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The map label for this gene is gerCC [H]

Identifier: 23099243

GI number: 23099243

Start: 1825010

End: 1825981

Strand: Reverse

Name: gerCC [H]

Synonym: OB1788

Alternate gene names: 23099243

Gene position: 1825981-1825010 (Counterclockwise)

Preceding gene: 23099244

Following gene: 23099242

Centisome position: 50.3

GC content: 34.16

Gene sequence:

>972_bases
ATGAAACTACCAAAAATTTATGGCTTTTTAAAGAAAGATATGGAAAGTATAGAATCTGCATTACAGGATAGTATACAGGC
AAATCATCCCGTGTTACGTGATGCATCAACTGAATTATTACATGCAGGGGGAAAGCGAATTCGTCCTGTTTTTGTTTTGC
TATCATCTCAATTAGGAAATTACGATCTTTCTAAGATTAAAAAAGTTGCAGTAACATTAGAATTAATACATATGGCTACC
CTCGTTCACGACGATGTGATCGATGAAGCAGAGCTAAGAAGAGGAAAACCGACGACAGCTTCTATATATGGTAATCGTGT
AGCCATGTATACGGGAGATTATATACTCGCAAGGGCATTAGAAGAAATAACAGAAATACCAGACCCAAGAGTACATCAAT
TACTTTCCAAAACGTTAGTAGAAGTGTCGATTGGAGAAATTGAACAGATTGAATATAAATTTAACTGGGAACAAAACTTC
CGTGATTATCTGCGTCGTATAAAAAGAAAAACTGCGCTGTTAATAGCTAGTAGTTGCAAACTAGGAGCAATAGTTGGAGG
TTTAAATGATTATCAAACTAATAAGCTATACCAATATGGTTATTACATAGGAATGTCTTATCAAATTATTGATGATATCT
TAGATTTTACATCTACTTCCAAAGAACTCGGTAAGCCTGCTGGCAATGACTTATTACAAGGAAATATTACACTCCCGGTT
TTATATGCCATGGAAGATAAGACCTTCAAACAATCACTTTTTAATGTATTTTCAAAAGATGGTCATGTCACAACCAATGA
AATGAAGACACTGATACAACACTTAAAAAGAACAGATGCTATTAAAAGAAGTTATGCTGTAAGTGATATGTATTTATCCA
AAGCATTAACTGCATTAGATGAAATACCGGCTTCTCGTGCAAAAAAAACTCTCCAAGATATTGCAACATATATCGGAAAA
AGAAGATCCTAA

Upstream 100 bases:

>100_bases
GAAATGAAAAGTTATACAGGTGGAGTTGCTGCAATGCATATGGGCTTTAAAGCATCTCAATAGTACGTAGAATTGTAAAA
GGTAAAATAAGGTGACTTAC

Downstream 100 bases:

>100_bases
GTAATTGTTATTTTTAAGAAAATTTGATATTATTTTATAGGTTACTTATTTAAATACATAAGTTGGGGTGATTTTATGGA
GAAAACATTTTTAATGGTAA

Product: heptaprenyl diphosphate synthase component II

Products: NA

Alternate protein names: HEPPP synthase subunit 2; Spore germination protein C3 [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MKLPKIYGFLKKDMESIESALQDSIQANHPVLRDASTELLHAGGKRIRPVFVLLSSQLGNYDLSKIKKVAVTLELIHMAT
LVHDDVIDEAELRRGKPTTASIYGNRVAMYTGDYILARALEEITEIPDPRVHQLLSKTLVEVSIGEIEQIEYKFNWEQNF
RDYLRRIKRKTALLIASSCKLGAIVGGLNDYQTNKLYQYGYYIGMSYQIIDDILDFTSTSKELGKPAGNDLLQGNITLPV
LYAMEDKTFKQSLFNVFSKDGHVTTNEMKTLIQHLKRTDAIKRSYAVSDMYLSKALTALDEIPASRAKKTLQDIATYIGK
RRS

Sequences:

>Translated_323_residues
MKLPKIYGFLKKDMESIESALQDSIQANHPVLRDASTELLHAGGKRIRPVFVLLSSQLGNYDLSKIKKVAVTLELIHMAT
LVHDDVIDEAELRRGKPTTASIYGNRVAMYTGDYILARALEEITEIPDPRVHQLLSKTLVEVSIGEIEQIEYKFNWEQNF
RDYLRRIKRKTALLIASSCKLGAIVGGLNDYQTNKLYQYGYYIGMSYQIIDDILDFTSTSKELGKPAGNDLLQGNITLPV
LYAMEDKTFKQSLFNVFSKDGHVTTNEMKTLIQHLKRTDAIKRSYAVSDMYLSKALTALDEIPASRAKKTLQDIATYIGK
RRS
>Mature_323_residues
MKLPKIYGFLKKDMESIESALQDSIQANHPVLRDASTELLHAGGKRIRPVFVLLSSQLGNYDLSKIKKVAVTLELIHMAT
LVHDDVIDEAELRRGKPTTASIYGNRVAMYTGDYILARALEEITEIPDPRVHQLLSKTLVEVSIGEIEQIEYKFNWEQNF
RDYLRRIKRKTALLIASSCKLGAIVGGLNDYQTNKLYQYGYYIGMSYQIIDDILDFTSTSKELGKPAGNDLLQGNITLPV
LYAMEDKTFKQSLFNVFSKDGHVTTNEMKTLIQHLKRTDAIKRSYAVSDMYLSKALTALDEIPASRAKKTLQDIATYIGK
RRS

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=288, Percent_Identity=32.6388888888889, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI169808399, Length=335, Percent_Identity=24.4776119402985, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4758430, Length=228, Percent_Identity=25.8771929824561, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI83700220, Length=228, Percent_Identity=25.8771929824561, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1789578, Length=315, Percent_Identity=28.2539682539683, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1786623, Length=216, Percent_Identity=29.6296296296296, Blast_Score=78, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17505681, Length=241, Percent_Identity=32.7800829875519, Blast_Score=144, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6319475, Length=306, Percent_Identity=30.3921568627451, Blast_Score=148, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6325188, Length=225, Percent_Identity=23.5555555555556, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24651612, Length=303, Percent_Identity=30.03300330033, Blast_Score=150, Evalue=9e-37,
Organism=Drosophila melanogaster, GI281365769, Length=224, Percent_Identity=24.1071428571429, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24660002, Length=224, Percent_Identity=24.1071428571429, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 36563; Mature: 36563

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPKIYGFLKKDMESIESALQDSIQANHPVLRDASTELLHAGGKRIRPVFVLLSSQLGN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHCCCCHHHHHHHHHHHHCCC
YDLSKIKKVAVTLELIHMATLVHDDVIDEAELRRGKPTTASIYGNRVAMYTGDYILARAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCEEEECCCEEEEEECHHHHHHHH
EEITEIPDPRVHQLLSKTLVEVSIGEIEQIEYKFNWEQNFRDYLRRIKRKTALLIASSCK
HHHHHCCCHHHHHHHHHHHHHHHHCCHHEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCC
LGAIVGGLNDYQTNKLYQYGYYIGMSYQIIDDILDFTSTSKELGKPAGNDLLQGNITLPV
HHHHHCCCCCHHCCCEEEEHEEECCHHHHHHHHHHHCCCHHHHCCCCCCCCEECCCCEEE
LYAMEDKTFKQSLFNVFSKDGHVTTNEMKTLIQHLKRTDAIKRSYAVSDMYLSKALTALD
EEEECCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIPASRAKKTLQDIATYIGKRRS
HCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKLPKIYGFLKKDMESIESALQDSIQANHPVLRDASTELLHAGGKRIRPVFVLLSSQLGN
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHCCCCHHHHHHHHHHHHCCC
YDLSKIKKVAVTLELIHMATLVHDDVIDEAELRRGKPTTASIYGNRVAMYTGDYILARAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCEEEECCCEEEEEECHHHHHHHH
EEITEIPDPRVHQLLSKTLVEVSIGEIEQIEYKFNWEQNFRDYLRRIKRKTALLIASSCK
HHHHHCCCHHHHHHHHHHHHHHHHCCHHEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCC
LGAIVGGLNDYQTNKLYQYGYYIGMSYQIIDDILDFTSTSKELGKPAGNDLLQGNITLPV
HHHHHCCCCCHHCCCEEEEHEEECCHHHHHHHHHHHCCCHHHHCCCCCCCCEECCCCEEE
LYAMEDKTFKQSLFNVFSKDGHVTTNEMKTLIQHLKRTDAIKRSYAVSDMYLSKALTALD
EEEECCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIPASRAKKTLQDIATYIGKRRS
HCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 2121900; 9720033 [H]