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The map label for this gene is prsW

Identifier: 23099262

GI number: 23099262

Start: 1843301

End: 1843948

Strand: Reverse

Name: prsW

Synonym: OB1807

Alternate gene names: 23099262

Gene position: 1843948-1843301 (Counterclockwise)

Preceding gene: 23099263

Following gene: 23099261

Centisome position: 50.79

GC content: 28.86

Gene sequence:

>648_bases
ATGTTGTCTATATTATCAGCTGGTATAGCACCTGCTTTAGCTTTGCTATCGTATATATATTTAAAGGATAAAATAACGGA
ACCTATTTGGTTAATTATACGAATGTTTATCTTAGGTGCTTTACTCGTACTACCTATAATGTTTATCCAATATGCAATAT
CTAGTGAATTTAATTACGATTCCATTTTCATCGAGGCTTTTTTCCAAATCGCGTTACTTGAAGAGTTTTTTAAGTGGTTT
GTATTTATGTTTGTTATATACCAACATGAAGAATTTGATAATCATTATGATGGTATTGTTTATGCTAGTTCACTTAGTTT
AGGATTTGCTTCTATTGAGAATATCCTTTATTTAATTACCAATGGAATAGAGTATGCATTTCTTCGAGCCGTTTTTCCAG
TATCTTCTCACGCGTTATTTGGAATTATTATGGGATATTATTTAGGAAAAGCCAAAACTCATACTAATTATAAGAAAAAA
AATCTCACTCTCGCATTCTTATTACCATTTCTTCTCCACGGAATATATAATTTTATTTTAAAAGGTTTTAGCAGTTTTAC
ATTAATTCTGACTCCTTTTATGGTTTTATTATGGATAATTGCGTTGTACAGATTAAAAAGAGCGAATGAAAATACAATAA
TCAATTAA

Upstream 100 bases:

>100_bases
TATTAAACTCGATTTCTTAATGGAAACTGGCTGATGAATGTAAAATGAAATTACTATATGCTAAGGAGAACGAATTGGGA
GTAGAGAAGAGGTATATTTT

Downstream 100 bases:

>100_bases
GGAACTATCTAGCATGTCAGCTCGTTGACTGTTTGATAGTTTTTTTATTTCTTATCTGAATGAATAAAAAGGAAAATAAC
ACAAAAAATAGTGGTGCATC

Product: hypothetical protein

Products: NA

Alternate protein names: Protease responsible for activating sigma-W

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MLSILSAGIAPALALLSYIYLKDKITEPIWLIIRMFILGALLVLPIMFIQYAISSEFNYDSIFIEAFFQIALLEEFFKWF
VFMFVIYQHEEFDNHYDGIVYASSLSLGFASIENILYLITNGIEYAFLRAVFPVSSHALFGIIMGYYLGKAKTHTNYKKK
NLTLAFLLPFLLHGIYNFILKGFSSFTLILTPFMVLLWIIALYRLKRANENTIIN

Sequences:

>Translated_215_residues
MLSILSAGIAPALALLSYIYLKDKITEPIWLIIRMFILGALLVLPIMFIQYAISSEFNYDSIFIEAFFQIALLEEFFKWF
VFMFVIYQHEEFDNHYDGIVYASSLSLGFASIENILYLITNGIEYAFLRAVFPVSSHALFGIIMGYYLGKAKTHTNYKKK
NLTLAFLLPFLLHGIYNFILKGFSSFTLILTPFMVLLWIIALYRLKRANENTIIN
>Mature_215_residues
MLSILSAGIAPALALLSYIYLKDKITEPIWLIIRMFILGALLVLPIMFIQYAISSEFNYDSIFIEAFFQIALLEEFFKWF
VFMFVIYQHEEFDNHYDGIVYASSLSLGFASIENILYLITNGIEYAFLRAVFPVSSHALFGIIMGYYLGKAKTHTNYKKK
NLTLAFLLPFLLHGIYNFILKGFSSFTLILTPFMVLLWIIALYRLKRANENTIIN

Specific function: Is responsible for Site-1 cleavage of the RsiW anti- sigma factor. This results, after two other proteolytic steps catalyzed by the RasP and ClpXP proteases, in the release of SigW and the transcription activation of the genes under the control of the sig

COG id: COG2339

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease prsW family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRSW_OCEIH (Q8EQA1)

Other databases:

- EMBL:   BA000028
- RefSeq:   NP_692728.1
- GeneID:   1018301
- GenomeReviews:   BA000028_GR
- KEGG:   oih:OB1807
- NMPDR:   fig|221109.1.peg.1808
- HOGENOM:   HBG549045
- OMA:   DEPYDGI
- ProtClustDB:   CLSK873083
- BioCyc:   OIHE221109:OB1807-MONOMER

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 24855; Mature: 24855

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe6a3874)-; HASH(0xf598e38)-; HASH(0xf291698)-; HASH(0xf67c09c)-; HASH(0xdd64940)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSILSAGIAPALALLSYIYLKDKITEPIWLIIRMFILGALLVLPIMFIQYAISSEFNYD
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SIFIEAFFQIALLEEFFKWFVFMFVIYQHEEFDNHYDGIVYASSLSLGFASIENILYLIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHH
NGIEYAFLRAVFPVSSHALFGIIMGYYLGKAKTHTNYKKKNLTLAFLLPFLLHGIYNFIL
CCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
KGFSSFTLILTPFMVLLWIIALYRLKRANENTIIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
>Mature Secondary Structure
MLSILSAGIAPALALLSYIYLKDKITEPIWLIIRMFILGALLVLPIMFIQYAISSEFNYD
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SIFIEAFFQIALLEEFFKWFVFMFVIYQHEEFDNHYDGIVYASSLSLGFASIENILYLIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHH
NGIEYAFLRAVFPVSSHALFGIIMGYYLGKAKTHTNYKKKNLTLAFLLPFLLHGIYNFIL
CCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
KGFSSFTLILTPFMVLLWIIALYRLKRANENTIIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12235376