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The map label for this gene is dinG [H]

Identifier: 23099217

GI number: 23099217

Start: 1801021

End: 1803840

Strand: Reverse

Name: dinG [H]

Synonym: OB1762

Alternate gene names: 23099217

Gene position: 1803840-1801021 (Counterclockwise)

Preceding gene: 23099218

Following gene: 23099216

Centisome position: 49.69

GC content: 33.94

Gene sequence:

>2820_bases
ATGAATCGATTTGTCGTCATTGATCTAGAAACAACTGGACATGCACCATCAAAAAATGACAAAATTATTGAAATTGGCAT
GGTAATTATTGAGGGTGATGAAATTATTGATACAAAAACGACCTTCTTTAATCCAGGTCAACCAATTCCACCTTTTATTA
CTAATTTAACAGGAATTTCTGATGACGATGTTGCGGATGCTCCTCTATTTACAGAAAAAGCTTTGTCCATAAAATCTATA
TTGGAAGATAGTTATATCATTGCACATAACGTTAATTTTGATTTAGGGTTTCTAAATGCTGAGCTGAAAGAGAATGGAAT
AGATCGATTGCATAATCAAGTTTTGGATACTGTGGAATTATCAAGGATTTTATTCCCGACAGCTCCTGGGTATAAATTAA
GTCAATTATCAGATCATTTTAATTTACAACATGATGATCCACATAGAGCTTTATCTGATGCATATGTAACAGCGAAGTTA
TTTCAAAAATTGATGGATAAAATAAATCAATTACCATATGAAACCATAGAACAGTGGCTTAAACTAGAAGGTGCTTTCAT
TTCTGATATCAAAGAAATATTATTGAATAGGTTGGATGAATTAGCTTTTTCTATCGATCAGGATTCCGCTATACATACCT
TTCAAGGTTTAGCATTTCATATGAATGATGTAGAAGCGAAACAAGTACATAATGTAGATACATCCTTTGGTAATTACTTA
GATACAATTTATGAAGACGGTGGAAAACTATCCGAACACCTTTCCATGTATGAAAAACGGGCAGGCCAACAAGAAATGTC
AGAAACCATTTATGATGCCTTTACCTCTAGTAATCATGCACTAATAGAAGCTGGTACTGGTACTGGAAAATCACTAGCTT
ACCTTCTCCCAGCTGTATACTATGCCGTAAAGCAAAATCAAAAGGTGATTATTAGCACACATACCACACAGCTACAATCT
CAGCTGTTAGAAGAGGAGATTCCACTTATACATGCGATAAGCGATATTCCATTTCAAGCAGCATTGTTAAAAGGAAAAAA
TCATTACATTAGTTTGGAAAAATTCTCTATTGAACTTTATGAGCAAGGTCAAGATAATTATGATATAGCACTTACAAAAG
CAATGTTGTTAATATGGATAACGGAGACAAATACCGGTGATGTCGAAGAGGTACAATTACCGACCAGTGGATATATATTT
TTCAGAAAGATATCCGCCGATACGGAAAAGGCAGTCAACCCTCAATCACCTTGGTTCCAATATTCGTATTATCAGCAAGC
GAGAAAAAAAGCACAACGGGCAAATATAATAATTACAAACCATGCGTTACTATGTACGGATATGTTTAATGATTATGCAT
TTCTCCCTTCCTATCAACGGGTAATTATCGACGAAGCACATCATTTTGAAGAACAAGCAGCACATCATTATGGTTTAAAA
ATGGACTATATGAGTATGCAATTTACATGTAATCAATTGGGTTCTTCAGAGGAAGATAAACTATTTGGTAATTTTGTACA
AGCTTATCAATTATCTAATAGTGATATACCTCTATACGAATGGAATGATACGTTAAAGAGTGCAAAGCAAGAGATTGAAG
ATCTTTTTCAAGCAATATATTATTATGTATCCAAACAGCATTTGAGTAACCAAGCTTTAAGCGATGTAGGTAGGATACAG
TACCGGATGGATACGGAGAAGGAAACTGGTGATTCGTGGCAAGTAATATTAGATATGTCTTCTCGACTTAGTTTATACTT
TCGAGATCTTATCCACATTCTTTTTATGGTTGAACAAAGAATTAACCAAGAAGATAACTCTGAAAAAAATCATCGAGAAG
AATTATTACAAATGGTCGAGTTGTTACAACGGTATATAGATGGATTAGAGCTGATGTTTTATTCTGGTGGGGAAGTAGAA
CAAATTAAATGGATAGAAATAGATAAAAAAGGTCAGAATCACTCTGTATTTTTATATAGTGAACCAGCAGATGTAGCAGA
GCTATTAGAAAATGAATTTTTCCATGAAAAAGAAAGTGTTGTAATGACAAGTGCTACATTAACGATGAATCATTCATTTT
CCTTTATGCAGAAGCGGTTAGGCTTATCTTCACATTCATGTATTACAGAACAAATTGAATCGCCATTCGCATATGATCAA
CAAGTTCAAATGTTTATTCCCAATGATTTTCCGGACATCAAGTACGGAAATATAGATGATTTCGTATATGCAGTTGCAGA
AGCAATAATTTCCTTGGCTGAAATAACATCTGGAAGAATGCTTGTATTGTTTACTTCGTATGATATGTTAAGAAAAGCTT
ACTATGTATTAAAAGAAGCGATGGAAAAAGACAAATATATGCTTATTGGACAGGGAATCACAAGTGGTAGTAGAGCAAGA
TTGAAGAAGAATTTCCAATCATTTGACCAAGCGATACTTTTAGGGACAAGTTCATTTTGGGAAGGTGTAGATATACCAGG
CGATGATCTATCATCTTTAGTAATTGTTAGATTACCTTTTCAACCACCGAATCATCCCGTTATTGAAGCGAAATCTGCTA
TGCTGAAGAAGCAGAAACAAAATCCGTTTATGGAACTTTCATTGCCTAATGCAGTTATTAAATTTAAACAGGGATTTGGC
AGATTAATACGTTCCTCAAACGATAGAGGGATTGTCTTTGTATGTGATGCTCGAATTGTTAATGCAAGATATGGAAAATA
TTTCACAGAATCAATTCCCAAAGTTCCAATCCATTATGATTCTACACATAAACTAATCGATAAAGCGGAGCAATGGTATA
AAAAAAATGATGCCTTATAA

Upstream 100 bases:

>100_bases
TAAACAAATGATAGAACAAGAACCTCCGATGACGGTTTTGTAAAGAGCTATTATCCGTTTTCCCATTTTAATTTTTGGTA
GAAAGGGAGGTGAGCAGTAT

Downstream 100 bases:

>100_bases
CAAGGCATCATTACATTGAAGAACAATCGAATTGGTCGGTAAAATTTTTACATCAAATCAGCAATCACCATTTTGACGTG
TTATTATTATTTACAGATGA

Product: bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 939; Mature: 939

Protein sequence:

>939_residues
MNRFVVIDLETTGHAPSKNDKIIEIGMVIIEGDEIIDTKTTFFNPGQPIPPFITNLTGISDDDVADAPLFTEKALSIKSI
LEDSYIIAHNVNFDLGFLNAELKENGIDRLHNQVLDTVELSRILFPTAPGYKLSQLSDHFNLQHDDPHRALSDAYVTAKL
FQKLMDKINQLPYETIEQWLKLEGAFISDIKEILLNRLDELAFSIDQDSAIHTFQGLAFHMNDVEAKQVHNVDTSFGNYL
DTIYEDGGKLSEHLSMYEKRAGQQEMSETIYDAFTSSNHALIEAGTGTGKSLAYLLPAVYYAVKQNQKVIISTHTTQLQS
QLLEEEIPLIHAISDIPFQAALLKGKNHYISLEKFSIELYEQGQDNYDIALTKAMLLIWITETNTGDVEEVQLPTSGYIF
FRKISADTEKAVNPQSPWFQYSYYQQARKKAQRANIIITNHALLCTDMFNDYAFLPSYQRVIIDEAHHFEEQAAHHYGLK
MDYMSMQFTCNQLGSSEEDKLFGNFVQAYQLSNSDIPLYEWNDTLKSAKQEIEDLFQAIYYYVSKQHLSNQALSDVGRIQ
YRMDTEKETGDSWQVILDMSSRLSLYFRDLIHILFMVEQRINQEDNSEKNHREELLQMVELLQRYIDGLELMFYSGGEVE
QIKWIEIDKKGQNHSVFLYSEPADVAELLENEFFHEKESVVMTSATLTMNHSFSFMQKRLGLSSHSCITEQIESPFAYDQ
QVQMFIPNDFPDIKYGNIDDFVYAVAEAIISLAEITSGRMLVLFTSYDMLRKAYYVLKEAMEKDKYMLIGQGITSGSRAR
LKKNFQSFDQAILLGTSSFWEGVDIPGDDLSSLVIVRLPFQPPNHPVIEAKSAMLKKQKQNPFMELSLPNAVIKFKQGFG
RLIRSSNDRGIVFVCDARIVNARYGKYFTESIPKVPIHYDSTHKLIDKAEQWYKKNDAL

Sequences:

>Translated_939_residues
MNRFVVIDLETTGHAPSKNDKIIEIGMVIIEGDEIIDTKTTFFNPGQPIPPFITNLTGISDDDVADAPLFTEKALSIKSI
LEDSYIIAHNVNFDLGFLNAELKENGIDRLHNQVLDTVELSRILFPTAPGYKLSQLSDHFNLQHDDPHRALSDAYVTAKL
FQKLMDKINQLPYETIEQWLKLEGAFISDIKEILLNRLDELAFSIDQDSAIHTFQGLAFHMNDVEAKQVHNVDTSFGNYL
DTIYEDGGKLSEHLSMYEKRAGQQEMSETIYDAFTSSNHALIEAGTGTGKSLAYLLPAVYYAVKQNQKVIISTHTTQLQS
QLLEEEIPLIHAISDIPFQAALLKGKNHYISLEKFSIELYEQGQDNYDIALTKAMLLIWITETNTGDVEEVQLPTSGYIF
FRKISADTEKAVNPQSPWFQYSYYQQARKKAQRANIIITNHALLCTDMFNDYAFLPSYQRVIIDEAHHFEEQAAHHYGLK
MDYMSMQFTCNQLGSSEEDKLFGNFVQAYQLSNSDIPLYEWNDTLKSAKQEIEDLFQAIYYYVSKQHLSNQALSDVGRIQ
YRMDTEKETGDSWQVILDMSSRLSLYFRDLIHILFMVEQRINQEDNSEKNHREELLQMVELLQRYIDGLELMFYSGGEVE
QIKWIEIDKKGQNHSVFLYSEPADVAELLENEFFHEKESVVMTSATLTMNHSFSFMQKRLGLSSHSCITEQIESPFAYDQ
QVQMFIPNDFPDIKYGNIDDFVYAVAEAIISLAEITSGRMLVLFTSYDMLRKAYYVLKEAMEKDKYMLIGQGITSGSRAR
LKKNFQSFDQAILLGTSSFWEGVDIPGDDLSSLVIVRLPFQPPNHPVIEAKSAMLKKQKQNPFMELSLPNAVIKFKQGFG
RLIRSSNDRGIVFVCDARIVNARYGKYFTESIPKVPIHYDSTHKLIDKAEQWYKKNDAL
>Mature_939_residues
MNRFVVIDLETTGHAPSKNDKIIEIGMVIIEGDEIIDTKTTFFNPGQPIPPFITNLTGISDDDVADAPLFTEKALSIKSI
LEDSYIIAHNVNFDLGFLNAELKENGIDRLHNQVLDTVELSRILFPTAPGYKLSQLSDHFNLQHDDPHRALSDAYVTAKL
FQKLMDKINQLPYETIEQWLKLEGAFISDIKEILLNRLDELAFSIDQDSAIHTFQGLAFHMNDVEAKQVHNVDTSFGNYL
DTIYEDGGKLSEHLSMYEKRAGQQEMSETIYDAFTSSNHALIEAGTGTGKSLAYLLPAVYYAVKQNQKVIISTHTTQLQS
QLLEEEIPLIHAISDIPFQAALLKGKNHYISLEKFSIELYEQGQDNYDIALTKAMLLIWITETNTGDVEEVQLPTSGYIF
FRKISADTEKAVNPQSPWFQYSYYQQARKKAQRANIIITNHALLCTDMFNDYAFLPSYQRVIIDEAHHFEEQAAHHYGLK
MDYMSMQFTCNQLGSSEEDKLFGNFVQAYQLSNSDIPLYEWNDTLKSAKQEIEDLFQAIYYYVSKQHLSNQALSDVGRIQ
YRMDTEKETGDSWQVILDMSSRLSLYFRDLIHILFMVEQRINQEDNSEKNHREELLQMVELLQRYIDGLELMFYSGGEVE
QIKWIEIDKKGQNHSVFLYSEPADVAELLENEFFHEKESVVMTSATLTMNHSFSFMQKRLGLSSHSCITEQIESPFAYDQ
QVQMFIPNDFPDIKYGNIDDFVYAVAEAIISLAEITSGRMLVLFTSYDMLRKAYYVLKEAMEKDKYMLIGQGITSGSRAR
LKKNFQSFDQAILLGTSSFWEGVDIPGDDLSSLVIVRLPFQPPNHPVIEAKSAMLKKQKQNPFMELSLPNAVIKFKQGFG
RLIRSSNDRGIVFVCDARIVNARYGKYFTESIPKVPIHYDSTHKLIDKAEQWYKKNDAL

Specific function: Probable helicase involved in DNA repair and perhaps also replication [H]

COG id: COG1199

COG function: function code KL; Rad3-related DNA helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788110, Length=259, Percent_Identity=34.7490347490347, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1787018, Length=720, Percent_Identity=24.4444444444444, Blast_Score=152, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR006054
- InterPro:   IPR006310
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR014013
- InterPro:   IPR006555
- InterPro:   IPR001650
- InterPro:   IPR006935
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 107606; Mature: 107606

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFVVIDLETTGHAPSKNDKIIEIGMVIIEGDEIIDTKTTFFNPGQPIPPFITNLTGIS
CCCEEEEEEECCCCCCCCCCCEEEEEEEEEECCCEEECCCCEECCCCCCCHHHHHCCCCC
DDDVADAPLFTEKALSIKSILEDSYIIAHNVNFDLGFLNAELKENGIDRLHNQVLDTVEL
CCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHH
SRILFPTAPGYKLSQLSDHFNLQHDDPHRALSDAYVTAKLFQKLMDKINQLPYETIEQWL
HHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KLEGAFISDIKEILLNRLDELAFSIDQDSAIHTFQGLAFHMNDVEAKQVHNVDTSFGNYL
HHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEECCCCCHHHHHCCCHHHHHHH
DTIYEDGGKLSEHLSMYEKRAGQQEMSETIYDAFTSSNHALIEAGTGTGKSLAYLLPAVY
HHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
YAVKQNQKVIISTHTTQLQSQLLEEEIPLIHAISDIPFQAALLKGKNHYISLEKFSIELY
HHHHCCCEEEEEECHHHHHHHHHHHHCCEEEECCCCCHHHHHHCCCCCEEEEEHEEEEEE
EQGQDNYDIALTKAMLLIWITETNTGDVEEVQLPTSGYIFFRKISADTEKAVNPQSPWFQ
CCCCCCCCHHHEEEEEEEEEEECCCCCCEEEECCCCCEEEEEEECCCHHHCCCCCCCCEE
YSYYQQARKKAQRANIIITNHALLCTDMFNDYAFLPSYQRVIIDEAHHFEEQAAHHYGLK
HHHHHHHHHHHHHCCEEEECCEEEEHHHHCCEECCCCHHHHHHHHHHHHHHHHHHHCCCE
MDYMSMQFTCNQLGSSEEDKLFGNFVQAYQLSNSDIPLYEWNDTLKSAKQEIEDLFQAIY
EECHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHH
YYVSKQHLSNQALSDVGRIQYRMDTEKETGDSWQVILDMSSRLSLYFRDLIHILFMVEQR
HHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHH
INQEDNSEKNHREELLQMVELLQRYIDGLELMFYSGGEVEQIKWIEIDKKGQNHSVFLYS
HCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEEEEECCCCCCEEEEEE
EPADVAELLENEFFHEKESVVMTSATLTMNHSFSFMQKRLGLSSHSCITEQIESPFAYDQ
CCHHHHHHHHHHHHCCCCCEEEEEEEEEECCCHHHHHHHHCCCCCHHHHHHHCCCCCCCC
QVQMFIPNDFPDIKYGNIDDFVYAVAEAIISLAEITSGRMLVLFTSYDMLRKAYYVLKEA
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHH
MEKDKYMLIGQGITSGSRARLKKNFQSFDQAILLGTSSFWEGVDIPGDDLSSLVIVRLPF
HCCCCEEEEECCCCCCHHHHHHHHHHHHHHEEEEECCHHCCCCCCCCCCCCCEEEEEECC
QPPNHPVIEAKSAMLKKQKQNPFMELSLPNAVIKFKQGFGRLIRSSNDRGIVFVCDARIV
CCCCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEECCEEE
NARYGKYFTESIPKVPIHYDSTHKLIDKAEQWYKKNDAL
CCHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNRFVVIDLETTGHAPSKNDKIIEIGMVIIEGDEIIDTKTTFFNPGQPIPPFITNLTGIS
CCCEEEEEEECCCCCCCCCCCEEEEEEEEEECCCEEECCCCEECCCCCCCHHHHHCCCCC
DDDVADAPLFTEKALSIKSILEDSYIIAHNVNFDLGFLNAELKENGIDRLHNQVLDTVEL
CCCCCCCCCHHHHHHHHHHHHCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHH
SRILFPTAPGYKLSQLSDHFNLQHDDPHRALSDAYVTAKLFQKLMDKINQLPYETIEQWL
HHHHCCCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KLEGAFISDIKEILLNRLDELAFSIDQDSAIHTFQGLAFHMNDVEAKQVHNVDTSFGNYL
HHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEECCCCCHHHHHCCCHHHHHHH
DTIYEDGGKLSEHLSMYEKRAGQQEMSETIYDAFTSSNHALIEAGTGTGKSLAYLLPAVY
HHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHH
YAVKQNQKVIISTHTTQLQSQLLEEEIPLIHAISDIPFQAALLKGKNHYISLEKFSIELY
HHHHCCCEEEEEECHHHHHHHHHHHHCCEEEECCCCCHHHHHHCCCCCEEEEEHEEEEEE
EQGQDNYDIALTKAMLLIWITETNTGDVEEVQLPTSGYIFFRKISADTEKAVNPQSPWFQ
CCCCCCCCHHHEEEEEEEEEEECCCCCCEEEECCCCCEEEEEEECCCHHHCCCCCCCCEE
YSYYQQARKKAQRANIIITNHALLCTDMFNDYAFLPSYQRVIIDEAHHFEEQAAHHYGLK
HHHHHHHHHHHHHCCEEEECCEEEEHHHHCCEECCCCHHHHHHHHHHHHHHHHHHHCCCE
MDYMSMQFTCNQLGSSEEDKLFGNFVQAYQLSNSDIPLYEWNDTLKSAKQEIEDLFQAIY
EECHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHH
YYVSKQHLSNQALSDVGRIQYRMDTEKETGDSWQVILDMSSRLSLYFRDLIHILFMVEQR
HHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHH
INQEDNSEKNHREELLQMVELLQRYIDGLELMFYSGGEVEQIKWIEIDKKGQNHSVFLYS
HCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEEEEEECCCCCCEEEEEE
EPADVAELLENEFFHEKESVVMTSATLTMNHSFSFMQKRLGLSSHSCITEQIESPFAYDQ
CCHHHHHHHHHHHHCCCCCEEEEEEEEEECCCHHHHHHHHCCCCCHHHHHHHCCCCCCCC
QVQMFIPNDFPDIKYGNIDDFVYAVAEAIISLAEITSGRMLVLFTSYDMLRKAYYVLKEA
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHH
MEKDKYMLIGQGITSGSRARLKKNFQSFDQAILLGTSSFWEGVDIPGDDLSSLVIVRLPF
HCCCCEEEEECCCCCCHHHHHHHHHHHHHHEEEEECCHHCCCCCCCCCCCCCEEEEEECC
QPPNHPVIEAKSAMLKKQKQNPFMELSLPNAVIKFKQGFGRLIRSSNDRGIVFVCDARIV
CCCCCCCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEECCEEE
NARYGKYFTESIPKVPIHYDSTHKLIDKAEQWYKKNDAL
CCHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]