTATTTCATTTATTACAGGCAACTAGTCGGATGAA
CATAAAGGCAGTTGTTGATCTAAATTTAACTGCGCCCGCTATACAACTGGCGAAAAATGCAGGTATTCCAGTGAGTACTA
ATTGGAAAGATTGGATTTTTGAAGAAGTGGATATTGTTTTAGAGGCAACAGGTGTGGAATCAGTATTAGAAGAAATTATA
GAAGTACGGCCTCGAAAAACAGTAGTAGTTCCAGGTTCAGTTGCTAATATAATCTCTGAATTGCTATATGAAAAAGAATA
CCTTGTTGAAAAAGTAAAATCACAAGCAAACAGATTGGAACTTATCCTCAATCATATTCATGACGGAATGATTGTTATTG
ATAAAAATGAAAAGGTAGAGCTTTTAAATAATCGGGCAGAAAATATTTTAAATAAAAAAGAGTTTGAGTATAAAGGGAAA
CACATCTATGATTTGTTACCTTCGAGTAGGTTACCGAATGTTTTAAAATCCCAAAGAAGAGAATTAAACCAAAAAACAAT
TTTAGATAATGGTAAGAAAGTAATTTCTACCCGAATCCCAATTATTAGTAAAACCGGTGATTTAGTTGGTGCTTTTGCTG
TATTTAAAGATATTACAGAGGTTGTCAAGCTTGCTGAAGAAAATACGGATTTAAATGAAATAAAAACGATGTTAGAAGCG
ATTATAAATTCATCAGATGAGGCGATAAGTGTAGTAGATGAAAAAGGAAATGGTCTCATCATTAATCCTGCGTATACTCG
AATTACCGGGCTAACGGAAGAAGATGTAATTGGAAGACCAGCGACTGTAGACATCTCAGAGGGAGAAAGTATGCACCTCA
AAGTTCTAGAAACGCGTCGGGTGGTTAGAGGCGTACATATGAAAGTAGGCCCTCATAACAAAGAAGTGATTGTTAATGTT
GCCCCTGTCATTGTACAAGGAAAAATTAAGGGTAGTGTTGGGGTTTTACATGATGTTTCAGAAATTCAGTTATTGACGAA
AGAATTAAAACGAGCAAGGCAAATTATCCGTAACTTAGAAGCTCGGTATACATTTGACGATATAATTGGAAGTTCTCCAG
AAATGAAGTTAGCGCTTGAACAAGCAAAAGTAGGTGCAAAGACTCCGGCAATTGTGTTGCTACGTGGAGAGTCAGGCACA
GGAAAAGAACTGTTTGCTCATGCAATTCATAACGAAAGTGATCGCAAGCACCATAAGTTTATTCGAGTGAATTGTGCTGC
GCTTTCAGAATCGCTATTAGAAAGTGAGCTATTTGGGTATGAAGAAGGAGCTTTTACTGGTGCAAAAACTGGTGGTAAAA
AAGGCTTCTTCGAGGAAGCGAATGGAGGAAGTATCTTTTTAGATGAAATAGGTGAATTGTCACTAACCATGCAAGCGAAA
TTACTTCGAGTACTTCAAGAAAAGGAAGTAGTACGTGTCGGTGGGTCCACCCCTATTTCTATAGATATACGCGTGATTGC
AGCAACGAATGTAAATCTTGAAAAAGCGATAATGAACCGTACATTTAGAGAAGATTTATATTATCGGATAAATAAGCTTC
CAATTACAGTTCCTGCAATAAAAGAACGAATTTCTGATTTACCAGAGCTTATACAACATATCATTCATAAAATGAACAAT
GAATATGGGAGAAATGTTGTTAGAATATCTACGAAGGCTGTTGATCAATTAATGAAATATCATTGGCCTGGCAATGTACG
AGAATTAGAAAATGTCGTAAGTAGAGCGATGATATTTATGGATAATACAGAAGAAGTACTTGATGTTAAGCATTTACCTA
ACATCATTGCTAGAAAACATGAAGATACTTACGTAAAGCTAAACTCAGACGGTGAAATCACCAAATTGCAAGATGCTTTG
GATGTCTATGAAAAACAGTATATTAATATGGTATTTGAACGATGTAATAAAAATAAAACGAAGACAGCAAAAGAACTACA
AATTTCTGTACGTAACTTATACTATAAGTTAGATAAATACAACCTTGAATAA

Upstream 100 bases:

>100_bases
TATATCAAATTCTATAGAAAATAGAAAAAAATATAGTTTGCTAATAAATGCAGAATATCATAAGATGTAGATATGCAAAA
TAATGCAAGGTGGAGAGATG

Downstream 100 bases:

>100_bases
TTTTTCCTGCAAAATATTGCAGGAATGAAAGTTATTGCGTGCTTTCAAAGGCTGTATATCAATGTCTGCTTGGTATTATT
AGTTGGCATACAATTTGCAA

Product: sigma-L-dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 683; Mature: 683

Protein sequence:

>683_residues
MKQVLIVGGGKGGTALFHLLQATSRMNIKAVVDLNLTAPAIQLAKNAGIPVSTNWKDWIFEEVDIVLEATGVESVLEEII
EVRPRKTVVVPGSVANIISELLYEKEYLVEKVKSQANRLELILNHIHDGMIVIDKNEKVELLNNRAENILNKKEFEYKGK
HIYDLLPSSRLPNVLKSQRRELNQKTILDNGKKVISTRIPIISKTGDLVGAFAVFKDITEVVKLAEENTDLNEIKTMLEA
IINSSDEAISVVDEKGNGLIINPAYTRITGLTEEDVIGRPATVDISEGESMHLKVLETRRVVRGVHMKVGPHNKEVIVNV
APVIVQGKIKGSVGVLHDVSEIQLLTKELKRARQIIRNLEARYTFDDIIGSSPEMKLALEQAKVGAKTPAIVLLRGESGT
GKELFAHAIHNESDRKHHKFIRVNCAALSESLLESELFGYEEGAFTGAKTGGKKGFFEEANGGSIFLDEIGELSLTMQAK
LLRVLQEKEVVRVGGSTPISIDIRVIAATNVNLEKAIMNRTFREDLYYRINKLPITVPAIKERISDLPELIQHIIHKMNN
EYGRNVVRISTKAVDQLMKYHWPGNVRELENVVSRAMIFMDNTEEVLDVKHLPNIIARKHEDTYVKLNSDGEITKLQDAL
DVYEKQYINMVFERCNKNKTKTAKELQISVRNLYYKLDKYNLE

Sequences:

>Translated_683_residues
MKQVLIVGGGKGGTALFHLLQATSRMNIKAVVDLNLTAPAIQLAKNAGIPVSTNWKDWIFEEVDIVLEATGVESVLEEII
EVRPRKTVVVPGSVANIISELLYEKEYLVEKVKSQANRLELILNHIHDGMIVIDKNEKVELLNNRAENILNKKEFEYKGK
HIYDLLPSSRLPNVLKSQRRELNQKTILDNGKKVISTRIPIISKTGDLVGAFAVFKDITEVVKLAEENTDLNEIKTMLEA
IINSSDEAISVVDEKGNGLIINPAYTRITGLTEEDVIGRPATVDISEGESMHLKVLETRRVVRGVHMKVGPHNKEVIVNV
APVIVQGKIKGSVGVLHDVSEIQLLTKELKRARQIIRNLEARYTFDDIIGSSPEMKLALEQAKVGAKTPAIVLLRGESGT
GKELFAHAIHNESDRKHHKFIRVNCAALSESLLESELFGYEEGAFTGAKTGGKKGFFEEANGGSIFLDEIGELSLTMQAK
LLRVLQEKEVVRVGGSTPISIDIRVIAATNVNLEKAIMNRTFREDLYYRINKLPITVPAIKERISDLPELIQHIIHKMNN
EYGRNVVRISTKAVDQLMKYHWPGNVRELENVVSRAMIFMDNTEEVLDVKHLPNIIARKHEDTYVKLNSDGEITKLQDAL
DVYEKQYINMVFERCNKNKTKTAKELQISVRNLYYKLDKYNLE
>Mature_683_residues
MKQVLIVGGGKGGTALFHLLQATSRMNIKAVVDLNLTAPAIQLAKNAGIPVSTNWKDWIFEEVDIVLEATGVESVLEEII
EVRPRKTVVVPGSVANIISELLYEKEYLVEKVKSQANRLELILNHIHDGMIVIDKNEKVELLNNRAENILNKKEFEYKGK
HIYDLLPSSRLPNVLKSQRRELNQKTILDNGKKVISTRIPIISKTGDLVGAFAVFKDITEVVKLAEENTDLNEIKTMLEA
IINSSDEAISVVDEKGNGLIINPAYTRITGLTEEDVIGRPATVDISEGESMHLKVLETRRVVRGVHMKVGPHNKEVIVNV
APVIVQGKIKGSVGVLHDVSEIQLLTKELKRARQIIRNLEARYTFDDIIGSSPEMKLALEQAKVGAKTPAIVLLRGESGT
GKELFAHAIHNESDRKHHKFIRVNCAALSESLLESELFGYEEGAFTGAKTGGKKGFFEEANGGSIFLDEIGELSLTMQAK
LLRVLQEKEVVRVGGSTPISIDIRVIAATNVNLEKAIMNRTFREDLYYRINKLPITVPAIKERISDLPELIQHIIHKMNN
EYGRNVVRISTKAVDQLMKYHWPGNVRELENVVSRAMIFMDNTEEVLDVKHLPNIIARKHEDTYVKLNSDGEITKLQDAL
DVYEKQYINMVFERCNKNKTKTAKELQISVRNLYYKLDKYNLE

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3829

COG function: function code KT; Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=345, Percent_Identity=43.4782608695652, Blast_Score=263, Evalue=4e-71,
Organism=Escherichia coli, GI1789233, Length=472, Percent_Identity=34.1101694915254, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1790437, Length=312, Percent_Identity=43.2692307692308, Blast_Score=250, Evalue=3e-67,
Organism=Escherichia coli, GI87082117, Length=246, Percent_Identity=48.3739837398374, Blast_Score=244, Evalue=2e-65,
Organism=Escherichia coli, GI1786524, Length=331, Percent_Identity=38.6706948640483, Blast_Score=241, Evalue=9e-65,
Organism=Escherichia coli, GI1789087, Length=252, Percent_Identity=46.8253968253968, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1788905, Length=313, Percent_Identity=41.2140575079872, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI1790299, Length=348, Percent_Identity=35.9195402298851, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI1787583, Length=380, Percent_Identity=33.9473684210526, Blast_Score=209, Evalue=5e-55,
Organism=Escherichia coli, GI87082152, Length=313, Percent_Identity=38.3386581469649, Blast_Score=208, Evalue=9e-55,
Organism=Escherichia coli, GI87081872, Length=322, Percent_Identity=34.472049689441, Blast_Score=182, Evalue=7e-47,
Organism=Escherichia coli, GI87081858, Length=427, Percent_Identity=27.1662763466042, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1789828, Length=252, Percent_Identity=35.3174603174603, Blast_Score=141, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR002197
- InterPro:   IPR016040
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 76734; Mature: 76734

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS50112 PAS ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVLIVGGGKGGTALFHLLQATSRMNIKAVVDLNLTAPAIQLAKNAGIPVSTNWKDWIF
CCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCHHHHHH
EEVDIVLEATGVESVLEEIIEVRPRKTVVVPGSVANIISELLYEKEYLVEKVKSQANRLE
HHHHHEEEECCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LILNHIHDGMIVIDKNEKVELLNNRAENILNKKEFEYKGKHIYDLLPSSRLPNVLKSQRR
HHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCHHHHCCCCCHHHHCCCCCCCHHHHHHHH
ELNQKTILDNGKKVISTRIPIISKTGDLVGAFAVFKDITEVVKLAEENTDLNEIKTMLEA
HHHHHHHHCCCCEEEHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IINSSDEAISVVDEKGNGLIINPAYTRITGLTEEDVIGRPATVDISEGESMHLKVLETRR
HHCCCCCEEEEEECCCCEEEECCHHHHCCCCCCHHCCCCCCEEEECCCCCEEEEHHHHHH
VVRGVHMKVGPHNKEVIVNVAPVIVQGKIKGSVGVLHDVSEIQLLTKELKRARQIIRNLE
HHHHCEEEECCCCCEEEEEEECEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ARYTFDDIIGSSPEMKLALEQAKVGAKTPAIVLLRGESGTGKELFAHAIHNESDRKHHKF
HCEEHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCHHHE
IRVNCAALSESLLESELFGYEEGAFTGAKTGGKKGFFEEANGGSIFLDEIGELSLTMQAK
EEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHH
LLRVLQEKEVVRVGGSTPISIDIRVIAATNVNLEKAIMNRTFREDLYYRINKLPITVPAI
HHHHHHHCCCEEECCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEHHHH
KERISDLPELIQHIIHKMNNEYGRNVVRISTKAVDQLMKYHWPGNVRELENVVSRAMIFM
HHHHHHHHHHHHHHHHHHCHHHCCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHEEEE
DNTEEVLDVKHLPNIIARKHEDTYVKLNSDGEITKLQDALDVYEKQYINMVFERCNKNKT
CCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KTAKELQISVRNLYYKLDKYNLE
CHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKQVLIVGGGKGGTALFHLLQATSRMNIKAVVDLNLTAPAIQLAKNAGIPVSTNWKDWIF
CCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCHHHHHH
EEVDIVLEATGVESVLEEIIEVRPRKTVVVPGSVANIISELLYEKEYLVEKVKSQANRLE
HHHHHEEEECCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LILNHIHDGMIVIDKNEKVELLNNRAENILNKKEFEYKGKHIYDLLPSSRLPNVLKSQRR
HHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCHHHHCCCCCHHHHCCCCCCCHHHHHHHH
ELNQKTILDNGKKVISTRIPIISKTGDLVGAFAVFKDITEVVKLAEENTDLNEIKTMLEA
HHHHHHHHCCCCEEEHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IINSSDEAISVVDEKGNGLIINPAYTRITGLTEEDVIGRPATVDISEGESMHLKVLETRR
HHCCCCCEEEEEECCCCEEEECCHHHHCCCCCCHHCCCCCCEEEECCCCCEEEEHHHHHH
VVRGVHMKVGPHNKEVIVNVAPVIVQGKIKGSVGVLHDVSEIQLLTKELKRARQIIRNLE
HHHHCEEEECCCCCEEEEEEECEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ARYTFDDIIGSSPEMKLALEQAKVGAKTPAIVLLRGESGTGKELFAHAIHNESDRKHHKF
HCEEHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCCHHHE
IRVNCAALSESLLESELFGYEEGAFTGAKTGGKKGFFEEANGGSIFLDEIGELSLTMQAK
EEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHH
LLRVLQEKEVVRVGGSTPISIDIRVIAATNVNLEKAIMNRTFREDLYYRINKLPITVPAI
HHHHHHHCCCEEECCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEHHHH
KERISDLPELIQHIIHKMNNEYGRNVVRISTKAVDQLMKYHWPGNVRELENVVSRAMIFM
HHHHHHHHHHHHHHHHHHCHHHCCCEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHEEEE
DNTEEVLDVKHLPNIIARKHEDTYVKLNSDGEITKLQDALDVYEKQYINMVFERCNKNKT
CCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KTAKELQISVRNLYYKLDKYNLE
CHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]